Economic Evaluation of Cancer Drugs

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Author :
Publisher : CRC Press
ISBN 13 : 0429531842
Total Pages : 334 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Economic Evaluation of Cancer Drugs by : Iftekhar Khan

Download or read book Economic Evaluation of Cancer Drugs written by Iftekhar Khan and published by CRC Press. This book was released on 2019-06-14 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems. With advances in the diagnosis and treatment, more people are diagnosed early and receive treatments for a disease where few treatments options were previously available. As a result, the survival of patients with cancer has steadily improved and, in most cases, patients who are not cured may receive multiple lines of treatment, often with financial consequences for the patients, insurers and healthcare systems. Although many books exist that address economic evaluation, Economic Evaluation of Cancer Drugs using Clinical Trial and Real World Data is the first unified text that specifically addresses the economic evaluation of cancer drugs. The authors discuss how to perform cost-effectiveness analyses while emphasising the strategic importance of designing cost-effectiveness into cancer trials and building robust economic evaluation models that have a higher chance of reimbursement if truly cost-effective. They cover the use of real-world data using cancer registries and discuss how such data can support or complement clinical trials with limited follow up. Lessons learned from failed reimbursement attempts, factors predictive of successful reimbursement and the different payer requirements across major countries including US, Australia, Canada, UK, Germany, France and Italy are also discussed. The book includes many detailed practical examples, case studies and thought-provoking exercises for use in classroom and seminar discussions. Iftekhar Khan is a medical statistician and health economist and a lead statistician at Oxford Unviersity’s Center for Statistics in Medicine. Professor Khan is also a Senior Research Fellow in Health Economics at University of Warwick and is a Senior Statistical Assessor within the Licensing Division of the UK Medicine and Health Regulation Agency. Ralph Crott is a former professor in Pharmacoeconomics at the University of Montreal in Quebec, Canada and former head of the EORTC Health Economics Unit and former senior health economist at the Belgian HTA organization. Zahid Bashir has over twelve years experience working in the pharmaceutical industry in medical affairs and oncology drug development where he is involved in the design and execution of oncology clinical trials and development of reimbursement dossiers for HTA submission.

Economic Evaluation of Cancer Drugs

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Author :
Publisher : Chapman & Hall/CRC
ISBN 13 : 9780429546549
Total Pages : 416 pages
Book Rating : 4.5/5 (465 download)

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Book Synopsis Economic Evaluation of Cancer Drugs by : Iftekhar Khan (Statistician)

Download or read book Economic Evaluation of Cancer Drugs written by Iftekhar Khan (Statistician) and published by Chapman & Hall/CRC. This book was released on 2019-06-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems. With advances in the diagnosis and treatment, more people are diagnosed early and receive treatments for a disease where few treatments options were previously available. As a result, the survival of patients with cancer has steadily improved and, in most cases, patients who are not cured may receive multiple lines of treatment, often with financial consequences for the patients, insurers and healthcare systems. Although many books exist that address economic evaluation, Economic Evaluation of Cancer Drugs using Clinical Trial and Real World Data is the first unified text that specifically addresses the economic evaluation of cancer drugs. The authors discuss how to perform cost-effectiveness analyses while emphasising the strategic importance of designing cost-effectiveness into cancer trials and building robust economic evaluation models that have a higher chance of reimbursement if truly cost-effective. They cover the use of real-world data using cancer registries and discuss how such data can support or complement clinical trials with limited follow up. Lessons learned from failed reimbursement attempts, factors predictive of successful reimbursement and the different payer requirements across major countries including US, Australia, Canada, UK, Germany, France and Italy are also discussed. The book includes many detailed practical examples, case studies and thought-provoking exercises for use in classroom and seminar discussions. Iftekhar Khan is a medical statistician and health economist and a lead statistician at Oxford Unviersity's Center for Statistics in Medicine. Professor Khan is also a Senior Research Fellow in Health Economics at University of Warwick and is a Senior Statistical Assessor within the Licensing Division of the UK Medicine and Health Regulation Agency. Ralph Crott is a former professor in Pharmacoeconomics? at the University of Montreal in Quebec, Canada and former head of the EORTC Health Economics Unit and former senior health economist at the Belgian HTA organization. Zahid Bashir has over twelve years experience working in the pharmaceutical industry in medical affairs and oncology drug development where he is involved in the design and execution of oncology clinical trials and development of reimbursement dossiers for HTA submission.

