Differing Routes to Stem Cell Research

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Publisher :
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.:/5 (891 download)

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Book Synopsis Differing Routes to Stem Cell Research by : Renato Giuseppe Mazzolini

Download or read book Differing Routes to Stem Cell Research written by Renato Giuseppe Mazzolini and published by . This book was released on 2012 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells have been in the center of a heated biomedical and biopolitical debate in the first decade of the new millennium. Ethical concerns prevailed. The present volume follows the controversial discussions on stem cells in Italy and Germany, respectively, over the past 15 years. It aims at an assessment of the situation, and its method is comparative. The first part of the book takes a step back and sheds light on the early history of views on stem cells and on cellular reprogramming from the middle of the nineteenth to the end of the twentieth century. Part two and three have a close look on the recent developments in Germany and in Italy from three different viewpoints: the state of the art in scientific research, the public debate on its perceived promises and dangers, and the political and legal regulations that followed. It turns out that, despite their cultural and geographical vicinity, there are significant national differences in the discursive and juridical strategies followed in both European countries.

Differing Routes to Stem Cell Research

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Publisher :
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Differing Routes to Stem Cell Research by : Renato Giuseppe Mazzolini

Download or read book Differing Routes to Stem Cell Research written by Renato Giuseppe Mazzolini and published by . This book was released on 2012 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells have been in the center of a heated biomedical and biopolitical debate in the first decade of the new millennium. Ethical concerns prevailed. The present volume follows the controversial discussions on stem cells in Italy and Germany, respectively, over the past 15 years. It aims at an assessment of the situation, and its method is comparative. The first part of the book takes a step back and sheds light on the early history of views on stem cells and on cellular reprogramming from the middle of the nineteenth to the end of the twentieth century. Part two and three have a close look on the recent developments in Germany and in Italy from three different viewpoints: the state of the art in scientific research, the public debate on its perceived promises and dangers, and the political and legal regulations that followed. It turns out that, despite their cultural and geographical vicinity, there are significant national differences in the discursive and juridical strategies followed in both European countries.

Stem Cells and the Future of Regenerative Medicine

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Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stem Cells and the Future of Regenerative Medicine by : Institute of Medicine

Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Stem Cells: Current Challenges and New Directions

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Publisher : Springer Science & Business Media
ISBN 13 : 1461480663
Total Pages : 379 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Stem Cells: Current Challenges and New Directions by : Kursad Turksen

Download or read book Stem Cells: Current Challenges and New Directions written by Kursad Turksen and published by Springer Science & Business Media. This book was released on 2013-09-24 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume looks at the state-of-the-science in stem cells, discusses the current challenges, and examines the new directions the field is taking. Dr. Turksen, editor-in-chief of the journal "Stem Cell Reviews and Reports," has assembled a volume of internationally-known scientists who cover topics that are both clinically and research-oriented. The contents range from sources of stem cells through their physiological role in health and disease, therapeutic applications in regenerative medicine, and ethics and society. An initial overview and a final summary bookend the contents into a cohesive and invaluable volume.

The Matrix of Stem Cell Research

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Author :
Publisher : Routledge
ISBN 13 : 1351597930
Total Pages : 362 pages
Book Rating : 4.3/5 (515 download)

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Book Synopsis The Matrix of Stem Cell Research by : Christine Hauskeller

Download or read book The Matrix of Stem Cell Research written by Christine Hauskeller and published by Routledge. This book was released on 2019-07-25 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell research has been a problematic endeavour. For the past twenty years it has attracted moral controversies in both the public and the professional sphere. The research involves not only laboratories, clinics and people, but ethics, industries, jurisprudence, and markets. Today it contributes to the development of new therapies and affects increasingly many social arenas. The matrix approach introduced in this book offers a new understanding of this science in its relation to society. The contributions are multidisciplinary and intersectional, illustrating how agency and influence between science and society go both ways. Conceptually, this volume presents a situated and reflexive approach for philosophy and sociology of the life sciences. The practices that are part of stem cell research are dispersed, and the concepts that tie them together are tenuous; there are persistent problems with the validation of findings, and the ontology of the stem cell is elusive. The array of applications shapes a growing bioeconomy that is dependent on patient donations of tissues and embryos, consumers, and industrial support. In this volume it is argued that this research now denotes not a specific field but a flexible web of intersecting practices, discourses, and agencies. To capture significant parts of this complex reality, this book presents recent findings from researchers, who have studied in-depth aspects of this matrix of stem cell research. This volume presents state-of-the-art examinations from senior and junior scholars in disciplines from humanities and laboratory research to various social sciences, highlighting particular normative and epistemological intersections. The book will appeal to scholars as well as wider audiences interested in developments in life science and society interactions. The novel matrix approach and the accessible case studies make this an excellent resource for science and society courses.

