Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Design Synthesis And Single Molecule Force Spectroscopy Of Biosynthetic Polypeptides full books in PDF, epub, and Kindle. Read online Design Synthesis And Single Molecule Force Spectroscopy Of Biosynthetic Polypeptides ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Marie Asano
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (967 download)
Download or read book Design, Synthesis and Single Molecule Force Spectroscopy of Biosynthetic Polypeptides written by Marie Asano and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul Lloyd-Williams
Publisher : CRC Press
ISBN 13 : 9780849391422
Total Pages : 306 pages
Book Rating : 4.3/5 (914 download)
Download or read book Chemical Approaches to the Synthesis of Peptides and Proteins written by Paul Lloyd-Williams and published by CRC Press. This book was released on 1997-04-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.
Author : David B. Weiner
Publisher : CRC Press
ISBN 13 : 9780877629351
Total Pages : 382 pages
Book Rating : 4.6/5 (293 download)
Download or read book Biologically Active Peptides written by David B. Weiner and published by CRC Press. This book was released on 1993-11-04 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Investigation into basic and advanced peptide design, synthesis, evaluation and utilization. New therapeutic approaches from experimental systems.
Author : Fernando Albericio
Publisher : CRC Press
ISBN 13 : 9780824703592
Total Pages : 852 pages
Book Rating : 4.7/5 (35 download)
Download or read book Solid-Phase Synthesis written by Fernando Albericio and published by CRC Press. This book was released on 2000-04-28 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the information needed to synthesize peptides by solid-phase synthesis (SPS) - employing polymeric support (resins), anchoring linkages (handles), coupling reagents (activators), and protection schemes. It presents strategies for creating a wide variety of compounds for drug discovery and analyzes peptides, DNA, carbohydrates, conjugates of biomolecules, and small molecules.
Author : Knud Jensen
Publisher : John Wiley & Sons
ISBN 13 : 9780470749715
Total Pages : 306 pages
Book Rating : 4.7/5 (497 download)
Download or read book Peptide and Protein Design for Biopharmaceutical Applications written by Knud Jensen and published by John Wiley & Sons. This book was released on 2009-09-01 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides serve as effective drugs in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this researchers are developing new methods to create ‘tailor-made’ peptides and proteins with improved pharmacological properties. Design of Peptides and Proteins provides an overview of the experimental and computational methods for peptide and protein design, with an emphasis on specific applications for therapeutics and biomedical research. Topics covered include: Computer modeling of peptides and proteins Peptidomimetics Design and synthesis of cyclic peptides Carbohydrates in peptide and protein design De novo design of peptides and proteins Medical development applications An extended case study – the design of insulin variants Design of Peptides and Proteins presents the state-of-the-art of this exciting approach for therapeutics, with contributions from international experts. It is an essential resource for academic and industrial scientists in the fields of peptide and protein drug design, biomedicine, biochemistry, biophysics, molecular modelling, synthetic organic chemistry and medicinal/pharmaceutical chemistry.
Author : John Howl
Publisher : Springer Science & Business Media
ISBN 13 : 1592598773
Total Pages : 263 pages
Book Rating : 4.5/5 (925 download)
Download or read book Peptide Synthesis and Applications written by John Howl and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.
Author : Vibin Ramakrishnan
Publisher : Springer Nature
ISBN 13 : 1071634054
Total Pages : 142 pages
Book Rating : 4.0/5 (716 download)
Download or read book Biophysical Characterization of Functional Peptides written by Vibin Ramakrishnan and published by Springer Nature. This book was released on 2023-08-02 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This protocol book presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.
Author : Gregg B. Fields
Publisher : Academic Press
ISBN 13 :
Total Pages : 828 pages
Book Rating : 4.X/5 (4 download)
Download or read book Solid-Phase Peptide Synthesis written by Gregg B. Fields and published by Academic Press. This book was released on 1997-10-21 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features * Solid-phase peptide synthesis * Applications of peptides for structural and biological studies * Characterization of synthetic peptides
Author : Susanne Olofsson
Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.3/5 (91 download)
Download or read book Design, Synthesis, Structure, and Dynamics of a Polypeptide with Supersecondary Structure written by Susanne Olofsson and published by . This book was released on 1994 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Luca D. D'Andrea
Publisher :
ISBN 13 : 9781119044116
Total Pages : pages
Book Rating : 4.0/5 (441 download)
Download or read book Chemical Ligation written by Luca D. D'Andrea and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bushra Siddique
Publisher :
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.:/5 (612 download)
Download or read book Design, Synthesis and Characterization of a Series of Self-assembling Polypeptides written by Bushra Siddique and published by . This book was released on 2007 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: A series of polypeptides with well-defined sequences, (Asp3Phe1)n, (Asp2Phe1)n, (Asp1Phe1)n, (Asp1Phe2)n, and (Asp1Phe3)n, containing the hydrophilic amino acid, aspartic acid (Asp) and the hydrophobic amino acid, phenylalanine (Phe), were synthesized. Their behaviour in aqueous solution was investigated by performing fluorescence quenching and non-radiative energy transfer (NRET) experiments which were complemented by dynamic (DLS) and static (SLS) light scattering. The photophysical properties of the polypeptides were dependent on their Phe content. An increase in the Phe content led to an increase in the extinction coefficient, fluorescence quantum yield, and fluorescence average lifetime of the polypeptides. Circular dichroism experiments revealed that except for the (Asp1Phe3)n polypeptide, which adopts an alpha-helical conformation in aqueous solution, the other polypeptides did not adopt any known conformation in solution. The fluorescence quenching studies performed using molecular pyrene physically bound to the polypeptide via hydrophobic interactions resulted in protective quenching for the (Asp1Phe1)n, (Asp1Phe2)n, and (Asp1Phe3)n polypeptides, with some pyrenes having a lifetime of ~300 ns. Evidence for protective quenching was also observed in the polypeptides richer in Phe, when pyrene was covalently attached onto the polypeptides. However pyrene was found to be fully exposed to the quencher solution for the more hydrophilic polypeptides. The presence of NRET between a naphthalene labeled polypeptide and a pyrene labeled polypeptide for the (Asp1Phe2)n and (Asp1Phe3)n polypeptides and its absence for the (Asp3Phe1)n, (Asp2Phe1)n, and (Asp1Phe1)n polypeptides led to the conclusion that those polypeptides richer in Phe generate interpolymeric aggregates which provide protection to a hydrophobic cargo like molecular pyrene whereas the hydrophilic polypeptides exist predominantly as unimolecular micelles. These results were confirmed by DLS and SLS experiments.
Author :
Publisher : Elsevier
ISBN 13 : 0443218145
Total Pages : 398 pages
Book Rating : 4.4/5 (432 download)
Download or read book Peptide and Peptide Mimicking Tools: Methods, Synthesis, Design & Applications written by and published by Elsevier. This book was released on 2024-06-15 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide Chemical Tools for Modulating Biology, Volume 698 in the esteemed Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting topics on Peptide tools that target telomere maintenance, Molecular Design of Peptide Therapeutics, Sulfonyl peptide tools for modulating biology, Peptide tools for targeting the Crk/CrkL-p130Cas axis, Quorum sensing peptide tools, In vivo stability and BBB penetration of peptide tools, and Oligo-benzamide-based peptide mimicking tools for modulating biology.
Author : Matthew S. Lamm
Publisher : ProQuest
ISBN 13 : 9780549388920
Total Pages : pages
Book Rating : 4.3/5 (889 download)
Download or read book Molecular Self-assembly written by Matthew S. Lamm and published by ProQuest. This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 2432 pages
Book Rating : 4.:/5 (319 download)
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author : N. Leo Benoiton
Publisher : CRC Press
ISBN 13 : 1420027697
Total Pages : 304 pages
Book Rating : 4.4/5 (2 download)
Download or read book Chemistry of Peptide Synthesis written by N. Leo Benoiton and published by CRC Press. This book was released on 2016-04-19 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to generate the most desirable reactions. Incorporating elements from the author's role of Career Investigator of the Medical Research Council of Canada and his extensive teaching career, the book emphasizes learning rather th
Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)
Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Peter Hinterdorfer
Publisher : Springer Science & Business Media
ISBN 13 : 0387764976
Total Pages : 634 pages
Book Rating : 4.3/5 (877 download)
Download or read book Handbook of Single-Molecule Biophysics written by Peter Hinterdorfer and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.
