Polymeric nanoparticles for the treatment of solid tumors

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Author :
Publisher : Springer Nature
ISBN 13 : 3031148487
Total Pages : 515 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Polymeric nanoparticles for the treatment of solid tumors by : Santwana Padhi

Download or read book Polymeric nanoparticles for the treatment of solid tumors written by Santwana Padhi and published by Springer Nature. This book was released on 2022-11-14 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the emerging research in the field of treatment of solid tumors or cancer with new drug delivery systems using nanotechnology. Nanotechnology has given us a good scope for development of new innovative drug delivery strategies to increase the therapeutic efficacy of anticancer drugs with reduced off-target side effects. Cancer is one of the main causes of death worldwide due to the limitations of classical therapies such as low solubility of active drugs, toxic side effects on healthy cells and resistance of tumor cells. These issues are partly solved by the recent development of polymeric nanoparticles, which improve drug absorption and the therapeutic index, while reducing side effects. Drug carriers must be biocompatible, biodegradable and non-immunogenic. Coupled to a ligand that has affinity for that particular cell, polymeric nanoparticles are used to target specifically malignant cells or tissues and, in turn, improve drug stability. This book presents the latest advances in the application of polymeric particles for cancer treatment, with focus on the tumor microenvironment, synthesis, active and passive targeting, patents, targeting over-expressed receptors, tumor-targeting ligands, theranostics, glioblastoma tumors, lung cancer, breast cancer, prostate cancer and pH-responsive nanoparticles

Biomedical Polymers

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Author :
Publisher : CRC Press
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Biomedical Polymers by : Mike Jenkins

Download or read book Biomedical Polymers written by Mike Jenkins and published by CRC Press. This book was released on 2007-09-10 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of the latest research on biomedical polymers, this book discusses natural, synthetic, biodegradable and non bio-degradable polymers and their applications. Chapters discuss polymeric scaffolds for tissue engineering and drug delivery systems, the use of polymers in cell encapsulation, their role as replacement materials for heart valves and arteries, and their applications in joint replacement. The book also discusses the use of polymers in biosensor applications. Edited by an expert team of reasearchers and containing contributions from pioneers throughout the field, the book is an essential reference for scientists and all those developing and using this important group of biomaterials.

Biodegradable Polymers in Clinical Use and Clinical Development

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Publisher : John Wiley & Sons
ISBN 13 : 1118015800
Total Pages : 594 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Biodegradable Polymers in Clinical Use and Clinical Development by : Abraham J. Domb

Download or read book Biodegradable Polymers in Clinical Use and Clinical Development written by Abraham J. Domb and published by John Wiley & Sons. This book was released on 2011-05-12 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.

Handbook of Polymer and Ceramic Nanotechnology

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Publisher : Springer
ISBN 13 : 9783030405120
Total Pages : 1667 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Handbook of Polymer and Ceramic Nanotechnology by : Chaudhery Mustansar Hussain

Download or read book Handbook of Polymer and Ceramic Nanotechnology written by Chaudhery Mustansar Hussain and published by Springer. This book was released on 2021-09-13 with total page 1667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook examines the recent advances in the nanotechnology of polymers and ceramics, which possess outstanding mechanical properties and compatibility given their unique physical and chemical properties caused by the unusually large surface area to volume ratios and high interfacial reactivity. This handbook highlights the various compositions and morphologies of polymer and ceramic nanomaterials that can serve as powerful tools for the diverse applications in areas such as electronics, photonics, shape-memory alloys, biomaterials and biomedical nanomaterials, graphene-based technologies, and textiles and packaging. The handbook addresses safety, economics, green production and sustainability. The book contains a section on functionalization of these molecules, which only increases the possibility of developing even more versatile materials that can be fine-tuned for specific applications. Filling a gap in the literature, this handbook provides comprehensive coverage of properties, fabrication, characterization, functionalization methods and applications at both experimental and theoretical models scales. Economic, toxicological, regulatory, and environmental concerns regarding applications are also discussed in detail. Special attention is paid to sustainable approaches that reduce costs in terms of chemicals and time consumption. The book covers research trends, challenges, and prospective topics as well.

