Elements Of Synthesis Planning

Download Elements Of Synthesis Planning full books in PDF, epub, and Kindle. Read online Elements Of Synthesis Planning ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Elements of Synthesis Planning

Author : R. W. Hoffmann
Publisher : Springer Science & Business Media
ISBN 13 : 3540792201
Total Pages : 227 pages
Book Rating : 4.5/5 (47 download)

DOWNLOAD NOW!

Book Synopsis Elements of Synthesis Planning by : R. W. Hoffmann

Download or read book Elements of Synthesis Planning written by R. W. Hoffmann and published by Springer Science & Business Media. This book was released on 2009-01-07 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis is at the core of organic chemistry. In order for compounds to be studied—be it as drugs, materials, or because of their physical properties— they have to be prepared, often in multistep synthetic sequences. Thus, the target compound is at the outset of synthesis planning. Synthesis involves creating the target compound from smaller, readily available building blocks. Immediately, questions arise: From which bui- ing blocks? In which sequence? By which reactions? Nature creates many highly complex “natural products” via reaction cascades, in which an asso- ment of starting compounds present within the cell is transformed by speci c (for each target structure) combinations of modular enzymes in speci c - quences into the target compounds [1, 2]. To mimic this ef ciency is the dream of an ideal synthesis [2]. However, we are at present so far from - alising such a “one-pot” operation that actual synthesis has to be achieved via a sequence of individual discrete steps. Thus, we are left with the task of planning each synthesis individually in an optimal fashion. Synthesis planning must be conducted with regard for certain speci - tions, some of which are due to the structure of the target molecule, and some of which relate to external parameters such as costs, environmental compatibility, or novelty. We will not consider these external aspects in this context. Planning of a synthesis is based on a pool of information regarding chemical reactions that can be executed reliably and in high chemical yield.

The logic of chemical synthesis

Author : E.J. Corey
Publisher : Рипол Классик
ISBN 13 : 5885010811
Total Pages : 447 pages
Book Rating : 4.8/5 (85 download)

DOWNLOAD NOW!

Book Synopsis The logic of chemical synthesis by : E.J. Corey

Download or read book The logic of chemical synthesis written by E.J. Corey and published by Рипол Классик. This book was released on 1991 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Beyond the Molecular Frontier

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309168392
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Beyond the Molecular Frontier by : National Research Council

Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Organic Synthesis

Author : Michael Smith
Publisher : Academic Press
ISBN 13 : 0128008075
Total Pages : 1108 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Organic Synthesis by : Michael Smith

Download or read book Organic Synthesis written by Michael Smith and published by Academic Press. This book was released on 2016-11-22 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. A full Solutions Manual is also available online for qualified instructors, to support teaching. Winner, 2018 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association Fully revised and updated throughout, and organized into 19 chapters for a more cogent and versatile presentation of concepts Includes reaction examples taken from literature research reported between 2010-2015 Features new full-color art and new chapter content on process chemistry and green organic chemistry Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Solutions Manual for qualified course instructors

Flow Chemistry Guided by Computer-aided Synthesis Planning

Author : Christopher Paul Breen
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)

DOWNLOAD NOW!

Book Synopsis Flow Chemistry Guided by Computer-aided Synthesis Planning by : Christopher Paul Breen

Download or read book Flow Chemistry Guided by Computer-aided Synthesis Planning written by Christopher Paul Breen and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Portions of this thesis have been reprinted, adapted, or both, with permission from their respective publishers.

Organic Synthesis

Author : Paul Wyatt
Publisher : John Wiley & Sons
ISBN 13 : 1118681444
Total Pages : 55 pages
Book Rating : 4.1/5 (186 download)

DOWNLOAD NOW!

Book Synopsis Organic Synthesis by : Paul Wyatt

Download or read book Organic Synthesis written by Paul Wyatt and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. * A comprehensive, practical account of the key concepts involved in synthesising compounds * Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations * Focuses on reactions that really work rather than those with limited application * Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

Structure-based Synthesis Planning

Author : Kai Sommer
Publisher :
ISBN 13 :
Total Pages : 231 pages
Book Rating : 4.:/5 (113 download)

DOWNLOAD NOW!

Book Synopsis Structure-based Synthesis Planning by : Kai Sommer

Download or read book Structure-based Synthesis Planning written by Kai Sommer and published by . This book was released on 2019 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Le Corbusier

Author : Stanislaus von Moos
Publisher : 010 Publishers
ISBN 13 : 9064506426
Total Pages : 370 pages
Book Rating : 4.0/5 (645 download)

DOWNLOAD NOW!

Book Synopsis Le Corbusier by : Stanislaus von Moos

Download or read book Le Corbusier written by Stanislaus von Moos and published by 010 Publishers. This book was released on 2009 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in Germany in 1968, this first comprehensive and critical survey of Le Corbusier's life and work soon became the standard text on the architect and polymath. French, Spanish, English, Japanese and Korean editions followed, but the book has now been out of print for almost two decades. In the meantime, Le Corbusier's archives in Paris have become available for research, resulting in an avalanche of scholarship. Von Moos' critical take and the basic criteria by which the subject is organized and historicized remain surprisingly pertinent in the context of this recent jungle of Corbusier studies. This new, completely revised edition is based on the 1979 version published in English by the MIT Press but offers a substantially updated body of illustrations. Each of the seven chapters is supplemented by a critical survey of recent scholarship on the respective issues. An updated edition of this acclaimed book, an essential read for students of architecture and architectural history.

Analysis, Synthesis and Design of Chemical Processes

Author : Richard Turton
Publisher : Pearson Education
ISBN 13 : 0132459183
Total Pages : 1562 pages
Book Rating : 4.1/5 (324 download)

DOWNLOAD NOW!

Book Synopsis Analysis, Synthesis and Design of Chemical Processes by : Richard Turton

Download or read book Analysis, Synthesis and Design of Chemical Processes written by Richard Turton and published by Pearson Education. This book was released on 2008-12-24 with total page 1562 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Leading Integrated Chemical Process Design Guide: Now with New Problems, New Projects, and More More than ever, effective design is the focal point of sound chemical engineering. Analysis, Synthesis, and Design of Chemical Processes, Third Edition, presents design as a creative process that integrates both the big picture and the small details–and knows which to stress when, and why. Realistic from start to finish, this book moves readers beyond classroom exercises into open-ended, real-world process problem solving. The authors introduce integrated techniques for every facet of the discipline, from finance to operations, new plant design to existing process optimization. This fully updated Third Edition presents entirely new problems at the end of every chapter. It also adds extensive coverage of batch process design, including realistic examples of equipment sizing for batch sequencing; batch scheduling for multi-product plants; improving production via intermediate storage and parallel equipment; and new optimization techniques specifically for batch processes. Coverage includes Conceptualizing and analyzing chemical processes: flow diagrams, tracing, process conditions, and more Chemical process economics: analyzing capital and manufacturing costs, and predicting or assessing profitability Synthesizing and optimizing chemical processing: experience-based principles, BFD/PFD, simulations, and more Analyzing process performance via I/O models, performance curves, and other tools Process troubleshooting and “debottlenecking” Chemical engineering design and society: ethics, professionalism, health, safety, and new “green engineering” techniques Participating successfully in chemical engineering design teams Analysis, Synthesis, and Design of Chemical Processes, Third Edition, draws on nearly 35 years of innovative chemical engineering instruction at West Virginia University. It includes suggested curricula for both single-semester and year-long design courses; case studies and design projects with practical applications; and appendixes with current equipment cost data and preliminary design information for eleven chemical processes–including seven brand new to this edition.

Cochrane Handbook for Systematic Reviews of Interventions

Author : Julian P. T. Higgins
Publisher : Wiley
ISBN 13 : 9780470699515
Total Pages : 672 pages
Book Rating : 4.6/5 (995 download)

DOWNLOAD NOW!

Book Synopsis Cochrane Handbook for Systematic Reviews of Interventions by : Julian P. T. Higgins

Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Designing Organic Syntheses

Author : Stuart Warren
Publisher : John Wiley & Sons
ISBN 13 : 9780471996125
Total Pages : 298 pages
Book Rating : 4.9/5 (961 download)

DOWNLOAD NOW!

Book Synopsis Designing Organic Syntheses by : Stuart Warren

Download or read book Designing Organic Syntheses written by Stuart Warren and published by John Wiley & Sons. This book was released on 1991-01-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teaches students to use the language of sythesis directly (utilizing the grammar of synthon and disconnection) rather than translating it into that of organic chemistry.

Evaluation Methodology Basics

Author : E. Jane Davidson
Publisher : SAGE
ISBN 13 : 9780761929307
Total Pages : 284 pages
Book Rating : 4.9/5 (293 download)

DOWNLOAD NOW!

Book Synopsis Evaluation Methodology Basics by : E. Jane Davidson

Download or read book Evaluation Methodology Basics written by E. Jane Davidson and published by SAGE. This book was released on 2005 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evaluation Methodology Basics introduces evaluation by focusing on the main kinds of 'big picture' questions that evaluations usually need to answer, and how the nature of such questions are linked to evaluation methodology choices. The author: shows how to identify the right criteria for your evaluation; discusses how to objectively figure out which criteria are more important than the others; and, delves into how to combine a mix of qualitative and quantitative data with 'relevant values' (such as needs) to draw explicitly evaluative conclusions.

Notes on the Synthesis of Form

Author : Christopher Alexander
Publisher : Harvard University Press
ISBN 13 : 9780674627512
Total Pages : 228 pages
Book Rating : 4.6/5 (275 download)

DOWNLOAD NOW!

Book Synopsis Notes on the Synthesis of Form by : Christopher Alexander

Download or read book Notes on the Synthesis of Form written by Christopher Alexander and published by Harvard University Press. This book was released on 1964 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: "These notes are about the process of design: the process of inventing things which display new physical order, organization, form, in response to function." This book, opening with these words, presents an entirely new theory of the process of design. In the first part of the book, Christopher Alexander discusses the process by which a form is adapted to the context of human needs and demands that has called it into being. He shows that such an adaptive process will be successful only if it proceeds piecemeal instead of all at once. It is for this reason that forms from traditional un-self-conscious cultures, molded not by designers but by the slow pattern of changes within tradition, are so beautifully organized and adapted. When the designer, in our own self-conscious culture, is called on to create a form that is adapted to its context he is unsuccessful, because the preconceived categories out of which he builds his picture of the problem do not correspond to the inherent components of the problem, and therefore lead only to the arbitrariness, willfulness, and lack of understanding which plague the design of modern buildings and modern cities. In the second part, Mr. Alexander presents a method by which the designer may bring his full creative imagination into play, and yet avoid the traps of irrelevant preconception. He shows that, whenever a problem is stated, it is possible to ignore existing concepts and to create new concepts, out of the structure of the problem itself, which do correspond correctly to what he calls the subsystems of the adaptive process. By treating each of these subsystems as a separate subproblem, the designer can translate the new concepts into form. The form, because of the process, will be well-adapted to its context, non-arbitrary, and correct. The mathematics underlying this method, based mainly on set theory, is fully developed in a long appendix. Another appendix demonstrates the application of the method to the design of an Indian village.

Side Reactions in Organic Synthesis

Author : Florencio Zaragoza Dörwald
Publisher : John Wiley & Sons
ISBN 13 : 3527604987
Total Pages : 389 pages
Book Rating : 4.5/5 (276 download)

DOWNLOAD NOW!

Book Synopsis Side Reactions in Organic Synthesis by : Florencio Zaragoza Dörwald

Download or read book Side Reactions in Organic Synthesis written by Florencio Zaragoza Dörwald and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates

Finding Strategiess in Organic Synthesis Planning with Case-based Reasoning

Author : A. Napoli
Publisher :
ISBN 13 :
Total Pages : 6 pages
Book Rating : 4.:/5 (897 download)

DOWNLOAD NOW!

Book Synopsis Finding Strategiess in Organic Synthesis Planning with Case-based Reasoning by : A. Napoli

Download or read book Finding Strategiess in Organic Synthesis Planning with Case-based Reasoning written by A. Napoli and published by . This book was released on 1993 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Synthesis and Meta-Analysis

Author : Harris Cooper
Publisher : SAGE Publications
ISBN 13 : 1483347044
Total Pages : 189 pages
Book Rating : 4.4/5 (833 download)

DOWNLOAD NOW!

Book Synopsis Research Synthesis and Meta-Analysis by : Harris Cooper

Download or read book Research Synthesis and Meta-Analysis written by Harris Cooper and published by SAGE Publications. This book was released on 2015-12-24 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fifth Edition of Harris Cooper′s bestselling text offers practical advice on how to conduct a synthesis of research in the social, behavioral, and health sciences. The book is written in plain language with four running examples drawn from psychology, education, and health science. With ample coverage of literature searching and the technical aspects of meta-analysis, this one-of-a-kind book applies the basic principles of sound data gathering to the task of producing a comprehensive assessment of existing research.

Understanding Experimental Planning For Advanced Level Chemistry: The Learner's Approach

Author : Kim Seng Chan
Publisher : World Scientific Publishing Company
ISBN 13 : 9814667927
Total Pages : 306 pages
Book Rating : 4.8/5 (146 download)

DOWNLOAD NOW!

Book Synopsis Understanding Experimental Planning For Advanced Level Chemistry: The Learner's Approach by : Kim Seng Chan

Download or read book Understanding Experimental Planning For Advanced Level Chemistry: The Learner's Approach written by Kim Seng Chan and published by World Scientific Publishing Company. This book was released on 2015-05-22 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a continuation of authors' previous six books — Understanding Advanced Physical Inorganic Chemistry, Understanding Advanced Organic and Analytical Chemistry, Understanding Advanced Chemistry Through Problem Solving Vol. I & II, Understanding Basic Chemistry and Understanding Basic Chemistry Through Problem Solving, retaining the main refutational characteristics of the previous books with the strategic inclusion of think-aloud questions to promote conceptual understanding during an experimental planning. These essential questions would make learners aware of the rationale behind each procedural step, the amount of chemical used and types of apparatus that are appropriate for the experiment.The book provides a fundamental important scaffolding to aid students to create their own understanding of how to plan an experiment based on the given reagent and apparatus. It guides the students in integrating the various concepts that they have learnt into a coherent and meaningful conceptual network during experimental planning.Existing A-level or IB guidebooks generally introduce concepts in a matter-of-fact manner. This book adds a unique pedagogical edge which few can rival. This book is essential and useful in order for students to be adequately prepared for their high stake examinations.