Developmental and Fetal Origins of Differences in Monozygotic Twins

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Publisher : Academic Press
ISBN 13 : 0128203072
Total Pages : 386 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Developmental and Fetal Origins of Differences in Monozygotic Twins by : Alexandra Matias

Download or read book Developmental and Fetal Origins of Differences in Monozygotic Twins written by Alexandra Matias and published by Academic Press. This book was released on 2020-05-15 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout. Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical management Discusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysis Features contributions from international experts in twin genetics and developmental biology

3D Physical and Virtual Models in Fetal Medicine

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Publisher : Springer Nature
ISBN 13 : 303114855X
Total Pages : 197 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis 3D Physical and Virtual Models in Fetal Medicine by : Heron Werner

Download or read book 3D Physical and Virtual Models in Fetal Medicine written by Heron Werner and published by Springer Nature. This book was released on 2023-05-26 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological innovations accompanying advances in medicine have given rise to the possibility of obtaining better-defined fetal images that assist in medical diagnosis and contribute toward genetic counseling offered to parents during the prenatal care. 3D printing is an emerging technique with a variety of medical applications such as surgical planning, biomedical research and medical education. Clinical Relevance: 3D physical and virtual models from ultrasound and magnetic resonance imaging have been used for educational, multidisciplinary discussion and plan therapeutic approaches. The authors describe techniques that can be applied at different stages of pregnancy and constitute an innovative contribution to research on fetal abnormalities. We will show that physical models in fetal medicine can help in the tactile and interactive study of complex abnormalities in multiple disciplines. They may also be useful for prospective parents because a 3D physical model with the characteristics of the fetus should allow a more direct emotional connection to their unborn child.

Exploring the Biological Contributions to Human Health

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Publisher : National Academies Press
ISBN 13 : 0309132975
Total Pages : 287 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Exploring the Biological Contributions to Human Health by : Institute of Medicine

Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Twin Research for Everyone

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Publisher : Academic Press
ISBN 13 : 0128215151
Total Pages : 740 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Twin Research for Everyone by : Adam D. Tarnoki

Download or read book Twin Research for Everyone written by Adam D. Tarnoki and published by Academic Press. This book was released on 2022-08-17 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twin Research: Biology, Health, Epigenetics, and Psychology is a comprehensive, applied resource in twinning and twin studies that is grounded in the most impactful findings from twin research in recent years. While targeted to undergraduate and graduate students, this compendium will prove a valuable resource for scholars already familiar with twin studies, as well as those coming to the field for the first time. Here, more than forty experts across an array of disciplines examine twinning and twin research methodologies from the perspectives of biology, medicine, genetic and epigenetic influences, and neuroscience. Chapters provide clear instruction in both basic and advanced research methods, family and parenting aspects of twinning, twin studies as applied across various disease areas and medical specialties, genetic and epigenetic determinants of differentiation, and academic, neurological and cognitive development. The presentation of existing studies and methods instruction empowers students and researchers to apply twin-based research and advance new studies across a range of biomedical and behavioral fields, highlighting current research trends and future directions. Offers unique insights into twinning rates, mechanisms and factors surrounding twinship Provides clear instruction on both basic and advanced twin research methods and study design Features leading international experts in twin biology, genetics, health and psychology Examines findings from recent twin studies across a broad array of health and behavioral studies

Transforming the Workforce for Children Birth Through Age 8

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Publisher : National Academies Press
ISBN 13 : 0309324882
Total Pages : 587 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Transforming the Workforce for Children Birth Through Age 8 by : National Research Council

Download or read book Transforming the Workforce for Children Birth Through Age 8 written by National Research Council and published by National Academies Press. This book was released on 2015-07-23 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and the education of children from birth through age 8 are not acknowledged as a workforce unified by the common knowledge and competencies needed to do their jobs well. Transforming the Workforce for Children Birth Through Age 8 explores the science of child development, particularly looking at implications for the professionals who work with children. This report examines the current capacities and practices of the workforce, the settings in which they work, the policies and infrastructure that set qualifications and provide professional learning, and the government agencies and other funders who support and oversee these systems. This book then makes recommendations to improve the quality of professional practice and the practice environment for care and education professionals. These detailed recommendations create a blueprint for action that builds on a unifying foundation of child development and early learning, shared knowledge and competencies for care and education professionals, and principles for effective professional learning. Young children thrive and learn best when they have secure, positive relationships with adults who are knowledgeable about how to support their development and learning and are responsive to their individual progress. Transforming the Workforce for Children Birth Through Age 8 offers guidance on system changes to improve the quality of professional practice, specific actions to improve professional learning systems and workforce development, and research to continue to build the knowledge base in ways that will directly advance and inform future actions. The recommendations of this book provide an opportunity to improve the quality of the care and the education that children receive, and ultimately improve outcomes for children.