Assessing the Economic Value of Anticancer Therapies

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642721230
Total Pages : 294 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Assessing the Economic Value of Anticancer Therapies by : Niels Neymark

Download or read book Assessing the Economic Value of Anticancer Therapies written by Niels Neymark and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: With ever increasing demands on the constrained resources available for health care services, no one involved in decision making in health care can continue to ignore the economic costs of the services provided or the relative value for money offered by the available treatments. Economic evaluation has therefore become an important and indispensable tool for medical deci sion making, alongside the well-known methods for clinical eval uation. This is also true for cancer, despite the aura of sanctity often of surrounding this dreaded disease and the apparent willingness the general population to spend large sums in this area and do "everything possible" for the patients. In recent years, articles dealing with assessing the costs and benefits of various cancer treatments have begun to appear in scientific medical and eco nomic journals. This book provides a comprehensive survey and assessment of the current state of the art of economic evaluations and cost ana lyses in cancer. It gives an introduction to the methods available for economic evaluations, before surveying and assessing the available publications. Separate chapters are devoted to the most prevalent cancers, and in each chapter the current clinical prac tice and research problems are summarized in order to provide a background for the economic analyses. At the end, a summary assessment of the literature is provided along with some sugges tions for a future research agenda.

Regulatory and Economic Aspects in Oncology

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Author :
Publisher : Springer
ISBN 13 : 3030012077
Total Pages : 205 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Regulatory and Economic Aspects in Oncology by : Evelyn Walter

Download or read book Regulatory and Economic Aspects in Oncology written by Evelyn Walter and published by Springer. This book was released on 2018-12-13 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores topics of importance to all who have an interest in economic methods for assessment of the efficacy and effectiveness of new cancer treatments and in regulatory measures relating to their marketing authorization and pricing. Targeted therapies and modern immunotherapy are placing a substantial strain on health care budgets. Regulation and economic methods to assess the parameters for establishing efficacy and effectiveness are therefore of prime importance. Payer authorities have to determine whether the use of these novel therapies yields clinical benefits that justify their increasing cost. In the simplest terms, cost-effectiveness analyses quantify the ratio between the extent to which an intervention raises healthcare costs and the extent to which it improves health outcomes. Rigorous cost-effectiveness analyses translate all health outcomes into quality-adjusted life years. On the other hand, in order to sustain innovation, price regulations must be coupled with efforts to ensure that drug companies are still able to recoup their investments in high-risk and high-costs research programs. Ultimately, decisions regarding health care expenditures are also a question of society’s willingness to pay.

Economic Evaluation of Cancer Treatments

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Publisher :
ISBN 13 : 9789090085289
Total Pages : 233 pages
Book Rating : 4.0/5 (852 download)

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Book Synopsis Economic Evaluation of Cancer Treatments by : Cornelia Aaltje Groot

Download or read book Economic Evaluation of Cancer Treatments written by Cornelia Aaltje Groot and published by . This book was released on 1995 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Integrating Economic Analysis Into Cancer Clinical Trials

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Publisher :
ISBN 13 :
Total Pages : 42 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Integrating Economic Analysis Into Cancer Clinical Trials by : Martin Brown

Download or read book Integrating Economic Analysis Into Cancer Clinical Trials written by Martin Brown and published by . This book was released on 1998 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical economics is a new and evolving discipline that addresses the economic implications of changes in medical practice. As applied to cancer care, clinical economics assesses the costs and effectiveness of new cancer interventions and can be a valuable endpoint in selected clinical trials. Through the integration of economics into clinical evaluations, information can be developed that contributes to the decisions of patients, clinicians, health care managers, and policymakers as to the most effective allocation of cancer care resources.

