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Efficient Computation Of Adjusted P Values For Resampling Based Stepdown Multiple Testing
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Book Synopsis Efficient Computation of Adjusted P-Values for Resampling-Based Stepdown Multiple Testing by : Joseph P. Romano
Download or read book Efficient Computation of Adjusted P-Values for Resampling-Based Stepdown Multiple Testing written by Joseph P. Romano and published by . This book was released on 2016 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a recent interest in reporting p-values adjusted for resampling-based stepdown multiple testing procedures proposed in Romano and Wolf (2005a,b). The original papers only describe how to carry out multiple testing at a fixed significance level. Computing adjusted p-values instead in an efficient manner is not entirely trivial. Therefore, this paper fills an apparent gap by detailing such an algorithm.
Book Synopsis Testing Statistical Hypotheses by : E.L. Lehmann
Download or read book Testing Statistical Hypotheses written by E.L. Lehmann and published by Springer Nature. This book was released on 2022-06-22 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of Testing Statistical Hypotheses updates and expands upon the classic graduate text, emphasizing optimality theory for hypothesis testing and confidence sets. The principal additions include a rigorous treatment of large sample optimality, together with the requisite tools. In addition, an introduction to the theory of resampling methods such as the bootstrap is developed. The sections on multiple testing and goodness of fit testing are expanded. The text is suitable for Ph.D. students in statistics and includes over 300 new problems out of a total of more than 760.
Book Synopsis Functional and High-Dimensional Statistics and Related Fields by : Germán Aneiros
Download or read book Functional and High-Dimensional Statistics and Related Fields written by Germán Aneiros and published by Springer Nature. This book was released on 2020-06-19 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest research on the statistical analysis of functional, high-dimensional and other complex data, addressing methodological and computational aspects, as well as real-world applications. It covers topics like classification, confidence bands, density estimation, depth, diagnostic tests, dimension reduction, estimation on manifolds, high- and infinite-dimensional statistics, inference on functional data, networks, operatorial statistics, prediction, regression, robustness, sequential learning, small-ball probability, smoothing, spatial data, testing, and topological object data analysis, and includes applications in automobile engineering, criminology, drawing recognition, economics, environmetrics, medicine, mobile phone data, spectrometrics and urban environments. The book gathers selected, refereed contributions presented at the Fifth International Workshop on Functional and Operatorial Statistics (IWFOS) in Brno, Czech Republic. The workshop was originally to be held on June 24-26, 2020, but had to be postponed as a consequence of the COVID-19 pandemic. Initiated by the Working Group on Functional and Operatorial Statistics at the University of Toulouse in 2008, the IWFOS workshops provide a forum to discuss the latest trends and advances in functional statistics and related fields, and foster the exchange of ideas and international collaboration in the field.
Book Synopsis Bioinformatics and Human Genomics Research by : Diego A. Forero
Download or read book Bioinformatics and Human Genomics Research written by Diego A. Forero and published by CRC Press. This book was released on 2021-12-23 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.
Book Synopsis Journal of Environmental Accounting and Management by : Zhifeng Yang
Download or read book Journal of Environmental Accounting and Management written by Zhifeng Yang and published by L& H Scientific Publishing. This book was released on 2018-07-01 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: his peer-reviewed journal publishes original research results in the field of environmental and ecological science with focus on applications to the sustainable management of natural, human-dominated, and man-made ecosystems. The aim of the journal is to provide a place for a rapid exchange of new ideas and concepts for scientists and engineers in the fields of environmental accounting, human and systems ecology, and environmental management. Manuscripts on environmental accounting and managements are solicited, including: mathematical modeling; computational and management techniques in environmental, ecological, energy and information science; environmental technology and engineering; human managed ecosystems such as agricultural, urban, coastal, riparian, and wetland ecosystems. No length limitations for contributions are set, but only concisely written manuscripts are considered for publication. Brief papers can be published on the basis of Technical Notes. Discussions of previous published papers are welcome. Topics of Interest Environmental and ecological economics, environmental accounting, environmental impact assessment, ecosystem service assessment, energy and resource use, social factors and management.Modeling in environmental conservation and restoration, eco-hydrology and water resources management, ecological process and pattern, climate change effects, environmental engineering and technology.Planning and management in human dimension-institutions and patterns for socio-economic systems, industrial ecology, ecological informatics, landscape design, and urban planning.Environmental policy, legislation, and innovations with environmental and strategic impact assessment, project appraisal and auditing, and environmental protection.
