Endometrial Gene Expression

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Endometrial Gene Expression

Author : Joanne Kwak-Kim
Publisher : Springer
ISBN 13 : 9783030285869
Total Pages : 0 pages
Book Rating : 4.2/5 (858 download)

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Book Synopsis Endometrial Gene Expression by : Joanne Kwak-Kim

Download or read book Endometrial Gene Expression written by Joanne Kwak-Kim and published by Springer. This book was released on 2020-11-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endometrium goes through cyclical changes under the influence of hormones, and immune effectors in the endometrium change their populations cyclically as well. Dynamic changes in immune effectors determine endometrial cytokine and chemokine milieus and, consequently, the endometrial immune response. Endometrial immune responses have been shown to be important for trophoblast invasion and early pregnancy. Indeed, dysregulated endometrial inflammatory immune responses are associated with reproductive failures, such as recurrent pregnancy losses, repeated implantation failure, and gynecological diseases with oncogenic potential. Hence, the investigation of endometrial gene expression may predict infertility, gynecological and oncological conditions. This book presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders. It begins with a review of the genetic regulation of urogenital tract formation and molecular mechanism underlying the physiology of menstrual cycle before moving on to the current and emerging technological advances in molecular biology. Endometrial gene expressions of immune inflammatory conditions, viral infection, metabolic and nutritional conditions, and reproductive disorders are then presented in following chapters. Examples of the use and interpretation of gene expression in clinical scenarios including recurrent pregnancy losses, infertility and multiple implantation failures are presented with currently available endometrial gene analysis. Utilizing the latest evidence and clinical guidelines, Endometrial Gene Expression will be a cutting-edge resource for gynecologist, reproductive immunologist, reproductive endocrinologists, obstetrician, maternal fetal medicine specialist and other health care providers in the field of reproductive medicine.

The Endometrium

Author : Stanley R. Glasser
Publisher : CRC Press
ISBN 13 : 0203219031
Total Pages : 1079 pages
Book Rating : 4.2/5 (32 download)

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Book Synopsis The Endometrium by : Stanley R. Glasser

Download or read book The Endometrium written by Stanley R. Glasser and published by CRC Press. This book was released on 2002-05-16 with total page 1079 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Endometrium is devoted to a comprehensive multi-disciplinary account of the uterine endometrium. This book is the first to define the regulatory biological interrelationships between epithelial and stromal cell phenotypes, endothelial cells, extracellular matrix and immunobiological elements. It highlights their relevance to clinical conditions

Molecular Genetics of Endometrial Carcinoma

Author : Lora Hedrick Ellenson
Publisher : Springer
ISBN 13 : 3319431390
Total Pages : 284 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Molecular Genetics of Endometrial Carcinoma by : Lora Hedrick Ellenson

Download or read book Molecular Genetics of Endometrial Carcinoma written by Lora Hedrick Ellenson and published by Springer. This book was released on 2016-12-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text provides a much-needed review of a disease that is currently garnering the interest of molecular biologists, translational scientists, and clinicians. The volume includes emerging developments in the molecular genetics of endometrial carcinoma. In addition to covering the basic genetics of endometrial carcinoma, chapters also cover a wide range of signaling pathways implicated in endometrial carcinoma. A section of the book includes a number of genetically engineered mouse models, which contribute to understanding the role of various genetic alterations in the development and progression of endometrial carcinoma. These models also provide preclinical models for developing effective targeted therapeutic approaches. Endometrial carcinoma is the most common malignancy of the female genital tract in the United States and the number of cases continues to increase around the world. This book is a meant to serve as a resource for a wide range of scientists, from molecular geneticists to signal transduction biologists, as well as to both clinicians and scientists interested in developing targeted therapeutic approaches for women with endometrial carcinoma.

