Endothelial Biomedicine

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Endothelial Biomedicine

Author : William C. Aird
Publisher : Cambridge University Press
ISBN 13 : 1139465872
Total Pages : 25 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Endothelial Biomedicine by : William C. Aird

Download or read book Endothelial Biomedicine written by William C. Aird and published by Cambridge University Press. This book was released on 2007-09-03 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, the cell layer that forms the inner lining of blood vessels, is a spatially distributed system that extends to all areas of the human body. Clinical and basic research demonstrates that the endothelium plays a crucial role in mediating homeostasis and is involved in virtually every disease, either as a primary determinant of pathophysiology or as a victim of collateral damage. The endothelium has remarkable, though largely untapped, diagnostic and therapeutic potential. This volume bridges the bench-to-bedside gap in endothelial biomedicine, advancing research and development and improving human health. The book is the first to systematically integrate knowledge about the endothelium from different organ-specific disciplines, including neurology, pulmonary, cardiology, gastroenterology, rheumatology, infectious disease, hematology-oncology, nephrology, and dermatology. It's interdisciplinary approach, which draws on expertise from such diverse fields as evolutionary biology, comparative biology, molecular and cell biology, mathematical modeling and complexity theory, translational research, and clinical medicine.

Biology of Endothelial Cells

Author : Eric A. Jaffe
Publisher : Springer Science & Business Media
ISBN 13 : 146132825X
Total Pages : 471 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Biology of Endothelial Cells by : Eric A. Jaffe

Download or read book Biology of Endothelial Cells written by Eric A. Jaffe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: The participation of endothelial cells in various physiologic and pathologic processes has been hypothesized since before the turn of the century. However, until recently, direct evidence for endothelial involvement in these processes has been extremely difficult to obtain due to the inability to study endothelial cell function in vitro. Though the possibility of using cultured endothelial cells to study endothelial cell function in vitro was recognized many years ago, the inability to culture unambiguously identifiable endothelial cells limited investigators in their studies of endothelial function. As a result, the field of endothelial cell biology lay relatively fallow for many years. The development in the early 1970's of routine and easily implemented methods for culturing human endothelial cells and the demonstration that cultured endothelial cells synthesized a physiologically relevant protein, Factor VIII/von Willebrand Factor, quickly changed this state of affairs. Over the following decade the scope of endothelial cell research rapidly widened, spreading in a number of directions. First, methods were developed to culture endothelial cells from a variety of species. Second, methods were developed to culture endothelial cells from different organs and types of blood vessels (arteries, veins, and capillaries) within a single species. Third, and most important, investigators began using cultured endothelial cells as tools to study the potential involvement of endothelial cells in a wide assortment of biologically interesting processes. The net result has been a tremendous increase in our understanding of endothelial cell function.

Endothelial Cell Biology in Health and Disease

Author : M. Simionescu
Publisher : Springer Science & Business Media
ISBN 13 : 1461309379
Total Pages : 460 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Endothelial Cell Biology in Health and Disease by : M. Simionescu

Download or read book Endothelial Cell Biology in Health and Disease written by M. Simionescu and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although blood capillaries were first observed through a flea-lens microscope by Malpighi in 1661,200 more years elapsed before the cellular nature of the vessel wall was conclusively demonstrated. Beginning with the middle of the 19th cen tury, our knowledge of the histological organization of blood vessels has steadily increased. However, the endothelium, which for a long time was considered to be just an inert barrier lining, had been barely explored until three decades ago. Since then, there has been an upsurge of interest in the fine structure and function of endothelial cells. Intense in vivo and in vitro investigations have revealed that the endothelial cell is a key element in a wide variety of normal activities and diseases. A large number of investigators and laboratories have been attracted to endothelial cell research, thus supporting the expansion of the continuously grow ing and diversifying field of endotheliology. The number of articles published annually on this subject has increased from a few score at the beginning of the 1970s to more than a thousand in recent years, and an increasing number of journals, books, societies, and symposia focused primarily on the vascular en dothelium have marked the last decade.

Methods in Endothelial Cell Biology

Author : Hellmut G. Augustin
Publisher : Springer Science & Business Media
ISBN 13 : 3642187250
Total Pages : 383 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Methods in Endothelial Cell Biology by : Hellmut G. Augustin

Download or read book Methods in Endothelial Cell Biology written by Hellmut G. Augustin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes, arthritis, and inflammation. Further, the increasing importance and recognition of the field of vascular biology in general requires in vitro and in vivo techniques in order to address the complex questions. Methods in Endothelial Cell Biology is a comprehensive practical "how-to"-guide summarizing the most relevant established techniques as well as a number of new emerging techniques. Easy-to-follow reliable protocols provide a useful lab bench resource for the experienced researcher and newcomer to the field.

