Environmental Mutagens

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Networking of Mutagens in Environmental Toxicology

Author : Kavindra Kumar Kesari
Publisher : Springer
ISBN 13 : 3319965115
Total Pages : 189 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Networking of Mutagens in Environmental Toxicology by : Kavindra Kumar Kesari

Download or read book Networking of Mutagens in Environmental Toxicology written by Kavindra Kumar Kesari and published by Springer. This book was released on 2019-05-25 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest environmental issues based on current research objectives. All chapters are fundamentally interlinked and focus on deciphering the networking of mutagens in environmental toxicity and human health. Our changing environment, climate, and lifestyle factors are growing concerns in the 21st century. The existing mutagens, either physical or chemical, are responsible for environmental toxicity. These toxicants are carcinogenic and not limited to naturally occurring chemicals or biologicals, but can also be man-made, such as 'radiation'. The networking of mutagens can have a broad range of effects on both the environment and human health. Accordingly, the respective chapters explore the networking of mutagens in connection with environmental toxicity, and address: 1. Extant types of man-made radiation and their effects on the environment and biological systems2. Heavy metal contaminations: Effects on environmental health3. Networking of environmental pollutants in the air, dust, soil, water, and natural toxins in the environment: Exposure and health4. The molecular interaction of environmental carcinogens with DNA: An oncoinformatics approach5. Fundamentals of nonotoxicity, carcinogenicity, mutagenic and neurotoxicity in environmental health6. The role of antioxidants and medicinal plants in reducing the impacts of disease-causing pollutants A sequel to Perspectives in Environmental Toxicology, this book highlights the latest developments in the field of environmental toxicology. It offers a valuable resource for researchers, scholars and graduate students alike.

Mutagenicity: Assays and Applications

Author : Ashutosh Kumar
Publisher : Academic Press
ISBN 13 : 0128092602
Total Pages : 352 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mutagenicity: Assays and Applications by : Ashutosh Kumar

Download or read book Mutagenicity: Assays and Applications written by Ashutosh Kumar and published by Academic Press. This book was released on 2017-09-26 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns human health and the environment. Chapters focused on specific types of mutagens or testing methods for their detection collectively explore the current state of human and environmental mutagenesis, future perspectives and regulatory needs. The test procedures for measuring mutagenicity, their advantages and limitations are described with practical and procedural detail, along with their presentation and data processing aspects. It is an essential reference covering the breadth and depth of the field of mutagenicity studies and regulation. By providing both important introductory material and practical assays and applications, this book is useful to graduate students, academic and industry researchers and regulators at various stages of their careers, leading to improved risk assessment and regulation. - Presents an up-to-date and in-depth review of the current state of mutagenesis research - Draws upon the combined experience and expertise of an international group of highly respected editors and chapter authors - Provides an introduction to the concept of mutagenesis with particular consideration given to novel chemicals and materials

Mutation, Cancer, and Malformation

Author : Ernest H.Y. Chu
Publisher : Springer Science & Business Media
ISBN 13 : 1461323991
Total Pages : 852 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Mutation, Cancer, and Malformation by : Ernest H.Y. Chu

Download or read book Mutation, Cancer, and Malformation written by Ernest H.Y. Chu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the early 1930s, when I was a graduate student and later a post-doctoral researcher at the National Research Council for the University of Wisconsin at Madison, we had the opportunity to get acquainted with many graduate students from China who were sent to the University for training in modern basic sciences as well as social sciences. The University of Wisconsin continues to graduate a large number of Chinese students. Economic conditions in the 1930s were very precarious for the United States and other parts of the world. Many of us students grew closer together because we were living on similarly tight budgets. As a matter of fact, we subleased a part of our apartment in Madison to some Chinese graduate students. This was a very nice opportunity for us to learn about the scientific and cultural back ground of our Chinese friends. Many of them came from the interior of China and had had very little opportunity to become acquainted with people from a western culture. Living with these students was a very pleasant and educational experience which gave us a good pic ture of the cultural life and educational system of China at that time--an intimate picture that one normally would not see without travelling in that country.

Chemical Consequences

Author : Scott Frickel
Publisher : Rutgers University Press
ISBN 13 : 9780813534138
Total Pages : 220 pages
Book Rating : 4.5/5 (341 download)

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Book Synopsis Chemical Consequences by : Scott Frickel

Download or read book Chemical Consequences written by Scott Frickel and published by Rutgers University Press. This book was released on 2004 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hereis the first historical and sociological account of the formation of an interdisciplinary science known as genetic toxicology, and of the scientists' social movement that created it. After research geneticists discovered that synthetic chemicals were capable of changing the genetic structure of living organisms, scientists began to explore how these chemicals affected gene structure and function. In the late 1960s, a small group of biologists became concerned that chemical mutagens represented a serious and possibly global environmental threat. Genetic toxicology is nurtured as much by public culture as by professional practices, reflecting the interplay of genetics research and environmental politics. Drawing on a wealth of resources, Scott Frickel examines the creation of this field through the lens of social movement theory. He reveals how a committed group of scientist-activists transformed chemical mutagens into environmental problems, mobilized existing research networks, recruited scientists and politicians, secured financial resources, and developed new ways of acquiring knowledge. The result is a book that vividly illustrates how science and activism were interwoven to create a discipline that remains a defining feature of environmental health science.

