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Design And Testing Of Digital Microfluidic Biochips
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Book Synopsis Design and Testing of Digital Microfluidic Biochips by : Krishnendu Chakrabarty
Download or read book Design and Testing of Digital Microfluidic Biochips written by Krishnendu Chakrabarty and published by . This book was released on 2012-08-31 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive methodology for automated design, test and diagnosis, and use of robust, low-cost, and manufacturable digital microfluidic systems. It focuses on the development of a comprehensive CAD optimization framework for digital microfluidic biochips that unifies different design problems. With the increase in system complexity and integration levels, biochip designers can utilize the design methods described in this book to evaluate different design alternatives, and carry out design-space exploration to obtain the best design point.
Book Synopsis Design and Testing of Digital Microfluidic Biochips by : Yang Zhao
Download or read book Design and Testing of Digital Microfluidic Biochips written by Yang Zhao and published by Springer Science & Business Media. This book was released on 2012-07-25 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive methodology for automated design, test and diagnosis, and use of robust, low-cost, and manufacturable digital microfluidic systems. It focuses on the development of a comprehensive CAD optimization framework for digital microfluidic biochips that unifies different design problems. With the increase in system complexity and integration levels, biochip designers can utilize the design methods described in this book to evaluate different design alternatives, and carry out design-space exploration to obtain the best design point.
Book Synopsis Digital Microfluidic Biochips by : Krishnendu Chakrabarty
Download or read book Digital Microfluidic Biochips written by Krishnendu Chakrabarty and published by CRC Press. This book was released on 2018-10-03 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.
Book Synopsis Digital Microfluidic Biochips by : Krishnendu Chakrabarty
Download or read book Digital Microfluidic Biochips written by Krishnendu Chakrabarty and published by CRC Press. This book was released on 2010-05-03 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics-based biochips combine electronics with biochemistry, providing access to new application areas in a wide variety of fields. Continued technological innovations are essential to assuring the future role of these chips in functional diversification in biotech, pharmaceuticals, and other industries.Revolutionary guidance on design, opti
Book Synopsis Micro-Electrode-Dot-Array Digital Microfluidic Biochips by : Zipeng Li
Download or read book Micro-Electrode-Dot-Array Digital Microfluidic Biochips written by Zipeng Li and published by Springer. This book was released on 2018-12-14 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.
Book Synopsis Fault-Tolerant Digital Microfluidic Biochips by : Paul Pop
Download or read book Fault-Tolerant Digital Microfluidic Biochips written by Paul Pop and published by Springer. This book was released on 2015-09-07 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes for researchers in the fields of compiler technology, design and test, and electronic design automation the new area of digital microfluidic biochips (DMBs), and thus offers a new application area for their methods. The authors present a routing-based model of operation execution, along with several associated compilation approaches, which progressively relax the assumption that operations execute inside fixed rectangular modules. Since operations can experience transient faults during the execution of a bioassay, the authors show how to use both offline (design time) and online (runtime) recovery strategies. The book also presents methods for the synthesis of fault-tolerant application-specific DMB architectures. · Presents the current models used for the research on compilation and synthesis techniques of DMBs in a tutorial fashion; · Includes a set of “benchmarks”, which are presented in great detail and includes the source code of most of the techniques presented, including solutions to the basic compilation and synthesis problems; · Discusses several new research problems in detail, using numerous examples.
Book Synopsis Hardware/Software Co-Design and Optimization for Cyberphysical Integration in Digital Microfluidic Biochips by : Yan Luo
Download or read book Hardware/Software Co-Design and Optimization for Cyberphysical Integration in Digital Microfluidic Biochips written by Yan Luo and published by Springer. This book was released on 2014-08-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes a comprehensive framework for hardware/software co-design, optimization, and use of robust, low-cost, and cyberphysical digital microfluidic systems. Readers with a background in electronic design automation will find this book to be a valuable reference for leveraging conventional VLSI CAD techniques for emerging technologies, e.g., biochips or bioMEMS. Readers from the circuit/system design community will benefit from methods presented to extend design and testing techniques from microelectronics to mixed-technology microsystems. For readers from the microfluidics domain, this book presents a new design and development strategy for cyberphysical microfluidics-based biochips suitable for large-scale bioassay applications. • Takes a transformative, “cyberphysical” approach towards achieving closed-loop and sensor feedback-driven biochip operation under program control; • Presents a “physically-aware” system reconfiguration technique that uses sensor data at intermediate checkpoints to dynamically reconfigure biochips; • Enables readers to simplify the structure of biochips, while facilitating the “general-purpose” use of digital microfluidic biochips for a wider range of applications.
Book Synopsis Exact Design of Digital Microfluidic Biochips by : Oliver Keszocze
Download or read book Exact Design of Digital Microfluidic Biochips written by Oliver Keszocze and published by Springer. This book was released on 2018-06-11 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents exact, that is minimal, solutions to individual steps in the design process for Digital Microfluidic Biochips (DMFBs), as well as a one-pass approach that combines all these steps in a single process. All of the approaches discussed are based on a formal model that can easily be extended to cope with further design problems. In addition to the exact methods, heuristic approaches are provided and the complexity classes of various design problems are determined. Presents exact methods to tackle a variety of design problems for Digital Microfluidic Biochips (DMFBs); Describes an holistic, one-pass approach solving different design steps all at once; Based on a formal model of DMFBs that is easily adaptable to deal with further design tasks.
Book Synopsis Computer-Aided Design of Microfluidic Very Large Scale Integration (mVLSI) Biochips by : Kai Hu
Download or read book Computer-Aided Design of Microfluidic Very Large Scale Integration (mVLSI) Biochips written by Kai Hu and published by Springer. This book was released on 2017-04-05 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of flow-based, microfluidic VLSI. The authors describe and solve in a comprehensive and holistic manner practical challenges such as control synthesis, wash optimization, design for testability, and diagnosis of modern flow-based microfluidic biochips. They introduce practical solutions, based on rigorous optimization and formal models. The technical contributions presented in this book will not only shorten the product development cycle, but also accelerate the adoption and further development of modern flow-based microfluidic biochips, by facilitating the full exploitation of design complexities that are possible with current fabrication techniques.
Book Synopsis Design Automation Methods and Tools for Microfluidics-Based Biochips by : Jun Zeng
Download or read book Design Automation Methods and Tools for Microfluidics-Based Biochips written by Jun Zeng and published by Springer Science & Business Media. This book was released on 2006-11-08 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design Automation Methods and Tools for Microfluidics-Based Biochips deals with all aspects of design automation for microfluidics-based biochips. Experts have contributed chapters on many aspects of biochip design automation. Topics covered include: device modeling; adaptation of bioassays for on-chip implementations; numerical methods and simulation tools; architectural synthesis, scheduling and binding of assay operations; physical design and module placement; fault modeling and testing; and reconfiguration methods.
Book Synopsis Secure and Trustworthy Cyberphysical Microfluidic Biochips by : Jack Tang
Download or read book Secure and Trustworthy Cyberphysical Microfluidic Biochips written by Jack Tang and published by Springer. This book was released on 2019-05-28 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes novel hardware security and microfluidic biochip design methodologies to protect against tampering attacks in cyberphysical microfluidic biochips (CPMBs). It also provides a general overview of this nascent area of research, which will prove to be a vital resource for practitioners in the field.This book shows how hardware-based countermeasures and design innovations can be a simple and effective last line of defense, demonstrating that it is no longer justifiable to ignore security and trust in the design phase of biochips.
Book Synopsis Design Tools and Optimization Methods for Digital Microfluidic Biochips by : Tao Xu
Download or read book Design Tools and Optimization Methods for Digital Microfluidic Biochips written by Tao Xu and published by . This book was released on 2007 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms by : Mohamed Ibrahim
Download or read book Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms written by Mohamed Ibrahim and published by CRC Press. This book was released on 2020-05-31 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: A microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.
Book Synopsis Security Opportunities in Nano Devices and Emerging Technologies by : Mark Tehranipoor
Download or read book Security Opportunities in Nano Devices and Emerging Technologies written by Mark Tehranipoor and published by CRC Press. This book was released on 2017-11-22 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The research community lacks both the capability to explain the effectiveness of existing techniques and the metrics to predict the security properties and vulnerabilities of the next generation of nano-devices and systems. This book provides in-depth viewpoints on security issues and explains how nano devices and their unique properties can address the opportunities and challenges of the security community, manufacturers, system integrators, and end users. This book elevates security as a fundamental design parameter, transforming the way new nano-devices are developed. Part 1 focuses on nano devices and building security primitives. Part 2 focuses on emerging technologies and integrations.
Book Synopsis Droplet and Digital Microfluidics by : Sanket Goel
Download or read book Droplet and Digital Microfluidics written by Sanket Goel and published by Elsevier. This book was released on 2024-03-11 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Droplet and Digital Microfluidics: Ideation to Implementation is a detailed introduction to the dynamics of droplet and digital microfluidics, also featuring coverage of new methods and applications. The explosion of applications of microelectromechanical systems (MEMS) in recent years has driven demand for expertise and innovation in fluid flow in the microchannels they contain. In this book, detailed descriptions of methods for biological and chemical applications of microfluidics are provided, along with supporting foundational knowledge. In addition, the principles of droplet and digital microfluidics are explained, along with their different applications and governing physics. New additions to the technological knowledgebase that enable advances in droplet and digital microfluidics include machine learning and exciting future avenues for research. Provides step-by-step fabrication, testing, and characterization instructions in each chapter to support implementation Includes explanations of applications and methods in biological and chemical settings Describes the path to automation of digital and droplet microfluidic platforms
Book Synopsis Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip by : Sudip Poddar
Download or read book Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip written by Sudip Poddar and published by CRC Press. This book was released on 2022-07-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.
Book Synopsis VLSI 2010 Annual Symposium by : Nikolaos Voros
Download or read book VLSI 2010 Annual Symposium written by Nikolaos Voros and published by Springer Science & Business Media. This book was released on 2011-09-08 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: VLSI 2010 Annual Symposium will present extended versions of the best papers presented in ISVLSI 2010 conference. The areas covered by the papers will include among others: Emerging Trends in VLSI, Nanoelectronics, Molecular, Biological and Quantum Computing. MEMS, VLSI Circuits and Systems, Field-programmable and Reconfigurable Systems, System Level Design, System-on-a-Chip Design, Application-Specific Low Power, VLSI System Design, System Issues in Complexity, Low Power, Heat Dissipation, Power Awareness in VLSI Design, Test and Verification, Mixed-Signal Design and Analysis, Electrical/Packaging Co-Design, Physical Design, Intellectual property creating and sharing.
