Emerging Drugs And Targets For Multiple Sclerosis

Download Emerging Drugs And Targets For Multiple Sclerosis full books in PDF, epub, and Kindle. Read online Emerging Drugs And Targets For Multiple Sclerosis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Emerging Drugs and Targets for Multiple Sclerosis

Author : Ana Martinez
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014502
Total Pages : 350 pages
Book Rating : 4.7/5 (88 download)

DOWNLOAD NOW!

Book Synopsis Emerging Drugs and Targets for Multiple Sclerosis by : Ana Martinez

Download or read book Emerging Drugs and Targets for Multiple Sclerosis written by Ana Martinez and published by Royal Society of Chemistry. This book was released on 2019-06-28 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis (MS) is a complex disease with a presumed autoimmune aetiology and few current effective treatments. Disease modifying therapies focus on the altering the natural course of relapsing and remitting MS, targeting the inflammatory response. Other targets involve tacking the cause of the disease – demyelination of axons through remyelination therapies. Due to several recent breakthroughs in the understanding of the pathophysiology of MS new targets for remyelination and immunomodulation are rapidly emerging. This book provides a comprehensive overview of drug discovery and development for the molecular basis of the disease, from new targets to drugs currently in clinical development, cellular and animal disease models to biomarkers for diagnosis and assessment in clinical trials. Emerging Drugs and Targets for Multiple Sclerosis is an ideal reference for any student or researcher interested in drug development for neurodegenerative diseases, autoimmune diseases and MS in particular.

Emerging Drugs and Targets for Alzheimer's Disease

Author : Ana Martínez
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (948 download)

DOWNLOAD NOW!

Book Synopsis Emerging Drugs and Targets for Alzheimer's Disease by : Ana Martínez

Download or read book Emerging Drugs and Targets for Alzheimer's Disease written by Ana Martínez and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Emerging Drugs and Targets for Multiple Sclerosis

Author : Ana Martinez
Publisher : Royal Society of Chemistry
ISBN 13 : 1788018060
Total Pages : 350 pages
Book Rating : 4.7/5 (88 download)

DOWNLOAD NOW!

Book Synopsis Emerging Drugs and Targets for Multiple Sclerosis by : Ana Martinez

Download or read book Emerging Drugs and Targets for Multiple Sclerosis written by Ana Martinez and published by Royal Society of Chemistry. This book was released on 2019-06-18 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis (MS) is a complex disease with a presumed autoimmune aetiology and few current effective treatments. Disease modifying therapies focus on the altering the natural course of relapsing and remitting MS, targeting the inflammatory response. Other targets involve tacking the cause of the disease – demyelination of axons through remyelination therapies. Due to several recent breakthroughs in the understanding of the pathophysiology of MS new targets for remyelination and immunomodulation are rapidly emerging. This book provides a comprehensive overview of drug discovery and development for the molecular basis of the disease, from new targets to drugs currently in clinical development, cellular and animal disease models to biomarkers for diagnosis and assessment in clinical trials. Emerging Drugs and Targets for Multiple Sclerosis is an ideal reference for any student or researcher interested in drug development for neurodegenerative diseases, autoimmune diseases and MS in particular.

Emerging Drugs and Targets for Parkinson's Disease

Author : Ana Martinez
Publisher : Royal Society of Chemistry
ISBN 13 : 1849736170
Total Pages : 419 pages
Book Rating : 4.8/5 (497 download)

DOWNLOAD NOW!

Book Synopsis Emerging Drugs and Targets for Parkinson's Disease by : Ana Martinez

Download or read book Emerging Drugs and Targets for Parkinson's Disease written by Ana Martinez and published by Royal Society of Chemistry. This book was released on 2013 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: This exemplary new book reviews some of the most outstanding examples of new drugs currently in pharmaceutical development or new targets under the validation process to try to reach the Parkinson ́s drug market in the next few years as potential disease modifying drugs.

Drug Repurposing

Author : Farid A. Badria
Publisher : BoD – Books on Demand
ISBN 13 : 1839685204
Total Pages : 236 pages
Book Rating : 4.8/5 (396 download)

DOWNLOAD NOW!

Book Synopsis Drug Repurposing by : Farid A. Badria

Download or read book Drug Repurposing written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2020-12-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.