Equitable Access to High-Cost Pharmaceuticals

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Publisher : Academic Press
ISBN 13 : 0128119624
Total Pages : 240 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Equitable Access to High-Cost Pharmaceuticals by : Zaheer-Ud-Din Babar

Download or read book Equitable Access to High-Cost Pharmaceuticals written by Zaheer-Ud-Din Babar and published by Academic Press. This book was released on 2018-02-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Equitable Access to High-Cost Pharmaceuticals seeks to aid the development and implementation of equitable public health policies by pharmaco-economics professionals, health economists, and policymakers. With detailed country-by country analysis of policy and regulation, the Work compares and contrasts national healthcare systems to support researchers and practitioners identify optimal healthcare policy solutions. The Work incorporates chapters on global regulatory changes, health technology assessment guidelines, and competitive effectiveness research recommendations from international bodies such as the OECD or the EU. Novel policies such as horizon scanning, managed-entry agreement and post-launch monitoring are considered in detail. The Work also thoroughly reviews novel pharmaceuticals with particular research interest, including cancer drugs, orphan medicines, Hep C, and personalized medicines. Evaluates impact and efficacy of current access policies and pricing regulation of high-cost drugs Incorporates existing guidelines and recommendations by international organizations Compares and contrasts how different countries fund and police high-cost drug access Explores novel and emergent policies, including managed entry agreement, analysis of real world data and differential pricing Reviews novel pharmaceuticals of current research interest

WHO guideline on country pharmaceutical pricing policies

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Author :
Publisher : World Health Organization
ISBN 13 : 9240011870
Total Pages : 70 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO guideline on country pharmaceutical pricing policies by :

Download or read book WHO guideline on country pharmaceutical pricing policies written by and published by World Health Organization. This book was released on 2020-09-29 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, high prices of pharmaceutical products have posed challenges in high- and low-income countries alike. In many instances, high prices of pharmaceutical products have led to significant financial hardship for individuals and negatively impacted on healthcare systems' ability to provide population-wide access to essential medicines. Pharmaceutical pricing policies need to be carefully planned, carried out, and regularly checked and revised according to changing conditions. Strong, well-thought-out policies can guide well-informed and balanced decisions to achieve affordable access to essential health products. This guideline replaces the 2015 WHO guideline on country pharmaceutical pricing policies, revised to reflect the growing body of literature since the last evidence review in 2010. This update also recognizes country experiences in managing the prices of pharmaceutical products.

Exercise Oncology

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Publisher : Springer Nature
ISBN 13 : 3030420116
Total Pages : 438 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Exercise Oncology by : Kathryn H. Schmitz

Download or read book Exercise Oncology written by Kathryn H. Schmitz and published by Springer Nature. This book was released on 2020-05-04 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking book presents a unique and practical approach to the evolving field of exercise oncology - the study of physical activity in the context of cancer prevention and control. Presenting the current state of the art, the book is sensibly divided into four thematic sections. Following an opening chapter presenting an overview and timeline of exercise oncology, the chapters comprising part I discuss primary cancer prevention, physical activity and survivorship, and the mechanisms by which these operate. Diagnosis and treatment considerations are discussed in part II, including prehabilitation, exercise during surgical recovery, infusion and radiation therapies, and treatment efficacy. Post-treatment and end-of-life care are covered in part III, including cardio-oncology, energetics and palliative care. Part IV presents behavioral, logistical and policy-making considerations, highlighting a multidisciplinary approach to exercise oncology as well as practical matters such as reimbursement and economics. Written and edited by experts in the field, Exercise Oncology will be a go-to practical resource for sports medicine clinicians, family and primary care physicians, oncologists, physical therapy and rehabilitation specialists, and all medical professionals who treat cancer patients.

Employing PROs in Economic Evaluation Studies on Treatments of Cancer Patients with Prescription Medications

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (796 download)

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Book Synopsis Employing PROs in Economic Evaluation Studies on Treatments of Cancer Patients with Prescription Medications by : Jia Liu

Download or read book Employing PROs in Economic Evaluation Studies on Treatments of Cancer Patients with Prescription Medications written by Jia Liu and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Assessing and Improving Value in Cancer Care

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Publisher : National Academies Press
ISBN 13 : 0309138140
Total Pages : 164 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Assessing and Improving Value in Cancer Care by : Institute of Medicine

Download or read book Assessing and Improving Value in Cancer Care written by Institute of Medicine and published by National Academies Press. This book was released on 2009-11-30 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlike many other areas in health care, the practice of oncology presents unique challenges that make assessing and improving value especially complex. First, patients and professionals feel a well-justified sense of urgency to treat for cure, and if cure is not possible, to extend life and reduce the burden of disease. Second, treatments are often both life sparing and highly toxic. Third, distinctive payment structures for cancer medicines are intertwined with practice. Fourth, providers often face tremendous pressure to apply the newest technologies to patients who fail to respond to established treatments, even when the evidence supporting those technologies is incomplete or uncertain, and providers may be reluctant to stop toxic treatments and move to palliation, even at the end of life. Finally, the newest and most novel treatments in oncology are among the most costly in medicine. This volume summarizes the results of a workshop that addressed these issues from multiple perspectives, including those of patients and patient advocates, providers, insurers, health care researchers, federal agencies, and industry. Its broad goal was to describe value in oncology in a complete and nuanced way, to better inform decisions regarding developing, evaluating, prescribing, and paying for cancer therapeutics.

Socioeconomic Evaluation of Drug Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642613667
Total Pages : 251 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Socioeconomic Evaluation of Drug Therapy by : Wilhelm van Eimeren

Download or read book Socioeconomic Evaluation of Drug Therapy written by Wilhelm van Eimeren and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern drugs are invented according to medical needs, making use of the latest innovations in technology. They are sophisticated, efficacious, and costly, but are they effective? Are they superior to existing - and cheaper - alternatives, and is this superiority reflected in increased cost-effectiveness? Are they socially more beneficial? These questions, and those related to the intriguing search for better quality of life, are addressed in this book by experts from the fields of medicine, epidemiology, economics, sociology and the pharmaceutical industry. The book describes the environmental situation in the United States and Europe in which pharmaceutical development takes place; it also explores the grounds for agreement as well as disagreement between the social and the economic evaluations of progress. It tackles the problem of outcome measurements, patients' behavior, quality of life, and individual value judgments and describes methodological boundaries in the socioeconomic evaluation of drugs.

The Future of Health Economics

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Author :
Publisher : Taylor & Francis
ISBN 13 : 1317031121
Total Pages : 307 pages
Book Rating : 4.3/5 (17 download)

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Book Synopsis The Future of Health Economics by : Olivier Ethgen

Download or read book The Future of Health Economics written by Olivier Ethgen and published by Taylor & Francis. This book was released on 2016-10-14 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry faces a well-documented perfect storm: on the one hand, the patent cliff; the lack of new blockbusters and, on the other, economic pressure on pricing from markets with growing expectations and shrinking budgets. In the face of such pressure, traditional health economics models no longer seem appropriate and yet what do we have to replace them? The growing focus on 'value' and 'cost effectiveness' are evidence of new emerging thinking although, even here, with the shift from medicine as cure to medicine as palliative, as a treatment for chronic illness and with the growing emphasis on preventative approaches, the landscape is complex and challenging. The Future of Health Economics offers a window into some of the most influential emerging issues in pharmacoeconomics; issues such as risk-sharing and alternative pricing models or the potential impact of radical new approaches such as personalized medicine; as well as exploring the changing role of government and regulators. Ulf Staginnus and Olivier Ethgen, themselves two of the most well-regarded practitioners in this field, have brought together some leading-edge thinkers from industry and academia around the world to provide the industry, policy-makers, regulators, health practitioners and academics with the raw material for their future scenarios.

Health at a Glance 2019 OECD Indicators

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Publisher : OECD Publishing
ISBN 13 : 9264807667
Total Pages : 243 pages
Book Rating : 4.2/5 (648 download)

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Book Synopsis Health at a Glance 2019 OECD Indicators by : OECD

Download or read book Health at a Glance 2019 OECD Indicators written by OECD and published by OECD Publishing. This book was released on 2019-11-07 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health at a Glance compares key indicators for population health and health system performance across OECD members, candidate and partner countries. It highlights how countries differ in terms of the health status and health-seeking behaviour of their citizens; access to and quality of health care; and the resources available for health. Analysis is based on the latest comparable data across 80 indicators, with data coming from official national statistics, unless otherwise stated.

Principles of Pharmacoeconomics

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Publisher :
ISBN 13 :
Total Pages : 172 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Principles of Pharmacoeconomics by : William F. McGhan

Download or read book Principles of Pharmacoeconomics written by William F. McGhan and published by . This book was released on 1991 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Economic Evaluation of Cancer Drugs

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Author :
Publisher : CRC Press
ISBN 13 : 1498761313
Total Pages : 416 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Economic Evaluation of Cancer Drugs by : Iftekhar Khan

Download or read book Economic Evaluation of Cancer Drugs written by Iftekhar Khan and published by CRC Press. This book was released on 2019-06-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems. With advances in the diagnosis and treatment, more people are diagnosed early and receive treatments for a disease where few treatments options were previously available. As a result, the survival of patients with cancer has steadily improved and, in most cases, patients who are not cured may receive multiple lines of treatment, often with financial consequences for the patients, insurers and healthcare systems. Although many books exist that address economic evaluation, Economic Evaluation of Cancer Drugs using Clinical Trial and Real World Data is the first unified text that specifically addresses the economic evaluation of cancer drugs. The authors discuss how to perform cost-effectiveness analyses while emphasising the strategic importance of designing cost-effectiveness into cancer trials and building robust economic evaluation models that have a higher chance of reimbursement if truly cost-effective. They cover the use of real-world data using cancer registries and discuss how such data can support or complement clinical trials with limited follow up. Lessons learned from failed reimbursement attempts, factors predictive of successful reimbursement and the different payer requirements across major countries including US, Australia, Canada, UK, Germany, France and Italy are also discussed. The book includes many detailed practical examples, case studies and thought-provoking exercises for use in classroom and seminar discussions. Iftekhar Khan is a medical statistician and health economist and a lead statistician at Oxford Unviersity’s Center for Statistics in Medicine. Professor Khan is also a Senior Research Fellow in Health Economics at University of Warwick and is a Senior Statistical Assessor within the Licensing Division of the UK Medicine and Health Regulation Agency. Ralph Crott is a former professor in Pharmacoeconomics at the University of Montreal in Quebec, Canada and former head of the EORTC Health Economics Unit and former senior health economist at the Belgian HTA organization. Zahid Bashir has over twelve years experience working in the pharmaceutical industry in medical affairs and oncology drug development where he is involved in the design and execution of oncology clinical trials and development of reimbursement dossiers for HTA submission.

Health Economic Evaluation of Bevacizumab for Metastatic Colorectal Cancer

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Health Economic Evaluation of Bevacizumab for Metastatic Colorectal Cancer by :

Download or read book Health Economic Evaluation of Bevacizumab for Metastatic Colorectal Cancer written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: