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Book Synopsis Network Meta-Analysis for Decision-Making by : Sofia Dias
Download or read book Network Meta-Analysis for Decision-Making written by Sofia Dias and published by John Wiley & Sons. This book was released on 2018-03-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question "for this pre-identified population of patients, which treatment is 'best'?" A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. Network Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.
Book Synopsis Yearbook of International Organizations by :
Download or read book Yearbook of International Organizations written by and published by . This book was released on 1967 with total page 1752 pages. Available in PDF, EPUB and Kindle. Book excerpt: A directory of associations, intergovernmental bodies, religious groups, and other international organizations.
Book Synopsis The Taxonomy of Ground Stone Woodworking Tools by : Quentin Mackie
Download or read book The Taxonomy of Ground Stone Woodworking Tools written by Quentin Mackie and published by British Archaeological Reports Oxford Limited. This book was released on 1995 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multivariate study of approximately 1,500 ground stone tools (celts) from the Coast Salishan cultural area of British Columbia, Canada, forms the basis of this book. The traditional and often unthinking quest to find types within this largely unclassified class of material formed the starting point to the author's work. When statistical methods failed to discriminate betweenn typological groups, Mackie was forced to think more creatively about the behavioural environment of their use., especially how use-life would alter shape. This book is therefore both a study of stone tools and an exploration into archaeological systematics which problematises the manic classificatory zeal which is such a peculiar feature of most archaeologists.
Book Synopsis Understanding Cybercrime by : United Nations Publications
Download or read book Understanding Cybercrime written by United Nations Publications and published by UN. This book was released on 2017-07-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyber attacks are on the rise. The media constantly report about data breaches and increasingly sophisticated cybercrime. Even governments are affected. At the same time, it is obvious that technology alone cannot solve the problem. What can countries do? Which issues can be addressed by policies and legislation? How to draft a good law? The report assists countries in understanding what cybercrime is about, what the challenges are in fighting such crime and supports them in drafting policies and laws.
Book Synopsis The Monthly Army List by : Great Britain. Army
Download or read book The Monthly Army List written by Great Britain. Army and published by . This book was released on 1917 with total page 3086 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1902 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Electrical Engin Hdbk The by : Richard C. Dorf
Download or read book Electrical Engin Hdbk The written by Richard C. Dorf and published by CRC Press. This book was released on 1993-04-03 with total page 2708 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive source of electrical engineering information, this text features a complete section devoted to key mathematical formulae, concepts, definitions and derivatives. It also provides complete descriptions of select US and international professional and academic societies.
Book Synopsis Sylloge of Coins of the British Isles: The Royal Danish Collection , Copenhagen. pt. 3. A, B and C. Cnut, by G. Galster. 3 v by : Colin Stewart Sinclair Lyon
Download or read book Sylloge of Coins of the British Isles: The Royal Danish Collection , Copenhagen. pt. 3. A, B and C. Cnut, by G. Galster. 3 v written by Colin Stewart Sinclair Lyon and published by . This book was released on 1970 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Future of Intelligence by : Mark M. Lowenthal
Download or read book The Future of Intelligence written by Mark M. Lowenthal and published by John Wiley & Sons. This book was released on 2017-08-31 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intelligence is, by definition, a shadowy business. Yet many aspects of this secret world are now more openly analyzed and discussed, a trend which has inevitably prompted lively debate about intelligence gathering and analysis: what should be allowed? What boundaries, if any, should be drawn? And what changes and challenges lie ahead for intelligence activities and agencies? In this compelling book, leading intelligence scholar Mark Lowenthal explores the future of intelligence. There are, he argues, three broad areas – information technology and intelligence collection; analysis; and governance – that indicate the potential for rather dramatic change in the world of intelligence. But whether these important vectors for change will improve how intelligence works or make it more difficult remains to be seen. The only certainty is that intelligence will remain an essential feature of statecraft in our increasingly dangerous world. Drawing on the author's forty years' experience in U.S. intelligence, The Future of Intelligence offers a broad and authoritative starting point for the ongoing debate about what intelligence could be and how it may function in the years ahead.
Book Synopsis Intelligence Collection by : Robert M. Clark
Download or read book Intelligence Collection written by Robert M. Clark and published by CQ Press. This book was released on 2013-09-13 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book by one of the foremost authorities in the field offers systematic and analytical coverage of the "how and why" of intelligence collection across its three major stages—the front end (planning), collection, and the back end (processing, exploitation, and dissemination). The book provides a fresh, logical, and easily understandable view of complex collection systems used worldwide. Its ground-breaking organizational approach facilitates understanding and cross-INT collaboration, highlighting the similarities and differences among the collection INTs. The first part of the book explains how the literal INTs—open source, human intelligence, communications intelligence, and cyber collection—work. The second part focuses on nonliteral or technical INTs including imagery, electronic intelligence, and measurements and signatures intelligence. All chapters use a common format based on systems analysis methodology, detailing function, process, and structure of the collection disciplines. The third part is a complete chapter discussing the complexities of collection management in the United States. Rich, full color illustrations accompany the text with examples throughout the book on topics as diverse as battlespace situational awareness, terrorism, weapons proliferation, criminal networks, treaty monitoring, and identity intelligence.
Book Synopsis DNA Topoisomerases in Cancer Therapy by : Toshiwo Andoh
Download or read book DNA Topoisomerases in Cancer Therapy written by Toshiwo Andoh and published by Springer Science & Business Media. This book was released on 2003-06-30 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume commemorates the 30th anniversary of the discovery in 1971 of the first DNA topoisomerases, i.e topoisomerase I in E. coli, then provisionally named `omega' protein, by the pioneering work of Jim Wang at Harvard University, who has contributed an article to this volume: `Reflections on an accidental discovery' of the enzyme. Many kinds of topoisomerase have since been found from type I through to type VI in a variety of organisms ranging from viruses to higher eukaryote mammals. The wide distribution of enzymes in various forms of life implies that the DNA topoisomerase is essential for life. In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University. Readers will find a series of chapters written by researchers actively engaged in the expanding field of topoisomerase and their inhibitors. The series of chapters cover review articles on pharmacology and the molecular mechanism of topoisomerase I- and II-targeting anticancer drugs in mammals and in the yeast Saccharomyces cerevisiae, which has proved to be a superb model organism for studies of anticancer drugs. This volume compiles up-to-date information on the topoisomerase-targeting compounds in clinical and preclinical development as a useful and important reference book for students and researchers in the field of pharmacology, toxicology, oncology and molecular biology.
Download or read book Daily Graphs written by and published by . This book was released on 1984-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Assessing the Tradecraft of Intelligence Analysis by : Gregory F. Treverton
Download or read book Assessing the Tradecraft of Intelligence Analysis written by Gregory F. Treverton and published by Rand Corporation. This book was released on 2008-02-27 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report assesses intelligence analysis across the main U.S. intelligence agencies and makes a number of recommendations, some of which parallel initiatives that have begun in the wake of the December 2004 legislation, for instance, create a Deputy Director of National Intelligence as a focal point for analysis, establish a National Intelligence University, build a Long Term Analysis Unit at the National Intelligence Council, and form an Open Source Center for making more creative use of open-source materials.
Book Synopsis Improving Intelligence Analysis by : Stephen Marrin
Download or read book Improving Intelligence Analysis written by Stephen Marrin and published by Routledge. This book was released on 2012-08-21 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on intelligence analysis written by intelligence expert Dr. Stephen Marrin argues that scholarship can play a valuable role in improving intelligence analysis. Improving intelligence analysis requires bridging the gap between scholarship and practice. Compared to the more established academic disciplines of political science and international relations, intelligence studies scholarship is generally quite relevant to practice. Yet a substantial gap exists nonetheless. Even though there are many intelligence analysts, very few of them are aware of the various writings on intelligence analysis which could help them improve their own processes and products. If the gap between scholarship and practice were to be bridged, practitioners would be able to access and exploit the literature in order to acquire new ways to think about, frame, conceptualize, and improve the analytic process and the resulting product. This volume contributes to the broader discussion regarding mechanisms and methods for improving intelligence analysis processes and products. It synthesizes these articles into a coherent whole, linking them together through common themes, and emphasizes the broader vision of intelligence analysis in the introduction and conclusion chapters. The book will be of great interest to students of intelligence studies, strategic studies, US national security, US foreign policy, security studies and political science in general,as well as professional intelligence analysts and managers.
Book Synopsis Intelligence Analysis for Tomorrow by : National Research Council
Download or read book Intelligence Analysis for Tomorrow written by National Research Council and published by National Academies Press. This book was released on 2011-04-08 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intelligence community (IC) plays an essential role in the national security of the United States. Decision makers rely on IC analyses and predictions to reduce uncertainty and to provide warnings about everything from international diplomatic relations to overseas conflicts. In today's complex and rapidly changing world, it is more important than ever that analytic products be accurate and timely. Recognizing that need, the IC has been actively seeking ways to improve its performance and expand its capabilities. In 2008, the Office of the Director of National Intelligence (ODNI) asked the National Research Council (NRC) to establish a committee to synthesize and assess evidence from the behavioral and social sciences relevant to analytic methods and their potential application for the U.S. intelligence community. In Intelligence Analysis for Tomorrow: Advances from the Behavioral and Social Sciences, the NRC offers the Director of National Intelligence (DNI) recommendations to address many of the IC's challenges. Intelligence Analysis for Tomorrow asserts that one of the most important things that the IC can learn from the behavioral and social sciences is how to characterize and evaluate its analytic assumptions, methods, technologies, and management practices. Behavioral and social scientific knowledge can help the IC to understand and improve all phases of the analytic cycle: how to recruit, select, train, and motivate analysts; how to master and deploy the most suitable analytic methods; how to organize the day-to-day work of analysts, as individuals and teams; and how to communicate with its customers. The report makes five broad recommendations which offer practical ways to apply the behavioral and social sciences, which will bring the IC substantial immediate and longer-term benefits with modest costs and minimal disruption.
Book Synopsis The Palgrave Handbook of Security, Risk and Intelligence by : Robert Dover
Download or read book The Palgrave Handbook of Security, Risk and Intelligence written by Robert Dover and published by Springer. This book was released on 2017-07-05 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides a detailed analysis of threats and risk in the international system and of how governments and their intelligence services must adapt and function in order to manage the evolving security environment. This environment, now and for the foreseeable future, is characterised by complexity. The development of disruptive digital technologies; the vulnerability of critical national infrastructure; asymmetric threats such as terrorism; the privatisation of national intelligence capabilities: all have far reaching implications for security and risk management. The leading academics and practitioners who have contributed to this handbook have all done so with the objective of cutting through the complexity, and providing insight on the most pressing security, intelligence, and risk factors today. They explore the changing nature of conflict and crises; interaction of the global with the local; the impact of technological; the proliferation of hostile ideologies and the challenge this poses to traditional models of intelligence; and the impact of all these factors on governance and ethical frameworks. The handbook is an invaluable resource for students and professionals concerned with contemporary security and how national intelligence must adapt to remain effective.
Book Synopsis Intelligence Analysis by : National Research Council
Download or read book Intelligence Analysis written by National Research Council and published by National Academies Press. This book was released on 2011-03-08 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. intelligence community (IC) is a complex human enterprise whose success depends on how well the people in it perform their work. Although often aided by sophisticated technologies, these people ultimately rely on their own intellect to identify, synthesize, and communicate the information on which the nation's security depends. The IC's success depends on having trained, motivated, and thoughtful people working within organizations able to understand, value, and coordinate their capabilities. Intelligence Analysis provides up-to-date scientific guidance for the intelligence community (IC) so that it might improve individual and group judgments, communication between analysts, and analytic processes. The papers in this volume provide the detailed evidentiary base for the National Research Council's report, Intelligence Analysis for Tomorrow: Advances from the Behavioral and Social Sciences. The opening chapter focuses on the structure, missions, operations, and characteristics of the IC while the following 12 papers provide in-depth reviews of key topics in three areas: analytic methods, analysts, and organizations. Informed by the IC's unique missions and constraints, each paper documents the latest advancements of the relevant science and is a stand-alone resource for the IC's leadership and workforce. The collection allows readers to focus on one area of interest (analytic methods, analysts, or organizations) or even one particular aspect of a category. As a collection, the volume provides a broad perspective of the issues involved in making difficult decisions, which is at the heart of intelligence analysis.
