Estimating the Cost of Raccoon Rabies Variant in Ohio

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Book Synopsis Estimating the Cost of Raccoon Rabies Variant in Ohio by : Leah M. Durbak

Download or read book Estimating the Cost of Raccoon Rabies Variant in Ohio written by Leah M. Durbak and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Raccoon rabies variant (RRV) virus has spread north and west since its introduction to the Virginia/West Virginia border in the late 1970s following the translocation of rabid raccoons from Florida for hunting purposes [60]. In Ohio, the westward spread of RRV has been halted along the Pennsylvania border in northeast Ohio by an oral rabies vaccination (ORV) program 1997 [30]. Given that the immune barrier could be breached, this research aims to estimate the financial impact RRV spread could have on Ohio by extrapolating from the economic experiences of other states that have dealt with an RRV epizootic. Following a literature review of rabies cost models reported in the literature, three broad categories were considered for RRV costs in Ohio [51]. The first category was comprised of public health prevention activities, such as disease surveillance, diagnostic testing and public education campaigns. Secondly, healthcare costs associated with RRV spread were determined to consist of direct (post-exposure prophylaxis biologicals and administration) and indirect (travel, lost wages, childcare healthcare and alternative treatment) costs related to RRV exposure. The third economic category encompassed animal associated costs including companion and livestock vaccination as well as livestock indemnity fees. Once the baseline costs for each input and the expected rate increases due to RRV spread were selected from published resources, a spatial spread model for RRV expansion throughout Ohio was derived. Considering Ohio's topography and the rate of RRV movement through other states, RRV could be expected to cover the state between three and six years after an uncontrolled breach of the ORV barrier. Expenses associated with the variant were calculated using low and high cost estimates using these two timeframes of potential RRV spread, resulting in four cost models. The results from these models estimate the total additional cost due to RRV spread throughout Ohio between $44.3 to $337.7 million during the initial epizootic years. The three major categories considered in this project held similar proportions of the total cost in all four models that were considered. In the low estimation models, public health costs account for roughly 22% of the total cost and animal associated costs for approximately 19%. In the high estimation models, public health expenses accounted for 4% and animal associated costs were about 39% of the total costs. All possible costs attributable to RRV spread could not be included in these models as many cannot or have not been quantified. Nonetheless, the results from this study demonstrate that the economic impact of RRV spread throughout Ohio would be unquestionably widespread and significant. Evaluation of the various cost subcategories, can aid during strategic planning for RRV incursions by providing insight into the areas most amenable to mitigation efforts. For example, education of healthcare providers may reduce the impact of the largest category, healthcare costs, by reducing the inappropriate use of PEP. These results will also help inform local, state and federal policy makers as they make budgetary decisions regarding rabies prevention and ORV programs.

Population Density and Prevalence of Rabies Virus-neutralizing Antibodies in a Northern Ohio Raccoon Population

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Book Synopsis Population Density and Prevalence of Rabies Virus-neutralizing Antibodies in a Northern Ohio Raccoon Population by : Paul Christopher Ramey

Download or read book Population Density and Prevalence of Rabies Virus-neutralizing Antibodies in a Northern Ohio Raccoon Population written by Paul Christopher Ramey and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current oral rabies vaccination (ORV) programs across the eastern USA were established to prevent the westward spread of raccoon (Procyon lotor) rabies. The programs distribute vaccine baits at a density of 75 baits/km2. However, few studies have examined the relationship of bait density and population density to sero-prevalence of rabies virus-neutralizing antibodies (RVNA). I conducted experimental baitings in August 2003 and 2004, 150 km west of the ORV zone (Sandusky, Ohio) where there was no history of raccoon rabies. I collected blood samples from live-trapped raccoons to determine sero-prevalence of RVNA, and teeth to determine prevalence of tetracycline (biomarker in bait). During April-October (2003 and 2004), I evaluated 3 mark-recapture-based estimates of raccoon population density, as well as a line-transect-based method on the 22-km2 U.S. National Aeronautics and Space Administration Plum Brook Station in Erie County, Ohio (USA; 41° 27' N, 82° 42' W). During 2003, 41% of pre-bait serum samples were RVNA positive (>̲ 0.05 IU/ml), but none had titers>̲ 0.25 IU/ml. During the pre-2004 bait drop period (March-August) 21% of samples collected were RVNA positive and 9% had titers>̲ 0.25 lU/ml. After the 2003 and 2004 bait drops (September-October) only 4% of serum samples collected had high titers. Prevalence of tetracycline in post-bait teeth indicated that 17% and 27% of the population ingested baits in 2003 and 2004, respectively. I first calculated annual minimum number known alive (MNKA) density estimates, approximating the protocol used by the U.S. Department of Agriculture Wildlife Services, and estimated an adult population size of 660 raccoons and 594 raccoons during 2003 and 2004, respectively. I also estimated size of the adult population using the catch per unit effort (CPUE) method, which yielded 438 ± 182 raccoons and 527 ± 208 raccoons for 2003 and 2004 respectively. Using program CAPTURE and model Mbh (heterogeneity and trap response), I estimated a population size of 619 ± 83 during 2003 and 765 ± 92 during 2004. Using Distance (version 4.1) and the line-transect data, I estimated 198 raccoons and 220 raccoons for 2003 and 2004, respectively. During 2003 and 2004 both, surveys resulted in density estimates less than the number of unique individuals captured. I note that lack of replication in the MNKA model precludes error estimates. Also, assumptions of equal probability of capture for both the MNKA and CPUE estimates were violated, likely biasing my estimates low. However, the upper limit of the CPUE estimate in both years was similar to mean estimates from the mark-recapture model. I suggest that mark-recapture would serve well in providing density information in ORV planning. Further, in situations where trapping would be difficult due to trap exposures (e.g., urban settings), estimates based on line-transect data from FLIR could provide a baseline to estimate the target population density. I attribute the low proportions of high RVNA titers and tetracycline to the high density of raccoons on the study area. I estimated an adult population of 619 ± 83 (95% CI) raccoons, using 2003 data and model Mbh. Assuming an annual birthrate of 1.5 juveniles per adult, 1,548 raccoons were present at the time of the 2003 baiting, so just under 1 bait was distributed per raccoon, well below the program target of 5 baits/raccoon. A high proportion of RVNA positive raccoons in an area with no history of raccoon rabies or vaccination efforts exemplifies the need for pre-bait serology in order to accurately measure the effect of ORV distribution. I contend that without incorporating pre-bait serology and population density estimates, an ORV program could under-bait high-density populations and overestimate the number of vaccinated animals.

