RNA Polymerases as Molecular Motors

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Publisher : Royal Society of Chemistry
ISBN 13 : 0854041346
Total Pages : 353 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis RNA Polymerases as Molecular Motors by : Henri C. Buc

Download or read book RNA Polymerases as Molecular Motors written by Henri C. Buc and published by Royal Society of Chemistry. This book was released on 2009-04-16 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by expert scientists in the field, analyses how these diverse fields of research interact on a specific example - RNA polymerase. The book concentrates on RNA polymerases because they play a central role among all the other machines operating in the cell and are the target of a wide range of regulatory mechanisms. They have also been the subject of spectacular advances in their structural understanding in recent years, as testified by the attribution of the Nobel prize in chemistry in 2006 to Roger Kornberg. The book focuses on two aspects of the transcription cycle that have been more intensively studied thanks to this increased scientific cooperation - the recognition of the promoter by the enzyme, and the achievement of consecutive translocation steps during elongation of the RNA product. Each of these two topics is introduced by an overview, and is then presented by worldwide experts in the field, taking the viewpoint of their specialty. The overview chapters focus on the mechanism-structure interface and the structure-machine interface while the individual chapters within each section concentrate more specifically on particular processes-kinetic analysis, single-molecule spectroscopy, and termination of transcription, amongst others. Specific attention has been paid to the newcomers in the field, with careful descriptions of new emerging techniques and the constitution of an atlas of three-dimensional pictures of the enzymes involved.

Current Topics in Microbiology and Immunology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642670873
Total Pages : 161 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Current Topics in Microbiology and Immunology by :

Download or read book Current Topics in Microbiology and Immunology written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structure/function Analysis of the Two Largest Subunits of Escherichia Coli RNA Polymerase

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Author :
Publisher :
ISBN 13 :
Total Pages : 496 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Structure/function Analysis of the Two Largest Subunits of Escherichia Coli RNA Polymerase by : Laura Magdolna Heisler

Download or read book Structure/function Analysis of the Two Largest Subunits of Escherichia Coli RNA Polymerase written by Laura Magdolna Heisler and published by . This book was released on 1994 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Genetics of Mycobacteria

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Publisher : John Wiley & Sons
ISBN 13 : 1555818846
Total Pages : 832 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Molecular Genetics of Mycobacteria by : Graham F. Hatfull

Download or read book Molecular Genetics of Mycobacteria written by Graham F. Hatfull and published by John Wiley & Sons. This book was released on 2020-08-06 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive collection of perspectives by experts in mycobacterial molecular biology Mycobacterium tuberculosis causes one in four avoidable deaths in the developing world and kills more adults than malaria, AIDS, and all tropical diseases combined. Tuberculosis was named a global health emergency by the World Health Organization, a distinction no other disease has received. Although the study of mycobacterial genetics has expanded dramatically, with new investigations into mycobacterial growth, replication, metabolism, physiology, drug susceptibility, and virulence, most of the problems in tuberculosis control that existed in 2000 remain today. Advances in our understanding of mycobacterial genetics have been reflected in exciting recent developments. New diagnostic approaches can identify drug resistance within a few hours, promising new drugs are progressing through the pipeline and into the clinic, and a range of newly developed vaccines are being evaluated. It is an exciting time as the fruits of 30 years of intensive genetic investigation are finally beginning to emerge. Written by leading experts in the field, Molecular Genetics of Mycobacteria, Second Edition, Discusses key areas of current research in mycobacterial genetics Explains the genetics of the physiology, metabolism, and drug sensitivities of M. tuberculosis Presents genetic approaches for manipulating M. tuberculosis This book is an invaluable resource for anyone interested in the molecular genetics and molecular biology of mycobacteria.

Research Awards Index

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Author :
Publisher :
ISBN 13 :
Total Pages : 742 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Studies on the Structure and Function of the [sigma]70 Subunit of Escherichia Coli RNA Polymerase

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Publisher :
ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Genetic Studies on the Structure and Function of the [sigma]70 Subunit of Escherichia Coli RNA Polymerase by : James Chi-Min Hu

Download or read book Genetic Studies on the Structure and Function of the [sigma]70 Subunit of Escherichia Coli RNA Polymerase written by James Chi-Min Hu and published by . This book was released on 1987 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Control of Ribosome Synthesis

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Publisher :
ISBN 13 :
Total Pages : 502 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Control of Ribosome Synthesis by : Niels Ole Kjeldgaard

Download or read book Control of Ribosome Synthesis written by Niels Ole Kjeldgaard and published by . This book was released on 1976 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Inhibitors Tools in Cell Research

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Publisher : Springer Science & Business Media
ISBN 13 : 3642461581
Total Pages : 424 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Inhibitors Tools in Cell Research by : Theodor Bücher

