Efferocytosis

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Lipid-Activated Nuclear Receptors

Author : Matthew C. Gage
Publisher : Humana Press
ISBN 13 : 9781493991297
Total Pages : 220 pages
Book Rating : 4.9/5 (912 download)

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Book Synopsis Lipid-Activated Nuclear Receptors by : Matthew C. Gage

Download or read book Lipid-Activated Nuclear Receptors written by Matthew C. Gage and published by Humana Press. This book was released on 2019-04-01 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide range of state-of-the-art methodologies and detailed protocols currently used to study the actions that lipid-activated nuclear receptors and their co-regulators have in tissues and immune cell types considered classic metabolic “powerhouses”. This includes the liver, adipose tissue, and monocytes/macrophages present in these and other metabolic tissues. While the main focus is on the oxysterol receptor or Liver X Receptor (LXR), the majority of the methods described can be easily applied to multiple nuclear receptors, as well as to other tissues or cell types. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Lipid-Activated Nuclear Receptors: Methods and Protocols serves as an ideal guide for researchers pursuing the vital study of nuclear receptor biology and beyond.

Phagocytosis: Molecular Mechanisms and Physiological Implications

Author : Esther M. Lafuente
Publisher : Frontiers Media SA
ISBN 13 : 2889661474
Total Pages : 251 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Phagocytosis: Molecular Mechanisms and Physiological Implications by : Esther M. Lafuente

Download or read book Phagocytosis: Molecular Mechanisms and Physiological Implications written by Esther M. Lafuente and published by Frontiers Media SA. This book was released on 2020-12-03 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Efferocytosis

Author : Namasivayam Nalini
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Efferocytosis by : Namasivayam Nalini

Download or read book Efferocytosis written by Namasivayam Nalini and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several cell death modes, each with a unique feature and mode of inducing cell death have been established. Cell death occurring under physiological conditions is primarily caused by apoptosis, which is a non-inflammatory or silent process, whereas necroptosis or pyroptosis is triggered by pathogen invasion, which stimulates the immune system and induces inflammation. In physiology, clearing dead cells and associated cellular debris is necessary since billions of cells die during mammalian embryogenesis and every day in adult organisms. For degradation, dead cells produced by apoptosis are quickly engulfed by macrophages. This chapter will present a description of the phagocytosis of dead and dying cells, by a process known as efferocytosis. Macrophages and, to a lesser degree, other ,Äòprofessional,Äô phagocytes (such as monocytes and dendritic cells) and ,Äònon-professional,Äô phagocytes, such as epithelial cells, conduct efferocytosis. Recent discoveries have shed light on this mechanism and how it works to preserve homeostasis of tissue, repair of tissue and health of the organism. Caspases are a large family of proteases of cysteine acting in cascades. A cascade leading to activation of caspase 3 mediates apoptosis and is responsible for killing cells, hiring macrophages, and presenting a ,Äúeat me,Äù signal(s). If macrophages do not effectively engulf apoptotic cells, they undergo secondary necrosis and release intracellular materials that reflect a molecular pattern associated with injury, which can lead to autoimmune diseases. Here, the processes of efferocytosis are illustrated and the pathophysiological effects that which occur when this phase is abrogated are highlighted.

Apoptotic and Non-apoptotic Cell Death

Author : Shigekazu Nagata
Publisher : Springer
ISBN 13 : 3319239139
Total Pages : 186 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Apoptotic and Non-apoptotic Cell Death by : Shigekazu Nagata

Download or read book Apoptotic and Non-apoptotic Cell Death written by Shigekazu Nagata and published by Springer. This book was released on 2017-04-07 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on apoptotic and non-apoptotic programmed cell death, including necroptosis, pyroptosis, and ferroptosis, and presents recent findings in the field. It discusses the crucial role that apoptotic and non-apoptotic cell death play in various pathological conditions, such as skin diseases, inflammatory bowel diseases, and virus infections. Further, it highlights the mechanisms underlying the recognition and clearance of dead cells, and the subsequent biological responses triggered by phagocytosed macrophages and factors released from dying cells. Offering insights into cell death, it is a valuable resource for researchers and clinicians developing novel strategies to treat various diseases that are closely associated with cell death.