Molecular Biology of Mutagens and Carcinogens

Author : Beatrice Singer
Publisher : Springer Science & Business Media
ISBN 13 : 1461337720
Total Pages : 352 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Molecular Biology of Mutagens and Carcinogens by : Beatrice Singer

Download or read book Molecular Biology of Mutagens and Carcinogens written by Beatrice Singer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book originated in numerous Gordon Research Conferences and many other meetings of scientists working in chemistry, biophysics, biochemistry, and biology related to mutagenesis and carcinogenesis. It seemed the appro priate time to sit back and summarize the results of several decades of research in laboratories in different countries. We are very grateful to the Rockefeller Foundation for inviting us to formulate and begin writing the book at the Center for International Studies in Bellagio, Italy, where we were Resident Scholars. We are fortunate to have had the assistance of so many colleagues around the world who cheerfully sent original data, figures, and preprints and lis tened patiently to us as we worked out the various conflicting ideas in this fast-moving. field. The names of these scientists are found within the tables, figures, and references. There is one person whose contributions we especially wish to acknowl edge. Professor Heinz Fraenkel-Conrat was present at the inception of this book and throughout the writing encouraged and criticized in apprOximately equal proportion. Finally, his editing and amalgamation of our two styles gave us great comfort. B.S. D.G.

Second International Conference on Environmental Mutagens in Human Populations

Author :
Publisher :
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Second International Conference on Environmental Mutagens in Human Populations by :

Download or read book Second International Conference on Environmental Mutagens in Human Populations written by and published by . This book was released on 1996 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Potential Industrial Carcinogens and Mutagens

Author : L. Fishbein
Publisher : Elsevier
ISBN 13 : 0080874630
Total Pages : 545 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Potential Industrial Carcinogens and Mutagens by : L. Fishbein

Download or read book Potential Industrial Carcinogens and Mutagens written by L. Fishbein and published by Elsevier. This book was released on 2011-08-30 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potential Industrial Carcinogens and Mutagens

Health Effects of Exposure to Low Levels of Ionizing Radiation

Author : National Research Council
Publisher : National Academies
ISBN 13 : 0309039959
Total Pages : 436 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Health Effects of Exposure to Low Levels of Ionizing Radiation by : National Research Council

Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiation written by National Research Council and published by National Academies. This book was released on 1990-02-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.

Concepts and Techniques in Genomics and Proteomics

Author : N Saraswathy
Publisher : Elsevier
ISBN 13 : 1908818050
Total Pages : 271 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis Concepts and Techniques in Genomics and Proteomics by : N Saraswathy

Download or read book Concepts and Techniques in Genomics and Proteomics written by N Saraswathy and published by Elsevier. This book was released on 2011-07-01 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts and techniques in genomics and proteomics covers the important concepts of high-throughput modern techniques used in the genomics and proteomics field. Each technique is explained with its underlying concepts, and simple line diagrams and flow charts are included to aid understanding and memory. A summary of key points precedes each chapter within the book, followed by detailed description in the subsections. Each subsection concludes with suggested relevant original references. - Provides definitions for key concepts - Case studies are included to illustrate ideas - Important points to remember are noted

Mutagenic Effects of Environmental Contaminants

Author : H.E. Sutton
Publisher : Academic Press
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Mutagenic Effects of Environmental Contaminants by : H.E. Sutton

Download or read book Mutagenic Effects of Environmental Contaminants written by H.E. Sutton and published by Academic Press. This book was released on 1972 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mutagenic effects of environmental contaminants ...

Genetic Toxicology Testing

Author : Ray Proudlock
Publisher : Academic Press
ISBN 13 : 0128010061
Total Pages : 458 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Genetic Toxicology Testing by : Ray Proudlock

Download or read book Genetic Toxicology Testing written by Ray Proudlock and published by Academic Press. This book was released on 2016-05-28 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory and test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria. An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. Genetic Toxicology Testing: A Laboratory Manual is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own. - Offers practical and consistent guidance on the most commonly-performed tests and procedures in a genetic toxicology lab - Describes standard genetic toxicology assays, their methodology, reagents, suppliers, and analysis of their results - Includes guidance on general approaches: formulation for in vitro assays, study monitoring, and Good Laboratory Practice (GLP) - Serves as an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own lab