A Handbook of Applied Biopolymer Technology

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1849733457
Total Pages : 501 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis A Handbook of Applied Biopolymer Technology by : Sanjay K Sharma

Download or read book A Handbook of Applied Biopolymer Technology written by Sanjay K Sharma and published by Royal Society of Chemistry. This book was released on 2011-06-20 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists are conducting active research in different fields of engineering, science and technology by adopting the Green Chemistry Principles and methodologies to devise new processes, with a view to help protect and ultimately save the environment from further anthropogenic interruptions and damage. With this in mind, the book provides an up-to-date, coherently written and objectively presented set of chapters from eminent international researchers who are actively involved in academic and technological research in the synthesis, (bio)degradation, testing and applications of biodegradable polymers and biopolymers. This pool of the latest ideas, recent research and technological progress, together with a high level of thinking with a comprehensive perspective, makes the emerging field of biodegradable polymer science and engineering (or bio-based polymers) linked to environmental sustainability, the essence of this key publication. The handbook consists of chapters written and contributed by international experts from academia who are world leaders in research and technology in sustainability and biopolymer and biodegradable polymer synthesis, characterisation, testing and use. The book highlights the following areas: green polymers; biopolymers and bionanocomposites; biodegradable and injectable polymers; biodegradable polyesters; synthesis and physical properties; discovery and characterization of biopolymers; degradable bioelastomers, lactic acid based biodegradable polymers; enzymatic degradation of biodegradable polymers; biodegradation of polymers in the composting environment; recent development in biodegradable polymers; research and applications and biodegradable foams. The book is aimed at technical, research-orientated and marketing people in industry, universities and institutions. It will also be of value to the worldwide public interested in sustainability issues and biopolymer development as well as others interested in the practical means that are being used to reduce the environmental impacts of chemical processes and products, to further eco-efficiency, and to advance the utilization of renewable resources for a bio-based production and supplier chain. Readers will gain a comprehensive and consolidated overview of the immense potential and ongoing research in bio-based and biodegradable polymer science, engineering and technology to make the world greener.

Emerging Roles of Nanocarrier in Cancer Therapy

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Author :
Publisher : CRC Press
ISBN 13 : 1040105998
Total Pages : 273 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Emerging Roles of Nanocarrier in Cancer Therapy by : Rishabha Malviya

Download or read book Emerging Roles of Nanocarrier in Cancer Therapy written by Rishabha Malviya and published by CRC Press. This book was released on 2024-09-05 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the limitations of existing therapeutic approaches using nanoparticles. Emerging Roles of Nanocarriers in Cancer Therapy will further provide information for the development of successful cancer nanomedicine therapies. Features Explains different types of nanoparticles, targeting mechanisms, and approved nanotherapeutics for oncological implications in cancer treatment. Covers in detail the characteristics of various nanotechnology-based drug delivery systems. Discusses passive and active cellular targeting, ligand-based targeting of nanoparticles, and strategies to improve nanoparticle-cellular membrane interaction. Presents the application of nanotherapeutics, current challenges, and prospects, and describes the path of future research. Highlights smart strategies for improving the clinical impact of cancer nanomedicine. The text is primarily written for graduate students, and academic researchers in the fields of biotechnology, nanotechnology, drug delivery, pharmaceutical science, and pharmacology.

Biopolymers

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Author :
Publisher : Elsevier
ISBN 13 : 032390940X
Total Pages : 479 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Biopolymers by : Valentina Sessini

Download or read book Biopolymers written by Valentina Sessini and published by Elsevier. This book was released on 2023-04-21 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopolymers: Synthesis, Properties, and Emerging Applications presents the state-of-the-art in biopolymers, bringing together detailed information on synthesis strategies, processing and cutting-edge applications. The book begins by introducing the synthesis, processing and structural and functional properties of smart biopolymers and bionanocomposites. Subsequent chapters focus on the synthesis and preparation of biopolymers with valuable properties or for specific advanced applications, including piezoelectric properties, shape memory properties, biodegradable polymer blends, synthesis and assembly of nanomaterials, synthesis of green biopolymers, and catalytic synthesis of bio-sourced polyesters and polycarbonate, as well as applications in active food packaging, water purification, biomedicine, 3D printing, and automotive. Throughout the book, there are analyses of different synthesis strategies and processing methods and their role and use in different fields of application, whilst the important challenges relating to scalable processing and shaping and micro and nano structuration are also discussed. The book also strives to balance the synthetic aspects of biopolymers with physical principles, highlighting biopolymer-based architectures including composite or hybrid conjugates, providing in-depth discussion of important examples of reaction mechanisms, and exploring potential applications of biopolymer and conjugates, ranging from physical to chemical and biological systems. - Provides the reader with a broad and detailed overview of the latest advances in biopolymers, covering synthesis, processing, properties and applications - Examines synthesis strategies and processing methods, focusing on green and sustainable catalytic synthesis approaches for biopolymer production - Reviews smart applications of biopolymers, including active food packaging, photocatalytic, electric, electronic, piezoelectric, antimicrobial, environmental, and more

The Lancet

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Publisher :
ISBN 13 :
Total Pages : 768 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis The Lancet by :

Download or read book The Lancet written by and published by . This book was released on 1995-03 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biodegradation

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 953511154X
Total Pages : 382 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Biodegradation by : Rolando Chamy

Download or read book Biodegradation written by Rolando Chamy and published by BoD – Books on Demand. This book was released on 2013-06-14 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a collection of different biodegradation research activities where biological processes take place. The book has two main sections: A) Polymers and Surfactants Biodegradation and B) Biodegradation: Microbial Behaviour.

Advances in Daunorubicin Research and Application: 2011 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464933731
Total Pages : 78 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Advances in Daunorubicin Research and Application: 2011 Edition by :

Download or read book Advances in Daunorubicin Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Daunorubicin Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Daunorubicin in a concise format. The editors have built Advances in Daunorubicin Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Daunorubicin in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Daunorubicin Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

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Author :
Publisher : Academic Press
ISBN 13 : 0128173319
Total Pages : 434 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics by : Prashant Kesharwani

Download or read book Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics written by Prashant Kesharwani and published by Academic Press. This book was released on 2019-06-25 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. - Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy - Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer - Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles

New Approaches to the Management of Primary and Secondary CNS Tumors

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 953513051X
Total Pages : 216 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis New Approaches to the Management of Primary and Secondary CNS Tumors by : Lee Roy Morgan

Download or read book New Approaches to the Management of Primary and Secondary CNS Tumors written by Lee Roy Morgan and published by BoD – Books on Demand. This book was released on 2017-03-23 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several new concepts are reviewed and discussed in this book and allude to the transport of drugs bound to red blood cells into the vascular blood-brain barrier and into cancer cells. Such a transport system is novel and of potential therapeutic potential. It is the goal of this book to provide information and data that will be useful for others to develop new approaches for the management of CNS malignancies.

Polymeric Biomaterials

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Publisher : CRC Press
ISBN 13 : 1420094696
Total Pages : 840 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Polymeric Biomaterials by : Severian Dumitriu

Download or read book Polymeric Biomaterials written by Severian Dumitriu and published by CRC Press. This book was released on 2013-01-17 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials have had a major impact on the practice of contemporary medicine and patient care. Growing into a major interdisciplinary effort involving chemists, biologists, engineers, and physicians, biomaterials development has enabled the creation of high-quality devices, implants, and drug carriers with greater biocompatibility and biofunctiona

Design and Development of New Nanocarriers

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Author :
Publisher : William Andrew
ISBN 13 : 0128136286
Total Pages : 769 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Design and Development of New Nanocarriers by : Alexandru Mihai Grumezescu

