Developing Concurrent Transcranial Magnetic Stimulation and Electroencephalography to Study Prefrontal Cortex Neurophysiology in People with Schizophrenia

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Publisher :
ISBN 13 :
Total Pages : 482 pages
Book Rating : 4.:/5 (11 download)

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Book Synopsis Developing Concurrent Transcranial Magnetic Stimulation and Electroencephalography to Study Prefrontal Cortex Neurophysiology in People with Schizophrenia by : Nigel Rogasch

Download or read book Developing Concurrent Transcranial Magnetic Stimulation and Electroencephalography to Study Prefrontal Cortex Neurophysiology in People with Schizophrenia written by Nigel Rogasch and published by . This book was released on 2013 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cognitive impairment such as deficits in working memory - the ability to retain and manipulate information over a brief period - are core features of schizophrenia. Such deficits may result from dysfunctional cortical inhibition in the dorsolateral prefrontal cortex (DLPFC). One method potentially suited to studying inhibitory circuits in the DLPFC is concurrent transcranial magnetic stimulation and electroencephalography (TMS-EEG). Merging these methods is technically challenging, resulting in artifacts which obscure recording of TMS-evoked neural activity. Furthermore, little is known about the mechanisms that underlie TMS-evoked cortical potentials (TEPs) from the DLPFC. The broad aim of this thesis was to develop and validate TMS-EEG methods to study DLPFC neurophysiology in people with and without schizophrenia.Five studies are reported. The first describes EEG artifacts following TMS. Phantom heads (melons) and human participants were used to investigate the effects of different experimental arrangements (stimulators, pulse types, stimulation site, intensity, paired-pulse conditions) on TMS-evoked EEG artifacts. This study demonstrated the pervasive nature of TMS-evoked scalp muscle artifacts over the DLPFC.In the second study, independent component analysis (ICA - a method of blind source separation) was assessed to identify and remove artifacts from EEG recordings following TMS over the DLPFC. Five sub-types of artifact were identified including muscle, blink and auditory artifacts. We provided evidence that each of these artifacts could be removed with reasonable confidence using ICA, revealing otherwise obscured TMS-evoked neural activity. In study three and four we examined the underlying mechanisms of TEPs. We compared suppression of TEPs with motor evoked potentials (MEPs) following long-interval cortical inhibition (LICI - a paired-pulse TMS paradigm) over the motor cortex (study three) and variations in TEP LICI over the DLPFC between individuals (study four). We demonstrated that modulation of LICI strength differed between TEP peaks, suggesting early peaks (P30, N40) reflected excitatory neurotransmission, whereas latter peaks (N100) reflected the inhibitory mechanism responsible for LICI. In the final study, we compared TMS-evoked DLPFC network properties between people with and without schizophrenia. People with schizophrenia displayed a reduced N100 and reduced TMS-evoked high frequency oscillations in fronto-parietal and interhemispheric networks compared with controls. Importantly, TMS-evoked gamma oscillations (30-45 Hz; dependent on cortical inhibition) in the DLPFC were particularly reduced in a sub-group of schizophrenia participants with low working memory capacity. These findings support impaired inhibitory neurotransmission in the DLPFC of people with schizophrenia and suggest the ability of the DLPFC to generate high frequency oscillations may contribute to schizophrenia-related working memory deficits.This thesis describes the application of TMS-EEG to study cortical neurophysiology in both healthy and disease states. The findings demonstrate that TMS-evoked neural activity can be recorded from the DLPFC following artifact removal and provide insight into inhibitory mechanisms within the DLPFC. Moreover, alterations in DLPFC function assessed using TMS-EEG may underlie reduced working memory capacity in people with schizophrenia. These findings have significant implications for the development of TMS-EEG as a neurophysiological technique, our knowledge of inhibitory mechanisms in the human cortex and our understanding of working memory deficits in schizophrenia.

A Clinical Guide to Transcranial Magnetic Stimulation

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Publisher : Oxford University Press
ISBN 13 : 019936849X
Total Pages : 194 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis A Clinical Guide to Transcranial Magnetic Stimulation by : Paul E. Holtzheimer

Download or read book A Clinical Guide to Transcranial Magnetic Stimulation written by Paul E. Holtzheimer and published by Oxford University Press. This book was released on 2014-02-21 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Clinical Guide serves as a reference tool for clinicians in the administration of transcranial magnetic stimulation (TMS) for neuropsychiatric disorders. The primary intent of this Guide is to focus on the clinical applications of TMS and to offer detailed information on the safe and effective administration of TMS with consideration of the neurophysiological effects particularly in relation to safety, targeting specific cortical areas and practical issues such as the length of treatment sessions and the durability of the TMS response. The Guide focuses on the evidenced based literature and utilizes this literature to inform specific recommendations on the use of rTMS in a clinical setting. The efficacy and safety of TMS for neuropsychiatric disorders, including its use in special populations, such as the elderly, will be reviewed to facilitate clinical decision-making. The Guide will also outline setting up a TMS service including practical issues such as considerations for the qualifications of the person administering the treatment, the use of concomitant medications, what equipment is necessary to have in the treatment room and monitoring the outcomes to treatment. The Guide is intended to be a practical reference for the practicing clinician in the safe and effective administration of TMS.

Oxford Handbook of Transcranial Stimulation

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Publisher : Oxford University Press
ISBN 13 : 0198568924
Total Pages : 773 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Oxford Handbook of Transcranial Stimulation by : Eric Wassermann

Download or read book Oxford Handbook of Transcranial Stimulation written by Eric Wassermann and published by Oxford University Press. This book was released on 2008-01-24 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcranial stimulation comprises an important set of techniques for investigating brain function, some of which promise to treat diseases. This book provides a review of the scientific and technical background required to understand transcranial stimulation, for neuroscientists, neurologists, and psychiatrists.

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences

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Publisher : Springer Nature
ISBN 13 : 3030433560
Total Pages : 365 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences by : Bernardo Dell'Osso

Download or read book Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences written by Bernardo Dell'Osso and published by Springer Nature. This book was released on 2020-07-31 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.

Clinical Neurophysiology, Neuroimaging, and Neuromodulation of Neuropsychiatric Disorders

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Author :
Publisher : Mdpi AG
ISBN 13 : 9783036531311
Total Pages : 252 pages
Book Rating : 4.5/5 (313 download)

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Book Synopsis Clinical Neurophysiology, Neuroimaging, and Neuromodulation of Neuropsychiatric Disorders by : Yoshihiro Noda

Download or read book Clinical Neurophysiology, Neuroimaging, and Neuromodulation of Neuropsychiatric Disorders written by Yoshihiro Noda and published by Mdpi AG. This book was released on 2022-02-07 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, as suggested by Dr. György Buzsáki, such ideas as "Without the rhythm of the brain, the mind is not born" and "The brain is a device that predicts, and it is the rhythm of the brain that produces predictive ability" have come to be accepted. In this context, we have organized a Special Issue presenting the cutting-edge research in clinical neurophysiology, neuroimaging, and neuromodulation.

A Practical Guide to Transcranial Magnetic Stimulation Neurophysiology and Treatment Studies

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Publisher : Oxford University Press
ISBN 13 : 0199335842
Total Pages : 337 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis A Practical Guide to Transcranial Magnetic Stimulation Neurophysiology and Treatment Studies by : Robert Chen

