Cytokines In The Treatment Of Infectious Diseases

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Cytokines in the Treatment of Infectious Diseases

Author : B.J. Kullberg
Publisher : Springer Science & Business Media
ISBN 13 : 9401102333
Total Pages : 118 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Cytokines in the Treatment of Infectious Diseases by : B.J. Kullberg

Download or read book Cytokines in the Treatment of Infectious Diseases written by B.J. Kullberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Only recently a new range of agents has become available that are capable of stimulating and regulating host defense systems against microorganisms. Interleukins, interferons and haematopoietic growth factors are now being produced by the biotechnology industry and are being evaluated for clinical use in this area. Cytokines in the Treatment of Infectious Diseases provides a unique, up-to-date survey of this research area. The use of cytokines in a series of (groups of) infectious diseases is discussed in twelve succinct chapters, from model to clinical study, written by twenty-five expert authors from the world's key institutes in this area. The book is aimed at microbiologists, immunologists, molecular biologists, cell biologists and other scientific disciplines in the field of biotherapy. It is required reading for physicians dealing with infectious diseases who wish to keep up to date with the developments in this field.

Cytokines and Chemokines in Infectious Diseases Handbook

Author : Malak Kotb
Publisher : Springer Science & Business Media
ISBN 13 : 1592593097
Total Pages : 425 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Cytokines and Chemokines in Infectious Diseases Handbook by : Malak Kotb

Download or read book Cytokines and Chemokines in Infectious Diseases Handbook written by Malak Kotb and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of what is known about the role of cytokines and chemokines in a variety of human infectious diseases, including gram-negative and -positive infections, listeriosis, mycobacterial infections, lyme arthritis, pneumonia, fungal infections, HIV, leishmaniasis, and sepsis. The authors demonstrate the different cytokine and chemokine production profiles in response to a wide variety of pathogens and the importance of host genetic factors in determining the type and magnitude of responses to a given microorganism. They also critically evaluate the use of cytokines and anticytokines in the treatment of infectious diseases and show how knowledge of cytokine pleiotropic effects, redundancy, and the complexity of the cytokine network has led to better design and better outcomes in cytokine-based therapies for specific infections.

Significance of Cytokines in the Treatment of Infectious Diseases

Author : Uwe Ullmann
Publisher : Vch Pub
ISBN 13 : 9781560813750
Total Pages : 175 pages
Book Rating : 4.8/5 (137 download)

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Book Synopsis Significance of Cytokines in the Treatment of Infectious Diseases by : Uwe Ullmann

Download or read book Significance of Cytokines in the Treatment of Infectious Diseases written by Uwe Ullmann and published by Vch Pub. This book was released on 1993-11-01 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Applications of Cytokines

Author : Joost J. Oppenheim
Publisher : Oxford University Press, USA
ISBN 13 : 9780195071290
Total Pages : 406 pages
Book Rating : 4.0/5 (712 download)

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Book Synopsis Clinical Applications of Cytokines by : Joost J. Oppenheim

Download or read book Clinical Applications of Cytokines written by Joost J. Oppenheim and published by Oxford University Press, USA. This book was released on 1993 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The driving force for research on cytokines has always been their clinical promise. Their biological properties suggested a key role in hematopoiesis, immunity, tumor genesis, hemostasis, vascularization, repair of connective tissues and integration of the immune system with the neuroendocrine system. Animal studies have shown that cytokines could be used as effective biotherapeutics with easily manageable and reversible toxicities. Clinical trials have confirmed these findings, culminating in the licensing of a number of the cytokines such as interferon alpha, interferon gamma, interleukin 2, erythropoietin, granulocyte colony stimulating factor, and granulocyte-macrophage colony stimulating factor. Many other cytokines are in clinical trials. This is the first comprehensive volume on the cytokines written primarily from a medical perspective. After presenting background information about the structure, production, assays and systemic effects of cytokines and their receptors, it is organized around diseases and organ systems. Infectious diseases, autoimmunity, immunodeficiency states, defective hematopoiesis, allergies, injury repair, cancer, vascular and skin diseases, and neurological disorders are all covered. This work reviews the role that cytokines play in the pathogenesis, diagnosis and therapy of each disease. The authors assess both the current state of the art and the potential for future applications.

Immunotherapy of Infections

Author : K. Noel Masihi
Publisher : CRC Press
ISBN 13 : 9780824792091
Total Pages : 542 pages
Book Rating : 4.7/5 (92 download)

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Book Synopsis Immunotherapy of Infections by : K. Noel Masihi

Download or read book Immunotherapy of Infections written by K. Noel Masihi and published by CRC Press. This book was released on 1994-07-15 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the International Symposium on Immunotherapy of Infections held recently at the Robert Koch Institute, Berlin, Germany, this work discusses cytokines as well as synthetic and natural immunomodulators and their applications in the immunotherapy of bacterial, viral, parasitic and fungal infections.;The contributors describe innovative treatment concepts that act as adjuncts to established therapies for the control of both existing and newly emerging infectious diseases.