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics

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Publisher : Academic Press
ISBN 13 : 0128119217
Total Pages : 548 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics by : Xiao-Dong Chen

Download or read book A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics written by Xiao-Dong Chen and published by Academic Press. This book was released on 2018-08-31 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies

Stem Cells

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Author :
Publisher : CreateSpace
ISBN 13 : 9781492901433
Total Pages : 220 pages
Book Rating : 4.9/5 (14 download)

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Book Synopsis Stem Cells by : Department of Health and Human Services

Download or read book Stem Cells written by Department of Health and Human Services and published by CreateSpace. This book was released on 2013-10-05 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: In February 2001 the Secretary of Health and Human Services requested that the National Institutes of Health prepare a summary report on the state of the science on stem cells. This report was developed in response to his request. It provides the current information about the biology of stem cells derived from all sources—embryo, fetal tissue, and adult. Since 1998, when human pluripotent stem cells were first isolated, research on stem cells has received much public attention, both because of its extraordinary promise and because of relevant legal and ethical issues. Underlying this recent public scrutiny is decades of painstaking work by scientists in many fields, who have been deciphering some of the most fundamental questions about life with the goal of improving health. In the last several decades, investments in basic research have yielded extensive knowledge about the many and complex processes involved in the development of an organism, including the control of cellular development. But many questions remain. How does a single cell—the fertilized egg—give rise to a complex, multi-cellular organism? The question represents a fundamental challenge in developmental biology. Researchers are now seeking to understand in greater detail the genetic factors that regulate cell differentiation in early development. Put simply, stem cells are self-renewing, unspecialized cells that can give rise to multiple types all of specialized cells of the body. The process by which dividing, unspecialized cells are equipped to perform specific functions—muscle contraction or nerve cell communication, for example—is called differentiation, and is fundamental to the development of the mature organism. It is now known that stem cells, in various forms, can be obtained from the embryo, the fetus, and the adult. The report is a review of the state of the science of stem cell research as of June 17, 2001. Included in this report is subject matter addressing stem cells from adult, fetal tissue, and embryonic sources. Because so much of the progress made to date was dependent on animal models, a significant emphasis is placed on understandings gained from mouse models of development and mouse stem cell research. The report also devotes substantial attention to scientific publications on the characterization of specialized cells developed from embryonic stem cells and the plasticity of adult stem cells. Both scientific and lay publications use a variety of terms to describe stem cells and their properties. For this reason, this report adopts a lexicon of terms and it is used consistently throughout. In several places in the report, discovery timelines are provided. The various sources of stem cells are described, as are the techniques used to isolate and develop them. A comprehensive listing of various stem cell isolation and characterizations is also included. In order to ensure the reader is provided information both about the basic biology of stem cells, and their therapeutic potential, the report contains several chapters focused on particular diseases which might benefit from stem cell research. These chapters on the use of hematopoietic stem cells, followed by focus features on specific nervous system diseases, diabetes, heart disease, and autoimmune diseases serve merely as examples of the many applications of stem cells that are being pursued. Also included are features that review aspects of stem cells as therapeutic delivery tools for gene therapy and, importantly, the safety considerations for developing stem cell-based therapies.

Stem Cell Research And Textbook 2

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Author :
Publisher : Nobel TM
ISBN 13 :
Total Pages : 97 pages
Book Rating : 4./5 ( download)

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Book Synopsis Stem Cell Research And Textbook 2 by : Aliasghar Tabatabaei Mohammadi

Download or read book Stem Cell Research And Textbook 2 written by Aliasghar Tabatabaei Mohammadi and published by Nobel TM. This book was released on with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Research And Textbook 2( Dental-derived stem cells, Induced pluripotent stem cells, hematopoietic stem cells, Embryonic, and Cancer Stem cells) For medical students, medical doctors, and researchers.

Stem Cells

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Publisher :
ISBN 13 :
Total Pages : 452 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Stem Cells by :

Download or read book Stem Cells written by and published by . This book was released on 2001 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stem Cells and Tissue Engineering

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Publisher : Springer Science & Business Media
ISBN 13 : 1461455057
Total Pages : 159 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Stem Cells and Tissue Engineering by : Mirjana Pavlovic

Download or read book Stem Cells and Tissue Engineering written by Mirjana Pavlovic and published by Springer Science & Business Media. This book was released on 2012-11-07 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells are the building blocks for all other cells in an organism. The human body has about 200 different types of cells and any of those cells can be produced by a stem cell. This fact emphasizes the significance of stem cells in transplantational medicine, regenerative therapy and bioengineering. Whether embryonic or adult, these cells can be used for the successful treatment of a wide range of diseases that were not treatable before, such as osteogenesis imperfecta in children, different forms of leukemias, acute myocardial infarction, some neural damages and diseases, etc. Bioengineering, e.g. successful manipulation of these cells with multipotential capacity of differentiation toward appropriate patterns and precise quantity, are the prerequisites for successful outcome and treatment. By combining in vivo and in vitro techniques, it is now possible to manage the wide spectrum of tissue damages and organ diseases. Although the stem-cell therapy is not a response to all the questions, it provides more and more answers every day. Stem Cells and Tissue Engineering is a concise review on the functional, phenotypic, regenerative, transplantational and curative aspects of a stem cell’s entity. It is critical and encouraging at the same time, providing truthful and appropriate samples from the practice and research that can lead toward optimal use of this immense source of adjuvant and curative therapy in human pathology. Written by a clinician and a researcher, who are currently teaching what they are doing, it is recommended as a teaching tool along with an original textbook.

Stem Cells: From Bench To Bedside

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Publisher : World Scientific
ISBN 13 : 9814481165
Total Pages : 586 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Stem Cells: From Bench To Bedside by : Ariff Bongso

Download or read book Stem Cells: From Bench To Bedside written by Ariff Bongso and published by World Scientific. This book was released on 2005-07-15 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell biology has gained tremendous interest in the recent years, driven by the hope of finding cures for several diseases through transplantation medicine. Various types of stem cells have been identified from preimplantation embryos, the fetus, placenta and adult. The isolation of human embryonic stem cells has been considered the biggest breakthrough of the 21st century. Some of these stem cell types are charged with ethical controversies although they are versatile and offer tremendous potential for finding cures for incurable diseases. In fact, cures for diabetes, heart diseases, Parkinson's, Alzheimer's, and many other diseases via stem cell research is expected within the next 10 years.The documentation of the latest information on these various stem cell types is compartmentalized in different journals and texts. This book brings together the state-of-the-art on all the types of stem cells, written by giants in the respective fields. It is hoped that knowledge of one stem cell type will complement the other and much can be learned by interaction. This book is aimed at undergraduates, postgraduates, scientists, embryologists, tissue engineers, doctors and biomedical scientists with an interest in stem cell research. It is different from other texts in that it is very comprehensive, covering all aspects of stem cells. Additionally, all the various chapters are written by renowned scientists in the specific fields. The topics are uniquely treated in that they cover research at the laboratory bench as well as the clinical applications. Many of the chapters carry extensive self-explanatory figures, colored photographs, graphics and tables.Both the editors are also renowned in the stem cell field, and both come from medical disciplines and are senior university academics with excellent track records.

Human Embryonic Stem Cells

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Publisher : Springer Science & Business Media
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Human Embryonic Stem Cells by : Arlene Chiu

Download or read book Human Embryonic Stem Cells written by Arlene Chiu and published by Springer Science & Business Media. This book was released on 2003-08 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Stem Cells

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Publisher : John Wiley & Sons
ISBN 13 : 9780470091432
Total Pages : 234 pages
Book Rating : 4.0/5 (914 download)

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Book Synopsis Stem Cells by : Gregory R. Bock

Download or read book Stem Cells written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2005-04-22 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic on the important ethical issues that are raised by research on stem cells. They review the various regulatory regimes, which apply in different countries – a key factor in determining where future stem cell research is carried out. Potential clinical applications covered in the book include the production of cardiomyocytes to replace damaged heart tissue, the production of insulin-producing cells for patients with diabetes, and the generation of neurons for the treatment of patients with Parkinson’s disease or spinal cord injury. Particular attention is paid to the factors that maintain stem cells in a pluripotent state or which drive them to create differentiated and lineage-committed cells in vitro and in vivo. Nuclear reprogramming, the process by which a nucleus acquires developmental potential, is covered here as well. It is relevant to stem cell research generally, and also to research on the cloning of animals by nuclear transfer. This book is an essential purchase for all those engaged in stem cell research, whether in the laboratory, the clinic or the regulatory authorities. From the reviews: "...this book provides: a comprehensive overview of current issues in stem cell research, with contributions from leading figures..." —BRITISH SOCIETY OF CELL BIOLOGY

Stem Cells

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1108663176
Total Pages : 149 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis Stem Cells by : Melinda Bonnie Fagan

Download or read book Stem Cells written by Melinda Bonnie Fagan and published by Cambridge University Press. This book was released on 2021-05-27 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is a stem cell? The answer is seemingly obvious: a cell that is also a stem, or point of origin, for something else. Upon closer examination, however, this combination of ideas leads directly to fundamental questions about biological development. A cell is a basic category of living thing; a fundamental 'unit of life.' A stem is a site of growth; an active source that supports or gives rise to something else. Both concepts are deeply rooted in biological thought, with rich and complex histories. The idea of a stem cell unites them, but the union is neither simple nor straightforward. This book traces the origins of the stem cell concept, its use in stem cell research today, and implications of the idea for stem cell experiments, their concrete results, and hoped-for clinical advances.