Download or read book A Practical Guide to Transcranial Magnetic Stimulation Neurophysiology and Treatment Studies written by Robert Chen and published by Oxford University Press. This book was released on 2022 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcranial magnetic stimulation (TMS) is a widely used non-invasive brain stimulation technique. It represents an exciting new frontier in neuroscience research and can be used to examine neural processes, providing insights into pathophysiology and treating a variety of neuropsychiatric illnesses. A Practical Guide to Transcranial Magnetic Stimulation Neurophysiology and Treatment Studies presents an overview of the use of TMS as both an investigational tool and as treatment for neurological and psychiatric disorders. The chapters include an overview of the history and basic principles of TMS and repetitive TMS (rTMS), the different types of TMS coils, different stimulation approaches, the use of neuronavigation, and safety considerations. The utility of single and paired TMS techniques to measure cortical inhibition, facilitation, connectivity and reactivity in motor and non-motor brain areas, the different methods of using TMS to induce brain plasticity, and use of TMS in cognitive studies are explored. It also covers TMS and rTMS combined with electroencephalography (EEG) in neurophysiological studies. The authors provide a summary of the clinical applications of TMS in neurological and psychiatric disorders including depression, schizophrenia, stroke, Parkinson disease, and pain. This up-to-date volume provides a compendious review of the use of TMS and rTMS that will help guide the utility of this methodology in both clinical and research settings. This practical guide will be a useful resource for those new to the field, as well as experienced users, for both research and clinical settings.

Navigated Transcranial Magnetic Stimulation in Neurosurgery

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Publisher : Springer
ISBN 13 : 3319549189
Total Pages : 301 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Navigated Transcranial Magnetic Stimulation in Neurosurgery by : Sandro M. Krieg

Download or read book Navigated Transcranial Magnetic Stimulation in Neurosurgery written by Sandro M. Krieg and published by Springer. This book was released on 2017-07-03 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive work summarizing the advances that have been made in the neurosurgical use of navigated transcranial magnetic stimulation (nTMS) over the past ten years. Having increasingly gained acceptance as a presurgical mapping modality in neurosurgery, today it is widely used for preoperative mapping of cortical motor and language function, risk stratification and improving the accuracy of subcortical fiber bundle visualization. This unique work will provide neurosurgeons and neuroscientists who are starting their nTMS program essential and detailed information on the technique and protocols, as well as the current clinical evidence on and limitations of the various applications of nTMS. At the same time, more experienced nTMS users looking for deeper insights into nTMS mapping and treatment in neurosurgery will find clearly structured, accessible information. The book was prepared by an international mix of authors, each of which was chosen for their status as a respected expert on the respective subtopic, as evinced by their landmark publications on nTMS.

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders

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Publisher : Springer
ISBN 13 : 3319339672
Total Pages : 421 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Transcranial Direct Current Stimulation in Neuropsychiatric Disorders by : André Brunoni

Download or read book Transcranial Direct Current Stimulation in Neuropsychiatric Disorders written by André Brunoni and published by Springer. This book was released on 2016-09-12 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide a comprehensive review of the use of Transcranial Direct Current Stimulation (tDCS) in different psychiatric conditions. Here we review tDCS clinical studies employing different types of design (from single-session tDCS studies to randomized clinical trials) as well as studies evaluating the impact of tDCS in neurophysiological, behavioral and brain imaging outcomes. Although the understanding about physiological foundations and effectiveness of clinical therapies of psychiatric diseases has been considerably increased during the last decades, our knowledge is still limited, and consequently psychiatric diseases are still a major burden to the individual patient and society. Recently, interest in pathological alterations of neuroplasticity in psychiatric diseases as a critical condition for development, and amelioration of clinical symptoms increased, caused by the fact that new tools, such as functional imaging, and brain stimulation techniques do allow to monitor, and modulate these phenomena in humans. Especially non-invasive brain stimulation techniques evolved as an attractive potential new therapeutic tool. The interest in non-invasive brain stimulation has grown exponentially in the past 25 years, with the development of non-pharmacological, neuromodulatory techniques such as tDCS and repetitive transcranial magnetic stimulation (rTMS). TDCS, although even newer than rTMS, has attracted considerable attention in both basic and clinical research scenarios. In the context of clinical research, tDCS is being increasingly investigated as a novel treatment tool for several psychiatric disorders, such as major depression, schizophrenia and neurocognitive and substance abuse disorders. Transcranial Direct Current Stimulation in Neuropsychiatric Disorders – Clinical Principles and Management intends to serve as a practical guide on the field, attracting the interest of psychiatrists, neurologists and neuroscientists with little or no experience with tDCS, as well as those with a background on tDCS who want to increase their knowledge in any particular psychiatric condition.

Magnetic Stimulation in Clinical Neurophysiology

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Author :
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Magnetic Stimulation in Clinical Neurophysiology by : Mark Hallett

Download or read book Magnetic Stimulation in Clinical Neurophysiology written by Mark Hallett and published by Butterworth-Heinemann. This book was released on 2005 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and updated 2nd Edition of this unique resource comprehensively covers the diagnostic and clinical applications of transcranial magnetic stimulation (TMS). A team of internationally renowned authorities offer cutting-edge, in-depth guidance on the use of TMS to study brain physiology and pathophysiology as well as its current and future therapeutic uses. Readers will find the essential up-to-date information they need to make the most of this dynamic method-all in one authoritative resource.

Neuroimaging and Neurophysiology in Psychiatry

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Publisher : Oxford University Press
ISBN 13 : 0198739605
Total Pages : 161 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Neuroimaging and Neurophysiology in Psychiatry by : David Linden

Download or read book Neuroimaging and Neurophysiology in Psychiatry written by David Linden and published by Oxford University Press. This book was released on 2016 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimaging and Neurophysiology in Psychiatry is an invaluable guide through the methods and applications of neuroimaging and neurophysiology.

Practical Guide to Transcranial Direct Current Stimulation

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Publisher : Springer
ISBN 13 : 3319959484
Total Pages : 651 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Practical Guide to Transcranial Direct Current Stimulation by : Helena Knotkova

Download or read book Practical Guide to Transcranial Direct Current Stimulation written by Helena Knotkova and published by Springer. This book was released on 2019-01-23 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview on Transcranial Direct Current Stimulation (tDCS) and the clinical applications of this promising technique. Separated into three parts, the book begins with basic principles, mechanisms and approaches of tDCS. This is followed by a step-by-step practicum, methodological considerations and ethics and professional conduct pertaining to this novel technique. Chapters are authored by renowned experts who also direct and plan tDCS educational events worldwide. Bridging the existing gap in instructional materials for tDCS while addressing growing interest in education in this field, professionals within a broad range of medical disciplines will find this text to be an invaluable guide.

A Clinical Guide to Transcranial Magnetic Stimulation

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Publisher : Oxford University Press, USA
ISBN 13 : 0199926484
Total Pages : 194 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis A Clinical Guide to Transcranial Magnetic Stimulation by : Paul E. Holtzheimer

Download or read book A Clinical Guide to Transcranial Magnetic Stimulation written by Paul E. Holtzheimer and published by Oxford University Press, USA. This book was released on 2014 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Clinical Guide serves as a reference tool for clinicians in the administration of transcranial magnetic stimulation (TMS) for neuropsychiatric disorders. The primary intent of this Guide is to focus on the clinical applications of TMS and to offer detailed information on the safe and effective administration of TMS with consideration of the neurophysiological effects particularly in relation to safety, targeting specific cortical areas and practical issues such as the length of treatment sessions and the durability of the TMS response. The Guide focuses on the evidenced based literature and utilizes this literature to inform specific recommendations on the use of rTMS in a clinical setting. The efficacy and safety of TMS for neuropsychiatric disorders, including its use in special populations, such as the elderly, will be reviewed to facilitate clinical decision-making. The Guide will also outline setting up a TMS service including practical issues such as considerations for the qualifications of the person administering the treatment, the use of concomitant medications, what equipment is necessary to have in the treatment room and monitoring the outcomes to treatment. The Guide is intended to be a practical reference for the practicing clinician in the safe and effective administration of TMS.

Neuromodulation in Psychiatry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118801040
Total Pages : 518 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Neuromodulation in Psychiatry by : Clement Hamani

Download or read book Neuromodulation in Psychiatry written by Clement Hamani and published by John Wiley & Sons. This book was released on 2016-01-26 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by an expert multidisciplinary team, Neuromodulation in Psychiatry is the first reference guide to address both invasive and non-invasive neuromodulation strategies used in psychiatry. Covers basic principles, technical aspects, clinical applications and ethical considerations Presents up-to-date evidence in comprehensive summaries suitable for all levels of experience Each technique is clearly explained along with its implications for real-world clinical practice Allows psychiatrists to make informed decisions regarding neuromodulation for their patients

Handbook of Transcranial Magnetic Stimulation

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Author :
Publisher : CRC Press
ISBN 13 : 9780340720097
Total Pages : 416 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Handbook of Transcranial Magnetic Stimulation by : Alvaro Pascual-Leone

Download or read book Handbook of Transcranial Magnetic Stimulation written by Alvaro Pascual-Leone and published by CRC Press. This book was released on 2001-11-30 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcranial Magnetic Stimul0tion (TMS) is a non-invasive technique that has revolutionised the study of the human nervous system allowing in-depth investigations of complex voluntary motor control pathways. Today, many of the techniques used in TMS have become routine in clinical electrophysiological assessments. As an investigative tool, its application ranges from clinical diagnostics to cognitive research. Now the use of repetitive TMS (rTMS) is gaining support amongst psychiatrists as evidence suggests that it may provide an alternative to ECT in treating depression and other psychiatric disorders. This handbook brings together the basic science, fundamental principles, and essential procedures of TMS needed by all those useing or planning to use the technique clinically or in research. The final two sections focus upon current up to date knowledge of applications of the technique. Written in a digestible style by world authorities in different related specialties, the Handbook of TMS will be a valuable and comprehensive guide for clinical neurophysiologists, neuropsychiatrists, neurologists and psychiatrists.

The Cognitive Neuroscience of Working Memory

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Author :
Publisher :
ISBN 13 : 0198570392
Total Pages : 418 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis The Cognitive Neuroscience of Working Memory by : Naoyuki Osaka

Download or read book The Cognitive Neuroscience of Working Memory written by Naoyuki Osaka and published by . This book was released on 2007 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only relatively recently that it has been possible to study the neural processes that might underlie working memory, leading to a proliferation of research in this domain. This volume brings together leading researchers from around the world to summarise current knowledge of this field.

The Routledge Handbook of Philosophy of Skill and Expertise

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Publisher : Routledge
ISBN 13 : 1351720422
Total Pages : 1059 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis The Routledge Handbook of Philosophy of Skill and Expertise by : Ellen Fridland

Download or read book The Routledge Handbook of Philosophy of Skill and Expertise written by Ellen Fridland and published by Routledge. This book was released on 2020-08-20 with total page 1059 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophical questions surrounding skill and expertise can be traced back as far as Ancient Greece, China, and India. In the twentieth century, skilled action was an important factor in the work of phenomenologists such as Heidegger and Merleau-Ponty and analytic philosophers including Gilbert Ryle. However, as a subject in its own right it has, until now, remained largely in the background. The Routledge Handbook of Philosophy of Skill and Expertise is an outstanding reference source and the first major collection of its kind, reflecting the explosion of interest in the topic in recent years. Comprising thirty-nine chapters written by leading international contributors, the Handbook is organized into six clear parts: • Skill in the history of philosophy (East and West) • Skill in epistemology • Skill, intelligence, and agency • Skill in perception, imagination, and emotion • Skill, language, and social cognition • Skill and expertise in normative philosophy. Essential reading for students and researchers in philosophy of mind and psychology, epistemology, and ethics, The Routledge Handbook of Philosophy of Skill and Expertise is also suitable for those in related disciplines such as social psychology and cognitive science. It is also relevant to those who are interested in conceptual issues underlying skill and expertise in fields such as sport, the performing arts, and medicine.

The Neurobiology of the Prefrontal Cortex

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199552916
Total Pages : 422 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis The Neurobiology of the Prefrontal Cortex by : Richard E. Passingham

Download or read book The Neurobiology of the Prefrontal Cortex written by Richard E. Passingham and published by Oxford University Press. This book was released on 2012-07-12 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prefrontal cortex makes up almost a quarter of the human brain. The Neurobiology of the Prefrontal Cortex presents a new theory about its fundamental function. Written by two leading brain scientists, it is an important contribution to our understanding of the evolution and functioning of the human brain.