Regulation of Implantation and Establishment of Pregnancy in Mammals

Author : Rodney D. Geisert
Publisher : Springer
ISBN 13 : 3319158562
Total Pages : 271 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Regulation of Implantation and Establishment of Pregnancy in Mammals by : Rodney D. Geisert

Download or read book Regulation of Implantation and Establishment of Pregnancy in Mammals written by Rodney D. Geisert and published by Springer. This book was released on 2015-10-08 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades technological advances in transcriptomics, proteomics, metabolomics, and glycomics along with the ability to selectively knockout genes of interest has greatly advanced our understanding of maternal-conceptus interactions that are essential for the establishment and maintenance of a successful pregnancy. This knowledge provides a foundation from which to build research endeavors to help resolve infertility, embryonic loss and recurrent abortion in humans, captive wild animals and important farm species. The present volume on “Regulation of Implantation and Establishment of Pregnancy in Mammals” brings together current reviews from leading experts to address the diversity of mechanisms by which species establish and maintain pregnancy. Implantation in rodents, dogs, pigs, cattle, sheep, horses, primates, humans and embryonic diapause in wild species are discussed. Reviews will provide current knowledge on the role of endometrial steroid receptors, adhesion factors, cytokines, interferons, steroids, prostaglandins, growth factors and immune cells involved with regulation of conceptus development.

Modern Medical Genetics and Genomics

Author : Israel Gomy
Publisher : BoD – Books on Demand
ISBN 13 : 183968142X
Total Pages : 106 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Modern Medical Genetics and Genomics by : Israel Gomy

Download or read book Modern Medical Genetics and Genomics written by Israel Gomy and published by BoD – Books on Demand. This book was released on 2019-12-18 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of medical genetics and genomics has been constantly revolutionized by new breakthroughs, which bring more knowledge into the etiology and help improve the health care of individuals with either rare or common diseases. Nevertheless, as technologies evolve, novel challenges emerge, both technically and ethically, so they must be prudentially addressed. Among the myriad applications of genomics in medicine, this book depicts a glimpse of the advances achieved that have been leading us to the personalized/precision medicine era.

Epigenetics in Biology and Medicine

Author : Manel Esteller
Publisher : CRC Press
ISBN 13 : 1420007076
Total Pages : 314 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Epigenetics in Biology and Medicine by : Manel Esteller

Download or read book Epigenetics in Biology and Medicine written by Manel Esteller and published by CRC Press. This book was released on 2008-09-17 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anomalous epigenetic patterns touch many areas of study including biomedical, scientific, and industrial. With perspectives from international experts, this resource offers an all-inclusive overview of epigenetics, which bridge DNA information and function by regulating gene expression without modifying the DNA sequence itself. Epigenetics, in its

Placental Bed Disorders

Author : Robert Pijnenborg
Publisher : Cambridge University Press
ISBN 13 : 1139488686
Total Pages : 325 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Placental Bed Disorders by : Robert Pijnenborg

Download or read book Placental Bed Disorders written by Robert Pijnenborg and published by Cambridge University Press. This book was released on 2010-06-03 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now recognized that defective placentation in the human is a cause of many pregnancy complications, such as spontaneous abortion, preterm labor and delivery, pre-eclampsia, intrauterine growth restriction, fetal death and abruptio placenta. These clinical disorders can often have long-term consequences into adulthood, causing cardiovascular disease, obesity and diabetes for the newborn as well as an increased risk of premature death in the mother. This is the first book to be entirely focused on the placental bed, bringing together the results of basic and clinical research in cell biology, immunology, endocrinology, pathology, genetics and imaging to consolidate in a single, informative source for investigators and clinicians. Its core aim is to explore new approaches and improve current clinical practice. This is essential reading for clinicians in obstetric, cardiovascular and reproductive medicine.

Ovum Implantation

Author : Moses Chiam Shelesnyak
Publisher :
ISBN 13 : 9780677132303
Total Pages : 0 pages
Book Rating : 4.1/5 (323 download)

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Book Synopsis Ovum Implantation by : Moses Chiam Shelesnyak

Download or read book Ovum Implantation written by Moses Chiam Shelesnyak and published by . This book was released on 1969 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chronic Pelvic Pain

Author : Richard E. Blackwell
Publisher : Springer Science & Business Media
ISBN 13 : 1461217520
Total Pages : 264 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Chronic Pelvic Pain by : Richard E. Blackwell

Download or read book Chronic Pelvic Pain written by Richard E. Blackwell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clinically oriented, multi-disciplinary approach to the diagnosis, treatment, and management of chronic pelvic pain in women -- one of the most common problems encountered in the practice setting. The editors present this challenging and often vexing subject in a user-friendly, highly illustrated text, with chapters on: physiology of pain; pain associated with endometriosis; pain associated with fibroids; surgical management; the role of office based surgery; the role of the psychiatrist in pain management; pelvic pain of urinary origin; pelvic pain of gastrointestinal origin. Designed to be part of everyday practice, this is a must for all clinicians in obstetrics-gynaecology, as well as for any physician involved in the health care of women.

Uterine Fibroids and Adenomyosis

Author : Norihiro Sugino
Publisher : Springer
ISBN 13 : 9811071675
Total Pages : 173 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Uterine Fibroids and Adenomyosis by : Norihiro Sugino

Download or read book Uterine Fibroids and Adenomyosis written by Norihiro Sugino and published by Springer. This book was released on 2018-06-14 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume elucidates state-of-the-art findings of uterine fibroids and adenomyosis, incorporating expert basic knowledge. Uterine fibroids and adenomyosis are common uterine tumors in reproductive-age women. However, the pathogenesis of the tumors is still poorly understood, and both genetic and environmental factors may be involved in their generation or development. Recent research on the genomics and molecular biology of uterine fibroids and adenomyosis has facilitated a better understanding of the pathogenesis and pathophysiology of these benign tumors. Renowned experts provide detailed discussions of basic research and clinical aspects of uterine fibroids and adenomyosis in this book, from histopathology and molecular pathogenesis to diagnosis and the latest treatment of uterine fibroids, including pregnancy complications of adenomyosis. A great deal of information and a deep understanding of molecular and genetic biology have led to development of more innovative treatments of these tumors. Thus this book benefits not only oncologists, seasoned gynecologists, and obstetricians, but also molecular biologists and other basic researchers who are involved in the treatment of uterine fibroids.

Epigenetic Mechanisms of Gene Regulation

Author : Vincenzo E. A. Russo
Publisher :
ISBN 13 :
Total Pages : 716 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Epigenetic Mechanisms of Gene Regulation by : Vincenzo E. A. Russo

Download or read book Epigenetic Mechanisms of Gene Regulation written by Vincenzo E. A. Russo and published by . This book was released on 1996 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

ICTMI 2017

Author : Balázs Gulyás
Publisher : Springer
ISBN 13 : 9811314772
Total Pages : 220 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis ICTMI 2017 by : Balázs Gulyás

Download or read book ICTMI 2017 written by Balázs Gulyás and published by Springer. This book was released on 2019-02-07 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the latest research presented at the International Conference on Translational Medicine and Imaging (ICTMI) 2017. This event brought together the world’s leading scientists, engineers and clinicians from a wide range of disciplines in the field of medical imaging. Bioimaging has continued to evolve across a wide spectrum of applications from diagnostics and personalized therapy to the mechanistic understanding of biological processes, and as a result there is ever-increasing demand for more robust methods and their integration with clinical and molecular data. This book presents a number of these methods.

The Primate Endometrium

Author : Carlo Bulletti
Publisher :
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.X/5 (1 download)

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Book Synopsis The Primate Endometrium by : Carlo Bulletti

Download or read book The Primate Endometrium written by Carlo Bulletti and published by . This book was released on 1991 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Human Endometrium

Author : Carlo Bulletti
Publisher :
ISBN 13 :
Total Pages : 522 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Human Endometrium by : Carlo Bulletti

Download or read book The Human Endometrium written by Carlo Bulletti and published by . This book was released on 1994 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structural, biochemical and clinical events related to menstruation, implantation, parturition, endometriosis, abnormal uterine bleeding and endometrial cancer are discussed in this comprehensive volume on the biological functions of the endometrium. New topics, such as the biochemical and molecular mechanisms regulating maternal embryonic interaction, are explored, and gynecologic endoscopy and therapeutic tools are discussed. The proceedings of the first conference is also available from the Academy, as volume 622 of The Annals of The New York Academy of Science.

Biomarkers for Endometriosis

Author : Thomas D'Hooghe
Publisher : Springer
ISBN 13 : 3319598562
Total Pages : 271 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Biomarkers for Endometriosis by : Thomas D'Hooghe

Download or read book Biomarkers for Endometriosis written by Thomas D'Hooghe and published by Springer. This book was released on 2017-09-22 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of the diagnostic performance of non- or semi-invasive tests for endometriosis in peripheral blood, endometrium, saliva, peritoneal fluid and urine. The value of existing and emerging systems biology technologies for biomarker development is addressed in several chapters on genetics, microarrays, proteomics and metabolomics. Although tests with high sensitivity and acceptable specificity have been developed, sometimes validated in independent populations and seem promising, more research is needed to translate these data into clinical benefit for patients and coordinate efforts internationally to standarize analysis, reports and operating procedures. The gold standard to diagnose endometriosis is currently through laparoscopic inspection with histological confirmation, a surgical procedure with rare but significant potential risks for the patients. A non-invasive test for endometriosis would be critical for the early detection of endometriosis of symptomatic women with pelvic pain and/or subfertility with normal ultrasound. This would include nearly all cases of minimal-mild endometriosis, some cases of moderate-severe endometriosis without a clearly visible ovarian endometrioma and cases with pelvic adhesions and/or other pelvic pathology, who might benefit from surgery to improve pelvic pain and/or subfertility. Such a test would also be useful in symptomatic women with ultrasound imaging suspicious for endometriosis, since it may be difficult to differentiate an ovarian endometrioma from other ovarian cysts and since the quality of ultrasound imaging is highly variable worldwide.

Development of In Vitro Maturation for Human Oocytes

Author : Ri-Cheng Chian
Publisher : Springer
ISBN 13 : 3319534548
Total Pages : 373 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Development of In Vitro Maturation for Human Oocytes by : Ri-Cheng Chian

Download or read book Development of In Vitro Maturation for Human Oocytes written by Ri-Cheng Chian and published by Springer. This book was released on 2017-05-10 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal reference for infertility specialists and reproductive endocrinologists alike, this comprehensive text discusses current natural and mild approaches to in vitro fertilization (IVF) and the development of in vitro maturation (IVM) as a clinical treatment. It is divided thematically into four sections. Part I presents the basic science of ovarian endocrinology and the mechanism of oocyte maturation, including follicular development and the importance of mitochondrial changes. The differences between natural cycle IVF and stimulated IVF are presented in part II, including the standard ovarian stimulation protocols and their outcomes and the etiology, prevention and management of ovarian hyperstimulation syndrome (OHSS). Minimal and mild stimulation for IVF is discussed in part III, including mild stimulation protocols for oncofertility patients and the new minimally invasive INVO procedure. In vitro maturation as a clinical treatment is the subject of part IV, discussing the methodology of immature oocyte retrieval as well as other laboratory aspects and congenital and obstetrical outcomes of babies born from IVM. Combining expertise from thought leaders around the world, Development of In Vitro Maturation for Human Oocytes will be a go-to resource for infertility researchers and practitioners and reproductive endocrinologists working with infertile couples looking for safer and more cost-effective options for treatment.

Ultrasound Imaging in Reproductive Medicine

Author : Laurel A. Stadtmauer
Publisher : Springer
ISBN 13 : 3030166996
Total Pages : 398 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Ultrasound Imaging in Reproductive Medicine by : Laurel A. Stadtmauer

Download or read book Ultrasound Imaging in Reproductive Medicine written by Laurel A. Stadtmauer and published by Springer. This book was released on 2019-07-19 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in an updated edition, this is the most comprehensive book on modern ultrasound imaging in assisted reproductive technology (ART) and reproductive medicine. Fully revised and expanded, it covers emerging technologies possible with the improvement in ultrasound equipment. 3-D monitoring of ovarian follicles, bidirectional vibrant color and Doppler, and improved 3-D and 4-D imaging of reproductive structures are discussed. MRI-guided ultrasound procedures are covered, and comparisons of 3-D imaging with MRI imaging for uterine anomalies is reviewed with an emphasis on the advantages of 3-D performed in the gynecologist’s office, and as a less expensive modality. The overall approach of the original edition is maintained, starting with ultrasound safety and technique and diagnosis of the ovary, uterus and fallopian tubes (both normal and pathologic), followed by both male and female infertility and ART treatments and procedures. Ultrasound monitoring of follicular development, the endometrium, and as an aid in embryo transfer to maximize IVF success rates are reviewed. Topics new to this edition include updated information on the diagnosis of benign and malignant adnexal masses, 3-D follicle monitoring, and the diagnosis of adenomyosis and endometriosis, including deep inseminated endometriosis. Additionally, the evaluation of endometrial receptivity, the use of contrasts for fallopian tube patency, controversies regarding septate uterus versus arcurate uterus with the use of 3-D ultrasound, and 3-D ultrasound with saline infusion sonogram and early pregnancy ultrasound are all discussed. An excellent resource for reproductive medicine and ART specialists, gynecologists and ultrasonographers alike, Ultrasound Imaging in Reproductive Medicine, Second Edition covers all that clinicians need to know about the role of ultrasound, from the first time a woman comes into the clinic for treatment, including ART, to early pregnancy monitoring. See better, do ART better.