Multiple Sclerosis

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309072859
Total Pages : 457 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Multiple Sclerosis by : Institute of Medicine

Download or read book Multiple Sclerosis written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-10 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Fast Facts: Multiple Sclerosis

Author : Mary Rensel
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1910797235
Total Pages : 146 pages
Book Rating : 4.9/5 (17 download)

DOWNLOAD NOW!

Book Synopsis Fast Facts: Multiple Sclerosis by : Mary Rensel

Download or read book Fast Facts: Multiple Sclerosis written by Mary Rensel and published by Karger Medical and Scientific Publishers. This book was released on 2016-08-29 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last edition of this book, 'no evidence of disease activity' (NEDA) has been proposed as a new treatment target, early data on the first pharmacological treatments for progressive MS have emerged, and the first remyelination trial has shown positive effects on nerve repair. It is with this sense of optimism that the authors of 'Fast Facts: Multiple Sclerosis' have detailed the latest developments for use in clinical practice by all members of the multidisciplinary team, including: • a concise overview of investigations and modern diagnostic criteria • a holistic approach to all signs and symptoms, and proactive relapse management • the latest disease-modifying drugs, including when to treat, choice of drug and risk versus benefit. With case histories that will help to guide treatment decisions, discussion of the special considerations for MS during pregnancy, and in children and the elderly, and a detailed outline of emerging therapies, this book will benefit all healthcare professionals involved in the care of patients with this complex disease.

Autoimmune Neurology

Author :
Publisher : Elsevier
ISBN 13 : 0444634460
Total Pages : 568 pages
Book Rating : 4.4/5 (446 download)

DOWNLOAD NOW!

Book Synopsis Autoimmune Neurology by :

Download or read book Autoimmune Neurology written by and published by Elsevier. This book was released on 2016-03-11 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Reviews on New Drug Targets in Age-Related Disorders

Author : Paul C. Guest
Publisher : Springer Nature
ISBN 13 : 3030550354
Total Pages : 274 pages
Book Rating : 4.0/5 (35 download)

DOWNLOAD NOW!

Book Synopsis Reviews on New Drug Targets in Age-Related Disorders by : Paul C. Guest

Download or read book Reviews on New Drug Targets in Age-Related Disorders written by Paul C. Guest and published by Springer Nature. This book was released on 2021-03-16 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is an inevitable part of life, and is becoming a worldwide social, economic and health problem due to the fact that an increasing proportion of individuals in the advanced age category have a higher probability of developing age-related disorders. New therapeutic approaches are still in need to decrease or slow the effects of such diseases in this aging society. Advances in ‘omic technologies such as genomics, transcriptomics, proteomics and metabolomics have significantly advanced our understanding of diseases in multiple medical areas. It is hoped that emerging hits from these analyses might be prioritized for further screening as potential novel drug targets for increasing the human healthspan in line with the lifespan, which will in turn lead to new therapeutic strategies and drug development projects by the pharmaceutical industry. This new book presents a series of reviews describing studies which have resulted in the identification of potential new drug targets for age-related disorders. Much of this information has come from ‘omic comparisons of healthy and disease states or from testing the effects of potential new therapeutic approaches. Each chapter will be presented in the context of specific chronic diseases or different therapeutic strategies, providing important information on disease mechanisms related to the aging process. This book will be of interest to researchers in the areas of aging and chronic disease, as well as clinical scientists, physicians, and major drug companies. With contributors from Australia, Brazil, Canada, France, Germany, India, Iran, Iraq, South Africa, South Korea, Thailand, Ukraine, United Kingdom, United States of America, Uruguay and Vietnam, this is a timely follow up to Guest’s previous book Reviews on New Drug Targets in Age-Related Disorders.

White Matter Diseases

Author : Massimo Filippi
Publisher : Springer Nature
ISBN 13 : 303038621X
Total Pages : 215 pages
Book Rating : 4.0/5 (33 download)

DOWNLOAD NOW!

Book Synopsis White Matter Diseases by : Massimo Filippi

Download or read book White Matter Diseases written by Massimo Filippi and published by Springer Nature. This book was released on 2020-02-13 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment.

Multiple Sclerosis Therapeutics

Author : Richard Rudick
Publisher : CRC Press
ISBN 13 : 9780415805827
Total Pages : 598 pages
Book Rating : 4.8/5 (58 download)

DOWNLOAD NOW!

