Dendritic Cells In Fundamental And Clinical Immunology

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Dendritic Cells in Fundamental and Clinical Immunology

Author : Paola Ricciardi-Castagnoli
Publisher : Springer Science & Business Media
ISBN 13 : 1475799667
Total Pages : 566 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Dendritic Cells in Fundamental and Clinical Immunology by : Paola Ricciardi-Castagnoli

Download or read book Dendritic Cells in Fundamental and Clinical Immunology written by Paola Ricciardi-Castagnoli and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: These proceedings contain selected contributions from the participants to the Fourth International Symposium on Dendritic cells that was held in Venice (Lido) Italy, from Oc tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At this meeting it has been shown that large quantities of DC can be generated from precursors in both mice and humans, and this possibility has enormously encouraged studies aimed to characterize DC physiology and DC-specific genes, and to employ DC therapeutically as adjuvants for im munization. The possibility of generating large numbers of autologous DC that can be used in the manipulation of the immune response against cancer and infectious diseases has tremendously boosted dendritic cell research and the role of DC in a number of medi cal areas has been heatedly discussed.

Dendritic Cells in Fundamental and Clinical Immunology

Author : Eduard W. A. Kamperdijk
Publisher : Springer Science & Business Media
ISBN 13 : 1461529301
Total Pages : 631 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Dendritic Cells in Fundamental and Clinical Immunology by : Eduard W. A. Kamperdijk

Download or read book Dendritic Cells in Fundamental and Clinical Immunology written by Eduard W. A. Kamperdijk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: These Proceedings contain the contributions of the participants of the Second International Symposium on Dendritic Cells that was held from the 1st to 25th of June 1992 in Amsterdam, the Netherlands. The First International Symposium on Dendritic Cells was organized as a Satellite symposium at the occasion of the 30th anniversary of the Japanese Reticuloendothelial Society by Dr. Y. Imai in Yamagata (Japan), in 1990. It was entitled "Dendritic Cells in Lymphoid Tissues," and focused primarily on the Interdigitating Cells (IDC), Epidermal Langerhans cells (LC) and Follicular Dendritic Cells (FDC) , from the point of view of human pathology. However, the concept of Dendritic Cell System, comprising the bone marrow derived IDC and LC but not the FDC, was based on animal experiments and mainly on in vitro experiments on isolated cells. In a report from the Reticuloendothelial Society Committee on Nomenclature in 1982, Tew, Thorbecke and Steinman had already characterized these different types of DC, but the gap between in vivo and in vitro function remained. In Amsterdam, the Symposium focused on the Role of Dendritic Cells in Fundamental and Clinical Immunology. First, recent developments in molecular biology of antigen presentation and cell biological aspects of signal transduction were discussed, in relation to the potential of DC to stimulate lymphocytes and to trigger their in vitro differentiation.

Dendritic Cells in Fundamental and Clinical Immunology

Author : Jacques Banchereau
Publisher : Springer Science & Business Media
ISBN 13 : 1461519713
Total Pages : 493 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Dendritic Cells in Fundamental and Clinical Immunology by : Jacques Banchereau

Download or read book Dendritic Cells in Fundamental and Clinical Immunology written by Jacques Banchereau and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: These Proceedings contain the contributions of the partIcIpants of the Third International Symposium on Dendritic Cells that was held in Annecy, France, from June 19 to June 24, 1994. This symposium represented a follow-up of the first and second international symposia that were held in Japan in 1990 and in the Netherlands in 1992. Dendritic cells are antigen-presenting cells, and are found in all tissues and organs of the body. They can be classified into: (1) interstitial dendritic cells of the heart, kidney, gut, and lung;(2) Langerhans cells in the skin and mucous membranes; (3) interdigitating dendritic cells in the thymic medulla and secondary lymphoid tissue; and (4) blood dendritic cells and lymph dendritic cells (veiled cells). Although dendritic cells in each of these compartments are all CD45+ leukocytes that arise from the bone marrow, they may exhibit differences that relate to maturation state and microenvironment. Dendritic cells are specialized antigen-presenting cells for T lymphocytes: they process and present antigens efficiently in situ, and stimulate responses from naive and memory T cells in the paracortical area of secondary lymphoid organs. Recent evidence also demonstrates their role in induction of tolerance. By contrast, the primary and secondary B-cell follicles contain follicular dendritic cells that trap and retain intact antigen as immune complexes for long periods of time. The origin of follicular dendritic cells is not clear, but most investigators believe that these cells are not leukocytes.

Dendritic Cells in Fundamental and Clinical Immunology

Author : Paola Ricciardi-Castagnoli
Publisher : Springer
ISBN 13 : 9781475799675
Total Pages : 612 pages
Book Rating : 4.7/5 (996 download)

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Book Synopsis Dendritic Cells in Fundamental and Clinical Immunology by : Paola Ricciardi-Castagnoli

Download or read book Dendritic Cells in Fundamental and Clinical Immunology written by Paola Ricciardi-Castagnoli and published by Springer. This book was released on 2014-01-15 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Basic and Clinical Immunology

Author : Andrzej Mackiewicz
Publisher : Springer Science & Business Media
ISBN 13 : 1461506859
Total Pages : 422 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Progress in Basic and Clinical Immunology by : Andrzej Mackiewicz

Download or read book Progress in Basic and Clinical Immunology written by Andrzej Mackiewicz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Basic and Clinical Immunology is a result of the 14th European Immunology Meeting - EFIS 2000, held in Poznan, Poland, on 23-27 September 2000. EFIS 2000 gathered over 1400 immunologists from all over the world. It was an exceptionally memorable meeting for a number of reasons: 1) it was held in the last year of the century and the millennium, thus provoking conclusions of past achievements of immunology and projections for the future; 2) it was held in Poland, a country that is a symbol of struggle for freedom for a large number of scientists originating from the `Eastern Bloc' countries; and 3) EFIS celebrated its 25th anniversary at this occasion. This comprehensive volume contains 62 chapters grouped into 11 sections: T-cells, Immune Receptors, Antigen Presentation/Dendritic Cells, Cytokines, Immunodeficiencies, Autoimmunity, Allergy/Inflammation, Immunotherapy, Vaccines, Tumor Immunology, and Cancer Immunotherapy.

From Basic to Clinical Immunology

Author : Vladimir V. Klimov
Publisher : Springer
ISBN 13 : 3030033236
Total Pages : 377 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis From Basic to Clinical Immunology by : Vladimir V. Klimov

Download or read book From Basic to Clinical Immunology written by Vladimir V. Klimov and published by Springer. This book was released on 2019-03-06 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills a gap at the interface of fundamental and clinical immunology, and allergy. For many years, experts in fundamental immunology and physicians involved in clinical immunology and allergy worked separately – but the fundamental immunologists did not have medical qualifications and the physicians were not involved in the field of fundamental research. Written by a teacher and an expert in both fields, this book combines current knowledge on basic immunology and immunopathology with clinical comments that complete the whole picture. Immunology is a complex science, which requires a simplified approach in order to be taught and understood effectively. This book is based on the authors’ long experience in teaching undergraduate, postgraduate students and interns both basic and clinical immunology. Reviewing a variety of important components related to the immune system, it is clearly and logically structured, and enriched by figures, tables and boxes with important immunology definitions. Each chapter has its own bibliography, and most units include links to electronic quizzes and audio files to accompany readers step by step. This easy-to-follow volume concludes with suggestions for future study. It is a valuable resource for undergraduate and postgraduate students, as well as medical practitioners.

Dendritic Cells

Author : Michael T. Lotze
Publisher : Elsevier
ISBN 13 : 0080491073
Total Pages : 851 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Dendritic Cells by : Michael T. Lotze

Download or read book Dendritic Cells written by Michael T. Lotze and published by Elsevier. This book was released on 2001-08-20 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendritic Cells, Second Edition is the new edition of the extremely successful book published in 1998. With the volume of literature on dendritic cells doubling every year, it is almost impossible to keep up. This book provides the most up-to-date synthesis of the literature, written by the very best authors. It is essential reading for any scientist working in immunology, cell biology, infectious diseases, cancer, transplantation, genetic engineering, or the pharmaceutical/biotechnology industry. An entirely new section on DC biology is included in this edition. Also new to this edition are chapters on: Imaging Interaction of dendritic cells with viruses Dendritic cells and dendrikines, chemokines and the endothelium Molecules expressed in dendritic cells Role of dendritic cells in wound healing and atherosclerosis Delivery of apoptotic bodies Genetic engineering of dendritic cells Imaging Practical aspects of clinical protocol development

Dendritic Cells in Clinics

Author : Morikazu Onji
Publisher : Springer Science & Business Media
ISBN 13 : 4431670114
Total Pages : 196 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Dendritic Cells in Clinics by : Morikazu Onji

Download or read book Dendritic Cells in Clinics written by Morikazu Onji and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Great advances have taken place in basic research and the clinical usefulness of dendritic cells (DCs). It has now been clearly established, for instance, that these cells play a crucial role in immune responses against infectious diseases and cancers. Antigen-presenting DCs are widely distributed in the body and regulate both immunity and immune tolerance. Experimental studies have provided important insights into DCs and how they can be used for treating animal models of various diseases that occur in humans. The role of these cells in pathogenesis and the treatment of human diseases is elaborately set forth in this valuable book. Researchers in the field are optimistic that DCs, already in use for treating patients with cancers, soon can be used therapeutically for patients with chronic infections, autoimmune diseases, and allergic manifestations. This volume provides a working definition of DCs and also explains the phenotypes and functions of DCs so that these can be readily understood not only by clinicians but by immunologists, researchers, and students as well.

Dendritic Cell Protocols

Author : Stephen P. Robinson
Publisher : Springer Science & Business Media
ISBN 13 : 1592591507
Total Pages : 463 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Dendritic Cell Protocols by : Stephen P. Robinson

Download or read book Dendritic Cell Protocols written by Stephen P. Robinson and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendritic Cell Protocols provides chapter and verse for many useful practical approaches to the art of studying dendritic cells. The book gives information on the usual techniques for derivation of human dendritic cells from precursor stem cells, such as monocytes. In addition it provides data on the difficult tasks of isolating dendritic cells directly from different tissues; whether dendritic cells from precursor cells or from tissues of mouse or human are required, this book contributes practical information. The last section of the book is devoted to functional aspects of dendritic cells ranging from inf- mation relevant to cell migration to antigen uptake and T cell stimulation. But what is a dendritic cell? The explosion of studies on this cell type over the last few years is breathtaking. We now have so-called “myeloid” and “plas- cytoid” dendritic cells; are they of separate lineages or are they related? There are claims that dendritic cells can be derived from B cells and from granulocytes, as well as from “monocytes. ” Lymphocytes can be switched on or off by dendritic cells. Dendritic cells can preferentially cause Th1 or Th2 responses or some may stimulate B cells directly. When there is so much scope for exploring these new developments, it is particularly important that the data that are established and the practical basis for this work are clearly available, a task that this book fulfils.

Fundamental Immunology

Author : William E. Paul
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451117833
Total Pages : 1313 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Fundamental Immunology by : William E. Paul

Download or read book Fundamental Immunology written by William E. Paul and published by Lippincott Williams & Wilkins. This book was released on 2012-12-10 with total page 1313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental Immunology Seventh Edition This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed. Look inside and discover... * Fully revised and updated content reflects the latest advances in the field. * Current insights enhance readers' understanding of immune system function * Unique approach bridges the gap between basic immunology and the disease process. * Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. * Abundant illustrations and tables deliver essential information at a glance. PLUS... A convenient companion website features the fully searchable text with all references linked to PubMed. Pick up your copy today!

Essential Clinical Immunology

Author : John B. Zabriskie
Publisher : Cambridge University Press
ISBN 13 : 0521516811
Total Pages : 373 pages
Book Rating : 4.5/5 (215 download)

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Book Synopsis Essential Clinical Immunology by : John B. Zabriskie

Download or read book Essential Clinical Immunology written by John B. Zabriskie and published by Cambridge University Press. This book was released on 2009-01-12 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book begins with basic concepts of immunology and then details the immunological aspects of various disease states involving major organs of the body. Designed as an introduction for practitioners and residents, this book explores how we can better understand disease and its treatment through clinical immunology.

Basic and Clinical Immunology

Author : Mark Peakman
Publisher :
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Basic and Clinical Immunology by : Mark Peakman

Download or read book Basic and Clinical Immunology written by Mark Peakman and published by . This book was released on 2009 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this text is on the human immunology required by students to understand and treat common immunological diseases - animal research is included only where essential for an understanding of the subject.

The Biology of Dendritic Cells and HIV Infection

Author : Sandra Gessani
Publisher : Springer Science & Business Media
ISBN 13 : 0387337857
Total Pages : 562 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis The Biology of Dendritic Cells and HIV Infection by : Sandra Gessani

Download or read book The Biology of Dendritic Cells and HIV Infection written by Sandra Gessani and published by Springer Science & Business Media. This book was released on 2007-03-09 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlying the pathogenesis of viral diseases. This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It is the only comprehensive volume on pathogenesis and immunity of Dendritic Cells that also focuses on HIV.

An Antigen Depository of the Immune System: Follicular Dendritic Cells

Author : Marie H. Kosco-Vilbois
Publisher : Springer Science & Business Media
ISBN 13 : 3642796036
Total Pages : 215 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis An Antigen Depository of the Immune System: Follicular Dendritic Cells by : Marie H. Kosco-Vilbois

Download or read book An Antigen Depository of the Immune System: Follicular Dendritic Cells written by Marie H. Kosco-Vilbois and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Follicular dendritic cells (FOe) are unique among cells of the immune system. While their morphological characteristics re sulted in their inclusion as a 'dendritic cell type', tt1ey differ quite significantly from the other members of the dendritic cell family. In contrast to T-cell-associated dendritic cells or the Langerhans cells found in the skin, FOe reside in highly organized B cell follicles within secondary lymphoid tissues. This site of resi dence provided a nomenclature committee in 1982 with the second descriptive factor for the derivation of their name. The cardinal feature of FOe is to trap and retain antigen on the surface of their dendritic processes for extended amounts of time and it is this feature that provides the conceptual compo nent for the title of this book. In response to an antigenic challenge, primary B cell follicles undergo dynamic events, giving rise to germinal centers which are associated with activation, expansion, and differentiation processes of B cells. The interactions of B cells with Foe and T cells in the germinal centers are essential for generating the complete repertoire of antibody isotypes obtained during an antibody response. In addition, stimuli either initiated or main tained during the germinal center reponse leads to production of high affinity antibodies through the processes of somatic muta tion and clonal selection. In this context, FOe act as a pivotal source of antigen. They accumulate foreign proteins (e. g.

Harnessing the Participation of Dendritic Cells in Immunity and Tolerance

Author : Silvia Beatriz Boscardin
Publisher : Frontiers Media SA
ISBN 13 : 2889662012
Total Pages : 511 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Harnessing the Participation of Dendritic Cells in Immunity and Tolerance by : Silvia Beatriz Boscardin

Download or read book Harnessing the Participation of Dendritic Cells in Immunity and Tolerance written by Silvia Beatriz Boscardin and published by Frontiers Media SA. This book was released on 2020-12-10 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Dendritic Cell Control of Immune Responses

Author : Penelope Anne Morel
Publisher : Frontiers Media SA
ISBN 13 : 2889198685
Total Pages : 123 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Dendritic Cell Control of Immune Responses by : Penelope Anne Morel

Download or read book Dendritic Cell Control of Immune Responses written by Penelope Anne Morel and published by Frontiers Media SA. This book was released on 2016-07-27 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendritic cells (DC) are among the first cells to encounter pathogens and damage in peripheral tissues and, upon activation, DC migrate to lymph nodes where they activate and educate T cells to initiate and shape the immune response. DC present pathogen-derived antigen to T cells and drive T cell differentiation into particular effector cells through the expression and secretion of co-stimulatory molecules and cytokines respectively. The study of DC biology has included the identification of multiple DC subsets in tissues and lymphoid organs, the differentiation and plasticity of DC subsets, the functional consequences of DC interaction with pathogen, control of DC migratory properties and the impact of DC on T cell activation and differentiation. In recent years sophisticated systems biology approaches have been developed to deepen our understanding of DC function. These studies have identified differences between DC subsets located in various tissues and critical factors that drive the outcome of the interaction between DC and T cells. DC are currently being used in in various clinical therapeutic settings, including as vaccines for cancer and autoimmune disease. A clear understanding of DC factors that contribute to specific immune responses is vital to the success of DC based therapies. This research topic will give a comprehensive overview of current issues in DC biology and provides an update on the clinical uses of DC in the therapy of autoimmunity and cancer.

Clinical Immunology E-Book

Author : Robert R. Rich
Publisher : Elsevier Health Sciences
ISBN 13 : 0702081663
Total Pages : 1308 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Clinical Immunology E-Book by : Robert R. Rich

Download or read book Clinical Immunology E-Book written by Robert R. Rich and published by Elsevier Health Sciences. This book was released on 2022-08-23 with total page 1308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering unique, comprehensive coverage of both basic science and clinical scenarios, Clinical Immunology: Principles and Practice, 6th Edition, brings you up to date with every aspect of this fast-changing field. It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; it also includes complete coverage of common and uncommon immunologic disorders. Updated with all the latest immunologic research and clinical implications, including breakthrough immunotherapies and molecular-based treatment protocols, this fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume. Includes extensive revisions that reflect rapidly expanding research and clinical advances, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine. Contains new chapters on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically focused chapter on asthma. Provides new genetics content focused on data applications. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and in the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Features a user-friendly format with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles. Summarizes promising research and development anticipated over the next 5–10 years with "On the Horizon" boxes and discussions of translational research.