Mutagenicity

Author : John A. Heddle
Publisher : Elsevier
ISBN 13 : 1483271226
Total Pages : 490 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Mutagenicity by : John A. Heddle

Download or read book Mutagenicity written by John A. Heddle and published by Elsevier. This book was released on 2013-10-22 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mutagenicity: New Horizons in Genetic Toxicology provides an overview of the various applications and studies in the field of genetic toxicology and environmental mutagenesis. The book is composed of selected scientific papers written by experts in the field. The text presents topics on naturally occurring mutagens; occupational carcinogen; and evaluation of cooking methods. Experiments on mammalian cell mutation; chromosomal aberrations; and organisms that can be used as environmental monitors of toxicity are discussed as well. Ecologists, environmental and sanitary engineers, toxicologists, and anyone interested in environmental mutagenesis, genetic toxicology, occupational health, or the regulation of toxic substances will find the book a good source of insight.

Chromatin Signaling and Diseases

Author : Olivier Binda
Publisher : Academic Press
ISBN 13 : 012802609X
Total Pages : 468 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Chromatin Signaling and Diseases by : Olivier Binda

Download or read book Chromatin Signaling and Diseases written by Olivier Binda and published by Academic Press. This book was released on 2016-08-06 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatin Signaling and Diseases covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling. After reading this book, clinicians will be more capable of explaining the mechanisms of gene expression regulation to their patients to reassure them about new drug developments that target chromatin signaling mechanisms. For example, several epigenetic drugs that act on chromatin signaling factors are in clinical trials or even approved for usage in cancer treatments, Alzheimer's, and Huntington's diseases. Other epigenetic drugs are in development to regulate various class of chromatin signaling factors. To keep up with this changing landscape, clinicians and doctors will need to stay familiar with genetic advances that translate to clinical practice, such as chromatin signaling. Although sequencing of the human genome was completed over a decade ago and its structure investigated for nearly half a century, molecular mechanisms that regulate gene expression remain largely misunderstood. An emerging concept called chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these, is reviewed in Chromatin Signaling and Diseases. Finally, the impact of gene expression defects associated with malfunctioning chromatin signaling is also explored. - Explains molecular mechanisms that regulate gene expression, which governs everything from embryonic development, growth, and human pathologies associated with aging - Educates clinicians and researchers about chromatin signaling, a molecular mechanism that is changing our understanding of human pathology - Explores the addition and removal of chemical modifications on histones, the proteins that specifically recognize these, and the impact of gene expression defects associated with malfunctioning chromatin signaling - Helps researchers learn about the quickly expanding field of chromatin signaling

Biomarkers in Marine Organisms

Author : Ph. Garrigues
Publisher : Elsevier
ISBN 13 : 008052804X
Total Pages : 573 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Biomarkers in Marine Organisms by : Ph. Garrigues

Download or read book Biomarkers in Marine Organisms written by Ph. Garrigues and published by Elsevier. This book was released on 2001-11-07 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many previous studies and books have been dedicated to fundamental and developmental aspects of biomarkers. The purpose of this book is to provide, through various case studies, an overview of the practical use of biological markers in marine animals to evaluate the health effects of environmental contamination in marine ecosystems. More precisely, the book presents the results obtained during the development and application of biological markers as indicators of exposure/effect to toxic chemicals in marine environments, using diverse sentinel species such as fish, bivalves and crustaceans. An important aspect is also the publication of technical annexes that describe in detail the experimental procedures developed for both chemical and biochemical measurement.

Essentials Of Environmental Toxicology

Author : William Hughes
Publisher : CRC Press
ISBN 13 : 0203362799
Total Pages : 189 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Essentials Of Environmental Toxicology by : William Hughes

Download or read book Essentials Of Environmental Toxicology written by William Hughes and published by CRC Press. This book was released on 2003-09-02 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introductory text addresses the principles and mechanisms of toxicology as applied to environmentally-encountered toxic agents. Each chapter concludes with review questions that may be used for student self-testing and topics covered include dose response, hazards and risk assessment, determination of toxicity, pesticides, metals, plastics, organic solvents, environmental carcinogens, teratogens and mutagens.

Environmental Epigenetics

Author : L. Joseph Su
Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 327 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Environmental Epigenetics by : L. Joseph Su

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Manual on MUTATION BREEDING THIRD EDITION

Author : Food and Agriculture Organization of the United Nations
Publisher : Food & Agriculture Org.
ISBN 13 : 9251305269
Total Pages : 319 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Manual on MUTATION BREEDING THIRD EDITION by : Food and Agriculture Organization of the United Nations

Download or read book Manual on MUTATION BREEDING THIRD EDITION written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2018-10-09 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper provides guidelines for new high-throughput screening methods – both phenotypic and genotypic – to enable the detection of rare mutant traits, and reviews techniques for increasing the efficiency of crop mutation breeding.