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Download or read book Effect of Calcium Phosphate Coating and RhBMP-2 on Bone Regeneration in Rabbit Calvaria Using Poly(propylene Fumarate) Scaffolds written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Javad Parvizi
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975135512
Total Pages : 1266 pages
Book Rating : 4.9/5 (751 download)
Download or read book Orthopaedic Knowledge Update 13: Ebook without Multimedia written by Javad Parvizi and published by Lippincott Williams & Wilkins. This book was released on 2020-01-13 with total page 1266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Orthopaedic Knowledge Update 13 brings you a comprehensive synthesis of the latest clinical thinking and best practices across all orthopaedic specialty areas. Backed by clinical research, informed by practical experience, and rigorously edited by specialty thought leaders, OKU 13 is the most up-to-date resource available anywhere for delivering high-quality orthopaedic patient care today. Keep pace with the rapidly changing body of orthopaedic knowledge and clinical practice with OKU’s objective and balanced coverage.
Download or read book Bone Regenerative Efficacy of Limited-Dose Escherichia Coli–Derived RhBMP-2 With Biphasic Calcium Phosphate Carrier in Rabbit Calvarial Defect Model written by and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sun-Sik Yang
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)
Download or read book Enhanced Bone Healing with BCP Granules Implanted with BMP-2 and MSCs in a Rabbit Calvarial Defect written by Sun-Sik Yang and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this study was to evaluate the in vivo osteogenic potential of biphasic calcium phosphate (BCP), bone morphogenetic protein 2 (BMP-2), and/or mesenchymal stem cell (MSC) composites by using a rabbit calvarial defect model. Bone formation was assessed by using three different kinds of implants in rabbit calvarial defects, BCP alone, BCP/recombinant human (rh) BMP-2, and BCP/rhBMP-2/MSCs composite. The implants were harvested after 2 or 8 weeks, and the area of new bone formation was quantified by micro-computed tomography (micro-CT) and histologic studies. The highest bone formation was achieved with the BCP/rhBMP-2/MSCs treatment, and it was significantly higher than that achieved with the empty or BCP-alone treatment. The quantity of new bone at 8 weeks was greater than at 2 weeks in each group. The relative density of osteocalcin immunoreactivity also increased during this interval. These results indicate that the combination of BCP, rhBMP-2, and MSCs synergistically enhances osteogenic potential during the early healing period and could be used as a bone graft substitute.
Download or read book Bone Regeneration of Critical-sized Calvarial Defects Using RhBMP-2 written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Changsheng Liu
Publisher : Springer
ISBN 13 : 9811059756
Total Pages : 632 pages
Book Rating : 4.8/5 (11 download)
Download or read book Developments and Applications of Calcium Phosphate Bone Cements written by Changsheng Liu and published by Springer. This book was released on 2017-10-20 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a state-of-the-art review of the latest advances in developing calcium- phosphate bone cements and their applications. It covers the synthesis methods, characterization approaches, material modification and novel binders, as well as the fabrication technologies of calcium-phosphate-based biomaterials in regenerative medicine and their clinical applications. It also highlights methodologies for fabricating scaffolds, biofunctional surfaces/interfaces and subsequently modulating the host response to implantable/injectable materials, and integrates a series of discussions and insights into calcium-phosphate cements and constructs in bone regenerative medicine. As such, the book not only covers the fundamentals but also opens new avenues for meeting future challenges in research and clinical applications.
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Author : Albert Jason Haddad
Publisher : Library and Archives Canada = Bibliothèque et Archives Canada
ISBN 13 : 9780612953154
Total Pages : 202 pages
Book Rating : 4.9/5 (531 download)
Download or read book An Evaluation of Healing in Critical Sized Rabbit Calvarial Defects Using Modified Bone Substitutes [microform] written by Albert Jason Haddad and published by Library and Archives Canada = Bibliothèque et Archives Canada. This book was released on 2004 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Limitations of autogenous bone have led to the development of bone substitutes. This study evaluated whether the use of LactosorbRTM and/or calcium phosphate cements as carriers for these osteoinductive materials would allow for bone regenerative. This investigation attempted to address the issues of providing immediate protection of the brain while at the same time allowing for progressive filling of the defect with bone using two strategies. The combination of Lactosorb RTM and DBM putty demonstrated defect closure identical to the autogenous bone control group. These results suggest that these novel combinations of bone regenerative substitutes have the ability to replace our dependence on autogenous bone grafting. Thirty rabbits were divided into 3 groups. Group 1 had autogenous bone placed in one defect while the other defect remained unfilled. Group 2 had one defect filled with DBM putty and the other remained empty while a Lactosorb RTM covered both defects. Group 3 had MimixRTM, a calcium phosphate cement, placed in one defect while the other was filled with CPC/BMP.