Public Health Reports

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ISBN 13 :
Total Pages : 820 pages
Book Rating : 4.3/5 ( download)

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Download or read book Public Health Reports written by and published by . This book was released on 1998 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Journal of the American Veterinary Medical Association

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ISBN 13 :
Total Pages : 904 pages
Book Rating : 4.3/5 (117 download)

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Book Synopsis Journal of the American Veterinary Medical Association by : American Veterinary Medical Association

Download or read book Journal of the American Veterinary Medical Association written by American Veterinary Medical Association and published by . This book was released on 2013 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1915-49 and 1956- include the Proceedings of the annual meeting of the association.

Emerging Infectious Diseases

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ISBN 13 :
Total Pages : 1142 pages
Book Rating : 4.3/5 (21 download)

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Book Synopsis Emerging Infectious Diseases by :

Download or read book Emerging Infectious Diseases written by and published by . This book was released on 2009 with total page 1142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Public Health Reports

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ISBN 13 :
Total Pages : 824 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Public Health Reports by :

Download or read book Public Health Reports written by and published by . This book was released on 1998 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proceedings - Vertebrate Pest Conference

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ISBN 13 :
Total Pages : 570 pages
Book Rating : 4.3/5 (91 download)

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Download or read book Proceedings - Vertebrate Pest Conference written by and published by . This book was released on 2006 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Morbidity and Mortality Weekly Report

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ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.3/5 (126 download)

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Download or read book Morbidity and Mortality Weekly Report written by and published by . This book was released on 1997 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

History of Rabies in the Americas: From the Pre-Columbian to the Present, Volume I

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Publisher : Springer Nature
ISBN 13 : 3031250524
Total Pages : 328 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis History of Rabies in the Americas: From the Pre-Columbian to the Present, Volume I by : Charles E. Rupprecht

Download or read book History of Rabies in the Americas: From the Pre-Columbian to the Present, Volume I written by Charles E. Rupprecht and published by Springer Nature. This book was released on 2023-04-24 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rabies is one of the oldest known pathogens, is incurable, and has the highest fatality rate of all infectious diseases. The Americas is the only region with bat rabies virus, including vampire bat rabies. The region is rich in cultural references and notable for many discoveries in the field, including the current vaccine potency test, diagnostic assay, conception of oral vaccines for wildlife, the first human survivor and the first successful canine rabies program executed at a broad level. Rabies remains the most important viral zoonosis, with tens of thousands of human fatalities and tens of millions of exposures annually, which can be used to model for other pathogens, such as COVID-19. There is an international effort to eliminate human rabies caused by dogs over the next decade, and the Americas represent the primary region with the greatest proof-of-concept evidence to accomplish this goal. This two-volume set addresses the medical history and modern results of rabies in countries throughout the Americas, including the implications of and on cultural, economic, sociological, and research developments in the region. Volume I presents an overview of concepts critical to the study of rabies in the region, including evolutionary aspects, reservoir ecology and control, elimination efforts, vaccine development, and disease hallmarks and progression. It also analyzes the long-term cultural, social, and economic impacts of the disease in the Americas.

