The Neurobiology of Aging and Alzheimer Disease in Down Syndrome

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Author :
Publisher : Academic Press
ISBN 13 : 0128188464
Total Pages : 354 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Neurobiology of Aging and Alzheimer Disease in Down Syndrome by : Elizabeth Head

Download or read book The Neurobiology of Aging and Alzheimer Disease in Down Syndrome written by Elizabeth Head and published by Academic Press. This book was released on 2021-08-31 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. - Discusses the complexities involved with aging and Alzheimer's disease in Down syndrome - Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age - Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research

Down Syndrome and Alzheimer's Disease

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Author :
Publisher : Radcliffe Publishing
ISBN 13 : 9781857756371
Total Pages : 206 pages
Book Rating : 4.7/5 (563 download)

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Book Synopsis Down Syndrome and Alzheimer's Disease by : Vee P. Prasher

Download or read book Down Syndrome and Alzheimer's Disease written by Vee P. Prasher and published by Radcliffe Publishing. This book was released on 2006 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the underlying biological abnormalities of Dementia in Alzheimer's Disease (DAD) in people with Down syndrome. Brings together recent research findings relating to the neuropathology, genetics, blood markers and neurophysiology of Alzheimer's disease in older adults with Down syndrome.

Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1848002491
Total Pages : 222 pages
Book Rating : 4.8/5 (48 download)

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Book Synopsis Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities by : Vee P. Prasher

Download or read book Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities written by Vee P. Prasher and published by Springer Science & Business Media. This book was released on 2009-04-29 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews important neuropsychological measures currently used in the assessment of dementia by the principal clinicians and researchers associated with the test, offering practical guidance on each test along with an analysis of its limitations.

Down Syndrome and Dementia: A Guide for Family Members, Social and Health Care Staff and Students

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Author :
Publisher : Sharing Good Practice
ISBN 13 : 9781789631678
Total Pages : 86 pages
Book Rating : 4.6/5 (316 download)

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Book Synopsis Down Syndrome and Dementia: A Guide for Family Members, Social and Health Care Staff and Students by : Bob Dawson

Download or read book Down Syndrome and Dementia: A Guide for Family Members, Social and Health Care Staff and Students written by Bob Dawson and published by Sharing Good Practice. This book was released on 2020-10-30 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide for carers who are supporting people with Down Syndrome who develop dementia.

Intellectual Disabilities and Dementia

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Author :
Publisher : Jessica Kingsley Publishers
ISBN 13 : 1784501840
Total Pages : 122 pages
Book Rating : 4.7/5 (845 download)

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Book Synopsis Intellectual Disabilities and Dementia by : Karen Watchman

Download or read book Intellectual Disabilities and Dementia written by Karen Watchman and published by Jessica Kingsley Publishers. This book was released on 2017-03-21 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected for Reading Well for Dementia 2024: endorsed by health experts, charities and people affected by dementia. Drawing on the author's first-hand experiences with families, this book provides crucial, accessible information and answers the difficult questions that often arise when a family member with an intellectual disability is diagnosed with dementia. Linking directly to policy and practice in both dementia and intellectual disability care, this book takes an outcome-focussed approach to support short, medium and long-term planning. With a particular emphasis on communication, the author seeks to ensure that families and organisations are able to converse effectively about a relative's health and care. The book looks at how to recognise when changes in the health of a relative with an intellectual disability could indicate the onset of dementia, as well as addressing common concerns surrounding living situations, medication and care plans. Each chapter is structured to identify strategies for support whilst working towards outcomes identified by families as dementia progresses.

Alzheimer's Disease and Dementia in Down Syndrome and Intellectual Disabilities

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Author :
Publisher : Radcliffe Publishing
ISBN 13 : 9781857756081
Total Pages : 164 pages
Book Rating : 4.7/5 (56 download)

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Book Synopsis Alzheimer's Disease and Dementia in Down Syndrome and Intellectual Disabilities by : Vee P. Prasher

Download or read book Alzheimer's Disease and Dementia in Down Syndrome and Intellectual Disabilities written by Vee P. Prasher and published by Radcliffe Publishing. This book was released on 2005 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic aim of this book is to help carers and professionals living or working with adults with intellectual disability to understand further Alzheimer's disease and other forms of dementia.

Down's Syndrome and Dementia

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Author :
Publisher :
ISBN 13 : 9781905218080
Total Pages : 136 pages
Book Rating : 4.2/5 (18 download)

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Book Synopsis Down's Syndrome and Dementia by : Karen Dodd

Download or read book Down's Syndrome and Dementia written by Karen Dodd and published by . This book was released on 2009 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: A resource book for family carers, staff and other professionals to help them care more effectively for people with Down's syndrome and dementia.

Down Syndrome

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9781909962477
Total Pages : 0 pages
Book Rating : 4.9/5 (624 download)

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Book Synopsis Down Syndrome by : Richard W. Newton

Download or read book Down Syndrome written by Richard W. Newton and published by John Wiley & Sons. This book was released on 2015-05-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Down syndrome remains the most common recognisable form of intellectual disability. The challenge for doctors today is how to capture the rapidly expanding body of scientific knowledge and devise models of care to meet the needs of individuals and their families. Down syndrome; Clinical Perspectives provides doctors and other health professionals with the information they need to address the challenges that can present in the management of syndrome. Chapters written by internationally respected paediatricians with a special interest in Down syndrome, cover Down syndrome comorbidities, such hearing problems, gastrointestinal disorders, congenital heart diseases, as well as the underlying biology and new developments in molecular genetics. Contributions from the UK Down Syndrome Association and Down Syndrome Medical Interest Group define how doctors can work effectively with other professionals to improve health care provisions for this group. Each chapter is illustrated by informative case scenarios and answers to FAQs from parents and carers.

CAMDEX-DS

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521547949
Total Pages : 130 pages
Book Rating : 4.5/5 (479 download)

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Book Synopsis CAMDEX-DS by : Sarah Ball

Download or read book CAMDEX-DS written by Sarah Ball and published by Cambridge University Press. This book was released on 2006-07-06 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: CAMDEX-DS is a comprehensive assessment tool for diagnosing dementia in people with Down's syndrome (a group known to be at particular risk of dementia). Based upon CAMDEX-R, CAMDEX-DS has been modified for use with intellectual disability. In order to differentiate decline due to dementia or other mental disorders from pre-existing impairment, particular emphasis has been placed on establishing change from the individual's best level of functioning. The pack is comprised of a structured informant interview, a direct assessment of the patient/participant (CAMCOG), and guidance for diagnosis and post-diagnosis intervention, providing a reliable way to identify dementia (and to differentiate it from other common disorders). It may be used in community settings by mental health professionals as part of the diagnostic process, or to formalize diagnosis in the context of research. Use of the CAMCOG provides the means for ongoing neuropsychological evaluation and informs future support and intervention strategies.

Intellectual Disability and Dementia

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Author :
Publisher : Jessica Kingsley Publishers
ISBN 13 : 0857007963
Total Pages : 338 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Intellectual Disability and Dementia by : Karen Watchman

Download or read book Intellectual Disability and Dementia written by Karen Watchman and published by Jessica Kingsley Publishers. This book was released on 2014-05-21 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting the most up-to-date information available about dementia and intellectual disabilities, this book brings together the latest international research and evidence-based practice, and describes clearly the relevance and implications for support and services Internationally renowned experts from the UK, Ireland, the USA, Canada, Australia and the Netherlands discuss good practice and the way forward in relation to assessment, diagnosis, interventions, staff knowledge and training, care pathways, service design, measuring outcomes and the experiences of individuals, families and carers. The wealth of information offered will inform support and services throughout the whole course of dementia, from diagnosis to end of life. Particular emphasis is placed on how intellectual disability and dementia services can work collaboratively to offer more effective, joined up support. Practitioners, managers and commissioners will find this to be an informative resource for developing person-centred provision for people with intellectual disabilities and dementia and their families. It will also be a key text for academics and students who wish to be up-to-date with the latest research and practice developments in this field.

Viruses: Essential Agents of Life

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Publisher : Springer Science & Business Media
ISBN 13 : 940074899X
Total Pages : 432 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Viruses: Essential Agents of Life by : Günther Witzany

Download or read book Viruses: Essential Agents of Life written by Günther Witzany and published by Springer Science & Business Media. This book was released on 2012-11-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.

Dementia and Aging Adults with Intellectual Disabilities

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Author :
Publisher : Routledge
ISBN 13 : 1317823818
Total Pages : 534 pages
Book Rating : 4.3/5 (178 download)

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Book Synopsis Dementia and Aging Adults with Intellectual Disabilities by : Matthew P. Janicki

Download or read book Dementia and Aging Adults with Intellectual Disabilities written by Matthew P. Janicki and published by Routledge. This book was released on 2014-04-23 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: This definitive handbook assembles the most recent advances in knowledge about dementia, Alzheimer Disease, and related disorders as they affect persons with intellectual disabilities. Diagnosis, assessment, treatment, and management and care practices are detailed in a practical manner making this a useful tool to both students and trained professionals. After an introduction to the subject, the book begins with persoanl accounts of three affected individuals whose signs of dementia are described from clinical, family member, and care-provider perspectives, respectively. The biology and physiology of dementia, as well as the neurological and medical complications associated with it, are then provided in Parts Two, three, and Four. The application and practical perspectives of this handbook are enhanced in Part Five which details the best practices available to meet the needs and challenges involved in care and quality of life issues. The challenge raised by the rapidly growing number of aging individuals with intellectual disabilities forms the basis for the final part of the volume, an analysis and presentation of rarely addressed policy issues. Extensive resource information and a comprehensive glossary contribute to the useful nature of this handbook. Practitioners, service providers, educators and students will benefit from the accessability and practicality if this text as well as the breadth and depth of knowledge of the editors and contributors.

