Discovering Retroviruses

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Author :
Publisher : Harvard University Press
ISBN 13 : 0674988752
Total Pages : 193 pages
Book Rating : 4.6/5 (749 download)

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Book Synopsis Discovering Retroviruses by : Anna Marie Skalka

Download or read book Discovering Retroviruses written by Anna Marie Skalka and published by Harvard University Press. This book was released on 2018-10-15 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately eight percent of our DNA contains retroviral sequences that are millions of years old. Through engaging stories of scientific discovery, Anna Marie Skalka explains our evolving knowledge of these ancient denizens of the biosphere and how this understanding has significantly advanced research in genetic engineering, gene delivery systems, and precision medicine. Discovering Retroviruses begins with the pioneer scientists who first encountered these RNA-containing viruses and solved the mystery of their reproduction. Like other viruses, retroviruses invade the cells of a host organism to reproduce. What makes them “retro” is a unique process of genetic information transfer. Instead of transcribing DNA into RNA as all living cells do, they transcribe their RNA into DNA. This viral DNA is then spliced into the host’s genome, where the cell’s synthetic machinery is co-opted to make new virus particles. The 100,000 pieces of retroviral DNA in the human genome are remnants from multiple invasions of our ancestors’ “germline” cells—the cells that allow a host organism to reproduce. Most of these bits of retroviral DNA are degenerated fossils, but some have been exploited during evolution, with profound effects on our physiology. Some present-day circulating retroviruses cause cancers in humans and other animals. Others, like HIV, cause severe immunodeficiencies. But retroviruses also hold clues to innovative approaches that can prevent and treat these diseases. In laboratories around the world, retroviruses continue to shed light on future possibilities that are anything but “retro.”

Discovering Retroviruses

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Author :
Publisher : Harvard University Press
ISBN 13 : 0674971701
Total Pages : 193 pages
Book Rating : 4.6/5 (749 download)

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Book Synopsis Discovering Retroviruses by : Anna Marie Skalka

Download or read book Discovering Retroviruses written by Anna Marie Skalka and published by Harvard University Press. This book was released on 2018-10-15 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately eight percent of our DNA contains retroviral sequences that are millions of years old. Through engaging stories of scientific discovery, Anna Marie Skalka explains our evolving knowledge of these ancient denizens of the biosphere and how this understanding has significantly advanced research in genetic engineering, gene delivery systems, and precision medicine. Discovering Retroviruses begins with the pioneer scientists who first encountered these RNA-containing viruses and solved the mystery of their reproduction. Like other viruses, retroviruses invade the cells of a host organism to reproduce. What makes them “retro” is a unique process of genetic information transfer. Instead of transcribing DNA into RNA as all living cells do, they transcribe their RNA into DNA. This viral DNA is then spliced into the host’s genome, where the cell’s synthetic machinery is co-opted to make new virus particles. The 100,000 pieces of retroviral DNA in the human genome are remnants from multiple invasions of our ancestors’ “germline” cells—the cells that allow a host organism to reproduce. Most of these bits of retroviral DNA are degenerated fossils, but some have been exploited during evolution, with profound effects on our physiology. Some present-day circulating retroviruses cause cancers in humans and other animals. Others, like HIV, cause severe immunodeficiencies. But retroviruses also hold clues to innovative approaches that can prevent and treat these diseases. In laboratories around the world, retroviruses continue to shed light on future possibilities that are anything but “retro.”

Human Retroviruses

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Author :
Publisher : Oxford University Press
ISBN 13 : 9780199633821
Total Pages : 220 pages
Book Rating : 4.6/5 (338 download)

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Book Synopsis Human Retroviruses by : Bryan Cullen

Download or read book Human Retroviruses written by Bryan Cullen and published by Oxford University Press. This book was released on 1993 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.

Retroviral Proteases

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Author :
Publisher : Gulf Professional Publishing
ISBN 13 : 9780121821425
Total Pages : 494 pages
Book Rating : 4.8/5 (214 download)

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Book Synopsis Retroviral Proteases by : Lawrence C. Kuo

Download or read book Retroviral Proteases written by Lawrence C. Kuo and published by Gulf Professional Publishing. This book was released on 1994-09-22 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.

Plague

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1510726357
Total Pages : 604 pages
Book Rating : 4.5/5 (17 download)

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Book Synopsis Plague by : Kent Heckenlively

Download or read book Plague written by Kent Heckenlively and published by Simon and Schuster. This book was released on 2017-02-21 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: On July 22, 2009, a special meeting was held with twenty-four leading scientists at the National Institutes of Health to discuss early findings that a newly discovered retrovirus was linked to chronic fatigue syndrome (CFS), prostate cancer, lymphoma, and eventually neurodevelopmental disorders in children. When Dr. Judy Mikovits finished her presentation the room was silent for a moment, then one of the scientists said, “Oh my God!” The resulting investigation would be like no other in science. For Dr. Mikovits, a twenty-year veteran of the National Cancer Institute, this was the midpoint of a five-year journey that would start with the founding of the Whittemore-Peterson Institute for Neuro-Immune Disease at the University of Nevada, Reno, and end with her as a witness for the federal government against her former employer, Harvey Whittemore, for illegal campaign contributions to Senate Majority Leader Harry Reid. On this journey Dr. Mikovits would face the scientific prejudices against CFS, wander into the minefield that is autism, and through it all struggle to maintain her faith in God and the profession to which she had dedicated her life. This is a story for anybody interested in the peril and promise of science at the very highest levels in our country.

Retroviruses

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Author :
Publisher : Caister Academic Press Limited
ISBN 13 : 9781904455554
Total Pages : 0 pages
Book Rating : 4.4/5 (555 download)

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Book Synopsis Retroviruses by : Reinhard Kurth

Download or read book Retroviruses written by Reinhard Kurth and published by Caister Academic Press Limited. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading scientists in the field review the genomics, molecular biology and pathogenesis of these important viruses, comprehensively covering all the recent advances.

A Planet of Viruses

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022632026X
Total Pages : 133 pages
Book Rating : 4.2/5 (263 download)

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Book Synopsis A Planet of Viruses by : Carl Zimmer

Download or read book A Planet of Viruses written by Carl Zimmer and published by University of Chicago Press. This book was released on 2015-10-06 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: For years, scientists have been warning us that a pandemic was all but inevitable. Now it's here, and the rest of us have a lot to learn. Fortunately, science writer Carl Zimmer is here to guide us. In this compact volume, he tells the story of how the smallest living things known to science can bring an entire planet of people to a halt--and what we can learn from how we've defeated them in the past. Planet of Viruses covers such threats as Ebola, MERS, and chikungunya virus; tells about recent scientific discoveries, such as a hundred-million-year-old virus that infected the common ancestor of armadillos, elephants, and humans; and shares new findings that show why climate change may lead to even deadlier outbreaks. Zimmer’s lucid explanations and fascinating stories demonstrate how deeply humans and viruses are intertwined. Viruses helped give rise to the first life-forms, are responsible for many of our most devastating diseases, and will continue to control our fate for centuries. Thoroughly readable, and, for all its honesty about the threats, as reassuring as it is frightening, A Planet of Viruses is a fascinating tour of a world we all need to better understand.

Necropolis

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Author :
Publisher : Harvard University Press
ISBN 13 : 0674241053
Total Pages : 353 pages
Book Rating : 4.6/5 (742 download)

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Book Synopsis Necropolis by : Kathryn Olivarius

Download or read book Necropolis written by Kathryn Olivarius and published by Harvard University Press. This book was released on 2022-04-19 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction: A rising necropolis -- Patriotic fever -- Danse macabre -- Immunocapital -- Public health, private acclimation -- Denial, delusion, and disunion -- Incumbent arrogance -- Epilogue: Fever and folly.

Retroviruses

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Author :
Publisher : CSHL Press
ISBN 13 : 9780879695712
Total Pages : 856 pages
Book Rating : 4.6/5 (957 download)

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Book Synopsis Retroviruses by : John M. Coffin

Download or read book Retroviruses written by John M. Coffin and published by CSHL Press. This book was released on 1997 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.

Virus

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Author :
Publisher : W. W. Norton
ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Virus by : Luc Montagnier

Download or read book Virus written by Luc Montagnier and published by W. W. Norton. This book was released on 2008 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The co-discoverer of HIV and one of the world's preeminent virologists relates the Pasteur Institute's leading role in investigating the AIDS virus and the virus's devastating course throughout the world. Photos.

Viruses

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Author :
Publisher : Macmillan
ISBN 13 : 0716750317
Total Pages : 261 pages
Book Rating : 4.7/5 (167 download)

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Book Synopsis Viruses by : Arnold Jay Levine

Download or read book Viruses written by Arnold Jay Levine and published by Macmillan. This book was released on 1992 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses the enormous scientific and medical contributions that have come from the field of virology.

Virolution

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Publisher : HarperCollins UK
ISBN 13 : 0007545274
Total Pages : 402 pages
Book Rating : 4.0/5 (75 download)

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Book Synopsis Virolution by : Frank Ryan

Download or read book Virolution written by Frank Ryan and published by HarperCollins UK. This book was released on 2013-11-28 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The extraordinary role of viruses in evolution and how this is revolutionising biology and medicine.

RNA Tumor Viruses: Supplements and appendixes

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Author :
Publisher :
ISBN 13 :
Total Pages : 1254 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis RNA Tumor Viruses: Supplements and appendixes by :

Download or read book RNA Tumor Viruses: Supplements and appendixes written by and published by . This book was released on 1984 with total page 1254 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Viruses

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Author :
Publisher : Harvard University Press
ISBN 13 : 0674972082
Total Pages : 385 pages
Book Rating : 4.6/5 (749 download)

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Book Synopsis Viruses by : Michael G. Cordingley

Download or read book Viruses written by Michael G. Cordingley and published by Harvard University Press. This book was released on 2017-06-19 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: While viruses—the world’s most abundant biological entities—are not technically alive, they invade, replicate, and evolve within living cells. Michael Cordingley goes beyond our familiarity with infections to show how viruses spur evolutionary change in their hosts and shape global ecosystems, from ocean photosynthesis to drug-resistant bacteria.

HIV and the Blood Supply

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Author :
Publisher : National Academies Press
ISBN 13 : 0309053293
Total Pages : 349 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis HIV and the Blood Supply by : Institute of Medicine

Download or read book HIV and the Blood Supply written by Institute of Medicine and published by National Academies Press. This book was released on 1995-10-05 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the early years of the AIDS epidemic, thousands of Americans became infected with HIV through the nation's blood supply. Because little reliable information existed at the time AIDS first began showing up in hemophiliacs and in others who had received transfusions, experts disagreed about whether blood and blood products could transmit the disease. During this period of great uncertainty, decision-making regarding the blood supply became increasingly difficult and fraught with risk. This volume provides a balanced inquiry into the blood safety controversy, which involves private sexual practices, personal tragedy for the victims of HIV/AIDS, and public confidence in America's blood services system. The book focuses on critical decisions as information about the danger to the blood supply emerged. The committee draws conclusions about what was doneâ€"and recommends what should be done to produce better outcomes in the face of future threats to blood safety. The committee frames its analysis around four critical area: Product treatmentâ€"Could effective methods for inactivating HIV in blood have been introduced sooner? Donor screening and referralâ€"including a review of screening to exlude high-risk individuals. Regulations and recall of contaminated bloodâ€"analyzing decisions by federal agencies and the private sector. Risk communicationâ€"examining whether infections could have been averted by better communication of the risks.

Virus Hunting

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Author :
Publisher : Basic Books
ISBN 13 : 9780465098156
Total Pages : 0 pages
Book Rating : 4.0/5 (981 download)

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Book Synopsis Virus Hunting by : Robert C. Gallo

Download or read book Virus Hunting written by Robert C. Gallo and published by Basic Books. This book was released on 1993-08-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The renowned AIDS researcher Robert Gallo tells his story of scientific breakthrough in a riveting portrait of the people, the politics, and the pace of modern scientific discovery.

The Art and Politics of Science

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Author :
Publisher : W. W. Norton & Company
ISBN 13 : 0393073564
Total Pages : 330 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis The Art and Politics of Science by : Harold Varmus

Download or read book The Art and Politics of Science written by Harold Varmus and published by W. W. Norton & Company. This book was released on 2010-05-24 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Nobel Prize–winning cancer biologist, leader of major scientific institutions, and scientific adviser to President Obama reflects on his remarkable career. A PhD candidate in English literature at Harvard University, Harold Varmus discovered he was drawn instead to medicine and eventually found himself at the forefront of cancer research at the University of California, San Francisco. In this “timely memoir of a remarkable career” (American Scientist), Varmus considers a life’s work that thus far includes not only the groundbreaking research that won him a Nobel Prize but also six years as the director of the National Institutes of Health; his current position as the president of the Memorial Sloan-Kettering Cancer Center; and his important, continuing work as scientific adviser to President Obama. From this truly unique perspective, Varmus shares his experiences from the trenches of politicized battlegrounds ranging from budget fights to stem cell research, global health to science publishing.