Early Trauma As The Origin Of Chronic Inflammation

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Early Trauma as the Origin of Chronic Inflammation

Author : Rainer H. Straub
Publisher :
ISBN 13 : 9783662667521
Total Pages : 0 pages
Book Rating : 4.6/5 (675 download)

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Book Synopsis Early Trauma as the Origin of Chronic Inflammation by : Rainer H. Straub

Download or read book Early Trauma as the Origin of Chronic Inflammation written by Rainer H. Straub and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to sensitize physicians and researchers to the important long-term health effects of early, persistent, and severe trauma. The author, an internist, rheumatologist, and basic researcher in psychoneuroimmunology, shows connections between adverse childhood experiences and typical adult sequelae. After early traumatic experiences and childhood stress, there is a higher incidence of mental illness, chronic pain, sleep disorders, dental problems, obesity, cardiovascular disease, asthma, diabetes mellitus and chronic inflammation. A selection of diseases unmistakably demonstrate the long-term consequences of early childhood trauma. These childhood experiences create a kind of long-term programming that has a negative effect in adulthood. From his psychoneuroimmunological perspective, Rainer Straub identifies four factors that link the brain to the immune system and are involved in chronic immune activation: direct connectors originating in the brain, indirect connectors functioning through hormonal and neuronal pathways, extracorporeal (the environmental factors) and pleiotropic (genetic factors) connectors. The author Prof. Rainer H. Straub, MD, is Professor of Experimental Medicine and is rheumatologist. He heads the Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine at the University Hospital Regensburg. His nonfiction books "Understanding Aging, Fatigue, and Inflammation" (2018) and "Three Memories for the Body" (2020) have been published by Springer. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content.

Early Trauma as the Origin of Chronic Inflammation

Author : Rainer H. Straub
Publisher : Springer Nature
ISBN 13 : 3662667517
Total Pages : 267 pages
Book Rating : 4.6/5 (626 download)

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Book Synopsis Early Trauma as the Origin of Chronic Inflammation by : Rainer H. Straub

Download or read book Early Trauma as the Origin of Chronic Inflammation written by Rainer H. Straub and published by Springer Nature. This book was released on 2023-02-02 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to sensitize physicians and researchers to the important long-term health effects of early, persistent, and severe trauma. The author, an internist, rheumatologist, and basic researcher in psychoneuroimmunology, shows connections between adverse childhood experiences and typical adult sequelae. After early traumatic experiences and childhood stress, there is a higher incidence of mental illness, chronic pain, sleep disorders, dental problems, obesity, cardiovascular disease, asthma, diabetes mellitus and chronic inflammation. A selection of diseases unmistakably demonstrate the long-term consequences of early childhood trauma. These childhood experiences create a kind of long-term programming that has a negative effect in adulthood. From his psychoneuroimmunological perspective, Rainer Straub identifies four factors that link the brain to the immune system and are involved in chronic immune activation: direct connectors originating from the brain, indirect connectors functioning through hormonal and neuronal pathways, extracorporeal (the environmental factors) and pleiotropic connectors (genetic factors). The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content.

PTSD Research Quarterly

Author :
Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis PTSD Research Quarterly by :

Download or read book PTSD Research Quarterly written by and published by . This book was released on 1991 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Oxford Handbook of Psychoneuroimmunology

Author : Suzanne Segerstrom
Publisher : Oxford University Press
ISBN 13 : 0195394399
Total Pages : 523 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis The Oxford Handbook of Psychoneuroimmunology by : Suzanne Segerstrom

Download or read book The Oxford Handbook of Psychoneuroimmunology written by Suzanne Segerstrom and published by Oxford University Press. This book was released on 2012-07-19 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collects the state-of-the-art applications of psychological theory to the interactions among the mind, the nervous system, and the immune system, including applications drawn from affective science, developmental psychology, behavioral neuroscience, and clinical psychology.

Fundamentals of Inflammation

Author : Charles N. Serhan
Publisher : Cambridge University Press
ISBN 13 : 1139936670
Total Pages : 489 pages
Book Rating : 4.1/5 (399 download)

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Book Synopsis Fundamentals of Inflammation by : Charles N. Serhan

Download or read book Fundamentals of Inflammation written by Charles N. Serhan and published by Cambridge University Press. This book was released on 2010-04-26 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, medical scientists, and researchers from other disciplines wishing to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.

The Deepest Well

Author : Nadine Burke Harris
Publisher : Houghton Mifflin Harcourt
ISBN 13 : 0544828704
Total Pages : 273 pages
Book Rating : 4.5/5 (448 download)

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Book Synopsis The Deepest Well by : Nadine Burke Harris

Download or read book The Deepest Well written by Nadine Burke Harris and published by Houghton Mifflin Harcourt. This book was released on 2018 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pioneering physician reveals how childhood stress leads to lifelong health problems, and what we can do to break the cycle.

