Development And Application Of New Nmr Methodology To Study Structure And Dynamics Of Biological Macromolecules In Solution

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NMR with Biological Macromolecules in Solution

Author : Kurt Wüthrich
Publisher : World Scientific Publishing Company
ISBN 13 : 9789811235788
Total Pages : 270 pages
Book Rating : 4.2/5 (357 download)

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Book Synopsis NMR with Biological Macromolecules in Solution by : Kurt Wüthrich

Download or read book NMR with Biological Macromolecules in Solution written by Kurt Wüthrich and published by World Scientific Publishing Company. This book was released on 2021 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones.Key publications from the Kurt Wüthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome, metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones.

Biological NMR Spectroscopy

Author : John L. Markley
Publisher : Oxford University Press
ISBN 13 : 0195094689
Total Pages : 375 pages
Book Rating : 4.1/5 (95 download)

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Book Synopsis Biological NMR Spectroscopy by : John L. Markley

Download or read book Biological NMR Spectroscopy written by John L. Markley and published by Oxford University Press. This book was released on 1997-01-30 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.

NMR in Structural Biology

Author : Kurt Wthrich
Publisher : World Scientific
ISBN 13 : 9789810223847
Total Pages : 770 pages
Book Rating : 4.2/5 (238 download)

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Book Synopsis NMR in Structural Biology by : Kurt Wthrich

Download or read book NMR in Structural Biology written by Kurt Wthrich and published by World Scientific. This book was released on 1995 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume presents a survey of the research by Kurt Wthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.

Biomolecular NMR Spectroscopy

Author : Andrew J. Dingley
Publisher : IOS Press
ISBN 13 : 1607506947
Total Pages : 488 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis Biomolecular NMR Spectroscopy by : Andrew J. Dingley

Download or read book Biomolecular NMR Spectroscopy written by Andrew J. Dingley and published by IOS Press. This book was released on 2011 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterization of biomolecular structures at atomic resolution in the solution state. This timely book, entitled "Biomolecular NMR Spectroscopy," focuses on the latest state-of-the-art NMR techniques for characterization of biological macromolecules in the solid and solution state. The editors, Dr. Andrew Dingley (University of Auckland, New Zealand) and Dr. Steven Pascal (Massey University, New Zealand) have organized the book into four sections, covering the following topics: sample preparation, structure and dynamics of proteins, structure and dynamics of nucleic acids and protein-nucleic acid complexes, and rapid and hybrid techniques--

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

Author :
Publisher :
ISBN 13 :
Total Pages : 1064 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Biomedical Index to PHS-supported Research: pt. A. Subject access A-H by :

Download or read book Biomedical Index to PHS-supported Research: pt. A. Subject access A-H written by and published by . This book was released on 1992 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applications of NMR Spectroscopy: Volume 2

Author : Atta-ur Rahman
Publisher : Elsevier
ISBN 13 : 1608059650
Total Pages : 262 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Applications of NMR Spectroscopy: Volume 2 by : Atta-ur Rahman

Download or read book Applications of NMR Spectroscopy: Volume 2 written by Atta-ur Rahman and published by Elsevier. This book was released on 2015-12-10 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of NMR Spectroscopy, Volume 2, originally published by Bentham and now distributed by Elsevier, presents the latest developments in the field of NMR spectroscopy, including the analysis of plant polyphenols, the role of NMR spectroscopy in neuroradiology, NMR–based sensors, studies on protein and nucleic acid structure and function, and mathematical formations for NMR spectroscopy in structural biology. The fully illustrated chapters contain comprehensive references to the recent literature. The applications presented cover a wide range of the field, such as drug development, medical imaging and diagnostics, food science, mining, petrochemical, process control, materials science, and chemical engineering, making this resource a multi-disciplinary reference with broad applications. The content is ideal for readers who are seeking reviews and updates, as it consolidates scientific articles of a diverse nature into a single volume. Sections are organized based on disciplines, such as food science and medical diagnostics. Each chapter is written by eminent experts in the field. - Consolidates the latest developments in NMR spectroscopy into a single volume - Authored and edited by world-leading experts in spectroscopy - Features comprehensive references to the most recent related literature - More than 65 illustrations aid in the retention of key concepts

Research Awards Index

Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Scientific Report

Author : Scripps Research Institute
Publisher :
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Scientific Report by : Scripps Research Institute

Download or read book Scientific Report written by Scripps Research Institute and published by . This book was released on 2005 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Grants Index