Vibrant and Healthy Kids

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Publisher : National Academies Press
ISBN 13 : 0309493382
Total Pages : 621 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Vibrant and Healthy Kids by : National Academies of Sciences, Engineering, and Medicine

Download or read book Vibrant and Healthy Kids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-12-27 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are the foundation of the United States, and supporting them is a key component of building a successful future. However, millions of children face health inequities that compromise their development, well-being, and long-term outcomes, despite substantial scientific evidence about how those adversities contribute to poor health. Advancements in neurobiological and socio-behavioral science show that critical biological systems develop in the prenatal through early childhood periods, and neurobiological development is extremely responsive to environmental influences during these stages. Consequently, social, economic, cultural, and environmental factors significantly affect a child's health ecosystem and ability to thrive throughout adulthood. Vibrant and Healthy Kids: Aligning Science, Practice, and Policy to Advance Health Equity builds upon and updates research from Communities in Action: Pathways to Health Equity (2017) and From Neurons to Neighborhoods: The Science of Early Childhood Development (2000). This report provides a brief overview of stressors that affect childhood development and health, a framework for applying current brain and development science to the real world, a roadmap for implementing tailored interventions, and recommendations about improving systems to better align with our understanding of the significant impact of health equity.

Perinatology

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Publisher : Springer Nature
ISBN 13 : 3030834344
Total Pages : 1295 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Perinatology by : Renato Augusto Moreira de Sá

Download or read book Perinatology written by Renato Augusto Moreira de Sá and published by Springer Nature. This book was released on 2021-11-18 with total page 1295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest evidence-based guidelines for perinatal management and is designed to help obstetricians and neonatologists minimize complications and offer patients the best possible care. Since 1960, there has been a significant increase in basic and clinical investigations on normal and pathological pregnancy in the developed world. This has provided insights into the physiopathology of pregnant women, fetuses and newborns and led to the development of new technologies, bringing about a new medical subspecialty: perinatal medicine. The book is divided into eight main sections: The first examines basic periconceptional care and discusses the ethical aspects of perinatology. The next section focuses on prenatal considerations, such as the nutritional aspects of gestation and puerperium, physical exercise during pregnancy, routine laboratory tests, prenatal care of multiple gestations and the role of the neonatologist in prenatal care. The third and fourth sections then explore fetal evaluation, and clinical intercurrences in pregnancy, respectively. The next section addresses pregnancy complications: prevention, diagnosis and management. The sixth section covers the basic aspects of congenital infections and the seventh examines labor and delivery aspects. Lastly, the final section includes chapters on neonatal assistance. Written by leading experts in obstetrics, neonatology, and perinatology, this thoroughly updated, comprehensive resource reflects the latest information in all areas, including genetics and imaging.

Placental and Gestational Pathology with Online Resource

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Publisher : Cambridge University Press
ISBN 13 : 1316632539
Total Pages : 367 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Placental and Gestational Pathology with Online Resource by : Raymond W. Redline

Download or read book Placental and Gestational Pathology with Online Resource written by Raymond W. Redline and published by Cambridge University Press. This book was released on 2018-08-23 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to identifying disease processes in the placenta affecting pregnancy outcome, with current diagnostic criteria and clinical consequences.

Personalized Epigenetics

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Publisher : Elsevier
ISBN 13 : 0443238030
Total Pages : 782 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Personalized Epigenetics by : Trygve Tollefsbol

Download or read book Personalized Epigenetics written by Trygve Tollefsbol and published by Elsevier. This book was released on 2024-08-01 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Epigenetics, Second Edition discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. Fully updated and revised, this new edition details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field. It also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics. Most importantly, the text covers personalized epigenetics from a disease-oriented perspective, presenting chapters that provide advances in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management. Includes new chapters on topics such as the limitations of personalized epigenetic variation comparisons; personalized epigenetics technologies; epigenetics of personalized nanomedicine; personalized epigenetic management of diabetes; epigenetics and chemoresistance; and personalized epigenetics and neurological disorders Covers key methodological processes that are important in personalized medicine Offers disease research case studies to provide in-depth discussion of examples of recent epigenetic research on a disease area Features topics such as forensic epigenetics, epigenetics of personalized toxicity, limitations of epigenetic variation comparisons, and nanomedicine and nutrigenomics as applied to personalized epigenetics

Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia

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Publisher : Frontiers Media SA
ISBN 13 : 2889669041
Total Pages : 141 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia by : Henry Houlden

Download or read book Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia written by Henry Houlden and published by Frontiers Media SA. This book was released on 2021-06-28 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Old and New Perspectives on Mortality Forecasting

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Publisher : Springer
ISBN 13 : 3030050750
Total Pages : 349 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Old and New Perspectives on Mortality Forecasting by : Tommy Bengtsson

Download or read book Old and New Perspectives on Mortality Forecasting written by Tommy Bengtsson and published by Springer. This book was released on 2019-03-28 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes methods of mortality forecasting and discusses possible improvements. It contains a selection of previously unpublished and published papers, which together provide a state-of-the-art overview of statistical approaches as well as behavioural and biological perspectives. The different parts of the book provide discussions of current practice, probabilistic forecasting, the linearity in the increase of life expectancy, causes of death, and the role of cohort factors. The key question in the book is whether it is possible to project future mortality accurately, and if so, what is the best approach. This makes the book a valuable read to demographers, pension planners, actuaries, and all those interested and/or working in modelling and forecasting mortality.

Placental-Fetal Growth Restriction

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Publisher : Cambridge University Press
ISBN 13 : 1108548180
Total Pages : 300 pages
Book Rating : 4.1/5 (85 download)

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Book Synopsis Placental-Fetal Growth Restriction by : Christoph Lees

Download or read book Placental-Fetal Growth Restriction written by Christoph Lees and published by Cambridge University Press. This book was released on 2018-03-31 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master the effective evaluation, analysis and management of placental-fetal growth restriction (PFGR), reducing the risk of perinatal mortality and morbidity in patients worldwide. Extensively researched by international experts, this manual provides practitioners with a detailed, hands-on approach to the practical 'pearls' for direct patient management. This authoritative volume advises on matters such as the correct evaluation and management of high-risk patients in danger of PFGR through to delivery. Extensive and wide-ranging, this book is an invaluable companion to the developing research interest and clinical applications in PFGR, including developmental outcomes in early childhood. Featuring a critical evaluation of a variety of abnormal conditions, such as fetal hypoxia, which are clearly displayed through extensive illustrations. This essential toolkit ensures that practitioners of all levels can effectively limit the risk of mortality and morbidity, and reach the correct diagnosis, first-time.

Culture Media, Solutions, and Systems in Human ART

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Publisher : Cambridge University Press
ISBN 13 : 1139917358
Total Pages : 307 pages
Book Rating : 4.1/5 (399 download)

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Book Synopsis Culture Media, Solutions, and Systems in Human ART by : Patrick Quinn

Download or read book Culture Media, Solutions, and Systems in Human ART written by Patrick Quinn and published by Cambridge University Press. This book was released on 2014-03-27 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes culture media and solutions used in human ART; how they have been developed for in vitro human pre-implantation embryo development, the function and importance of the various components in media and solutions and how they interact, and how the systems in which these are used can influence outcomes. Chapters discuss inorganic solutes, energy substrates, amino acids, macromolecules, cytokines, growth factors, buffers, pH, osmolality, and the interaction of these parameters. The role of incubators and other physical factors are reviewed, along with the relevance and prospects of emerging technologies: morphokinetic analysis using time-lapse imaging and dynamic fluid incubation systems. Results of prospective randomized trials are emphasized to ascertain the added value of these techniques for selecting viable embryos. This comprehensive guide will be invaluable for embryologists, physicians and all personnel involved in the fluid products used in human ART seeking to optimize their successful use of these components.

Someone Else's Twin

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Publisher : Prometheus Books
ISBN 13 : 1616144386
Total Pages : 297 pages
Book Rating : 4.6/5 (161 download)

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Book Synopsis Someone Else's Twin by : Nancy L. Segal

Download or read book Someone Else's Twin written by Nancy L. Segal and published by Prometheus Books. This book was released on 2011-07-19 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: The combination of a riveting true story and cutting-edge twin research makes this book an irresistible page-turner. Identical twins Begoña and Delia were born thirty-eight years ago in Spain’s Canary Islands. Due to chaotic conditions at the hospital or simple human error, the unthinkable happened: Delia was unintentionally switched with another infant in the baby nursery. This fascinating story describes in vivid detail the consequences of this unintentional separation of identical twin sisters. The author considers not only the effects on these particular sisters, but the important implications of this and similar cases for questions concerning identity, familial bonds, nature-nurture, and the law.

Scientific and Medical Aspects of Human Reproductive Cloning

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Publisher : National Academies Press
ISBN 13 : 0309076374
Total Pages : 295 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Scientific and Medical Aspects of Human Reproductive Cloning by : National Research Council

Download or read book Scientific and Medical Aspects of Human Reproductive Cloning written by National Research Council and published by National Academies Press. This book was released on 2002-06-17 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.

Twin Mythconceptions

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Publisher : Academic Press
ISBN 13 : 0128039957
Total Pages : 336 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Twin Mythconceptions by : Nancy L. Segal

Download or read book Twin Mythconceptions written by Nancy L. Segal and published by Academic Press. This book was released on 2017-02-08 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twin Mythconceptions: False Beliefs, Fables, and Facts about Twins sheds new light on over 70 commonly held ideas and beliefs about the origins and development of identical and fraternal twins. Using the latest scientific findings from psychology, psychiatry, biology, and education, the book separates fact from fiction. Each idea about twins is described, followed by both a short answer about the truth, and then a longer, more detailed explanation. Coverage includes embryology of twins, twin types, intellectual growth, personality traits, sexual orientation of twins, marital relationships, epigenetic analyses, and more. Five appendices cover selected topics in greater depth, such as the frequency of different twin types and the varieties of polar body twin pairs. This book will inform and entertain behavioral and life science researchers, health professionals, twins, parents of twins, and anyone interested in the fascinating topic of twins. Identifies common misunderstandings about twins Provides scientific answers to questions about twins Encompasses the biology, psychology, genetics, and personality of twins Includes discussion of identical, fraternal same-sex, and fraternal opposite-sex twins Allows for quick answers to common questions and more detailed explanations

Noninvasive Prenatal Testing (NIPT)

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Publisher : Academic Press
ISBN 13 : 0128141905
Total Pages : 408 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Noninvasive Prenatal Testing (NIPT) by : Lieve Page-Christiaens

Download or read book Noninvasive Prenatal Testing (NIPT) written by Lieve Page-Christiaens and published by Academic Press. This book was released on 2018-08-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its introduction in 2012, cell-free (cf) DNA based Non-Invasive Prenatal Testing (NIPT) has been employed to test for fetal chromosome abnormalities, and gene mutations that lead to a variety of genetic conditions, by millions of pregnant women, in more than 90 countries worldwide. With Noninvasive Prenatal Testing (NIPT): Applied Genomics in Prenatal Screening and Diagnosis, Dr Lieve Page-Christiaens and Dr Hanns-Georg Klein have compiled the first authoritative volume on cfDNA NIPT methods and their clinical implementation. Provides a thorough, practical examination of the history of NIPT, NIPT laboratory techniques and bioinformatics, NIPT screening and diagnostics for a wide range of disorders and birth defects Presents leading, international experts who discuss the application of NIPT in early screening for common aneuploidies, fetal chromosome anomalies, autosomal trisomies, fetal blood group typing, and maternal constitutional and acquired copy number variants Includes full color imagery that enhances concept illustration, along with detailed descriptions of the benefits (and limitations) of NIPT Offers clinicians, researchers, genetic counselors and reproductive specialists of all kinds the required background information, methodologies and essential patient counseling techniques