Intellectual Disabilities in Down Syndrome from Birth and throughout Life: Assessment and Treatment

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889450457
Total Pages : 183 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Intellectual Disabilities in Down Syndrome from Birth and throughout Life: Assessment and Treatment by : Marie-Claude Potier

Download or read book Intellectual Disabilities in Down Syndrome from Birth and throughout Life: Assessment and Treatment written by Marie-Claude Potier and published by Frontiers Media SA. This book was released on 2017-02-24 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on the multiple aspects of cognitive impairment in Down syndrome (DS), from genes to behavior to treatment, has made tremendous progress in the last decade. The study of congenital intellectual disabilities such as DS is challenging since they originate from the earliest stages of development and both the acquisition of cognitive skills and neurodegenerative pathologies are cumulative. Comorbidities such as cardiac malformations, sleep apnea, diabetes and dementia are frequent in the DS population, as well, and their increased risk provides a means of assessing early stages of these pathologies that is relevant to the general population. Notably, persons with DS will develop the histopathology of Alzheimer’s disease (formation of neuritic plaques and tangles) and are at high risk for dementia, something that cannot be predicted in the population at large. Identification of the gene encoding the amyloid precursor protein, its localization to chromosome 21 in the 90’s and realization that all persons with DS develop pathology identified this as an important piece of the amyloid cascade hypothesis in Alzheimer’s disease. Awareness of the potential role of people with DS in understanding progression and treatment as well as identification of genetic risk factors and also protective factors for AD is reawakening. For the first time since DS was recognized, major pharmaceutical companies have entered the search for ameliorative treatments, and phase II clinical trials to improve learning and memory are in progress. Enriched environment, brain stimulation and alternative therapies are being tested while clinical assessment is improving, thus increasing the chances of success for therapeutic interventions. Researchers and clinicians are actively pursuing the possibility of prenatal treatments for many conditions, an area with a huge potential impact for developmental disorders such as DS. Our goal here is to present an overview of recent advances with an emphasis on behavioral and cognitive deficits and how these issues change through life in DS. The relevance of comorbidities to the end phenotypes described and relevance of pharmacological targets and possible treatments will be considerations throughout.

Alzheimer’s Disease

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Alzheimer’s Disease by : Harvey J. Altman

Download or read book Alzheimer’s Disease written by Harvey J. Altman and published by Springer. This book was released on 1987-12-31 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Proceedings of a National Conference on Alzheimer's Disease and Dementia: problems, prospects, and perspectives, held April 10-12, 1986, in Detroit, Michigan" - T.p. verso.

The Neuropathology of Dementia

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Publisher : Cambridge University Press
ISBN 13 : 9780521819152
Total Pages : 600 pages
Book Rating : 4.8/5 (191 download)

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Book Synopsis The Neuropathology of Dementia by : Margaret M. Esiri

Download or read book The Neuropathology of Dementia written by Margaret M. Esiri and published by Cambridge University Press. This book was released on 2004-07-22 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.

Paul's Story

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Author :
Publisher : Christian Faith Publishing, Inc.
ISBN 13 : 1098099729
Total Pages : 62 pages
Book Rating : 4.0/5 (98 download)

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Book Synopsis Paul's Story by : Lorraine DeForge

Download or read book Paul's Story written by Lorraine DeForge and published by Christian Faith Publishing, Inc.. This book was released on 2022-02-22 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: I decided to write this book because I wanted people to know that having a baby with Down syndrome is not the end of the world. Paul's start in life was very scary, my pregnancy was difficult, and he was born premature. We weren't given much hope for his survival, or that he would have any kind of life if he did, but we wanted him to be with us for however long that would be. He ended up having a very productive life. He worked, learned to use public transportation, moved into a supervised apartment, and was married to his Down syndrome wife for twenty-five years before he passed away. This book is about how Paul was truly a special gift to his dad, myself, and all his brothers and sisters.

Understanding Learning Disability and Dementia

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Author :
Publisher : Jessica Kingsley Publishers
ISBN 13 : 1843104423
Total Pages : 202 pages
Book Rating : 4.8/5 (431 download)

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Book Synopsis Understanding Learning Disability and Dementia by : Diana Kerr

Download or read book Understanding Learning Disability and Dementia written by Diana Kerr and published by Jessica Kingsley Publishers. This book was released on 2007 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all the essential issues in supporting a person with a learning disability when they develop dementia.