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Emcdda Initial Report On The New Psychoactive Substance 1 3 Chlorophenyl 2 Methylamino Propan 1 One 3 Chloromethcathinone 3 Cmc
Download Emcdda Initial Report On The New Psychoactive Substance 1 3 Chlorophenyl 2 Methylamino Propan 1 One 3 Chloromethcathinone 3 Cmc full books in PDF, epub, and Kindle. Read online Emcdda Initial Report On The New Psychoactive Substance 1 3 Chlorophenyl 2 Methylamino Propan 1 One 3 Chloromethcathinone 3 Cmc ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis EMCDDA Initial Report on the New Psychoactive Substance 1-(3-chlorophenyl)-2-(methylamino) Propan-1-one (3-chloromethcathinone, 3-CMC) by :
Download or read book EMCDDA Initial Report on the New Psychoactive Substance 1-(3-chlorophenyl)-2-(methylamino) Propan-1-one (3-chloromethcathinone, 3-CMC) written by and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: 1-(3-Chlorophenyl)-2-(methylamino)propan-1-one (3-chloromethcathinone, 3-CMC) is a synthetic cathinone stimulant. It is a ring-substituted cathinone, which is structurally related to methcathinone and 4-chloromethcathinone (4-CMC). In Europe, 3-CMC is monitored by the EMCDDA as a new psychoactive substance through the European Union Early Warning System (EWS) in accordance with Article 5a of Regulation (EC) No 1920/2006 (as amended). 3-CMC was formally notified as a new psychoactive substance by the EMCDDA on behalf of Sweden on 14 October 2014. The notification was based on the identification of the substance in a police seizure of 0.72 grams of powder made on 22 September 2014 in Norrköping. Since the formal notification, information on 3-CMC has been exchanged between the EMCDDA and the European Union EWS Network (EMCDDA, Europol, Reitox national focal points, and the Commission); the EMA have been kept duly informed. The EMCDDA is currently monitoring 161 synthetic cathinones through the European Union Early Warning System (EU EWS).
Book Synopsis Report on the Risk Assessment of a New Psychoactive Substance 1-(3-chlorophenyl)-2-(methylamino)propan-1-one (3-chloromethcathinone, 3-CMC) in Accordance with Article 5c of Regulation (EC) No 1920/2006 by :
Download or read book Report on the Risk Assessment of a New Psychoactive Substance 1-(3-chlorophenyl)-2-(methylamino)propan-1-one (3-chloromethcathinone, 3-CMC) in Accordance with Article 5c of Regulation (EC) No 1920/2006 written by and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This risk assessment report presents the summary findings and the conclusion of the risk assessment carried out by the Scientific Committee of the EMCDDA on 3-CMC. The report is intended for policymakers and decision-makers in the institutions of the EU. The report has been prepared and drafted in accordance with the requirements of Article 5c of the Regulation as well as the conceptual framework and the procedure set out in the EMCDDA risk assessment operating guidelines. It is written as a stand-alone document, which presents a summary of the information considered during the detailed assessment of the scientific and law enforcement information available at this time. The conclusion section of the report summarises the main issues addressed and reflects the opinions held by the members of the Scientific Committee. A list of the information resources considered by the Scientific Committee, including a detailed technical report on 3-CMC prepared by the EMCDDA (Annex 1), is provided below.
Book Synopsis EMCDDA Initial Report on the New Psychoactive Substance 2-(methylamino)-1-(3-methylphenyl) Propan-1-one (3-methylmethcathinone, 3-MMC) by :
Download or read book EMCDDA Initial Report on the New Psychoactive Substance 2-(methylamino)-1-(3-methylphenyl) Propan-1-one (3-methylmethcathinone, 3-MMC) written by and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: 2-(Methylamino)-1-(3-methylphenyl)propan-1-on (3-methylmethcathinone, 3-MMC) is a synthetic cathinone stimulant. It is a ring-substituted cathinone, which is structurally related to methcathinone and 4-methylmethcathinone (mephedrone). In Europe, 3-MMC is monitored by the EMCDDA as a new psychoactive substance through the European Union Early Warning System (EWS) in accordance with Article 5a of Regulation (EC) No 1920/2006 (as amended)). 3-MMC was formally notified as a new psychoactive substance) by the EMCDDA on behalf of Sweden on 5 September 2012. The notification was based on the identification of the substance in a customs seizure of 51.1 grams of powder made on 27 June 2012 in Gothenburg. Since the formal notification, information on 3-MMC has been exchanged between the EMCDDA and the European Union EWS Network (EMCDDA, Europol, Reitox national focal points, and the Commission); the EMA have been kept duly informed. Based on signals suggesting increased availability and harms related to 3-MMC in some parts of Europe, on 2 March 2021, the EMCDDA added 3-MMC to the list of new psychoactive substances under intensive monitoring (8) and requested that the Network expedite reporting of any event involving 3-MMC to the EMCDDA until further notice. The EMCDDA is currently monitoring 161 synthetic cathinones through the European Union Early Warning System (EU EWS).
Book Synopsis The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology by : Simona Pichini
Download or read book The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology written by Simona Pichini and published by Frontiers Media SA. This book was released on 2019-08-19 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Synthetic Opioids (NSOs), most of which are illegally produced and sold for recreational use, are posing a serious threat to the health of consumers. Due to the low cost of materials and equipment required for clandestine laboratories production with respect to the production cost of heroin, NSOs are climbing the illegal street and web drug market. Several of these drugs have been involved in a recent rise in acute intoxications and overdose deaths. Since NSOs offer enormous profit potential, and there is strong demand for their use, these drugs are being trafficked by organized crime and present major challenges for medical professionals facing intoxications and fatalities, law enforcement agencies fighting against their diffusion and policymakers trying to restrain the use and abuse of NSOs. This Research Topic aimed to fill the gap on current knowledge on pharmacology and toxicology, health risks for adult and newborns of NSOs covering both basic scientific as well as epidemiological and clinical aspects. 3 reviews, 3 mini-reviews, 1 original article, 2 case reports and 1 opinion are here presented.
Book Synopsis The SAGE Handbook of Drug & Alcohol Studies by : Torsten Kolind
Download or read book The SAGE Handbook of Drug & Alcohol Studies written by Torsten Kolind and published by SAGE. This book was released on 2016-10-20 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from leading international academics across the social sciences, this accessible handbook takes a critical look at the key theories, disciplinary approaches, contemporary issues and debates in the field. · Part I Central Social Science Theories Drug and Alcohol Studies · Part II Pillars in Social Science Drug and Alcohol Studies · Part III Controversies and New Approaches in Social Science Drug and Alcohol Studies This Handbook is an excellent reference text for the growing number of academics, students, scientists and practitioners in the drug and alcohol studies community.
Book Synopsis Handbook of Novel Psychoactive Substances by : Ornella Corazza
Download or read book Handbook of Novel Psychoactive Substances written by Ornella Corazza and published by Routledge. This book was released on 2018-10-10 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Novel Psychoactive Substances (NPS) provides a comprehensive overview of the challenges that clinicians face when dealing with NPS and discusses how the profile of patients and their socio-demographic characteristics frame the serious public health concern that NPS pose. It presents various clinical cases, as well as detailed accounts of symptoms, psychopathology, toxicity, and overall clinical management that NPS require. This handbook brings together a unique collection of chapters written by leading experts in the field, who have felt the need to share their knowledge and experience to improve the clinical practice on NPS and the wellbeing of their patients.
Book Synopsis Reflections on the Concept of Coherency for a Policy on Psychoactive Substances and Beyond by : Richard Muscat
Download or read book Reflections on the Concept of Coherency for a Policy on Psychoactive Substances and Beyond written by Richard Muscat and published by . This book was released on 2012 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: How are the problems associated with different psychoactive substances, illicit drugs, alcohol and tobacco described? How is the nature of the "problem" shaped by research evidence, media coverage, cultural mores and social, economic and political considerations? To what extent does policy reflect a consistent approach to different psychoactive substances? What objectives do policies on drugs, alcohol and tobacco pursue? Do the structures in place support the co-ordination and/or integration of these policies? The issue of psychoactive substance policies (and beyond) is currently at the forefront of policy making in a number of countries, including those participating in this study, together with the issue of how such a policy may be implemented in a coherent manner. Continuing the work carried out in two previous publications, From a policy on illegal drugs to a policy on psychoactive substances (2008) and Towards an integrated policy on psychoactive substances: a theoretical and empirical analysis (2010), this work attempts to put into perspective the salient points of what may be termed a coherent policy on psychoactive substances and beyond. It proposes six indicators, around which the concept of coherency is articulated: conceptualisation, policy context, legislative and regulatory framework, strategic framework, responses/interventions, and structures and resources. The results of this study may be a surprise to some in the field, and tie in with broader efforts by the European Union and the Organisation for Economic Co-operation and Development in the sphere of policy coherence for development. The Council of Europe has 47 member states, covering virtually the entire continent of Europe. It seeks to develop common democratic and legal principles based on the European Convention on Human Rights and other reference texts on the protection of individuals. Ever since it was founded in 1949, in the aftermath of the Second World War, the Council of Europe has symbolised reconciliation. Book jacket.