Download or read book Design and Development of New Nanocarriers written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2017-11-30 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design and Development of New Nanocarriers focuses on the design and development of new nanocarriers used in pharmaceutical applications that have emerged in recent years. In particular, the pharmaceutical uses of microfluidic techniques, supramolecular design of nanocapsules, smart hydrogels, polymeric micelles, exosomes and metal nanoparticles are discussed in detail. Written by a diverse group of international researchers, this book is a valuable reference resource for those working in both biomaterials science and the pharmaceutical industry. - Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products - Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years - Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry

Micro- and Nanotechnologies-Based Product Development

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Author :
Publisher : CRC Press
ISBN 13 : 1000421600
Total Pages : 327 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Micro- and Nanotechnologies-Based Product Development by : Neelesh Kumar Mehra

Download or read book Micro- and Nanotechnologies-Based Product Development written by Neelesh Kumar Mehra and published by CRC Press. This book was released on 2021-09-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive information of the nanotechnology-based pharmaceutical product development including a diverse range of arenas such as liposomes, nanoparticles, fullerenes, hydrogels, thermally responsive externally activated theranostics (TREAT), hydrogels, microspheres, micro- and nanoemulsions and carbon nanomaterials. It covers the micro- and nanotechnological aspects for pharmaceutical product development with the product development point of view and also covers the industrial aspects, novel technologies, stability studies, validation, safety and toxicity profiles, regulatory perspectives, scale-up technologies and fundamental concept in the development of products. Salient Features: Covers micro- and nanotechnology approaches with current trends with safety and efficacy in product development. Presents an overview of the recent progress of stability testing, reverse engineering, validation and regulatory perspectives as per regulatory requirements. Provides a comprehensive overview of the latest research related to micro- and nanotechnologies including designing, optimisation, validation and scale-up of micro- and nanotechnologies. Is edited by two well-known researchers by contribution of vivid chapters from renowned scientists across the globe in the field of pharmaceutical sciences. Dr. Neelesh Kumar Mehra is working as an Assistant Professor of Pharmaceutics & Biopharmaceutics at the Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He received ‘TEAM AWARD’ for successful commercialisation of an ophthalmic suspension product. He has authored more than 60 peer-reviewed publications in highly reputed international journals and more than 10 book chapter contributions. He has filed patents on manufacturing process and composition to improved therapeutic efficacy for topical delivery. He guided PhD and MS students for their dissertations/research projects. He has received numerous outstanding awards including Young Scientist Award and Team Award for his research output. He recently published one edited book, ‘Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives’, in CRC Press. Currently, he is editing books on nano drug delivery-based products with Elsevier Pvt Ltd. He has rich research and teaching experience in the formulation and development of complex, innovative ophthalmic and injectable biopharmaceutical products including micro- and nanotechnologies for regulated market. Dr. Arvind Gulbake is working as an Assistant Professor at the Faculty of Pharmacy, School of Pharmaceutical & Population Health Informatics, at DIT University, Dehradun, India. He has authored more than 40 peer-reviewed publications in highly reputed international journals, four book chapters and a patent contribution. He has received outstanding awards including Young Scientist Award and BRG Travel Award for his research. He is an assistant editor for IJAP. He guided PhD and MS students for their dissertations/research projects. He has successfully completed extramural project funded by SERB, New Delhi, Government of India. He has more than 12 years of research and teaching experience in the formulation and development of nanopharmaceuticals.

Brain Targeted Drug Delivery Systems

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Publisher : Academic Press
ISBN 13 : 012814002X
Total Pages : 502 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Brain Targeted Drug Delivery Systems by : Huile Gao

Download or read book Brain Targeted Drug Delivery Systems written by Huile Gao and published by Academic Press. This book was released on 2018-09-20 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. - Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers - Discusses key points in developing brain targeting drug delivery systems - Summarizes and presents currently available strategies for brain targeting drug delivery - Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research

Drug Delivery in Oncology

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Publisher : John Wiley & Sons
ISBN 13 : 3527647759
Total Pages : 1828 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Drug Delivery in Oncology by : Felix Kratz

Download or read book Drug Delivery in Oncology written by Felix Kratz and published by John Wiley & Sons. This book was released on 2013-09-30 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.