Download or read book Inhibitors Tools in Cell Research written by Theodor Bücher and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope of the 20th Mosbach Colloquium may be best illustrated by the following notes sent to the speakers when the colloquium was organized. "1) The application of inhibitors in cell biology has led to decisive insight into the organisation of cellular units. The subject should be treated against a background of current aspects of cell biology. In some areas of research, a fairly complete picture of the functions and cooperative interactions of the units has already emerged. We will discuss mainly these areas. 2) At this colloquium we want to contribute illustrations of the useful application of inhibitors to biological problems. Due to limited knowledge, inhibitors are sometimes incorrectly employed. This applies both to the planning of investigations and to the con· clusions drawn ("use of inhibitors by uninhibited workers"). 3) Inhibitors themselves are interesting substances and their mechanisms of action constitute fascinating problems." The colloquium has been subdivided into five sections. The known chemical structures of the inhibitors discussed are given in an Appendix. We gratefully appreciate the cooperation of the speakers. To a great extent, they managed the coordination of contributions to each of the five subdivisions. We regret that no contributors from Eastern Europe were able to participate.

Human Herpesviruses

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Publisher : Cambridge University Press
ISBN 13 : 1139461648
Total Pages : 1325 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Human Herpesviruses by : Ann Arvin

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Enzymes of Nucleic Acid Synthesis and Modification

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Publisher : CRC Press
ISBN 13 : 1351080318
Total Pages : 203 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Enzymes of Nucleic Acid Synthesis and Modification by : Samson T. Jacob

Download or read book Enzymes of Nucleic Acid Synthesis and Modification written by Samson T. Jacob and published by CRC Press. This book was released on 2018-01-18 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First volume gives an overview of the enzymes involved in DNA synthesis and modification; the second volume deals with the RNA-enzymes. Although the major emphasis of the book is on eukaryotic enzymes, a separate chapter dealing with prokaryotic DNA repair enzymes has been included to discuss the major advances in this field in recent years. There are two separate chapters on RNA polymerases to provide a comprehensive coverage of the enzymes from lower eukaryotes, plants and higher eukaryotes.

EBOOK: Molecular Biology

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Publisher : McGraw Hill
ISBN 13 : 007714497X
Total Pages : 914 pages
Book Rating : 4.0/5 (771 download)

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Book Synopsis EBOOK: Molecular Biology by : Robert Weaver

Download or read book EBOOK: Molecular Biology written by Robert Weaver and published by McGraw Hill. This book was released on 2011-03-16 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology, 4/e by Robert Weaver, is designed for an introductory course in molecular biology. Molecular Biology 5/e focuses on the fundamental concepts of molecular biology emphasizing experimentation. In particular author, Rob Weaver, focuses on the study of genes and their activities at the molecular level. Through the combination of excellent illustrations and clear, succinct writing students are presented fundamental molecular biology concepts.

Mechanism of Action of Antimicrobial and Antitumor Agents

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Publisher : Springer Science & Business Media
ISBN 13 : 3642463045
Total Pages : 752 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Mechanism of Action of Antimicrobial and Antitumor Agents by : J. F. Snell

Download or read book Mechanism of Action of Antimicrobial and Antitumor Agents written by J. F. Snell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the third in the series devoted to Antibiotics initiated by Springer Verlag in 1967. The first two volumes were devoted to the Mode of Action of Antibiotics and Biogenesis, respectively and were received graciously. During the intervening years these two works have been used often by research workers and students alike and have been quoted extensively. Although a number of other excellent treatises on antibiotics have appeared, the Springer series has set a standard for thoroughness and quality that meets the need of the scientific community. It is against this background that the present Editors set about the preparation of a third volume in the Series on Antibiotics. Since the appearance of Volume I, also dealing with Mechanism of Action, tremendous strides have been made in the depth and breadth of our knowledge of molecular biology, microbial chemistry and molecular pharmacology and of their direct application to studies on the mode of action of drugs. The field of molecular biology itself was in its relative infancy during the preceding decade and the unique role played by many anti biotics in the development of our understanding of nucleic acid synthesis and function and its relationship to protein synthesis and cell physiology has led rapidly to a very precise, understanding of how many of these same antibiotics inhibit susceptible cells.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structure and Function of Genetic Elements

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Publisher :
ISBN 13 :
Total Pages : 202 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Structure and Function of Genetic Elements by : Brookhaven National Laboratory

Download or read book Structure and Function of Genetic Elements written by Brookhaven National Laboratory and published by . This book was released on 1959 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Grants Index

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Publisher :
ISBN 13 :
Total Pages : 1116 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants

Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1974 with total page 1116 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RNA Polymerase

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Publisher :
ISBN 13 :
Total Pages : 920 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis RNA Polymerase by : Richard Losick

Download or read book RNA Polymerase written by Richard Losick and published by . This book was released on 1976 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on reports presented at the 1975 Cold Spring Harbor meeting on RNA polymerase.

Biomedical Index to PHS-supported Research

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Publisher :
ISBN 13 :
Total Pages : 1104 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biomedical Index to PHS-supported Research by :

Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1991 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: