Enzymes Dependent On Pyridoxal Phosphate And Other Carbonyl Compounds As Cofactors

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Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors

Author : T. Fukui
Publisher : Elsevier
ISBN 13 : 1483287564
Total Pages : 675 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors by : T. Fukui

Download or read book Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors written by T. Fukui and published by Elsevier. This book was released on 2013-10-22 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a summary of the proceedings of the 8th International Symposium on Vitamin B6 and Carbonyl Catalysis, held in Osaka, Japan, 15-19 October 1990. The development of molecular biology and x-ray crystallography techniques have contributed greatly to the knowledge and understanding of PLP-dependent enzymes. The structural, mechanistic and functional aspects of the PLP-dependent enzymes have been studied for over 40 years by many active researchers. Recent evidence indicates that the coenzyme is substituted by the pyruvoyl group which is a reactive carbonyl in some amino acid decarboxylases, and the presence of pyrroloquinoline quinone (PQQ), another carbonyl coenzyme, in other enzymes. The contents of this volume attest to the exciting progress in elucidating structure, mechanism of action, and the function of enzymes dependent on coenzymes containing the carbonyl group.

Nutritional Biochemistry of the Vitamins

Author : David A. Bender
Publisher : Cambridge University Press
ISBN 13 : 1139437739
Total Pages : 514 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Nutritional Biochemistry of the Vitamins by : David A. Bender

Download or read book Nutritional Biochemistry of the Vitamins written by David A. Bender and published by Cambridge University Press. This book was released on 2003-09-18 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative and comprehensive review of our current knowledge of the vitamins, their metabolic functions and the scientific basis for setting recommended intakes for the prevention of deficiency and promotion of optimum health. This publication will be a valuable reference for students and specialists alike in the field of nutritional biochemistry.

Novel Cofactors

Author : Judith P. Klinman
Publisher : Gulf Professional Publishing
ISBN 13 : 9780120342587
Total Pages : 502 pages
Book Rating : 4.3/5 (425 download)

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Book Synopsis Novel Cofactors by : Judith P. Klinman

Download or read book Novel Cofactors written by Judith P. Klinman and published by Gulf Professional Publishing. This book was released on 2001-10-05 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cofactor is a component part of many enzymes and functions by uniting with another molecule in order to become active. The use of cofactors to supplement the native amino acids of a protein is essential to maintain the chemical capabilities necessary for organisms to survive. This volume focuses on the significant advances of the past decade in identifying and describing new cofactors--either small molecules or those derived posttranslationally.

Laboratory Assessment of Vitamin Status

Author : Dominic J. Harrington
Publisher : Academic Press
ISBN 13 : 0128130512
Total Pages : 342 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Laboratory Assessment of Vitamin Status by : Dominic J. Harrington

Download or read book Laboratory Assessment of Vitamin Status written by Dominic J. Harrington and published by Academic Press. This book was released on 2018-11-28 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of 'Best Practice' approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status. - Describes specialist assays in sufficient detail to enable laboratories to replicate what is being performed by expert groups - Provides detailed information that supports laboratories in the setting up of methods for the evaluation of vitamin status - Informs laboratories looking for third party providers of specialist investigations - Provides an essential overview of reference ranges for each vitamin

Biochemistry of Vitamin B6 and PQQ

Author : G. Marino
Publisher : Birkhäuser
ISBN 13 : 303487393X
Total Pages : 324 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Biochemistry of Vitamin B6 and PQQ by : G. Marino

Download or read book Biochemistry of Vitamin B6 and PQQ written by G. Marino and published by Birkhäuser. This book was released on 2012-12-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Intemational Meeting on Vitamin B6 and Carbonyl Catalysis took place on Capri, Italy from 22nd to 27th May 1994 and was organized in conjunction with the 3rd Symposium on PQQ and Quinoproteins. It was an extraordinary occasion for scientists from all over the world to meet and discuss new developments in these overlapping fields. Several sessions were dedicated to the molecular aspects of Vitamin B6 and Quinone dependent enzymes, as well as to the cellular, biomedical and nutritional aspects. The congress was inaugurated by Paolo Fasella in his capacity as General Director of Science, Research and Development of the Commission of the European Communities, with an overview on Intemational Scientific Collaboration. The scientific sessions started with a talk on the History of Vitamin B6 given by David Metzler who at the very last minute presented Esmond Snell's paper adding some personal remarks. Unfortunately, both Esmond Snell and Alton Meister had to unexpectedly cancel the trip to Capri. These proceedings contain the papers presented as oral contributions and a few selected poster presentations. The limited number of pages meant we could not publish many interesting poster presentations, including those selected for the three lively and exciting evening poster discussion sessions called by the organizers "Vino, taralli and ... discussion".

Comprehensive Natural Products III

Author :
Publisher : Elsevier
ISBN 13 : 0081026919
Total Pages : 4266 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Natural Products III by :

Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience

Chemistry of Plant Phosphorus Compounds

Author : Arlen Frank
Publisher : Elsevier
ISBN 13 : 0124072232
Total Pages : 688 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Chemistry of Plant Phosphorus Compounds by : Arlen Frank

Download or read book Chemistry of Plant Phosphorus Compounds written by Arlen Frank and published by Elsevier. This book was released on 2013-06-03 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a high level reference source for scientists engaged in any aspect of plant research - chemistry, biochemistry or physiology - with primary focus on the chemistry of phosphorus-containing compounds that occur naturally in the plant kingdom, and specifically in the higher plants (Plantae). The book is comprehensive with respect to nomenclature, physical properties, and distribution worldwide. There are many tables of actual data on phosphorus compounds occurring in whole plants and parts of plants. The tables provide detailed data that is needed by the food industry, agriculture, etc as many of the phosphorus compounds are common to both plants and animals. Two appendices cover other aspects including changes in phosphorus-containing compounds during germination and their accumulation during growth and senescence. The final sections of the book comprise separate indexes of plants, compounds and authors. - Comprehensive examination of phosphorus compounds found in plants - Extensive tables listing types of compounds and their occurrence in plants including: Nomenclature; Occurrence; Physical Properties; Synthesis; Hydrolysis; Phosphorylation; Extraction; Separation and Analysis - Easy to use indexes of plants, compounds and authors

Introduction to Enzyme and Coenzyme Chemistry

Author : T. D. H. Bugg
Publisher : John Wiley & Sons
ISBN 13 : 1118348990
Total Pages : 310 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Introduction to Enzyme and Coenzyme Chemistry by : T. D. H. Bugg

Download or read book Introduction to Enzyme and Coenzyme Chemistry written by T. D. H. Bugg and published by John Wiley & Sons. This book was released on 2012-05-29 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes are giant macromolecules which catalyse biochemical reactions. They are remarkable in many ways. Their three-dimensional structures are highly complex, yet they are formed by spontaneous folding of a linear polypeptide chain. Their catalytic properties are far more impressive than synthetic catalysts which operate under more extreme conditions. Each enzyme catalyses a single chemical reaction on a particular chemical substrate with very high enantioselectivity and enantiospecificity at rates which approach “catalytic perfection”. Living cells are capable of carrying out a huge repertoire of enzyme-catalysed chemical reactions, some of which have little or no precedent in organic chemistry. The popular textbook Introduction to Enzyme and Coenzyme Chemistry has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function. This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.

Mammalian Alkaline Phosphatases

Author : José Luis Millan
Publisher : John Wiley & Sons
ISBN 13 : 3527607471
Total Pages : 337 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Mammalian Alkaline Phosphatases by : José Luis Millan

Download or read book Mammalian Alkaline Phosphatases written by José Luis Millan and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: * The structure, regulation and expression of the AP genes * The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes * The phenotypic abnormalities of the different AP knockout mice * Our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.

Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition

Author : Richard B. Silverman
Publisher : Elsevier
ISBN 13 : 0080513360
Total Pages : 736 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition by : Richard B. Silverman

Download or read book Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition written by Richard B. Silverman and published by Elsevier. This book was released on 2002-03-07 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. Illustrates the organic mechanism associated with each enzyme-catalyzed reaction Makes the connection between organic reaction mechanisms and enzyme mechanisms Compiles the latest information about molecular mechanisms of enzyme reactions Accompanied by clearly drawn structures, schemes, and figures Includes an extensive bibliography on enzyme mechanisms covering the last 30 years Explains how enzymes can accelerate the rates of chemical reactions with high specificity Provides approaches to the design of inhibitors of enzyme-catalyzed reactions Categorizes the cofactors that are appropriate for catalyzing different classes of reactions Shows how chemical enzyme models are used for mechanistic studies Describes catalytic antibody design and mechanism Includes problem sets and solutions for each chapter Written in an informal and didactic style

Molecular Aspects of Enzyme Catalysis

Author : Toshio Fukui
Publisher : John Wiley & Sons
ISBN 13 : 3527615962
Total Pages : 266 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Molecular Aspects of Enzyme Catalysis by : Toshio Fukui

Download or read book Molecular Aspects of Enzyme Catalysis written by Toshio Fukui and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Der Umfang der Protein-Forschung nimmt rapide zu, die Techniken werden ständig verfeinert, was zu einer Explosion der Informationen auf diesem Gebiet geführt hat. Dieses Buch stellt die neuesten Ergebnisse der aktivsten Forscher auf dem Gebiet der Enzymkatalyse vor. 28 Autoren aus Japan, den USA und Israel geben unentbehrliche Informationen über Enzymstrukturen und Funktionsanalysen. Wertvolle Anregungen für die Neugestaltung wirkungsvoller Biokatalysatoren werden gegeben. Neue Trends und fortgeschrittene Techniken werden eingehend besprochen. Darüber hinaus werden die Strukturen und Funktionen wichtiger Enzyme im Detail dargestellt. Sie schließen ein . Aspartate Aminotransferase . Tryptophan Synthase . Alanine Racemase . Tryptophanase . Superoxid Dismutase . H+-ATPase

Natural Product Biosynthesis

Author : Christopher T. Walsh
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010760
Total Pages : 787 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Natural Product Biosynthesis by : Christopher T. Walsh

Download or read book Natural Product Biosynthesis written by Christopher T. Walsh and published by Royal Society of Chemistry. This book was released on 2017-04-28 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.

Activity-Based Protein Profiling

Author : Benjamin F. Cravatt
Publisher : Springer
ISBN 13 : 3030111431
Total Pages : 417 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Activity-Based Protein Profiling by : Benjamin F. Cravatt

Download or read book Activity-Based Protein Profiling written by Benjamin F. Cravatt and published by Springer. This book was released on 2019-01-25 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions.

Handbook of Vitamins

Author : Robert B. Rucker
Publisher : CRC Press
ISBN 13 : 1420005804
Total Pages : 608 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook of Vitamins by : Robert B. Rucker

Download or read book Handbook of Vitamins written by Robert B. Rucker and published by CRC Press. This book was released on 2007-06-08 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, Handbook of Vitamins highlights the recent research in vitamins and gene expression, vitamin-dependent genes, and vitamin effect on DNA stability. This fourth edition includes new chapters on vitamin-dependent modification of chromatin, analysis of vitamin metabolism using accelerated mass spectrometry, and diet

Progress in Biological Chirality

Author : Gyula Palyi
Publisher : Elsevier
ISBN 13 : 0080474039
Total Pages : 445 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Progress in Biological Chirality by : Gyula Palyi

Download or read book Progress in Biological Chirality written by Gyula Palyi and published by Elsevier. This book was released on 2004-12-13 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following on from Advances in BioChirality, Progress in Biological Chirality provides a unique summary and review of the most recent developments in the field of biochirality. Living organisms use only one enantiomer of chiral molecules in the majority of biologically important processes. The exact origin and mechanisms for this surprising selectivity are not yet known. This book discusses current research aimed at identifying the scientific reasons that may contribute to this phenomenon. Progress in Biological Chirality takes an interdisciplinary approach to this exciting field, covering a wide range of topics, such as, theory, palaeontology and food technology, to name but a few. This book presents findings via a broad spectrum of scientific approaches making it an excellent overview of Biological Chirality, suitable for postgraduate students, practitioners and researchers in the field of chemistry, biochemistry, biology, palaeontology, and food science with an interest in Chirality. - This book contains 32 chapters written by Authors, who are leading authorities in the field - Presents the most recent research taking place in this highly challenging field - Contains both reference material for the specialist and provides an overview for those who are interested in the fundamental problems of biology and chemistry

Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins

Author : Ana J. Iriarte
Publisher : Birkhäuser
ISBN 13 : 3034883978
Total Pages : 371 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins by : Ana J. Iriarte

Download or read book Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins written by Ana J. Iriarte and published by Birkhäuser. This book was released on 2012-12-06 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first international meeting on Vitamin B6 involvement in catalysis took place in 1962, there have been periodic meetings every three or four years. In 1990, scientists studying another cofactor, PQQ, which had already attracted the scientific community's interest for its possible involvement in amino acid decarboxylation and reactions involving amino groups, joined forces with those investigating pyridoxal phosphate-dependent enzymes. Since then, the international PQQ/quinoproteins meetings have been held jointly. In the years following the original meeting 37 years ago in Rome, Italy, the scientific gatherings have taken place in Moscow, Russia (1966); Nagoya, Japan (1967); Leningrad (St. Petersburg), Russia (1974); Toronto, Canada (1979); Athens, Greece (1983); Turku, Finland (1987); Osaka, Japan (1990); and Capri, Italy (1996). For the first time in the history of these symposia, the international meeting was held in the United States, from October 31 through November 5, 1999, in Santa Fe, New Mexico. The scientific program focus shifted significantly beyond the original emphasis on catalysis to aspects such as cellular and genetic regulation of events involving proteins that require pyridoxal phosphate or quinoproteins. The growing awareness of the involvement of these proteins in biotechnology processes and fundamental physiological events, as well as their implication in diseases, was also represented, with emphasis on the molecular basis of these events. The meeting was symposium S278, sponsored by the International Union of Biochemistry and Molecular Biology (IUBMB).

Medicinal Natural Products

Author : Paul M. Dewick
Publisher : John Wiley & Sons
ISBN 13 : 9780471496410
Total Pages : 524 pages
Book Rating : 4.4/5 (964 download)

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Book Synopsis Medicinal Natural Products by : Paul M. Dewick

Download or read book Medicinal Natural Products written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2002-01-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.