Apoptotic Cell Clearance in Health and Disease

Author : Estee Kurant
Publisher : Frontiers Media SA
ISBN 13 : 2889456889
Total Pages : 294 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Apoptotic Cell Clearance in Health and Disease by : Estee Kurant

Download or read book Apoptotic Cell Clearance in Health and Disease written by Estee Kurant and published by Frontiers Media SA. This book was released on 2018-12-27 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearance of apoptotic cells is essential for proper development, homeostasis and termination of immune responses in multicellular organisms. Thus, cellular and molecular players taking part in the sequential events of this process are of great interest. Research in the last 20 years has indicated that specific ligands and receptors take part in the attraction of immune cells toward apoptotic targets and in the interactions between apoptotic cells and professional as well as non-professional phagocytes that engulf them. Moreover, phagocytosis of apoptotic cells (efferocytosis) leads to significant phenotypic changes in the engulfing cells suggesting that it is a major fate-determining event for phagocytes. Particularly, efferocytosis has an important impact on the inflammation-resolution axis as well as embryonic development and tissue morphogenesis. Deficiencies in these processes can result in health threats, such as autoimmunity, atherosclerosis, bone loss, obesity, infertility, neurodegeneration, fibrosis and cancer. This eBook brings together 24 original research and review manuscripts that cover various aspects of apoptotic cell removal during normal development and homeostasis as well as in tumorigenesis and regenerative processes following injury.

Macrophages in inflammation and its resolution

Author : Heiko Mühl
Publisher : Frontiers E-books
ISBN 13 : 2889190730
Total Pages : 139 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Macrophages in inflammation and its resolution by : Heiko Mühl

Download or read book Macrophages in inflammation and its resolution written by Heiko Mühl and published by Frontiers E-books. This book was released on with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macrophages were initially identified as a key element in the innate host response to infection and injury due to their phagocytic clearance and elimination of pathogenic and non-pathogenic entities. However, as macrophage research advanced it became clear that not only are these cells amenable to the acquisition of multiple plastic phenotypes during inflammatory responses to different pathogens, they also play a paramount role in the termination of inflammation and acquired immune responses. In addition, macrophages profoundly affect host physiology when they migrate to distant sites and differentiate to specialized cells, like foam cells, osteoclasts, adipose tissue- and tumor -associated macrophages and other macrophage-derived cell types. These processes are affected by the inflammation-resolution axis and can result in health threats, such as atherosclerosis, bone loss, obesity, fibrosis and cancer. This Research Topic issue will cover a wide range of topics in macrophage biology: 1. Macrophages in immune responses to pathogens 2. Macrophages in the termination of acute and acquired immunity. 3. The role of macrophages and their descendents in inflammation-associated pathologies. 4. Macrophage polarization and differentiation. Particular focus will be given to the modulation of macrophage phenotype and function following their encounter with apoptotic cells and the signaling cascades that govern these changes.

Tumor Microenvironment

Author : Alexander Birbrair
Publisher : Springer Nature
ISBN 13 : 3030731197
Total Pages : 548 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Tumor Microenvironment by : Alexander Birbrair

Download or read book Tumor Microenvironment written by Alexander Birbrair and published by Springer Nature. This book was released on 2021-10-18 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses novel concepts in cancer biology, focusing on different factors that affect the tumor microenvironment. Topics covered include sex-based differences in the tumor microenironment, dormancy in the tumor microenvironment, the influence of obesity on the tumor microenvironment, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Novel Concepts covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.

Protecting the Acutely Injured Lung: Physiologic, Mechanical, Inflammatory, and Translational Perspectives

Author : Gary Frank Nieman
Publisher : Frontiers Media SA
ISBN 13 : 2832502644
Total Pages : 241 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Protecting the Acutely Injured Lung: Physiologic, Mechanical, Inflammatory, and Translational Perspectives by : Gary Frank Nieman

Download or read book Protecting the Acutely Injured Lung: Physiologic, Mechanical, Inflammatory, and Translational Perspectives written by Gary Frank Nieman and published by Frontiers Media SA. This book was released on 2022-10-17 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Phagocytosis

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1837687390
Total Pages : 232 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Phagocytosis by :

Download or read book Phagocytosis written by and published by BoD – Books on Demand. This book was released on 2023-08-02 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phagocytosis, as an innate immune defense mechanism, is the first process to respond to pathogens. It is also one of the initiating branches of an adaptive immune response. This book provides a comprehensive overview of phagocytosis and related cells in the immune response. It presents the basics of phagocytosis as well as discusses management and therapeutic strategies for infections.

Phagocytosis and Phagosomes

Author : Roberto Botelho
Publisher : Humana
ISBN 13 : 9781493965793
Total Pages : 0 pages
Book Rating : 4.9/5 (657 download)

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Book Synopsis Phagocytosis and Phagosomes by : Roberto Botelho

Download or read book Phagocytosis and Phagosomes written by Roberto Botelho and published by Humana. This book was released on 2016-11-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details experimental approaches used to investigate phagocytosis and phagosome maturation. Chapters present methods and protocols on quantifying uptake and phagosome maturation using biophysical and biochemical approaches, proteomics, microscopy, and flow cytometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Phagocytosis and Phagosomes: Methods and Protocols aims to be an important resource for both experts in the field and for those investigators delving into phagocytosis and phagosome maturation for the first time.

Interplay Between Immunity and Fibrosis

Author : Anna-Maria Hoffmann-Vold
Publisher : Frontiers Media SA
ISBN 13 : 2889718336
Total Pages : 201 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Interplay Between Immunity and Fibrosis by : Anna-Maria Hoffmann-Vold

Download or read book Interplay Between Immunity and Fibrosis written by Anna-Maria Hoffmann-Vold and published by Frontiers Media SA. This book was released on 2021-12-20 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor Prof. Oliver Distler received financial support from Actelion, Bayer, Boehringer Ingelheim, Mitsubishi Tanabe Pharma companies. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Transport of Nutrients, Metabolites and Ions Linked to Bioenergetics: Relevance to Human Pathology

Author : Cesare Indiveri
Publisher : Frontiers Media SA
ISBN 13 : 2889716325
Total Pages : 237 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Transport of Nutrients, Metabolites and Ions Linked to Bioenergetics: Relevance to Human Pathology by : Cesare Indiveri

Download or read book Transport of Nutrients, Metabolites and Ions Linked to Bioenergetics: Relevance to Human Pathology written by Cesare Indiveri and published by Frontiers Media SA. This book was released on 2021-11-12 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multi-Omics Approaches for Decoding Heterogeneity in Cancer Immunotherapy

Author : Lin Qi
Publisher : Frontiers Media SA
ISBN 13 : 2832539653
Total Pages : 267 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Multi-Omics Approaches for Decoding Heterogeneity in Cancer Immunotherapy by : Lin Qi

Download or read book Multi-Omics Approaches for Decoding Heterogeneity in Cancer Immunotherapy written by Lin Qi and published by Frontiers Media SA. This book was released on 2023-11-22 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Cell Biology

Author :
Publisher : Academic Press
ISBN 13 : 0123947960
Total Pages : 2972 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Encyclopedia of Cell Biology by :

Download or read book Encyclopedia of Cell Biology written by and published by Academic Press. This book was released on 2015-08-07 with total page 2972 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences

Efferocytosis

Author : Aimee Michon De Cathelineau
Publisher :
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.:/5 (547 download)

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Book Synopsis Efferocytosis by : Aimee Michon De Cathelineau

Download or read book Efferocytosis written by Aimee Michon De Cathelineau and published by . This book was released on 2003 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Intestinal Stem Cell Niche

Author :
Publisher : Academic Press
ISBN 13 : 9780128134818
Total Pages : 150 pages
Book Rating : 4.1/5 (348 download)

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Book Synopsis Intestinal Stem Cell Niche by :

Download or read book Intestinal Stem Cell Niche written by and published by Academic Press. This book was released on 2018-04-24 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications. Video content illustrates such areas as protocols, transplantation techniques, and work with mice. Explores not only reviews of research, but also shares methods, protocols, and transplantation techniques Contains video content to illustrate such areas as protocols, transplantation techniques, and work with mice Each volume concentrates on one organ, making this a unique publication

Signal Transduction in Cancer and Immunity

Author :
Publisher : Academic Press
ISBN 13 : 0128237589
Total Pages : 330 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Signal Transduction in Cancer and Immunity by :

Download or read book Signal Transduction in Cancer and Immunity written by and published by Academic Press. This book was released on 2021-05-30 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal Transduction in Cancer and Immunity, Volume 361 in the International Review of Cell and Molecular Biology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the International Review of Cell and Molecular Biology series Updated release includes the latest information on signal transduction in cancer and immunity