Index Medicus

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ISBN 13 :
Total Pages : 2036 pages
Book Rating : 4.:/5 (319 download)

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Download or read book Index Medicus written by and published by . This book was released on 2003-07 with total page 2036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Wildlife Science

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Publisher : CRC Press
ISBN 13 : 1420007610
Total Pages : 386 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Wildlife Science by : Timothy E. Fulbright

Download or read book Wildlife Science written by Timothy E. Fulbright and published by CRC Press. This book was released on 2007-06-20 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consciously or not, wildlife managers generally act from a theoretical basis, although they may not be fully versed in the details or ramifications of that theory. In practice, the predictions of the practitioners sometimes prove more accurate than those of the theoreticians. Practitioners and theoreticians need to work together, but this proves di

Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations for 2009

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ISBN 13 :
Total Pages : 1072 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations for 2009 by : United States. Congress. House. Committee on Appropriations. Subcommittee on Agriculture, Rural Development, Food and Drug Administration, and Related Agencies

Download or read book Agriculture, Rural Development, Food and Drug Administration, and Related Agencies Appropriations for 2009 written by United States. Congress. House. Committee on Appropriations. Subcommittee on Agriculture, Rural Development, Food and Drug Administration, and Related Agencies and published by . This book was released on 2008 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Addressing Emerging Infectious Disease Threats

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ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Addressing Emerging Infectious Disease Threats by :

Download or read book Addressing Emerging Infectious Disease Threats written by and published by . This book was released on 1994 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This plan addresses the need to improve our ability to identify infectious disease threats and respond to them effectively by improving the public health infrastructure at the local, state and federal levels. The goals of the plan are surveillance (detect, promptly investigate, and monitor emerging pathogens, the diseases they cause, and the factors influencing their emergence); applied research (integrate laboratory science and epidemiology to optimize public health practice); prevention and control (enhance communication of public health information about emerging diseases and ensure prompt implementation of prevention strategies); and infrastructure (strengthen local, state, and federal public health infrastructures to support surveillance and implement prevention and control programs).

Auerbach's Wilderness Medicine

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323396097
Total Pages : 3097 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Auerbach's Wilderness Medicine by : Paul S. Auerbach

Download or read book Auerbach's Wilderness Medicine written by Paul S. Auerbach and published by Elsevier Health Sciences. This book was released on 2016-09-21 with total page 3097 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its 7th edition, Auerbach’s Wilderness Medicine continues to help you quickly and decisively manage medical emergencies encountered in any wilderness or other austere setting! World-renowned authority Dr. Paul Auerbach and 2 new associate editors have assembled a team of experts to offer proven, practical, visual guidance for effectively diagnosing and treating the full range of issues that can occur in situations where time and resources are scarce. This indispensable resource equips physicians, nurses, advanced practice providers, first responders, and rescuers with the essential knowledge and skills to effectively address and prevent injuries and illnesses – no matter where they happen! Brand-new 2-volume format ensures all content is available in print and online to provide you easy access. Face any medical challenge in the wilderness with expert guidance from hundreds of outstanding world experts edited by Dr. Auerbach and 2 new associate editors, Drs.Tracy Cushing and N. Stuart Harris New and expanded chapters with hundreds of new photos and illustrative drawings help increase your visual understanding of the material Acquire the knowledge and skills you need with revised chapters providing expanded discussions of high-altitude medicine, improvisation, technical rescue, telemedicine, ultrasound, and wilderness medicine education Ten new chapters cover Acute High-Altitude Medicine and Pathophysiology; High Altitude and Pre-Existing Medical Conditions; Cycles, Snowmobiles, and other Wilderness Conveyances; Medical Wilderness Adventure Races (MedWAR); Canyoneering and Canyon Medicine; Evidence-Based Wilderness Medicine; National Park Service Medicine; Genomics and Personalized Wilderness Medicine; Forestry; and Earth Sciences 30+ Expert Consult online videos cover survival tips, procedural demonstrations, and detailed explanations of diseases and incidents Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos, and references from the book on a variety of devices

Index Veterinarius

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ISBN 13 :
Total Pages : 1248 pages
Book Rating : 4.:/5 (319 download)

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Download or read book Index Veterinarius written by and published by . This book was released on 2002 with total page 1248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Plotkin's Vaccines,E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323790593
Total Pages : 2574 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Plotkin's Vaccines,E-Book by : Walter A. Orenstein

Download or read book Plotkin's Vaccines,E-Book written by Walter A. Orenstein and published by Elsevier Health Sciences. This book was released on 2022-12-21 with total page 2574 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin’s Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin’s Vaccines is a must-have reference for current, authoritative information in this fast-moving field. Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. Analyzes the cost-benefit and cost-effectiveness of different vaccine options. Helps you clearly visualize concepts and objective data through an abundance of tables and figures.

Canadian Immunization Guide

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ISBN 13 : 9780660193922
Total Pages : 392 pages
Book Rating : 4.1/5 (939 download)

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Book Synopsis Canadian Immunization Guide by : Canada. Comité consultatif national de l'immunisation

Download or read book Canadian Immunization Guide written by Canada. Comité consultatif national de l'immunisation and published by . This book was released on 2006 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.