Endothelial Dysfunction and Inflammation

Author : Shauna Dauphinee
Publisher : Springer Science & Business Media
ISBN 13 : 3034601689
Total Pages : 234 pages
Book Rating : 4.0/5 (346 download)

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Book Synopsis Endothelial Dysfunction and Inflammation by : Shauna Dauphinee

Download or read book Endothelial Dysfunction and Inflammation written by Shauna Dauphinee and published by Springer Science & Business Media. This book was released on 2010-09-24 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state. This volume provides an overview of the fields of endothelial dysfunction and inflammation through the discussion of topics ranging from the molecular biology of activated endothelial cells to the endothelium in inflammatory disease and therapeutic approaches targeting endothelial dysfunction. Topics include: Heterogeneity of the endothelium during inflammation, oxidative stress and endothelial dysfunction, biology and regulation of nitric oxide in inflammatory pathologies, endothelial dysfunction in inflammatory diseases, such as diabetes and atherosclerosis and Clinical methods used to assess endothelial function. This book brings together basic and clinical research to assist the reader in bridging connections from bench-to-bedside. Written by expert researchers in the fields of endothelial biology, inflammation research and clinical science, it serves as a useful reference for academic and industrial researchers, clinicians, and trainees in the medical profession.

Cardiovascular Biology

Author : J. F. Stoltz
Publisher : IOS Press
ISBN 13 : 9781586037758
Total Pages : 222 pages
Book Rating : 4.0/5 (377 download)

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Book Synopsis Cardiovascular Biology by : J. F. Stoltz

Download or read book Cardiovascular Biology written by J. F. Stoltz and published by IOS Press. This book was released on 2007 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular endothelial plays a significant role in regulating blood flow, and endothelial cells (EC) have highly active metabolic functions. This volume focuses on Vascular Endothelium, NO and Hypertension and is a continuum of the volumes on Mechanobiology of Cartilage and Chondrocyte.

Endothelial Dynamics in Health and Disease

Author : Jaap Diederik Van Buul
Publisher : Frontiers Media SA
ISBN 13 : 2889663523
Total Pages : 152 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Endothelial Dynamics in Health and Disease by : Jaap Diederik Van Buul

Download or read book Endothelial Dynamics in Health and Disease written by Jaap Diederik Van Buul and published by Frontiers Media SA. This book was released on 2021-01-06 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Mechanisms and Signaling in Endothelial Cell Biology and Vascular Heterogeneity

Author : Bin Ren
Publisher : Frontiers Media SA
ISBN 13 : 2889742520
Total Pages : 332 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Molecular Mechanisms and Signaling in Endothelial Cell Biology and Vascular Heterogeneity by : Bin Ren

Download or read book Molecular Mechanisms and Signaling in Endothelial Cell Biology and Vascular Heterogeneity written by Bin Ren and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanical Forces and the Endothelium

Author : Michael A Gimbrone
Publisher : CRC Press
ISBN 13 : 0203303849
Total Pages : 388 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Mechanical Forces and the Endothelium by : Michael A Gimbrone

Download or read book Mechanical Forces and the Endothelium written by Michael A Gimbrone and published by CRC Press. This book was released on 1999-08-19 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Areas addressed in this excellent text include the overall response of the endothelium to hemodynamic forces, and molecular biology with gene regulation taking a central role.

Endothelial Signaling in Vascular Dysfunction and Disease

Author : Shampa Chatterjee
Publisher : Academic Press
ISBN 13 : 0128163828
Total Pages : 279 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Endothelial Signaling in Vascular Dysfunction and Disease by : Shampa Chatterjee

Download or read book Endothelial Signaling in Vascular Dysfunction and Disease written by Shampa Chatterjee and published by Academic Press. This book was released on 2021-01-20 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside provides a detailed understanding of the endothelium, its activation and their link to some common clinical disorders. In addition, the book covers earlier discoveries, including those from the last and 19th centuries. It is split into five sections that cover the vascular tree as an integrative structure, the endothelium in inflammation, endothelial signaling, activation and toxicity with chemotherapy, radiation induced endothelial dysfunction and vascular disease, and therapies in combating vascular diseases. Each section is discussed with a translational approach in order to make the content truly applicable. This book is a valuable source for basic researchers, clinicians in the fields of Oncology, Cardiovascular Medicine and Radiology, and members of the biomedical field who are conducting studies related to the endothelium and vascular disease. Discusses the most relevant discoveries in endothelial biology and their link to manifestations of clinical disease Presents history and diagrams in each section to highlight the original biological discovery and its link of clinical manifestations of vascular disease Includes recent findings on the relationship between endothelial signaling, chemotherapy and radiation induced endothelial dysfunction

Hemodynamics and Mechanobiology of Endothelium

Author :
Publisher :
ISBN 13 : 9814467243
Total Pages : pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Hemodynamics and Mechanobiology of Endothelium by :

Download or read book Hemodynamics and Mechanobiology of Endothelium written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hemodynamics and Mechanobiology of Endothelium

Author : Tzung K. Hsiai
Publisher : World Scientific
ISBN 13 : 9814280410
Total Pages : 380 pages
Book Rating : 4.8/5 (142 download)

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Book Synopsis Hemodynamics and Mechanobiology of Endothelium by : Tzung K. Hsiai

Download or read book Hemodynamics and Mechanobiology of Endothelium written by Tzung K. Hsiai and published by World Scientific. This book was released on 2010 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress. The investigation of vascular biology and cardiovascular medicine is made possible by the use of tissue engineering, nanotechnology and stem cell research. This is the first textbook to target a wide readership from academia to industry and government agencies in the field of cardiovascular diseases.

Biology of Endothelial Cells

Author : Eric A Jaffe
Publisher :
ISBN 13 : 9781461328261
Total Pages : 476 pages
Book Rating : 4.3/5 (282 download)

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Book Synopsis Biology of Endothelial Cells by : Eric A Jaffe

Download or read book Biology of Endothelial Cells written by Eric A Jaffe and published by . This book was released on 1984-03-31 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Endothelial Dysfunction and Inflammation

Author : Shauna Dauphinee
Publisher : Springer
ISBN 13 : 9783034601672
Total Pages : 234 pages
Book Rating : 4.6/5 (16 download)

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Book Synopsis Endothelial Dysfunction and Inflammation by : Shauna Dauphinee

Download or read book Endothelial Dysfunction and Inflammation written by Shauna Dauphinee and published by Springer. This book was released on 2010-09-16 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state. This volume provides an overview of the fields of endothelial dysfunction and inflammation through the discussion of topics ranging from the molecular biology of activated endothelial cells to the endothelium in inflammatory disease and therapeutic approaches targeting endothelial dysfunction. Topics include: Heterogeneity of the endothelium during inflammation, oxidative stress and endothelial dysfunction, biology and regulation of nitric oxide in inflammatory pathologies, endothelial dysfunction in inflammatory diseases, such as diabetes and atherosclerosis and Clinical methods used to assess endothelial function. This book brings together basic and clinical research to assist the reader in bridging connections from bench-to-bedside. Written by expert researchers in the fields of endothelial biology, inflammation research and clinical science, it serves as a useful reference for academic and industrial researchers, clinicians, and trainees in the medical profession.

Endothelial Luminal Membrane-Glycocalyx

Author : Rafael Rubio
Publisher : Biota Publishing
ISBN 13 : 1615047557
Total Pages : 178 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Endothelial Luminal Membrane-Glycocalyx by : Rafael Rubio

Download or read book Endothelial Luminal Membrane-Glycocalyx written by Rafael Rubio and published by Biota Publishing. This book was released on 2017-11-02 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the structural, biochemical, and diverse functional properties of the endothelial luminal membrane glycocalyx (ELMG), an organelle which constitutes the endothelial cell "membrane." It is intended to provide the newcomer with a broad, basic, and brief perspective of the luminal endothelial vascular membrane, and for the more established investigator, a basic overview and integrated perspective of the "universe" we explore. The endothelium is an assortment of heterogeneous regulatory cells whose cytoplasm and cell membranes are joined, forming functional units. There is a tremendous amount of literature on the endothelial cell, constituting seemingly isolated and distinct fields of encapsulated research. However, the multifunctional properties of some molecules give rise to an overlap of findings, frequently ignored between the different fields. The book is divided into three parts. The first part concentrates on the structure of the ELMG, with emphasis on morphological and biochemical composition. The importance of the chemical composition to the physiological functions of the ELMG, such as sieving properties, pharmacology, and flow sensing, is the focus of the second part of the book. Finally, some of the pathologies associated with ELMG dysfunction are explored in the last section. The aim is to provide basic and well-established knowledge in the various individual fields, identify the current concepts in each area, and discuss their respective strengths and weaknesses (including hidden problems). Finally, the overall goal is to integrate areas where overlap is clearly indicated, bringing them all together to provide the first ever basic, integrative, panoramic bird’s-eye view of the field.

Endothelium and Cardiovascular Diseases

Author : Protasio Lemos Da Luz
Publisher : Academic Press
ISBN 13 : 9780128123485
Total Pages : 0 pages
Book Rating : 4.1/5 (234 download)

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Book Synopsis Endothelium and Cardiovascular Diseases by : Protasio Lemos Da Luz

Download or read book Endothelium and Cardiovascular Diseases written by Protasio Lemos Da Luz and published by Academic Press. This book was released on 2018-01-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians.

Endothelial Cells in Health and Disease

Author : William C. Aird
Publisher : CRC Press
ISBN 13 : 1135534608
Total Pages : 508 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Endothelial Cells in Health and Disease by : William C. Aird

Download or read book Endothelial Cells in Health and Disease written by William C. Aird and published by CRC Press. This book was released on 2005-02-28 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference serves as the first source to gather current data from endothelial cell biologists in various disciplines to summarize recent progress in the field-providing a complete understanding of the endothelium in health and disease and demonstrating its potential as a therapeutic target.