Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Eicosanoids And Radiation
Download Eicosanoids And Radiation full books in PDF, epub, and Kindle. Read online Eicosanoids And Radiation ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Eicosanoids and Radiation by : Peter Polgar
Download or read book Eicosanoids and Radiation written by Peter Polgar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostaglandins, Leukotrienes, and Cancer is a multi-volume series that will focus on an emerging area of cancer research. In 1968, R.H. Williams first reported that elevated prostaglandin levels are present in human medullary car cinoma. Since that time, the concept that arachidonic acid metabolites may be in volved in cancer has expanded to include every aspect of the disease from cell transformation through metastasis. Prostaglandins and leukotrienes are generic terms used to describe a family of bioactive lipids produced from unsaturated fatty acids (principally from arachidonic acid) via the cyclooxygenase and lipoxygenase pathways, respec tively. Cyclooxygenase products consist of diverse products such as prosta glandin Ez (PGEz), prostacyclin (PGIz) and thromboxane Az (TXAz), whereas lipoxygenase products consist of hydroperoxy fatty acids and mono-, di- and tri-hydroxy acids including leukotrienes. The precursor fatty acids for the cyclooxygenase and lipoxygenase pathways are present in cellular phospholipids. This finding established an important control point in their biosynthesis-the release of substrate. This occurs in response to numerous stimuli that act at the cell surface. Dr. Bengt Samuelsson's extensive study of the metabolism of pros taglandins indicated that they are rapidly inactivated on a single pass through pulmonary circulation. Thus, they cannot act as circulating hormones and appear to be made on demand in or in the vicinity of target tissues leading to the concept that prostaglandins are local hormones or autocoids.
Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4 by : Kenneth V. Honn
Download or read book Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4 written by Kenneth V. Honn and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains conference presentations regarding the regulation of eicosanoid enzymes and, in particular, cyclooxygenases, lipoxygenases, and phospholipases. The new field of isoprostanes is also represented.
Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury by : Santosh Nigam
Download or read book Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury written by Santosh Nigam and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent decades eicosanoids have been attracting an increasing amount of attention as a result of their important physiological roles in many areas of biology and medicine. The eicosanoids comprise the prostaglandins, thromboxanes and leukotrienes and are products of arachidonic acid, an essential polyunsaturated fatty acid stored in tissue phospholipids. Disturbances of eicosanoids and their metabolic products play a regulatory role in many types of cell injuries and diseases. One of the most exciting areas of eicosanoid research pinpoints their participation in the control of cell proliferation and differentiation. Eicosanoids form a link between different fields of research into such areas as cancer, inflammation and radiation-induced injury. This link provided the impetus for the development of the conference series of which the present volume represents the proceedings of the Second International Conference, held in Berlin in October 1991.
Book Synopsis Eicosanoids and other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3 by : Kenneth V. Honn
Download or read book Eicosanoids and other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3 written by Kenneth V. Honn and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Fourth International Conference held in Hong Kong, October 4-7, 1995
Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury by : Kenneth V. Honn
Download or read book Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury written by Kenneth V. Honn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the First International Conference on Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury held in Detroit, Michigan on October 11-14, 1989. The program consisted of 83 oral and 29 poster presentations, 74 of which are included in these proceedings. The major sponsors of the conference were the Armed Forces Radiobiology Research Institute, located in Bethesda, Maryland, the Radiation Oncology Research and Development Center of the Gershenson Radiation Oncology Center, Harper Hospital in Detroit, Michigan, and Schering AG of West Germany. Eighteen other organizations provided additional support. The conference was unique in its attempt to link the eicosanoid and lipid researchers in the radiobiology and cancer disciplines. The diverse roles that eicosanoids and other bioactive lipids play in these biological phenomena including the participation of lipid oxidation in conversion of procarcinogens, positive and negative modulation of tumor growth, immunomodulation, tissue injury, and yet protection and enhancement of cancer therapy, necessitated scientific interaction to sort out and understand these complex and sometimes contradictory observations. The success of this effort is reflected not only through these proceedings, but also through the decision to continue the conference series with a second meeting to be held in Berlin between September 17-21, 1991.
Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5 by : Kenneth V. Honn
Download or read book Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5 written by Kenneth V. Honn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents a collection of contributions from the 6th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases held in Boston from September 12-15, 1999. The mission of this meeting was to bring together senior and junior investigators to both announce and examine their recent advancements in cutting-edge research on the roles and actions of lipid mediators and their impact in human physiology and disease pathogenesis. The meeting focused on new concepts in these areas of interest to both clinicians and researchers. The program included several outstanding plenary lectures and presentations by leading experts in the fields of cancer and inflammation. In addition, the Boston meeting presented three Young Investigator awards, one in each of the major focus areas. The meeting was exciting and proved to be very memorable. The program was developed with an emphasis on recent advances in molecular and of lipid mediators relevant in cellular mechanisims involved in the formation and actions inflammation and cancer. Plenary lectures were presented by Prof. Bengt Sammuelsson (Karolinska Institute, Stockholm; 1982 Nobel Laureate in Physiology or Medicine) and Prof. E. 1. Corey (Harvard University; 1990 Nobel Laureate in Chemistry). Both of these plenary lectures were held on Day 1, which set an exciting tone for this meeting. Immediately following these plenary lectures, three simultaneous breakout sessions were held, one of inflammation, a second on cancer and synthesis of novel inhibitors, and a third on enzymes-lipoxygenases/cyclooxygenases and inhibitors.
Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 by : Kenneth V. Honn
Download or read book Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 written by Kenneth V. Honn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.
Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 by : Kenneth V. Honn
Download or read book Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 written by Kenneth V. Honn and published by Springer. This book was released on 1998-02-28 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.
Book Synopsis Eicosanoids and other bioactive lipids in cancer, inflammation and radiation injury by :
Download or read book Eicosanoids and other bioactive lipids in cancer, inflammation and radiation injury written by and published by . This book was released on 1991 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury by : Santosh K. Nigam
Download or read book Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury written by Santosh K. Nigam and published by . This book was released on 1991 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Thomas L., Jr. Walden Publisher :Springer Science & Business Media ISBN 13 :1468454579 Total Pages :405 pages Book Rating :4.4/5 (684 download)
Book Synopsis Prostaglandin and Lipid Metabolism in Radiation Injury by : Thomas L., Jr. Walden
Download or read book Prostaglandin and Lipid Metabolism in Radiation Injury written by Thomas L., Jr. Walden and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the International Conference on Prostaglandins and Lipid Metabolism in Radiation Injury held in Rockville, Maryland, on October 2-3, 1986. Over 200 persons from eight countries attended the program, which consisted of 24 oral presentations and 38 poster presentations. Forty-two of those presentations have been included in this volume. The conference was sponsored by the Armed Forces Radiobiology Research Institute, located in Bethesda, Maryland. The effects of radiation on lipid synthesis and membrane damage are aptly summarized in the first five chapters. These chapters describe the effects of radiation on lipid peroxidation of model membranes, and the role of lipid composition in mammalian cell death and in bacterial radio- and thermosensitivity. In bacteria, lipid peroxidation is not essential for radiation-induced cell death. One of the key points of the conference was the paradoxical nature of the radiobiology of eicosanoids. On the one hand, eicosanoids are mediators of damage; on the other, they are radioprotective agents. It is clear from the literature and from the data presented at the conference that both of these properties may also be observed as a consequence of radiotherapy. Some studies indicate that nonsteroidal anti-inflammatory drugs may minimize or prevent certain radiation induced damage, but other studies show no positive effect.
Book Synopsis Eicosanoids and Bioactive Lipids in Cancer & Radiation Injury by :
Download or read book Eicosanoids and Bioactive Lipids in Cancer & Radiation Injury written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury, 2nd International Conference, Berlin, September 17-21, 1991 by : Karsten Schrör
Download or read book Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury, 2nd International Conference, Berlin, September 17-21, 1991 written by Karsten Schrör and published by . This book was released on 1991 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Paradoxical Role for Eicosanoids: Radioprotectants and Radiosensitizers by :
Download or read book A Paradoxical Role for Eicosanoids: Radioprotectants and Radiosensitizers written by and published by . This book was released on 1987 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the radiobiology of eicosanoids is complicated by their ability to act as mediators of damage and recovery and as radioprotective agents. Changes in the tissue concentrations of eicosanoids following irradiation are dependent on several factors, including the type of eicosanoid, time postirradiation, radiation dose, and other contributing mediators and enzyme changes in the surrounding microenvironment. Many of these same prostaglandins and the leukotrienes have been shown to be radioprotective when given before irradiation.
Book Synopsis Eicosanoids and other bioactive lipids in cancer, inflammation and radiation injury by :
Download or read book Eicosanoids and other bioactive lipids in cancer, inflammation and radiation injury written by and published by . This book was released on 1991 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Eicosanoids and other bioactive lipids in cancer, inflammation and radiation injury by :
Download or read book Eicosanoids and other bioactive lipids in cancer, inflammation and radiation injury written by and published by . This book was released on 1991 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Radioprotectors written by Edward A. Bump and published by CRC Press. This book was released on 1997-12-29 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is essential to minimize damage to normal tissues during radiation therapy and many strategies have been employed in finding the best methods for radioprotection. This book integrates chemical, biological, and clinical perspectives on these strategies and developments, providing a comprehensive treatise. It emphasizes new concepts in radioprotection, aiming to inspire further basic science and clinical progress in radioprotector research. Radioprotectors: Chemical, Biological, and Clinical Perspectives includes the following topics: Early research on radioprotectors WR-2721, an aminothiol prodrug, as a radioprotector New results with naturally occurring thiols Nitroxides as effective radioprotectors in vitro and in vivo Radioprotection observed with radical scavengers or antioxidants Bone marrow radioprotection with cytokines and biological modifiers Multiple mechanisms of altering radiation response by eicosanoids Vascular response to radiation and the importance of vascular damage to normal tissue Modifiers of radiation-induced apoptosis Survey of clinical trials with radioprotectors Radiation biologists and oncologists, cancer researchers, and toxicologists will benefit from the findings discussed and strategies for future research.