Cloning and Stem Cell Research: 3, pts.1 & 2. Legislative developments in cloning research in the United States of America : The President's Council on Bioethics - Cloning

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Publisher :
ISBN 13 : 9789058507518
Total Pages : 0 pages
Book Rating : 4.5/5 (75 download)

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Book Synopsis Cloning and Stem Cell Research: 3, pts.1 & 2. Legislative developments in cloning research in the United States of America : The President's Council on Bioethics - Cloning by : Willem-Jan van der Wolf

Download or read book Cloning and Stem Cell Research: 3, pts.1 & 2. Legislative developments in cloning research in the United States of America : The President's Council on Bioethics - Cloning written by Willem-Jan van der Wolf and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells are cells found in most, if not all, multi-cellular organisms. They are characterized by the ability to renew themselves through cell division and differentiation into a diverse range of specialized cell types. Stem cells can now be grown and transformed into specialized cells with characteristics consistent with cells of various tissues, such as muscles or nerves, through cell culture. For this reason, their use in medical therapies has been proposed. In particular, embryonic cell lines, autologous embryonic stem cells generated through therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates. As promising as this may sound, under the Bush regime, stem cell research in the United States was kept on a very tight leash. Bush limited the various uses of stem cell research enormously through the adaptation of strict legislation. The United States' former president even pronounced that he would use his veto, if the senate would stretch the stem cell legislation beyond his prescribed limits. Now, a whole new era opens for the United States, since Barack Obama already made known he will make important changes to the existing legislation concerning stem cell research. In our viewpoint, this is necessary to put America back on the world map whilst discovering the possibilities of curing diseases with the help of stem cell research. In order to compare the new strategy of Obama to the old path prescribed by Bush regarding stem cell research, insight in existing stem cell legislation is necessary. Therefore, this collection of legislation on stem cell research provides a complete and in-depth overview of the current state of affairs concerning this topic in America. This collection is vital for every legal academic scholar, especially now that the United States are marking the progress of stem cell research as one of their top priorities.

Stem Cells: Promise And Reality

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Author :
Publisher : World Scientific
ISBN 13 : 9813100214
Total Pages : 106 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis Stem Cells: Promise And Reality by : Lygia V Pereira

Download or read book Stem Cells: Promise And Reality written by Lygia V Pereira and published by World Scientific. This book was released on 2016-08-22 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells: Promises and Reality will tell you everything you have always wanted to know about stem cells, but could not understand the field from elsewhere.Stem cells are the great therapeutic promise of the century, and this evolving field of research and medicine brings with it many legal, ethical and psychological issues that must be discussed by society as a whole.Written so as to be accessible to general readers as well as specialists, this book explains what stem cells are, and the different aspects of stem cell research and applications. The book will enable the reader to understand the field sufficiently to critically participate in the public debates regarding stem cell research and society and ethics. By the end of the book, the reader will also be able to judge news on the stem cells field, and to discern what are real advances and what are phony treatments.The main advantage of this book in comparison with other 'stem cells for the general public' books is that it assumes the reader knows NOTHING about biology, except what is already common knowledge (for example, that we are made of cells). The book constructs step by step the required basic biology knowledge in order for the reader to understand all the different aspects of stem cells. At the same time that it is thorough in its stem cells-based content, and will keep the reader engaged with its narrative.

Stem Cells

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Author :
Publisher :
ISBN 13 :
Total Pages : 228 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stem Cells by : National Institutes of Health

Download or read book Stem Cells written by National Institutes of Health and published by . This book was released on 2004-11 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: The makings of future news headlines about tomorrow's life saving therapies starts in the biomedical research laboratory. Ideas abound; early successes and later failures and knowledge gained from both; the rare lightning bolt of an unexpected breakthrough discovery --- this is a glimpse of the behind the scenes action of some of the world's most acclaimed stem cell scientists' quest to solve some of the human body's most challenging mysteries. Stem cells --- what lies ahead? The following chapters explore some of the cutting edge research featuring stem cells. Disease and disorders with no therapies or at best, partially effective ones, are the lure of the pursuit of stem cell research. Described here are examples of significant progress that is a prologue to an era of medical discovery of cell-based therapies that will one day restore function to those whose lives are now challenged every day --- but perhaps in the future, no longer.