Book Synopsis Synthetic Cathinones by : Jolanta B. Zawilska
Download or read book Synthetic Cathinones written by Jolanta B. Zawilska and published by Springer. This book was released on 2018-04-16 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.
Book Synopsis Neuropharmacology of New Psychoactive Substances (NPS) by : Michael H. Baumann
Download or read book Neuropharmacology of New Psychoactive Substances (NPS) written by Michael H. Baumann and published by Springer. This book was released on 2017-04-13 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designer drugs, or new psychoactive substances (NPS), are synthetic chemicals that mimic the effects of classic drugs of abuse. There has been an alarming worldwide increase in the abuse of NPS in recent years. NPS are cheap, easy to obtain, and often legally available. In this volume, leading experts summarize the latest studies regarding the molecular mechanisms of action, behavioral effects, and adverse consequences of popular NPS. Specific chapters clarify the differences between various types of NPS, namely: stimulants, cannabinoids and hallucinogens. Thus, this volume broadens our understanding of NPS and provides insight into the rapidly evolving “new drug” phenomenon.
Book Synopsis Animal Models of Drug Addiction by : Mary C. Olmstead
Download or read book Animal Models of Drug Addiction written by Mary C. Olmstead and published by Humana Press. This book was released on 2010-12-10 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.
Book Synopsis Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors by :
Download or read book Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors written by and published by Academic Press. This book was released on 2010-11-20 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 95 of International Review of Neurobiology focuses on Catechol-O-methyltransferase inhibition, and its clinical application in relation to Parkinson's disease. Chapters cover COMT gene and proteins, L-dopa treatment in Parkinson's disease, the latest research on COMT inhibitors and their clinical applications, as well as future prospects for their use. - Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors - Preclinical models in COMT inhibitor devlopment - Transgenic COMT mice – latest information summarized - Chemistry of COMT inhibitors and their design with molecular modelling - COMT gene and its regulation and relation to dopamine related diseases - Role of cofactor SAM regulation in relation to homocysteine - Nonclinical and clinical safety of COMT inhibitors summarized - Future prospects of COMT inhibitors in Parkinson's disease
Book Synopsis Therapeutic Communities for Treating Addictions in Europe by : Wouter Vanderplasschen
Download or read book Therapeutic Communities for Treating Addictions in Europe written by Wouter Vanderplasschen and published by . This book was released on 2014 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biological Research on Addiction by :
Download or read book Biological Research on Addiction written by and published by Academic Press. This book was released on 2013-05-17 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual's susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of three volumes comprising the 2,500-page series, Comprehensive Addictive Behaviors and Disorders. This series provides the most complete collection of current knowledge on addictive behaviors and disorders to date. In short, it is the definitive reference work on addictions. - Each article provides glossary, full references, suggested readings, and a list of web resources - Edited and authored by the leaders in the field around the globe – the broadest, most expert coverage available - Discusses the genetic basis of addiction - Covers basic science research from a variety of animal studies
Book Synopsis Cannabis Legislation in Europe by : Brendan Hughes
Download or read book Cannabis Legislation in Europe written by Brendan Hughes and published by . This book was released on 2018 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: "At a time of increased debate on the laws controlling the use of cannabis in the European Union, this report answers some of the questions most often asked about cannabis legislation. Using a question and answer format, basic definitions and the obligations of countries under international law are set out in a section on ‘What is cannabis and what are countries’ obligations to control it?‘ Two following sections examine the links and disparities between the content of the laws and their guidelines on the one hand and the actual implementation of the laws on the other. The final question and answer section considers whether changes in law have affected cannabis use and how much public support for legal change exists, as it looks at the future direction of cannabis legislation in Europe." -- Provided by publisher.
Book Synopsis Animal Models of Drug Addiction by : Alan A. Boulton
Download or read book Animal Models of Drug Addiction written by Alan A. Boulton and published by Humana Press. This book was released on 1992-10-23 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: to the Animal Models Volumes This volume describes animal models of drug addiction. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface in order to indicate why we think further research using animals is necessary. Animals should only be used when suitable alternatives are not available, and humans can only be experimented upon in severely proscribed circumstances. Alternative procedures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo p- cesses. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, the research is not ethical and should not be carried out. It is imperative that each individual researcher examine his/ her own research from a critical moral standpoint before eng- ing in it, and take into consideration the animals’ welfare as well as the anticipated gains. Furthermore, once a decision to p- ceed with research is made, it is the researcher’s responsibility to ensure that the animals’ welfare is of prime concern in terms of appropriate housing, feeding, and maximum reduction of any uncomfortable or distressing effects of the experimental conditions.