Author : National Institutes of Health (U.S.). Division of Research Grants
Publisher :
ISBN 13 :
Total Pages : 1224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants

Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1975 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomedical Index to PHS-supported Research

Author :
Publisher :
ISBN 13 :
Total Pages : 1216 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Biomedical Index to PHS-supported Research by :

Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1995 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Marine Biomaterials

Author : Se-Kwon Kim
Publisher : CRC Press
ISBN 13 : 1466505648
Total Pages : 843 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Marine Biomaterials by : Se-Kwon Kim

Download or read book Marine Biomaterials written by Se-Kwon Kim and published by CRC Press. This book was released on 2013-04-11 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oceans are an abundant source of diverse biomaterials with potential for an array of uses. Marine Biomaterials: Characterization, Isolation and Applications brings together the wide range of research in this important area, including the latest developments and applications, from preliminary research to clinical trials. The book is divided into four parts, with chapters written by experts from around the world. Biomaterials described come from a variety of marine sources, such as fish, algae, microorganisms, crustaceans, and mollusks. Part I covers the isolation and characterization of marine biomaterials—bioceramics, biopolymers, fatty acids, toxins and pigments, nanoparticles, and adhesive materials. It also describes problems that may be encountered in the process as well as possible solutions. Part II looks at biological activities of marine biomaterials, including polysaccharides, biotoxins, and peptides. Chapters examine health benefits of the biomaterials, such as antiviral activity, antidiabetic properties, anticoagulant and anti-allergic effects, and more. Part III discusses biomedical applications of marine biomaterials, including nanocomposites, and describes applications of various materials in tissue engineering and drug delivery. Part IV explores commercialization of marine-derived biomaterials—marine polysaccharides and marine enzymes—and examines industry perspectives and applications. This book covers the key aspects of available marine biomaterials for biological and biomedical applications, and presents techniques that can be used for future isolation of novel materials from marine sources.

Postdoctoral Research Fellowship Opportunities

Author : National Institutes of Health (U.S.)
Publisher :
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Postdoctoral Research Fellowship Opportunities by : National Institutes of Health (U.S.)

Download or read book Postdoctoral Research Fellowship Opportunities written by National Institutes of Health (U.S.) and published by . This book was released on 1995 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nuclear Magnetic Resonance

Author : G. A. Webb
Publisher : Royal Society of Chemistry
ISBN 13 : 085404115X
Total Pages : 387 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Nuclear Magnetic Resonance by : G. A. Webb

Download or read book Nuclear Magnetic Resonance written by G. A. Webb and published by Royal Society of Chemistry. This book was released on 2008-03-31 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage.

Experimental Approaches of NMR Spectroscopy

Author : The Nuclear Magnetic Resonance Society of Japan
Publisher : Springer
ISBN 13 : 9811059667
Total Pages : 634 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Experimental Approaches of NMR Spectroscopy by : The Nuclear Magnetic Resonance Society of Japan

Download or read book Experimental Approaches of NMR Spectroscopy written by The Nuclear Magnetic Resonance Society of Japan and published by Springer. This book was released on 2017-11-23 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.

Methods in Molecular Biophysics

Author : Igor N. Serdyuk
Publisher : Cambridge University Press
ISBN 13 : 1107056373
Total Pages : 709 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Methods in Molecular Biophysics by : Igor N. Serdyuk

Download or read book Methods in Molecular Biophysics written by Igor N. Serdyuk and published by Cambridge University Press. This book was released on 2017-05-18 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive graduate textbook explaining key physical methods in biology, reflecting the very latest research in this fast-moving field.

Advances in Protein Molecular and Structural Biology Methods

Author : Timir Tripathi
Publisher : Academic Press
ISBN 13 : 0323902650
Total Pages : 716 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advances in Protein Molecular and Structural Biology Methods by : Timir Tripathi

Download or read book Advances in Protein Molecular and Structural Biology Methods written by Timir Tripathi and published by Academic Press. This book was released on 2022-01-14 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. - Presents a thorough overview of the latest and emerging methods and technologies for protein study - Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy - Includes computational and machine learning methods - Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins

Brenner's Encyclopedia of Genetics

Author : Stanley Maloy
Publisher : Academic Press
ISBN 13 : 0080961568
Total Pages : 4360 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Brenner's Encyclopedia of Genetics by : Stanley Maloy

Download or read book Brenner's Encyclopedia of Genetics written by Stanley Maloy and published by Academic Press. This book was released on 2013-03-03 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics