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Enzyme Mechanism From Isotope Effects
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Book Synopsis Enzyme Mechanism from Isotope Effects by : Paul F. Cook
Download or read book Enzyme Mechanism from Isotope Effects written by Paul F. Cook and published by CRC Press. This book was released on 1991-09-20 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.
Book Synopsis Isotope Effects on Enzyme-catalyzed Reactions by : William Wallace Cleland
Download or read book Isotope Effects on Enzyme-catalyzed Reactions written by William Wallace Cleland and published by . This book was released on 1977 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Measurement and Analysis of Kinetic Isotope Effects by :
Download or read book Measurement and Analysis of Kinetic Isotope Effects written by and published by Academic Press. This book was released on 2017-09-12 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this comprehensive update include Measurement of enzyme binding isotope effects, Chemical ligation and isotope labeling to locate dynamic effects, Measurement of heavy enzyme isotope effects, Extracting kinetic isotope effects from a global analysis of reaction progress curves, KIE of metabolic flux and enzymes, Solvent and Primary KIE on Flavin Enzymes, and The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD. Readers who are interested in applying or understanding this research will find useful methods currently used for measuring isotope effects on solution and enzyme reactions. Written by pioneers of modern isotope effect research Is the only collection of modern kinetic isotope effect methods currently available
Book Synopsis Determination of Isotope Effects to Elucidate Enzyme Mechanisms by : John Sears Blanchard
Download or read book Determination of Isotope Effects to Elucidate Enzyme Mechanisms written by John Sears Blanchard and published by . This book was released on 1979 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Novel Uses of Isotope Effects to Elucidate Enzyme Reaction Mechanisms by : Jeffrey D. Hermes
Download or read book Novel Uses of Isotope Effects to Elucidate Enzyme Reaction Mechanisms written by Jeffrey D. Hermes and published by . This book was released on 1983 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Use of Isotope Effects as a Probe of Enzyme Reaction Mechanisms by : Paul Martin Karl Weiss
Download or read book The Use of Isotope Effects as a Probe of Enzyme Reaction Mechanisms written by Paul Martin Karl Weiss and published by . This book was released on 1987 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Isotope Effects In Chemistry and Biology by : Amnon Kohen
Download or read book Isotope Effects In Chemistry and Biology written by Amnon Kohen and published by CRC Press. This book was released on 2005-11-01 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of isotope effects has expanded exponentially in the last decade, and researchers are finding isotopes increasingly useful in their studies. Bringing literature on the subject up to date, Isotope Effects in Chemistry and Biology covers current principles, methods, and a broad range of applications of isotope effects in the physical, biolo
Book Synopsis Use of Isotope Effects to Determine Enzymatic and Nonenzymatic Mechanisms by : Mark Alan Rishavy
Download or read book Use of Isotope Effects to Determine Enzymatic and Nonenzymatic Mechanisms written by Mark Alan Rishavy and published by . This book was released on 2000 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Elucidation of Mechanism and Transition State Structure for Enzyme and Non-enzyme Catalyzed Reactions with the Aid of Novel Methods for the Measurement of Oxygen-18 Isotope Effects by : Steven Rosenberg
Download or read book The Elucidation of Mechanism and Transition State Structure for Enzyme and Non-enzyme Catalyzed Reactions with the Aid of Novel Methods for the Measurement of Oxygen-18 Isotope Effects written by Steven Rosenberg and published by . This book was released on 1978 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Enzyme Kinetics and Mechanism by : Paul F. Cook
Download or read book Enzyme Kinetics and Mechanism written by Paul F. Cook and published by Garland Science. This book was released on 2007-03-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzyme Kinetics and Mechanism is a comprehensive textbook on steady-state enzyme kinetics. Organized according to the experimental process, the text covers kinetic mechanism, relative rates of steps along the reaction pathway, and chemical mechanism—including acid-base chemistry and transition state structure. Practical examples taken from the literature demonstrate theory throughout. The book also features numerous general experimental protocols and how-to explanations for interpreting kinetic data. Written in clear, accessible language, the book will enable graduate students well-versed in biochemistry to understand and describe data at the fundamental level. Enzymologists and molecular biologists will find the text a useful reference.
Book Synopsis The Use of Isotope Effects to Determine the Chemical Mechanism of Oxidative Decarboxylases by : Charles Buell Grissom
Download or read book The Use of Isotope Effects to Determine the Chemical Mechanism of Oxidative Decarboxylases written by Charles Buell Grissom and published by . This book was released on 1985 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Determination of the Transition State Structures and Mechanisms of Enzymatic and Nonenzymatic Reactions Through Kinetic Isotope Effects by : Barbara Gerratana
Download or read book Determination of the Transition State Structures and Mechanisms of Enzymatic and Nonenzymatic Reactions Through Kinetic Isotope Effects written by Barbara Gerratana and published by . This book was released on 2001 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Kinetic Isotope Effect Investigation of Enzyme Mechanism in Organic Solvents by : Kenneth A. H. Adams
Download or read book Kinetic Isotope Effect Investigation of Enzyme Mechanism in Organic Solvents written by Kenneth A. H. Adams and published by . This book was released on 1990 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Contemporary Enzyme Kinetics and Mechanism by : Daniel L. Purich
Download or read book Contemporary Enzyme Kinetics and Mechanism written by Daniel L. Purich and published by Academic Press. This book was released on 1983-01-01 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected Methods in Enzymology: Contemporary Enzyme Kinetics and Mechanism provides an introduction to enzyme kinetics and mechanism at an intermediate level. This book covers a variety of topics, including temperature effects in enzyme kinetics, cryoenzymology, substrate inhibition, enol intermediates enzymology, and heavy-atom isotope effects. Organized into 19 chapters, this book begins with an overview of derivation of rate equations as an integral part of the effective usage of kinetics as a tool. This text then examines the practical aspects of initial rate enzyme assay. Other chapters consider the basic procedures used in making decisions concerning kinetic mechanisms from initial-rate data. This book discusses as well the various aspects of both the theoretical background and the applications. The final chapter deals with the importance of achieving proficiency in formulating quantitative relationships describing enzyme behavior. This book is a valuable resource for students and research workers. Enzymologists and chemists will also find this book useful.
Book Synopsis Diary of an Ex-Deuterium Adduct by : David H. Ingbar
Download or read book Diary of an Ex-Deuterium Adduct written by David H. Ingbar and published by . This book was released on 1974 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Enzyme Kinetics and Mechanisms by : Kenneth B. Taylor
Download or read book Enzyme Kinetics and Mechanisms written by Kenneth B. Taylor and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzyme Kinetics and Mechanisms takes the reader through the experimental techniques and the logic by which the mechanisms of enzyme-catalyzed reactions can be elucidated by the results of steady-state kinetics and related experiments. It is meant to make these investigations both satisfying and effective. In distinction to other available descriptions, the descriptions in enzyme Kinetics and Mechanisms are limited to more commonly utilized and useful models and techniques. The logic relating the chemical models to the mathematical models and the logic of relating the mathematical models to data is presented in rather concise text, figures and equations. The development of mathematical models from chemical models is done by a unique algorithm that is both simple and quick, and the same concept are utilized to develop models for the effects of a variety of reaction conditions on the initial velocity. In addition, the various relationships of data, mathematical models and the chemical models is illustrated with examples from the scientific literature.
Book Synopsis Heavy Atom Isotope Effects by : E. Buncel
Download or read book Heavy Atom Isotope Effects written by E. Buncel and published by . This book was released on 1992 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