Book Synopsis The Government Analytics Handbook by : Daniel Rogger
Download or read book The Government Analytics Handbook written by Daniel Rogger and published by World Bank Publications. This book was released on 2023-10-20 with total page 1197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Government Analytics Handbook presents frontier evidence and practitioner insights on how to leverage data to strengthen public administration. Covering a range of microdata sources—such as administrative data and public servant surveys—as well as tools and resources for undertaking the analytics, it transforms the ability of governments to take a data-informed approach to diagnose and improve how public organizations work. Readers can order the book as a single volume in print or digital formats, or visit worldbank.org/governmentanalytics for modular access and additional hands-on tools. The Handbook is a must-have for practitioners, policy makers, academics, and government agencies. “Governments have long been assessed using aggregate governance indicators, giving us little insight into their diversity and how they can practically be improved. This pioneering handbook shows how microdata can be used to give scholars and practitioners granular and real insights into how states work, and practical guidance on the process of state-building.†? —Francis Fukuyama, Stanford University, author of State-Building: Governance and World Order in the 21st Century “The Government Analytics Handbook is the most comprehensive work on practically building government administration I have ever seen, helping practitioners to change public administration for the better.†? —Francisco Gaetani, Special Secretary for State Transformation, Government of Brazil “The machinery of the state is central to a country’s prosperity. This handbook provides insights and methodological tools for creating a better shared understanding of the realities of a state, to support the redesign of institutions, and improve the quality of public administration.†? —James Robinson, University of Chicago, coauthor of Why Nations Fail
Book Synopsis Crime, Violence, and Justice in Latin America by : Carlos Solar
Download or read book Crime, Violence, and Justice in Latin America written by Carlos Solar and published by Taylor & Francis. This book was released on 2022-12-23 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book asks why crime and violence persist in Latin America at extreme levels and why the states have not been able to more effectively solve this problem that dominates the lives of many millions of Latin Americans. Informed by diverse disciplinary backgrounds, the book brings together a team of regional experts to discuss research-based explanations on some of Latin America’s most pressing criminal and violent issues distressing the rule of law. First, it examines old and new forms of observing crime upon perpetrators and victimized communities. Second, it explores the geographies of urban and rural violence and the entangled politics following organized criminality. Third, it questions how the transfer of policy knowledge and expertise reshapes local security governance, and, more importantly, critically examines the problems in implementing foreign models and paradigms in the Latin American context. Finally, it exposes the everchanging scenario of policy-making and prosecuting crime and homicide. Crime, Violence, and Justice in Latin America provides new themes and novel trends on what crime and violence mean in the eyes of observers, perpetrators, policymakers, governmental officials, and victims. It is an important acquisition for policy makers and academics alike.
Book Synopsis Multiple Testing Problems in Pharmaceutical Statistics by : Alex Dmitrienko
Download or read book Multiple Testing Problems in Pharmaceutical Statistics written by Alex Dmitrienko and published by CRC Press. This book was released on 2009-12-08 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple c
Book Synopsis Stepwise Multiple Testing as Formalized Data Snooping by : Michael Wolf
Download or read book Stepwise Multiple Testing as Formalized Data Snooping written by Michael Wolf and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is common in econometric applications that several hypothesis tests are carried out at the same time. The problem then becomes how to decide which hypotheses to reject, accounting for the multitude of tests. In this paper, we suggest a stepwise multiple testing procedure which asymptotically controls the familywise error rate at a desired level. Compared to related single-step methods, our procedure is more powerful in the sense that it often will reject more false hypotheses. Unlike some stepwise methods, our method implicitly captures the joint dependence structure of the test statistics, which results in increased ability to detect alternative hypotheses. We prove our method asymptotically controls the familywise error rate under minimal assumptions. Some simulation studies show the improvements of our methods over previous proposals. We also provide an application to a set of real data.
Book Synopsis Multiple Comparisons Using R by : Frank Bretz
Download or read book Multiple Comparisons Using R written by Frank Bretz and published by CRC Press. This book was released on 2016-04-19 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adopting a unifying theme based on maximum statistics, Multiple Comparisons Using R describes the common underlying theory of multiple comparison procedures through numerous examples. It also presents a detailed description of available software implementations in R. The R packages and source code for the analyses are available at http://CRAN.R-project.org After giving examples of multiplicity problems, the book covers general concepts and basic multiple comparisons procedures, including the Bonferroni method and Simes’ test. It then shows how to perform parametric multiple comparisons in standard linear models and general parametric models. It also introduces the multcomp package in R, which offers a convenient interface to perform multiple comparisons in a general context. Following this theoretical framework, the book explores applications involving the Dunnett test, Tukey’s all pairwise comparisons, and general multiple contrast tests for standard regression models, mixed-effects models, and parametric survival models. The last chapter reviews other multiple comparison procedures, such as resampling-based procedures, methods for group sequential or adaptive designs, and the combination of multiple comparison procedures with modeling techniques. Controlling multiplicity in experiments ensures better decision making and safeguards against false claims. A self-contained introduction to multiple comparison procedures, this book offers strategies for constructing the procedures and illustrates the framework for multiple hypotheses testing in general parametric models. It is suitable for readers with R experience but limited knowledge of multiple comparison procedures and vice versa. See Dr. Bretz discuss the book.
Book Synopsis Resampling-Based Multiple Testing by : Peter H. Westfall
Download or read book Resampling-Based Multiple Testing written by Peter H. Westfall and published by John Wiley & Sons. This book was released on 1993-01-12 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combines recent developments in resampling technology (including the bootstrap) with new methods for multiple testing that are easy to use, convenient to report and widely applicable. Software from SAS Institute is available to execute many of the methods and programming is straightforward for other applications. Explains how to summarize results using adjusted p-values which do not necessitate cumbersome table look-ups. Demonstrates how to incorporate logical constraints among hypotheses, further improving power.
Book Synopsis Statistical Parametric Mapping: The Analysis of Functional Brain Images by : William D. Penny
Download or read book Statistical Parametric Mapping: The Analysis of Functional Brain Images written by William D. Penny and published by Elsevier. This book was released on 2011-04-28 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration and comparison of the information collected. This book describes the ideas and procedures that underlie the analysis of signals produced by the brain. The aim is to understand how the brain works, in terms of its functional architecture and dynamics. This book provides the background and methodology for the analysis of all types of brain imaging data, from functional magnetic resonance imaging to magnetoencephalography. Critically, Statistical Parametric Mapping provides a widely accepted conceptual framework which allows treatment of all these different modalities. This rests on an understanding of the brain's functional anatomy and the way that measured signals are caused experimentally. The book takes the reader from the basic concepts underlying the analysis of neuroimaging data to cutting edge approaches that would be difficult to find in any other source. Critically, the material is presented in an incremental way so that the reader can understand the precedents for each new development. This book will be particularly useful to neuroscientists engaged in any form of brain mapping; who have to contend with the real-world problems of data analysis and understanding the techniques they are using. It is primarily a scientific treatment and a didactic introduction to the analysis of brain imaging data. It can be used as both a textbook for students and scientists starting to use the techniques, as well as a reference for practicing neuroscientists. The book also serves as a companion to the software packages that have been developed for brain imaging data analysis. An essential reference and companion for users of the SPM software Provides a complete description of the concepts and procedures entailed by the analysis of brain images Offers full didactic treatment of the basic mathematics behind the analysis of brain imaging data Stands as a compendium of all the advances in neuroimaging data analysis over the past decade Adopts an easy to understand and incremental approach that takes the reader from basic statistics to state of the art approaches such as Variational Bayes Structured treatment of data analysis issues that links different modalities and models Includes a series of appendices and tutorial-style chapters that makes even the most sophisticated approaches accessible
Book Synopsis Common Errors in Statistics (and How to Avoid Them) by : Phillip I. Good
Download or read book Common Errors in Statistics (and How to Avoid Them) written by Phillip I. Good and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the Second Edition "All statistics students and teachers will find in this book a friendly and intelligentguide to . . . applied statistics in practice." —Journal of Applied Statistics ". . . a very engaging and valuable book for all who use statistics in any setting." —CHOICE ". . . a concise guide to the basics of statistics, replete with examples . . . a valuablereference for more advanced statisticians as well." —MAA Reviews Now in its Third Edition, the highly readable Common Errors in Statistics (and How to Avoid Them) continues to serve as a thorough and straightforward discussion of basic statistical methods, presentations, approaches, and modeling techniques. Further enriched with new examples and counterexamples from the latest research as well as added coverage of relevant topics, this new edition of the benchmark book addresses popular mistakes often made in data collection and provides an indispensable guide to accurate statistical analysis and reporting. The authors' emphasis on careful practice, combined with a focus on the development of solutions, reveals the true value of statistics when applied correctly in any area of research. The Third Edition has been considerably expanded and revised to include: A new chapter on data quality assessment A new chapter on correlated data An expanded chapter on data analysis covering categorical and ordinal data, continuous measurements, and time-to-event data, including sections on factorial and crossover designs Revamped exercises with a stronger emphasis on solutions An extended chapter on report preparation New sections on factor analysis as well as Poisson and negative binomial regression Providing valuable, up-to-date information in the same user-friendly format as its predecessor, Common Errors in Statistics (and How to Avoid Them), Third Edition is an excellent book for students and professionals in industry, government, medicine, and the social sciences.
Book Synopsis Multiple Testing Procedures with Applications to Genomics by : Sandrine Dudoit
Download or read book Multiple Testing Procedures with Applications to Genomics written by Sandrine Dudoit and published by Springer Science & Business Media. This book was released on 2007-12-18 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.
Book Synopsis Analysis of Clinical Trials Using SAS by : Alex Dmitrienko
Download or read book Analysis of Clinical Trials Using SAS written by Alex Dmitrienko and published by SAS Institute. This book was released on 2017-07-17 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Clinical Trials Using SAS®: A Practical Guide, Second Edition bridges the gap between modern statistical methodology and real-world clinical trial applications. Tutorial material and step-by-step instructions illustrated with examples from actual trials serve to define relevant statistical approaches, describe their clinical trial applications, and implement the approaches rapidly and efficiently using the power of SAS. Topics reflect the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry and address important statistical problems encountered in clinical trials. Commonly used methods are covered, including dose-escalation and dose-finding methods that are applied in Phase I and Phase II clinical trials, as well as important trial designs and analysis strategies that are employed in Phase II and Phase III clinical trials, such as multiplicity adjustment, data monitoring, and methods for handling incomplete data. This book also features recommendations from clinical trial experts and a discussion of relevant regulatory guidelines. This new edition includes more examples and case studies, new approaches for addressing statistical problems, and the following new technological updates: SAS procedures used in group sequential trials (PROC SEQDESIGN and PROC SEQTEST) SAS procedures used in repeated measures analysis (PROC GLIMMIX and PROC GEE) macros for implementing a broad range of randomization-based methods in clinical trials, performing complex multiplicity adjustments, and investigating the design and analysis of early phase trials (Phase I dose-escalation trials and Phase II dose-finding trials) Clinical statisticians, research scientists, and graduate students in biostatistics will greatly benefit from the decades of clinical research experience and the ready-to-use SAS macros compiled in this book.
Book Synopsis Experimental Design and Data Analysis for Biologists by : Gerry P. Quinn
Download or read book Experimental Design and Data Analysis for Biologists written by Gerry P. Quinn and published by Cambridge University Press. This book was released on 2002-03-21 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models. Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models. Multivariate techniques, including classification and ordination, are then introduced. Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results. The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature. The book is supported by a website that provides all data sets, questions for each chapter and links to software.
Book Synopsis Modern Issues and Methods in Biostatistics by : Mark Chang
Download or read book Modern Issues and Methods in Biostatistics written by Mark Chang and published by Springer Science & Business Media. This book was released on 2011-07-15 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.
