Development Of An Oral Drug Delivery Platform Formulation For The Targeted Delivery Of Celecoxib For The Chemoprevention And Treatment Of Colorectal Cancer

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Development of an Oral Drug Delivery Platform Formulation for the Targeted Delivery of Celecoxib for the Chemoprevention and Treatment of Colorectal Cancer

Author : Bernard McDonald
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)

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Book Synopsis Development of an Oral Drug Delivery Platform Formulation for the Targeted Delivery of Celecoxib for the Chemoprevention and Treatment of Colorectal Cancer by : Bernard McDonald

Download or read book Development of an Oral Drug Delivery Platform Formulation for the Targeted Delivery of Celecoxib for the Chemoprevention and Treatment of Colorectal Cancer written by Bernard McDonald and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The anti-inflammatory drug celecoxib (CLX) has been shown to exert protective effects in colorectal cancer (CRC) therapy. The primary objective of this study was to develop and characterize a novel CLX multiparticulate drug delivery technology suitable for use in the treatment and prevention of CRC which has the potential to minimize the side effects associated with CLX. Liquid CLX formulations were developed as precursors to CLX microbeads and the effect of formulated CLX samples on the viability and motility of a CRC cell line was examined. CLX liquid formulations were shown for the first time to have an enhanced effect in comparison to the marketed CLX product Celebrex®. Liquid CLX formulations were translated into an optimized CLX microbead formulation which met a number of pre-defined critical quality attributes. A sustained release coat was applied to the beads. An in-vivo study was performed to compare the effect of the coated CLX microbeads versus Celebrex® in the attenuation of CRC tumours and inflammation in a CRC mouse model. Whilst the level of CRC tumour attenuation and inflammation was comparable between both formulations, the CLX microbead statistically outperformed Celebrex®. Microbead production was scaled-up and subsequent coating optimisation studies were performed resulting in products that met pre-defined target product profiles for both murine and human colon delivery. Finally a screening study to assess the applicability of the platform formulation to a range of APIs other than CLX was performed with 50% of the actives screened being successfully incorporated into microbeads. In summary, the in-vitro and in-vivo results described in this thesis present a significant step forward in CRC therapy using CLX, as the microbead formulation developed poses the possibility of presenting CLX in a format that has the potential to minimize GI and CV side effects whilst enhancing the effectiveness of the treatment.

Surgical Techniques in Rectal Cancer

Author : Giovanni Dapri
Publisher : Springer
ISBN 13 : 443155579X
Total Pages : 597 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Surgical Techniques in Rectal Cancer by : Giovanni Dapri

Download or read book Surgical Techniques in Rectal Cancer written by Giovanni Dapri and published by Springer. This book was released on 2018-02-09 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the various procedures, including surgery through the abdominal wall, through a transanal access or by the union of both, using an open, laparoscopic, or robotic approach. Worldwide pioneers for each technique are invited as authors and portray in step-by-step detail about each procedure. Of the 32 chapters, 23 are dedicated only for the surgical procedures. Each chapter is enriched by numerous figures, which complement the text, permitting the understanding of each surgical technique from its beginning until the last step. Eight additional chapters are dedicated to the clinical and anatomical aspects of rectal cancer. In the last decade there has been an impressive evolution in the treatment of patients with rectal cancer, with a focus not only on the preservation of a cancer-free life, but the quality of that life. This book has been written to be useful for everyone involved in rectal cancer management. From internists, gastroenterologists, endoscopists, oncologists, radiotherapists and radiologists involved in the treatment of rectal cancer during their daily practice, to surgeons specialized in colorectal surgery, to junior faculty to trainees, all interested in new and innovative techniques.

Dendrimers for Drug Delivery

Author : Anil K. Sharma
Publisher : CRC Press
ISBN 13 : 135136068X
Total Pages : 406 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Dendrimers for Drug Delivery by : Anil K. Sharma

Download or read book Dendrimers for Drug Delivery written by Anil K. Sharma and published by CRC Press. This book was released on 2018-07-27 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.

Anticancer Agents from Natural Products

Author : Gordon M. Cragg
Publisher : CRC Press
ISBN 13 : 1420039652
Total Pages : 610 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Anticancer Agents from Natural Products by : Gordon M. Cragg

Download or read book Anticancer Agents from Natural Products written by Gordon M. Cragg and published by CRC Press. This book was released on 2005-06-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen

Controlled Pulmonary Drug Delivery

Author : Hugh D.C. Smyth
Publisher : Springer Science & Business Media
ISBN 13 : 1441997458
Total Pages : 560 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Controlled Pulmonary Drug Delivery by : Hugh D.C. Smyth

Download or read book Controlled Pulmonary Drug Delivery written by Hugh D.C. Smyth and published by Springer Science & Business Media. This book was released on 2011-06-24 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

Author : Bharat B. Aggarwal
Publisher : Springer Science & Business Media
ISBN 13 : 0387464018
Total Pages : 502 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease by : Bharat B. Aggarwal

Download or read book The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease written by Bharat B. Aggarwal and published by Springer Science & Business Media. This book was released on 2007-08-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Uterine Fibroids

Author : Nash S. Moawad
Publisher : Springer
ISBN 13 : 3319587803
Total Pages : 386 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Uterine Fibroids by : Nash S. Moawad

Download or read book Uterine Fibroids written by Nash S. Moawad and published by Springer. This book was released on 2017-10-13 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprised of clinical cases presenting diverse clinical scenarios of uterine fibroids, this concise, practical casebook will provide clinicians in reproductive medicine and obstetrics/gynecology with the best real-world strategies to properly diagnose and treat the various presentations of fibroids they may encounter in daily clinical practice. Opening with chapters discussing classification and pathogenesis, effects on fertility and treatment modalities for these common tumors, each subsequent chapter is a case that provides a unique clinical presentation of a patient’s symptoms and clinical findings, diagnostic work-up and the thought process involved in navigating the treatment options as well as the supporting evidence. Cases included illustrate different types and locations of fibroids in addition to various management strategies, complications and outcomes, and selected chapters also include video clips. Pragmatic and reader-friendly, Uterine Fibroids: A Clinical Casebook is written by experts in the field and is designed to facilitate and guide reproductive medicine specialists and gynecologists in the sometimes challenging decision-making process by presenting real case scenarios that span the spectrum of fibroid presentations and treatment options.

Drug Repurposing in Cancer Therapy

Author : Kenneth K.W. To
Publisher : Academic Press
ISBN 13 : 0128199032
Total Pages : 460 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug Repurposing in Cancer Therapy by : Kenneth K.W. To

Download or read book Drug Repurposing in Cancer Therapy written by Kenneth K.W. To and published by Academic Press. This book was released on 2020-07-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. - Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research - Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences - Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Author : William Figg
Publisher : Humana Press
ISBN 13 : 9781588291776
Total Pages : 623 pages
Book Rating : 4.2/5 (917 download)

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Book Synopsis Handbook of Anticancer Pharmacokinetics and Pharmacodynamics by : William Figg

Download or read book Handbook of Anticancer Pharmacokinetics and Pharmacodynamics written by William Figg and published by Humana Press. This book was released on 2004-03-26 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.

Cinnamon

Author : Ranjith Senaratne
Publisher : Springer Nature
ISBN 13 : 3030544265
Total Pages : 453 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Cinnamon by : Ranjith Senaratne

Download or read book Cinnamon written by Ranjith Senaratne and published by Springer Nature. This book was released on 2021-01-25 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cinnamon is the common name for the spice obtained from the dried inner bark of several species of the genus Cinnamomum in the Lauraceae family. In world trade, Cinnamomum cassia (L.) J. Presl Cinnamomum burmannii dominate, but it is of a different quality to ‘true’ or ‘Ceylon’ cinnamon produced from Cinnamomum zeylanicum Blume (C. verum J. Presl), with the latter much easier to process, giving a more delicate, sweeter flavor with nuances of clove, but more importantly with only traces (often below detection thresholds) of coumarin, compared with 5–7 g/kg in other species. Cinnamon has been a popular and expensive spice in many civilizations, including ancient Egypt, Rome and in 14th and 15th century Europe, where it was used primarily to preserve meat for its antibacterial properties, fine aroma and flavor. Ancient Egyptians used cinnamon in mummification process due to its antibacterial properties and fragrance. The quest for cinnamon brought many explorers to Ceylon, whose ancient history is intertwined with the cinnamon trade. Ancient Egyptians and Romans used cinnamon as a valued spice and as an incense. In recent years, much research has been conducted in crop improvement, processing and value addition in cinnamon. In addition to direct use as a condiment/spice, cinnamon has found a multitude of uses in the food and beverage, traditional medicine, pharmacology, nutraceutical and cosmetics industries. Ceylon cinnamon is unique in that oils distilled from the bark (major constituents are cinnamaldehyde and oleoresins), leaf (eugenol is the major constituent used in dentistry, perfumes, flavorings and as an antioxidant) and roots (camphor) have different industrial uses. Cinnamaldehyde is now a proven natural bactericide widely used in food and beverage industry, effective against Salmonella spp. and Escherichia coli. Thus, it has become an important natural component of organic fruit and vegetable juices to enhance microbial safety of these nutritious beverages. Because of its manifold uses, cinnamon is an important crop. There have been many recent publications on its ethnobotany, genetics, crop improvement, agronomy, processing, biotechnology, chemistry, food and medicinal uses, and industrial applications. However, one book condensing all these findings is lacking. Our publication, with chapters devoted to all these aspects of cinnamon written by experts in these fields, condenses current knowledge into a single source and contribute to the advancement and dissemination of knowledge and technology. Contributors to the book constitute internationally renowned senior scientists and academics with hands-on experience as well as movers and shakers of industry, thereby striking a right balance between theory and practice. Therefore it is a valuable source for students, teachers, scientists, planners policy makers, practicing agriculturists and industrialists, and a prized acquisition to any library in higher education institutions, R & D institutions and public and private sector institutions in agriculture and allied fields.

Academic Pain Medicine

Author : Yury Khelemsky
Publisher : Springer
ISBN 13 : 3030180050
Total Pages : 386 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Academic Pain Medicine by : Yury Khelemsky

Download or read book Academic Pain Medicine written by Yury Khelemsky and published by Springer. This book was released on 2019-07-23 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text is the definitive academic pain medicine resource for medical students, residents and fellows. Acting as both an introduction and continued reference for various levels of training, this guide provides practitioners with up-to-date academic standards. In order to comprehensively meet the need for such a contemporary text—treatment options, types of pain management, and variables affecting specific conditions are thoroughly examined across 48 chapters. Categories of pain conditions include orofacial, neuropathic, visceral, neck, acute, muscle and myofascial, chronic urogenital and pelvic, acute, and regional. Written by renowned experts in the field, each chapter is supplemented with high-quality color figures, tables and images that provide the reader with a fully immersive educational experience. Academic Pain Medicine: A Practical Guide to Rotations, Fellowship, and Beyond is an unprecedented contribution to the literature that addresses the wide-spread requisite for a practical guide to pain medicine within the academic environment.

Cancer Theranostics

Author : Xiaoyuan Chen
Publisher : Academic Press
ISBN 13 : 0124078842
Total Pages : 543 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Cancer Theranostics by : Xiaoyuan Chen

Download or read book Cancer Theranostics written by Xiaoyuan Chen and published by Academic Press. This book was released on 2014-03-20 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. - Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy - Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine - Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management

Breast Cancer Management for Surgeons

Author : Lynda Wyld
Publisher : Springer
ISBN 13 : 3319566733
Total Pages : 713 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Breast Cancer Management for Surgeons by : Lynda Wyld

Download or read book Breast Cancer Management for Surgeons written by Lynda Wyld and published by Springer. This book was released on 2017-11-29 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a comprehensive overview of the state of the art knowledge of breast cancer management for the modern breast surgeon. It covers all aspects of multidisciplinary care including primary breast and axillary surgery, reconstruction and oncoplastic techniques, external beam radiotherapy and newer techniques such as tomotherapy, intraoperative radiotherapy and brachytherapy. In addition, systemic therapies including chemotherapy, the latest biological targeted therapies and endocrine therapies are covered. Readers can find out about other important aspects of breast cancer such as genetics, screening, imaging and long-term health among others. Chapters take the reader through the basics up to the highest levels of knowledge in an easy to understand format with management algorithms to aid clinical care, generous referencing of the best literature and figures and photographs to illustrate each section. Published with the official approval of the European Society of Surgical Oncology (ESSO) and the European Society of Breast Cancer Specialists (EUSOMA), the book is written by a panel of recognised leaders in the field and is an indispensable guide for the practicing breast specialist and senior specialists in training, wishing to update their knowledge with the latest trends or polish off their training before accreditation.

Mohs Micrographic Surgery

Author : Keyvan Nouri
Publisher : Springer Science & Business Media
ISBN 13 : 144712152X
Total Pages : 558 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Mohs Micrographic Surgery by : Keyvan Nouri

Download or read book Mohs Micrographic Surgery written by Keyvan Nouri and published by Springer Science & Business Media. This book was released on 2012-02-15 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written for dermatologists, otolaryngologists, facial plastic surgeons and any physician who want to provide state of the art treatment for skin cancer patients. Considering the high incidence of non-melanoma skin cancers such as Basal Cell Carcinoma and Squamous Cell Carcinoma (accounting for over one million cases per year in the United States) and since Mohs Micrographic Surgery has become the treatment of choice for these skin cancers, the popularity of this technique has been increasing dramatically, worldwide.