Book Synopsis Multiple Sclerosis Therapeutics by : Richard Rudick

Download or read book Multiple Sclerosis Therapeutics written by Richard Rudick and published by CRC Press. This book was released on 1999-09-01 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies and on patient care. The international team of contributors discuss the clinical course of multiple sclerosis, its clinical heterogeneity, the presence of subclinical disease activity which occurs during the early stages of the disease. Multiple sclerosis presents clinical challenges: from unexpected and irregular relapses to profressive deterioration.

Multiple Sclerosis

Author :
Publisher :
ISBN 13 :
Total Pages : 52 pages
Book Rating : 4.3/5 (121 download)

DOWNLOAD NOW!

Book Synopsis Multiple Sclerosis by :

Download or read book Multiple Sclerosis written by and published by . This book was released on 1996 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients

Download Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients PDF Online Free

Author : Paulus Stefan Rommer
Publisher : Frontiers Media SA
ISBN 13 : 288963566X
Total Pages : 253 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!

Book Synopsis Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients by : Paulus Stefan Rommer

Download or read book Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients written by Paulus Stefan Rommer and published by Frontiers Media SA. This book was released on 2020-03-13 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuroimmune Diseases

Author : Hiroshi Mitoma
Publisher : Springer
ISBN 13 : 3030195155
Total Pages : 822 pages
Book Rating : 4.0/5 (31 download)

DOWNLOAD NOW!

Book Synopsis Neuroimmune Diseases by : Hiroshi Mitoma

Download or read book Neuroimmune Diseases written by Hiroshi Mitoma and published by Springer. This book was released on 2019-08-13 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases

Clinical Neuroimmunology

Author : Jack P. Antel
Publisher :
ISBN 13 : 0198510683
Total Pages : 467 pages
Book Rating : 4.1/5 (985 download)

DOWNLOAD NOW!

Book Synopsis Clinical Neuroimmunology by : Jack P. Antel

Download or read book Clinical Neuroimmunology written by Jack P. Antel and published by . This book was released on 2005 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurimmunology is the major reference text in the field, providing broad and comprehensive coverage of the interaction between the nervous and immune systems in both normal and diseased states. Understanding this interaction is fundamental to developing therapeutic approaches todisease and injury of the nervous system that are currently only marginally amenable to therapy. Neuroimmunology is a well-recognised and growing specialty world wide, both at the basic science and clinical level. It is a fast moving field and this is the most up to date text available. Chaptersare dedicated to the role of the immune system in disorders affecting both the central and peripheral nervous systems, including important neurodegenerative diseases (such as multiple sclerosis and HIV-related neural degeneration) which cause life-long disability. Extensive coverage is given to awhole array of immune-directed therapies.The book has a strong international team of well respected, high profile editors and authors. The first edition published to extensive and positive reviews and has established itself as the principal reference source in the field. This second edition summarizes recent advances in clinicalneuroimmunology in a comprehensive and unbiased way.

Autoimmune Disease Models

Author : Irun R. Cohen
Publisher : Academic Press
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Autoimmune Disease Models by : Irun R. Cohen

Download or read book Autoimmune Disease Models written by Irun R. Cohen and published by Academic Press. This book was released on 1994 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.

Interrupted Time Series Analysis

Author : David McDowall
Publisher : Oxford University Press, USA
ISBN 13 : 0190943947
Total Pages : 201 pages
Book Rating : 4.1/5 (99 download)

DOWNLOAD NOW!

Book Synopsis Interrupted Time Series Analysis by : David McDowall

Download or read book Interrupted Time Series Analysis written by David McDowall and published by Oxford University Press, USA. This book was released on 2019 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interrupted Time Series Analysis develops a comprehensive set of models and methods for drawing causal inferences from time series. It provides example analyses of social, behavioral, and biomedical time series to illustrate a general strategy for building AutoRegressive Integrated Moving Average (ARIMA) impact models. Additionally, the book supplements the classic Box-Jenkins-Tiao model-building strategy with recent auxiliary tests for transformation, differencing, and model selection. Not only does the text discuss new developments, including the prospects for widespread adoption of Bayesian hypothesis testing and synthetic control group designs, but it makes optimal use of graphical illustrations in its examples. With forty completed example analyses that demonstrate the implications of model properties, Interrupted Time Series Analysis will be a key inter-disciplinary text in classrooms, workshops, and short-courses for researchers familiar with time series data or cross-sectional regression analysis but limited background in the structure of time series processes and experiments.