Disorders of Hemostasis & Thrombosis: A Clinical Guide, Second Edition

Download Disorders of Hemostasis & Thrombosis: A Clinical Guide, Second Edition PDF Online Free

Author :
Publisher : McGraw Hill Professional
ISBN 13 : 9780071348348
Total Pages : 652 pages
Book Rating : 4.3/5 (483 download)

DOWNLOAD NOW!


Book Synopsis Disorders of Hemostasis & Thrombosis: A Clinical Guide, Second Edition by : Scott H. Goodnight

Download or read book Disorders of Hemostasis & Thrombosis: A Clinical Guide, Second Edition written by Scott H. Goodnight and published by McGraw Hill Professional. This book was released on 2001 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now expanded with new coverage of genetics, more therapy and management strategies, and more references throughout, this guide remains one of the most practical resources for diagnosis and treatment of hematologic conditions commonly seen in general practice. The clear, succinct language is meant for the non-hematologist who wants the salient points of clinical signs, etiology and pathophysiology, laboratory tests, differential diagnosis, and treatment in one convenient manual.

Essential Guide to Blood Coagulation

Download Essential Guide to Blood Coagulation PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1444357662
Total Pages : 153 pages
Book Rating : 4.4/5 (443 download)

DOWNLOAD NOW!


Book Synopsis Essential Guide to Blood Coagulation by : Margareta Blombäck

Download or read book Essential Guide to Blood Coagulation written by Margareta Blombäck and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to laboratory diagnosis and treatment of hemostatic disorders. This concise book covers all you need to know to manage thrombotic and bleeding disorders, distilling the most clinically up-to-date information, and including the latest treatment strategies for key conditions and diseases. Essential Guide to Blood Coagulation covers both the stable and the acute stages of hereditary and acquired bleeding and thrombotic disorders. Faced with a bleeding patient, it may be difficult to determine whether blood loss is due to a local factor or an underlying hemostatic defect. There are a range of laboratory tests which can be performed to identify the cause of bleeding in a patient. This book highlights the tests that can be used in the laboratory to aid diagnosis. Originally published in Swedish, Essential Guide to Blood Coagulation, has been revised to include the latest treatment strategies available for patients and will help clinicians to expand their knowledge of hemostatic disorders.

Quality in Laboratory Hemostasis and Thrombosis

Download Quality in Laboratory Hemostasis and Thrombosis PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1444360590
Total Pages : 325 pages
Book Rating : 4.4/5 (443 download)

DOWNLOAD NOW!


Book Synopsis Quality in Laboratory Hemostasis and Thrombosis by : Steve Kitchen

Download or read book Quality in Laboratory Hemostasis and Thrombosis written by Steve Kitchen and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Over the last decades, major progress has been made in quality assurance of hemostatic laboratory assays. This book will be an indispensable part of every hemostasis laboratory, where, given its hands-on nature, it will rarely sit to get dusty on the shelves." —Frits R. Rosendaal, Leiden University Medical Center The hemostasis laboratory has a vital role in the diagnosis and management of patients with familial and acquired hemorrhagic and thrombotic disorders. Its role in the monitoring traditional anticoagulant therapy as well as therapy using new anticoagulants presents new challenges to the laboratory. Quality in Laboratory Hemostasis and Thrombosis not only addresses these important issues, but also covers international guidelines for testing, the development of international standard materials, management of hemostasis testing from the laboratory to the point of care as well as molecular genetic testing. Designed as a guide for all those working in hemostasis laboratories, this book details a quality program that, when put into place, will help to improve standards in testing. All of the authors are internationally recognised for their work in hemostasis and thrombosis. Using their experience, they provide information on standards, equipment and methods that will guide the development of a quality program to support all activities in the hemostasis laboratory.

Disorders of Hemostasis & Thrombosis: A Clinical Guide, Second Edition

Download Disorders of Hemostasis & Thrombosis: A Clinical Guide, Second Edition PDF Online Free

Author :
Publisher : McGraw-Hill Education / Medical
ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Disorders of Hemostasis & Thrombosis: A Clinical Guide, Second Edition by : Scott H. Goodnight

Download or read book Disorders of Hemostasis & Thrombosis: A Clinical Guide, Second Edition written by Scott H. Goodnight and published by McGraw-Hill Education / Medical. This book was released on 2001 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now expanded with new coverage of genetics, more therapy and management strategies, and more references throughout, this guide remains one of the most practical resources for diagnosis and treatment of hematologic conditions commonly seen in general practice. The clear, succinct language is meant for the non-hematologist who wants the salient points of clinical signs, etiology and pathophysiology, laboratory tests, differential diagnosis, and treatment in one convenient manual.

Hemostasis and Thrombosis

Download Hemostasis and Thrombosis PDF Online Free

Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451177690
Total Pages : 5220 pages
Book Rating : 4.4/5 (511 download)

DOWNLOAD NOW!


Book Synopsis Hemostasis and Thrombosis by : Victor J. Marder

Download or read book Hemostasis and Thrombosis written by Victor J. Marder and published by Lippincott Williams & Wilkins. This book was released on 2012-12-27 with total page 5220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of both basic scientists and clinicians. This comprehensive resource details the essentials of bleeding and thrombotic disorders and the management of patients with these and related problems, and delivers the most up-to-date information on normal biochemistry and function of platelets or endothelial cells, as well as in-depth discussions of the pharmacology of anticoagulant, fibrinolytic, and hemostatic drugs. NEW to the Sixth Edition... • A new team of editors, each a leader in his field, assures you of fresh, authoritative perspectives. • Full color throughout • A companion website that offers full text online and an image bank. • A new introductory section of chapters on basic sciences as related to the field • Entirely new section on Hemostatic and Thrombotic Disorders Associated with Systemic Conditions includes material on pediatric patients, women's health issues, cancer, sickle cell disease, and other groups. • Overview chapters preceding each section address broad topics of general importance. This is the tablet version which does not include access to the supplemental content mentioned in the text.

Practical Hemostasis and Thrombosis

Download Practical Hemostasis and Thrombosis PDF Online Free

Author :
Publisher : Wiley-Blackwell
ISBN 13 : 1444306294
Total Pages : 328 pages
Book Rating : 4.4/5 (443 download)

DOWNLOAD NOW!


Book Synopsis Practical Hemostasis and Thrombosis by : Nigel Key

Download or read book Practical Hemostasis and Thrombosis written by Nigel Key and published by Wiley-Blackwell. This book was released on 2009-10-01 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide provides all the information necessary to understand the clotting mechanisms, as well as how to prevent, diagnose, and treat bleeding and clotting disorders. Practical Hemostasis and Thrombosis has been updated to reflect all the important advances made since the first edition. It includes an in-depth description of platelet abnormalities and disseminated intravascular coagulation, as well as covering the laboratory and molecular biological tests needed for the diagnosis of bleeding and clotting disorders. Clinicians will find useful advice for everyday questions in each specialty area as the book describes hemorrhagic and thrombotic problems in cardiology, neurology, hepatology, nephrology, oncology, obstetrics, pediatrics, intensive care and transfusion medicine. An invaluable resource for all hematologists, trainee hematologists preparing for examinations and clinicians this book should be kept close at hand for frequent consultation

Essential Guide to Blood Coagulation

Download Essential Guide to Blood Coagulation PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118327667
Total Pages : 168 pages
Book Rating : 4.1/5 (183 download)

DOWNLOAD NOW!


Book Synopsis Essential Guide to Blood Coagulation by : Jovan P. Antovic

Download or read book Essential Guide to Blood Coagulation written by Jovan P. Antovic and published by John Wiley & Sons. This book was released on 2013-03-11 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to laboratory diagnosis and treatment of hemostatic disorders. This concise book distils the most clinically up-to-date information on thrombotic and bleeding disorders, including the latest treatment strategies, for key conditions and diseases. Essential Guide to Blood Coagulation covers both the stable and the acute stages of hereditary and acquired bleeding and thrombotic disorders. Faced with a bleeding patient, it may be difficult to determine whether blood loss is due to a local factor, or an underlying hemostatic defect. There are a range of laboratory tests which can be performed to identify the cause of bleeding in a patient. This book highlights the tests that can be used in the laboratory to aid diagnosis. Essential Guide to Blood Coagulation has been updated to include the new anticoagulants and now has a dedicated chapter on antiplatelet drugs. This invaluable guide will help all those treating patients to expand their knowledge of hemostatic disorders. TITLES OF RELATED INTEREST Hemophilia and Hemostasis: A Case-Based Approach to Management Second Edition Alice Ma, Harold Roberts, Miguel Escobar ISBN: 978-0-470-65976-2 Quality in Laboratory Hemostasis and Thrombosis Second Edition Steve Kitchen, John Olson, Eric Preston (due May 2013) ISBN: 978-0-470-67119-1

Pathophysiology of Blood Disorders

Download Pathophysiology of Blood Disorders PDF Online Free

Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071713786
Total Pages : 354 pages
Book Rating : 4.0/5 (717 download)

DOWNLOAD NOW!


Book Synopsis Pathophysiology of Blood Disorders by : Howard Franklin Bunn

Download or read book Pathophysiology of Blood Disorders written by Howard Franklin Bunn and published by McGraw Hill Professional. This book was released on 2010-12-27 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise full-color review of the mechanisms of blood diseases and disorders – based on a Harvard Medical School hematology course 4 STAR DOODY'S REVIEW! "This is a superb book. Deceptively small, yet packs a wallop. The emphasis on principles instead of practice is welcome....The text is clear, concise, and surprisingly approachable for what could have been a very dense and dry discussion. I could not put this book down and read it entirely in one sitting. When was the last time anyone found a hematology textbook so riveting?"--Doody's Review Service Hematological Pathophysiology is a well-illustrated, easy-to-absorb introduction to the physiological principles underlying the regulation and function of blood cells and hemostasis, as well as the pathophysiologic mechanisms responsible for the development of blood disorders. Featuring a strong emphasis on key principles, the book covers diagnosis and management primarily within a framework of pathogenesis. Authored by world-renowned clinician/educators at Harvard Medical School, Hematological Pathophysiology features content and organization based on a hematology course offered to second year students at that school. The book is logically divided into four sections: Anemias and Disorders of the Red Blood Cell, Disorders of Hemostasis and Thrombosis, Disorders of Leukocytes, and Transfusion Medicine; it opens with an important overview of blood and hematopoietic tissues. Features Succinct, to-the-point coverage that reflects current medical education More than 200 full-color photographs and renderings of disease mechanisms and blood diseases Each chapter includes learning objectives and self-assessment questions Numerous tables and diagrams encapsulate important information Incorporates the feedback of 180 Harvard medical students who reviewed the first draft -- so you know you’re studying the most relevant material possible

Consultative Hemostasis and Thrombosis E-Book

Download Consultative Hemostasis and Thrombosis E-Book PDF Online Free

Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455733296
Total Pages : 843 pages
Book Rating : 4.4/5 (557 download)

DOWNLOAD NOW!


Book Synopsis Consultative Hemostasis and Thrombosis E-Book by : Craig S. Kitchens

Download or read book Consultative Hemostasis and Thrombosis E-Book written by Craig S. Kitchens and published by Elsevier Health Sciences. This book was released on 2013-02-20 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.

Laboratory Hemostasis

Download Laboratory Hemostasis PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319089242
Total Pages : 210 pages
Book Rating : 4.3/5 (19 download)

DOWNLOAD NOW!


Book Synopsis Laboratory Hemostasis by : Sterling T. Bennett

Download or read book Laboratory Hemostasis written by Sterling T. Bennett and published by Springer. This book was released on 2014-10-14 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coagulation testing is the basis for the diagnosis of bleeding and thrombotic disorders, as well as the mainstay of anticoagulant monitoring and management. This handbook provides practical information and guidance on topics relevant to directing a coagulation laboratory, filling a void in the literature. Since the first edition, all chapters have been updated and an entirely new chapter is included on pharmacogenomics and pharmacogenetics. The book will aid pathologists, clinical laboratory scientists and other physicians serving as laboratory directors to understand and carry out their responsibilities. It will also assist residents and fellows in learning the basics of coagulation testing and serve as a useful day-to-day reference for coagulation laboratory supervisors, technologists, and technicians. Finally, clinicians may find aspects of the book helpful in understanding the role of the coagulation laboratory in patient evaluation and monitoring.

Hemophilia and Hemostasis

Download Hemophilia and Hemostasis PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118439309
Total Pages : 245 pages
Book Rating : 4.1/5 (184 download)

DOWNLOAD NOW!


Book Synopsis Hemophilia and Hemostasis by : Alice D. Ma

Download or read book Hemophilia and Hemostasis written by Alice D. Ma and published by John Wiley & Sons. This book was released on 2012-10-03 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a general need amongst healthcare professionals for practical advice on the management of patients with bleeding disorders. This book is an essential resource for all those working in the fields of coagulation, hemostasis and thrombosis. It covers the major cases one might encounter in diagnosing, managing and treating hemophilia and hemostasis. It provides a practical and informative guide to the broad range of topics concerning both bleeding and clotting disorders. The book is divided into major chapter sections depending on the type of bleeding disorder it fits into. Each chapter includes a brief overview of the disorder covering: history of the disorder; molecular basis of the disorder; class presentation; genetics; current laboratory tests and monitoring. Cases associated with each disorder are presented alongside practical questions and answers from a wide range of contributors. As practice can vary from center to center, controversial areas are clearly marked and discussed throughout. New to this edition: coverage of the newer techniques; newer treatment modalities; new oral anticoagulants; update on hemophilia management; more on ITP and greater coverage of new cases as suggested by reviewers.

Concise Guide to Hematology

Download Concise Guide to Hematology PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 331997873X
Total Pages : 540 pages
Book Rating : 4.3/5 (199 download)

DOWNLOAD NOW!


Book Synopsis Concise Guide to Hematology by : Hillard M. Lazarus

Download or read book Concise Guide to Hematology written by Hillard M. Lazarus and published by Springer. This book was released on 2018-11-15 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive overview of the essential concepts and malignancies of hematology. Now in its second edition, the book reviews every major hematologic disorder and disease entity in thorough detail, from incidence and prevalence to patient and treatment-related issues. Formatted in an organized and easy-to-read outline style to facilitate rapid learning and information processing, the book allows readers to easily locate topics of immediate interest without wading through entire sections to obtain the desired data. Written by a diverse range of experts in the field, Concise Guide to Hematology, Second Edition is a valuable resource for clinicians, residents, trainees, and entry-level fellows who work in or are just entering the field of hematology.

Williams Hematology Hemostasis and Thrombosis

Download Williams Hematology Hemostasis and Thrombosis PDF Online Free

Author :
Publisher : McGraw Hill Professional
ISBN 13 : 126011709X
Total Pages : 545 pages
Book Rating : 4.2/5 (61 download)

DOWNLOAD NOW!


Book Synopsis Williams Hematology Hemostasis and Thrombosis by : Kenneth Kaushansky

Download or read book Williams Hematology Hemostasis and Thrombosis written by Kenneth Kaushansky and published by McGraw Hill Professional. This book was released on 2018-01-12 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemostasis and Thrombosis as only Williams can cover them A Doody’s Core Title for 2019! Featuring content derived from Williams Hematology, Ninth Edition. this concise, full-color resource delivers comprehensive and current coverage of hemostasis and thrombosis, and platelet and megakaryocyte disorders. More than a sectional reprint, the book includes updated science and treatment recommendations not found in the 2015 release of Williams Hematology, Ninth Edition. Perfect for use at the point of care, Williams Hemostasis and Thrombosis offers the most current evaluation and treatment options for patients with bleeding and thrombotic disorders. •Covers the latest advances in hemostasis and thrombosis •A handy quick summary appears at the beginning of each chapter •Discusses the physiologic basis for hemostasis and thrombosis

Clinical Hematology and Fundamentals of Hemostasis

Download Clinical Hematology and Fundamentals of Hemostasis PDF Online Free

Author :
Publisher : Davis Publications
ISBN 13 :
Total Pages : 730 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Clinical Hematology and Fundamentals of Hemostasis by : Denise Harmening

Download or read book Clinical Hematology and Fundamentals of Hemostasis written by Denise Harmening and published by Davis Publications. This book was released on 1992 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and thorough guide to clinical hematology and the fundamentals of hemostasis. The text's five parts provide a substantial introduction to the subject, followed by sections on the anemias, white blood cell disorders, hemostasis/thrombosis, and laboratory methods. This edition includes new chapters addressing the use of flow cytometry, the molecular diagnostic techniques in hematopathology, and an introduction to thrombosis and anticoagulant therapy. A feature of previous editions, a 260-page color-plate atlas, has been incorporated throughout the text. Annotation copyright by Book News, Inc., Portland, OR

SickKids Handbook of Pediatric Thrombosis and Hemostasis

Download SickKids Handbook of Pediatric Thrombosis and Hemostasis PDF Online Free

Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318021970
Total Pages : 274 pages
Book Rating : 4.3/5 (18 download)

DOWNLOAD NOW!


Book Synopsis SickKids Handbook of Pediatric Thrombosis and Hemostasis by : Victor S. Blanchette

Download or read book SickKids Handbook of Pediatric Thrombosis and Hemostasis written by Victor S. Blanchette and published by Karger Medical and Scientific Publishers. This book was released on 2013 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: SickKids Handbook of Pediatric Thrombosis and Hemostasis takes the reader through the entire field of paediatric thrombosis and hemostasis. This practical reference book will be a convenient, comprehensive, source of information and provides up-to-date, evidence-based guidance in the diagnosis and management of inherited and acquired bleeding disorders and thrombotic events of the venous, arterial, cardiac and central nervous systems that affect children, including the neonate. Written and reviewed by international experts in the field, SickKids Handbook of Pediatric Thrombosis and Hemostasis will guide health care professionals involved in the assessment and care of children with all types of bleeding and clotting disorders, including general and specialist pediatricians, in particular intensivists, neonatologists, cardiologists/cardiac surgeons, rheumatologists and nephrologists; hematologists/oncologists as well as nurses, nurse practitioners and pharmacists. Written in a user-friendly, algorithmic approach, the resource will serve students and trainees and assist teachers in developing practical lessons.

Trauma Induced Coagulopathy

Download Trauma Induced Coagulopathy PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030536068
Total Pages : 802 pages
Book Rating : 4.0/5 (35 download)

DOWNLOAD NOW!


Book Synopsis Trauma Induced Coagulopathy by : Hunter B. Moore

Download or read book Trauma Induced Coagulopathy written by Hunter B. Moore and published by Springer Nature. This book was released on 2020-10-12 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.

The Obstetric Hematology Manual

Download The Obstetric Hematology Manual PDF Online Free

Author :
Publisher : Cambridge University Press
ISBN 13 : 1108548377
Total Pages : 362 pages
Book Rating : 4.1/5 (85 download)

DOWNLOAD NOW!


Book Synopsis The Obstetric Hematology Manual by : Sue Pavord

Download or read book The Obstetric Hematology Manual written by Sue Pavord and published by Cambridge University Press. This book was released on 2018-02-08 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.