Recent Advances in Natural Products Analysis

Author : Seyed Mohammad Nabavi
Publisher : Elsevier
ISBN 13 : 0128175192
Total Pages : 880 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Recent Advances in Natural Products Analysis by : Seyed Mohammad Nabavi

Download or read book Recent Advances in Natural Products Analysis written by Seyed Mohammad Nabavi and published by Elsevier. This book was released on 2020-03-07 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Natural Products Analysis is a thorough guide to the latest analytical methods used for identifying and studying bioactive phytochemicals and other natural products. Chemical compounds, such as flavonoids, alkaloids, carotenoids and saponins are examined, highlighting the many techniques for studying their properties. Each chapter is devoted to a compound category, beginning with the underlying chemical properties of the main components followed by techniques of extraction, purification and fractionation, and then techniques of identification and quantification. Biological activities, possible interactions, levels found in plants, the effects of processing, and current and potential industrial applications are also included. Focuses on the latest analytical techniques used for studying phytochemical and other biological compounds Authored and edited by the top worldwide experts in their field Discusses the current and potential applications and predicts future trends of each compound group

Plant and Human Health, Volume 2

Author : Munir Ozturk
Publisher : Springer
ISBN 13 : 3030033449
Total Pages : 703 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Plant and Human Health, Volume 2 by : Munir Ozturk

Download or read book Plant and Human Health, Volume 2 written by Munir Ozturk and published by Springer. This book was released on 2019-01-22 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early anthropological evidence for plant use as medicine is 60,000 years old as reported from the Neanderthal grave in Iraq. The importance of plants as medicine is further supported by archeological evidence from Asia and the Middle East. Today, around 1.4 billion people in South Asia alone have no access to modern health care, and rely instead on traditional medicine to alleviate various symptoms. On a global basis, approximately 50 to 80 thousand plant species are used either natively or as pharmaceutical derivatives for life-threatening conditions that include diabetes, hypertension and cancers. As the demand for plant-based medicine rises, there is an unmet need to investigate the quality, safety and efficacy of these herbals by the “scientific methods”. Current research on drug discovery from medicinal plants involves a multifaceted approach combining botanical, phytochemical, analytical, and molecular techniques. For instance, high throughput robotic screens have been developed by industry; it is now possible to carry out 50,000 tests per day in the search for compounds which act on a key enzyme or a subset of receptors. This and other bioassays thus offer hope that one may eventually identify compounds for treating a variety of diseases or conditions. However, drug development from natural products is not without its problems. Frequent challenges encountered include the procurement of raw materials, the selection and implementation of appropriate high-throughput bioassays, and the scaling-up of preparative procedures. Research scientists should therefore arm themselves with the right tools and knowledge in order to harness the vast potentials of plant-based therapeutics. The main objective of Plant and Human Health is to serve as a comprehensive guide for this endeavor. Volume 1 highlights how humans from specific areas or cultures use indigenous plants. Despite technological developments, herbal drugs still occupy a preferential place in a majority of the population in the third world and have slowly taken roots as alternative medicine in the West. The integration of modern science with traditional uses of herbal drugs is important for our understanding of this ethnobotanical relationship. Volume 2 deals with the phytochemical and molecular characterization of herbal medicine. Specifically, It will focus on the secondary metabolic compounds which afford protection against diseases. Lastly, Volume 3 focuses on the physiological mechanisms by which the active ingredients of medicinal plants serve to improve human health. Together this three-volume collection intends to bridge the gap for herbalists, traditional and modern medical practitioners, and students and researchers in botany and horticulture.

Nanopharmaceuticals: Principles and Applications Vol. 2

Author : Vinod Kumar Yata
Publisher : Springer Nature
ISBN 13 : 3030449211
Total Pages : 380 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Nanopharmaceuticals: Principles and Applications Vol. 2 by : Vinod Kumar Yata

Download or read book Nanopharmaceuticals: Principles and Applications Vol. 2 written by Vinod Kumar Yata and published by Springer Nature. This book was released on 2020-07-14 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the comprehensive description of basic principles, methodologies, similarities and differences of nano-liposomes and -phytosomes. It focuses on the implications of these nano carriers in drug delivery and also includes detailed classification of nanoinonized drug particles, polymeric nanoparticles and hydrophobic nanoparticles. This book concludes with the biological, technical and study-design challenges of Nanopharmaceuticals and presents critical viewpoints of smart DNA nanostructures. The risk factors and regulatory concerns have also been kept in focus and the book includes the toxicity and application of different types of ionic liquids for humans and environment. It also critically describes characteristics, applications and regulatory gaps of nanoparticle-ionic liquid combined systems.