The Body Keeps the Score

Author : Bessel A. Van der Kolk
Publisher : Penguin Books
ISBN 13 : 0143127748
Total Pages : 466 pages
Book Rating : 4.1/5 (431 download)

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Book Synopsis The Body Keeps the Score by : Bessel A. Van der Kolk

Download or read book The Body Keeps the Score written by Bessel A. Van der Kolk and published by Penguin Books. This book was released on 2015-09-08 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published by Viking Penguin, 2014.

The Myth of Normal

Author : Gabor Maté, MD
Publisher : Penguin
ISBN 13 : 059308389X
Total Pages : 560 pages
Book Rating : 4.5/5 (93 download)

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Book Synopsis The Myth of Normal by : Gabor Maté, MD

Download or read book The Myth of Normal written by Gabor Maté, MD and published by Penguin. This book was released on 2022-09-13 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times bestseller By the acclaimed author of In the Realm of Hungry Ghosts, a groundbreaking investigation into the causes of illness, a bracing critique of how our society breeds disease, and a pathway to health and healing. In this revolutionary book, renowned physician Gabor Maté eloquently dissects how in Western countries that pride themselves on their healthcare systems, chronic illness and general ill health are on the rise. Nearly 70 percent of Americans are on at least one prescription drug; more than half take two. In Canada, every fifth person has high blood pressure. In Europe, hypertension is diagnosed in more than 30 percent of the population. And everywhere, adolescent mental illness is on the rise. So what is really “normal” when it comes to health? Over four decades of clinical experience, Maté has come to recognize the prevailing understanding of “normal” as false, neglecting the roles that trauma and stress, and the pressures of modern-day living, exert on our bodies and our minds at the expense of good health. For all our expertise and technological sophistication, Western medicine often fails to treat the whole person, ignoring how today’s culture stresses the body, burdens the immune system, and undermines emotional balance. Now Maté brings his perspective to the great untangling of common myths about what makes us sick, connects the dots between the maladies of individuals and the declining soundness of society—and offers a compassionate guide for health and healing. Cowritten with his son Daniel, The Myth Of Normal is Maté’s most ambitious and urgent book yet.

Tender Paws

Author : Wendy Lyons Sunshine
Publisher : Simon and Schuster
ISBN 13 : 0757324959
Total Pages : 352 pages
Book Rating : 4.7/5 (573 download)

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Book Synopsis Tender Paws by : Wendy Lyons Sunshine

Download or read book Tender Paws written by Wendy Lyons Sunshine and published by Simon and Schuster. This book was released on 2024-05-28 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tender Paws takes a deep dive into the practical benefits of applying therapeutic parenting best practices to dogs in our care. When Wendy Lyons Sunshine got her first puppy—abandoned behind a gas station, struggling with worms and anemia—she was in over her head. As puppy training guides failed to help her with the out-of-control, traumatized bundle of teeth and claws rescue pup, she turned to her work helping world-class child development experts. Could strategies for raising happy, well-adjusted kids transfer to a puppy? As it turns out, yes, they can! From the first try, parenting wisdom transformed Sunshine’s relationship with her challenging little one. Soon enough, Sunshine’s view of her puppy shifted from one of adversity to one of compassion and understanding, and she was able to bring patience and therapeutic concepts to meet her dog’s needs. When Sunshine reached out to experts, they affirmed that science-based principles used with at-risk children align well with best practices of holistic, positive, and progressive dog handling. Exploring parallels between human and canine research, attachment styles, history of trauma, parenting styles, and her own “inner child” proved a mindful path for pet parenting. Far from a standard dog training manual, Tender Paws explicitly applies parenting wisdom and best practices used with special needs kids to a cross-section of scenarios, from recognizing developmental trauma and unmet core needs, to making decisions about appropriate equipment, to responding to difficult behavior, to understanding the parenting style from which we approach our dogs. Sunshine empowers you and your dog by offering: A synthesis of the fields of child development, attachment, trauma, sensory integration, neurobiology, learning, animal behavior, and ethology. A problem-solving framework that makes dog training decisions clearer and behavior frustrations easier to resolve. Parenting wisdom to help your dog move beyond trauma and into wellness. Borrowing the principles of parenting for dogs feels obvious to some people: instinctive and ordinary and inevitable. But that’s not true for everyone, especially those of us who had a less than ideal childhood and bear the scars of early harm, loss, trauma, or deprivation. Tender Paws provides an interdisciplinary, comprehensive, evidence-based guide for readers who want to honor the needs of—and improve outcomes for—puppies and dogs they care about.

Understanding Aging, Fatigue, and Inflammation

Author : Rainer H. Straub
Publisher : Springer Nature
ISBN 13 : 3662689049
Total Pages : 211 pages
Book Rating : 4.6/5 (626 download)

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Book Synopsis Understanding Aging, Fatigue, and Inflammation by : Rainer H. Straub

Download or read book Understanding Aging, Fatigue, and Inflammation written by Rainer H. Straub and published by Springer Nature. This book was released on with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Inflammation and Cancer

Author : Bharat B. Aggarwal
Publisher : Springer
ISBN 13 : 3034808372
Total Pages : 489 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Inflammation and Cancer by : Bharat B. Aggarwal

Download or read book Inflammation and Cancer written by Bharat B. Aggarwal and published by Springer. This book was released on 2014-05-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Inflammation-Associated Depression: Evidence, Mechanisms and Implications

Author : Robert Dantzer
Publisher : Springer
ISBN 13 : 3319511521
Total Pages : 357 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Inflammation-Associated Depression: Evidence, Mechanisms and Implications by : Robert Dantzer

Download or read book Inflammation-Associated Depression: Evidence, Mechanisms and Implications written by Robert Dantzer and published by Springer. This book was released on 2016-12-28 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.

Adverse Childhood Experiences

Author : Gordon G. J. G. Asmundson
Publisher : Academic Press
ISBN 13 : 0128160667
Total Pages : 384 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Adverse Childhood Experiences by : Gordon G. J. G. Asmundson

Download or read book Adverse Childhood Experiences written by Gordon G. J. G. Asmundson and published by Academic Press. This book was released on 2019-10-03 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse Childhood Experiences: Using Evidence to Advance Research, Practice, Policy, and Prevention defines ACEs, provides a summary of the past 20 years of ACEs research, as well as provides guidance for the future directions for the field. It includes a review of the original ACEs Study, definitions of ACEs, and how ACEs are typically assessed. Other content includes a review of how ACEs are related to mental and physical health outcome, the neurodevelopmental mechanisms linking ACEs to psychopathology, sexual violence and sexual health outcomes, and violence across the lifespan. Important and contemporary issues in the field, like reconsidering how ACEs should be defined and assessed, the appropriateness of routine ACEs screening, thinking about ACEs from a public health and global perspective, strategies for preventing ACEs, understanding ACEs and trauma-informed care and resilience, and the importance of safe stable and nurturing environments for children are discussed. Adverse Childhood Experiences is a useful evidence-based resource for professionals working with children and families, including physicians, nurses, social workers, psychologists, lawyers, judges, as well as public health leaders, policy makers, and government delegates. Reviews the past 20 years of ACEs research Examines ACEs and mental and physical health Discusses the neurodevelopment mechanisms of ACEs and psychopathology Examines ACEs and violence across the lifespan Reconsiders the definition and assessment of ACEs Examines the issue of routine ACEs screening Discusses ACEs from a public health and global perspective Summarizes effective ACEs prevention, trauma-informed care, and resilience Provides recommendations for the future directions of the ACEs field

Mitochondrial Dysfunction

Author : Lawrence H. Lash
Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash

Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Inflamed

Author : Rupa Marya
Publisher : Farrar, Straus and Giroux
ISBN 13 : 0374602522
Total Pages : 496 pages
Book Rating : 4.3/5 (746 download)

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Book Synopsis Inflamed by : Rupa Marya

Download or read book Inflamed written by Rupa Marya and published by Farrar, Straus and Giroux. This book was released on 2021-08-03 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Raj Patel, the New York Times bestselling author of The Value of Nothing, teams up with physician, activist, and co-founder of the Do No Harm Coalition Rupa Marya to reveal the links between health and structural injustices--and to offer a new deep medicine that can heal our bodies and our world. The Covid pandemic and the shocking racial disparities in its impact. The surge in inflammatory illnesses such as gastrointestinal disorders and asthma. Mass uprisings around the world in response to systemic racism and violence. Rising numbers of climate refugees. Our bodies, societies, and planet are inflamed. Boldly original, Inflamed takes us on a medical tour through the human body—our digestive, endocrine, circulatory, respiratory, reproductive, immune, and nervous systems. Unlike a traditional anatomy book, this groundbreaking work illuminates the hidden relationships between our biological systems and the profound injustices of our political and economic systems. Inflammation is connected to the food we eat, the air we breathe, and the diversity of the microbes living inside us, which regulate everything from our brain’s development to our immune system’s functioning. It’s connected to the number of traumatic events we experienced as children and to the traumas endured by our ancestors. It’s connected not only to access to health care but to the very models of health that physicians practice. Raj Patel, the renowned political economist and New York Times bestselling author of The Value of Nothing, teams up with the physician Rupa Marya to offer a radical new cure: the deep medicine of decolonization. Decolonizing heals what has been divided, reestablishing our relationships with the Earth and one another. Combining the latest scientific research and scholarship on globalization with the stories of Marya’s work with patients in marginalized communities, activist passion, and the wisdom of Indigenous groups, Inflamed points the way toward a deep medicine that has the potential to heal not only our bodies, but the world.

The Resolution of Inflammation

Author : Adriano Rossi
Publisher : Springer Science & Business Media
ISBN 13 : 376437506X
Total Pages : 246 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis The Resolution of Inflammation by : Adriano Rossi

Download or read book The Resolution of Inflammation written by Adriano Rossi and published by Springer Science & Business Media. This book was released on 2008-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.

Mechanisms of Vascular Disease

Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.