Author : Aleksandr Ovsianikov
Publisher : Springer
ISBN 13 : 9783319454436
Total Pages : 0 pages
Book Rating : 4.4/5 (544 download)
Download or read book 3D Printing and Biofabrication written by Aleksandr Ovsianikov and published by Springer. This book was released on 2018-06-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth introduction to 3D printing and biofabrication and covers the recent advances in additive manufacturing for tissue engineering. The book is divided into two parts, the first part on 3D printing discusses conventional approaches in additive manufacturing aimed at fabrication of structures, which are seeded with cells in a subsequent step. The second part on biofabrication presents processes which integrate living cells into the fabrication process.
Author : Lisa C. du Toit
Publisher : Elsevier
ISBN 13 : 0128184728
Total Pages : 318 pages
Book Rating : 4.1/5 (281 download)
Download or read book Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering written by Lisa C. du Toit and published by Elsevier. This book was released on 2020-03-08 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient Explores the current generation of nanostructured 3D printed medical devices Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals
Author : Heung Jae Chun
Publisher : Springer
ISBN 13 : 9811309507
Total Pages : 493 pages
Book Rating : 4.8/5 (113 download)
Download or read book Cutting-Edge Enabling Technologies for Regenerative Medicine written by Heung Jae Chun and published by Springer. This book was released on 2018-10-24 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth the latest enabling technologies for regenerative medicine. The opening section examines advances in 3D bioprinting and the fabrication of electrospun and electrosprayed scaffolds. The potential applications of intelligent nanocomposites are then considered, covering, for example, graphene-based nanocomposites, intrinsically conductive polymer nanocomposites, and smart diagnostic contact lens systems. The third section is devoted to various drug delivery systems and strategies for regenerative medicine. Finally, a wide range of future enabling technologies are discussed. Examples include temperature-responsive cell culture surfaces, nanopatterned scaffolds for neural tissue engineering, and process system engineering methodologies for application in tissue development. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth novel biomaterials for regenerative medicine.
Author : Marek J. Los
Publisher : Academic Press
ISBN 13 : 0128122781
Total Pages : 249 pages
Book Rating : 4.1/5 (281 download)
Download or read book Stem Cells and Biomaterials for Regenerative Medicine written by Marek J. Los and published by Academic Press. This book was released on 2018-11-07 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells and Biomaterials for Regenerative Medicine addresses the urgent need for a compact source of information on both the cellular and biomaterial aspects of regenerative medicine. By developing a mutual understanding between three separately functioning areas of science—medicine, the latest technology, and clinical economics—the volume encourages interdisciplinary relationships that will lead to solutions for the significant challenges faced by today's regenerative medicine. Users will find sections on the homeostatic balance created by apoptosis and proliferating tissue stem cells, the naturally regenerative capacities of various tissue types, the potential regenerative benefits of iPS-generation, various differentiation protocols, and more. Written in easily accessbile language, this volume is appropriate for any professional or medical staff looking to expand their knowledge with regard to stem cells and regenerative medicine. Arms readers with key information on tissue engineering, artificial organs and biomaterials, while using broadly accessible language Provides broad introduction to, and examples of, various types of stem cells, core concepts of regenerative medicine, biomaterials, nanotechnology and nanomaterials, somatic cell transdyferentiation, and more Edited and authored by researchers with expertise in regenerative medicine, (cancer) stem cells, biomaterials, genetics and nanomaterials
Author : Anthony P. Hollander
Publisher : Springer Science & Business Media
ISBN 13 : 159259428X
Total Pages : 265 pages
Book Rating : 4.5/5 (925 download)
Download or read book Biopolymer Methods in Tissue Engineering written by Anthony P. Hollander and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an urgent need to develop new approaches to treat conditions as- ciated with the aging global population. The surgeon’s approach to many of these problems could be described as having evolved through three stages: Removal: Traditionally, diseased or badly damaged tissues and structures might simply be removed. This was appropriate for limbs and non-essential organs, but could not be applied to structures that were critical to sustain life. An additional problem was the creation of disability or physical deformity that in turn could lead to further complications. Replacement: In an effort to treat wider clinical problems, or to overcome the limitations of amputation, surgeons turned to the use of implanted materials and medical devices that could replace the functions of biological structures. This field developed rapidly in the 1960s and 1970s, with heart valve and total joint replacement becoming common. The term “biomaterial” was used increasingly to describe the materials used in these operations, and the study of biomaterials became one of the first truly interdisciplinary research fields. Today, biomaterials are employed in many millions of clinical procedures each year and they have become the mainstay of a very successful industry.
Author : Ulrich Meyer
Publisher : Springer Science & Business Media
ISBN 13 : 3540777555
Total Pages : 1049 pages
Book Rating : 4.5/5 (47 download)
Download or read book Fundamentals of Tissue Engineering and Regenerative Medicine written by Ulrich Meyer and published by Springer Science & Business Media. This book was released on 2009-02-11 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.
Author : Kaan Orhan
Publisher : Springer
ISBN 13 : 3030166414
Total Pages : 312 pages
Book Rating : 4.0/5 (31 download)
Download or read book Micro-computed Tomography (micro-CT) in Medicine and Engineering written by Kaan Orhan and published by Springer. This book was released on 2019-07-25 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on applications of micro CT, CBCT and CT in medicine and engineering, comprehensively explaining the basic principles of these techniques in detail, and describing their increasing use in the imaging field. It particularly highlights the scanning procedure, which represents the most crucial step in micro CT, and discusses in detail the reconstruction process and the artifacts related to the scanning processes, as well as the imaging software used in analysis. Written by international experts, the book illustrates the application of micro CT in different areas, such as dentistry, medicine, tissue engineering, aerospace engineering, geology, material engineering, civil engineering and additive manufacturing. Covering different areas of application, the book is of interest not only to specialists in the respective fields, but also to broader audience of professionals working in the fields of imaging and analysis, as well as to students of the different disciplines.
Author : Regis W. Haid
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805574312
Total Pages : 333 pages
Book Rating : 4.8/5 (55 download)
Download or read book Advances in Spinal Stabilization written by Regis W. Haid and published by Karger Medical and Scientific Publishers. This book was released on 2003-01-01 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keep up-to-date in this fast moving field Dramatic changes in spinal stabilization have taken place in the last years and the pace of change continues to accelerate. This volume is an excellent mirror of the evolution of spinal stabilization. It brings together the latest and most comprehensive reviews in minimally-invasive and novel surgical approaches and spinal stabilization techniques. Highlights in new biomaterials including radiolucent, bioresorbable, and standard titanium are discussed by experts. Biological advances including the use of bone morphogenetic protein in anterior lumbar interbody fusion as well as computer-assisted image-guided surgical techniques are demonstrated. The section on instrumentation and technique represents the most up-to-date advances in surgical technique and management of spinal disorders. Illustrations included in each chapter document these excellent papers. Because it is a must for all surgeons performing spinal surgery to keep up-to-date in this fast moving field this book is indispensable reading for them. Neurosurgeons and orthopedic surgeons will find a wealth of information in this volume on the developments in surgical approaches, biomaterials and implants, and biological innovations.
Author : Cato T. Laurencin
Publisher : CRC Press
ISBN 13 : 1420051830
Total Pages : 388 pages
Book Rating : 4.4/5 (2 download)
Download or read book Nanotechnology and Tissue Engineering written by Cato T. Laurencin and published by CRC Press. This book was released on 2008-06-16 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanofabrication gives us the ability to mimic biological structures with molecular level precision. Offering a natural progression of topics, Nanotechnology and Tissue Engineering: The Scaffold provides a state-of-the-art account of groundbreaking research in this rapidly emerging area of biomedical engineering. Emphasizing the importance of scaffo
Author : Sabu Thomas
Publisher : Woodhead Publishing
ISBN 13 : 0081022042
Total Pages : 500 pages
Book Rating : 4.0/5 (81 download)
Download or read book Fundamental Biomaterials: Ceramics written by Sabu Thomas and published by Woodhead Publishing. This book was released on 2018-02-16 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental Biomaterials: Ceramics provides current information on ceramics and their conversion from base materials to medical devices. Initial chapters review biomedical applications and types of ceramics, with subsequent sections focusing on the properties of ceramics, and on corrosion, degradation and wear of ceramic biomaterials. The book is ideal for researchers and professionals in the development stages of design, but is also helpful to medical researchers who need to understand and communicate the requirements of a biomaterial for a specific application. This title is the second in a three volume set, with each reviewing the most important and commonly used classes of biomaterials and providing comprehensive information on material properties, behavior, biocompatibility and applications. In addition, with the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for large number of students at undergraduate and post graduate levels Provides current information on findings and developments of ceramics and their conversion from base materials to medical devices Includes analyses of the types of ceramics and a discussion of a range of biomedical applications and essential properties, including information on corrosion, degradation and wear, and lifetime prediction of ceramic biomaterials Explores both theoretical and practical aspects of ceramics in biomaterials