Cytokines in Pulmonary Disease

Author : Thomas Martin
Publisher : CRC Press
ISBN 13 : 9780824719319
Total Pages : 624 pages
Book Rating : 4.7/5 (193 download)

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Book Synopsis Cytokines in Pulmonary Disease by : Thomas Martin

Download or read book Cytokines in Pulmonary Disease written by Thomas Martin and published by CRC Press. This book was released on 2000-01-18 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the role of the cytokine network in promoting immunity, this superb interdisciplinary collection intensively investigates the behavior of inflammatory mediators in the pathogenesis and resolution of pathogen-specific pulmonary infections-highlighting recent basic findings and discussing the latest results of clinical trials. Defines the vital role that cytokines play in host defense and the pathophysiology of infections associated with pulmonary disease, emphasizing the potential of immunomodulators and gene therapy in treatment. Cytokines in Pulmonary Disease provides state-of-the-art knowledge of the field of cytokines and pulmonary diseases in a single, authoritative source reviews the roles of cytokines in pathogen-specific infections, including tuberculosis, HIV-related infections, fungal pneumonias, cystic fibrosis, and other disorders assesses the rationale and efficacy of new approaches in both the prevention and treatment of pulmonary infectious disease examines the clinical applications and impact of cytokines in pulmonary disease and more. Written by leading international authorities in their respective fields, Cytokines in Pulmonary Disease will find a place on the bookshelves of specialists in pulmonary and critical care medicine, infectious diseases, surgery, immunology, microbiology, cell and molecular biology, and medical school and graduate students in these disciplines.

Cytokine Therapeutics in Infectious Diseases

Author : Steven Matthew Holland
Publisher :
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cytokine Therapeutics in Infectious Diseases by : Steven Matthew Holland

Download or read book Cytokine Therapeutics in Infectious Diseases written by Steven Matthew Holland and published by . This book was released on 2001 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytokine Therapeutics in Infectious Diseases provides a comprehensive analysis of the role cytokines fulfill in fighting infectious diseases. Structured to disclose clinical discoveries with clarity and accessibility, the information on therapeutic cytokines is linked to specific diseases. The book closes with a discussion about future directions for research, applications, and studies.

Treating Infectious Diseases in a Microbial World

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309180686
Total Pages : 102 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Treating Infectious Diseases in a Microbial World by : National Research Council

Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

The Cytokines of the Immune System

Author : Zlatko Dembic
Publisher : Academic Press
ISBN 13 : 0124200109
Total Pages : 323 pages
Book Rating : 4.1/5 (242 download)

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Book Synopsis The Cytokines of the Immune System by : Zlatko Dembic

Download or read book The Cytokines of the Immune System written by Zlatko Dembic and published by Academic Press. This book was released on 2015-05-23 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clinical research Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials Offers a textbook-style view on the immune system with the immunologic role of each cytokine

T-Cell Subsets and Cytokines Interplay in Infectious Diseases

Author : Mustafa A.S.
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805561229
Total Pages : 235 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis T-Cell Subsets and Cytokines Interplay in Infectious Diseases by : Mustafa A.S.

Download or read book T-Cell Subsets and Cytokines Interplay in Infectious Diseases written by Mustafa A.S. and published by Karger Medical and Scientific Publishers. This book was released on 1996 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting a wealth of new data on the interaction among T-cell subsets and cytokines, this book offers a fresh perspective on infectious diseases. It provides useful insights into the nature and treatment of helminthic and mycobacterial infections, with special emphasis on leprosy, leishmaniasis, malaria and trypanosomiasis. The outcome of the host response to infectious agent is seen as depending upon the T-cell subsets activated and the cytokines produced by them and other cells, such as macrophages, B cells and basophils. Experts contributions shed new light on how TH0 cells are preferentially activated and differentiated into TH1 or TH2 subsets; TH1 and TH2 cells and their cytokines induce both protective immune responses and adverse immune reactions to infectious agents; cytokines modulate the response of infectious diseases to chemotherapy; and cytokines, their receptors and antagonist, and anti-cytokine antibodies can be used in therapy. Those working in the fields of immunology, parasitology, microbiology and vaccine development particularly if they are interested in tropical diseases, will find the volume an invaluable source of information.

Cytokines: Roles and Therapeutic Implications

Author : Erik Krueger
Publisher :
ISBN 13 : 9781536190366
Total Pages : pages
Book Rating : 4.1/5 (93 download)

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Book Synopsis Cytokines: Roles and Therapeutic Implications by : Erik Krueger

Download or read book Cytokines: Roles and Therapeutic Implications written by Erik Krueger and published by . This book was released on 2021-02-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytokines are commonly referred to as the "language of intercellular interaction" since they send signals and commands to the cells to perform certain functions. In this compilation, the authors discuss how cytokines have demonstrated different patterns of production and interaction with other cytokines; therefore, cytokines can be considered as diagnostical markers and possible targets for therapeutic measures.The authors illuminate the role of cytokines in different physiological circumstances affecting the onset, development and resolution of inflammation associated with inflammatory bowel disease.The administration of cytokines as therapeutics has proven potential in the treatment of cancer and infectious and non-infectious disease. The authors discuss cytokine profiles and their signaling in the autoimmune disease Guillain-Barre syndrome, and the potential of using this specific information for developing new therapeutic strategies.The concluding study focuses on malignant breast cancer, the most common cancer in women worldwide. In recent decades, many advances have occurred in understanding the role of cytokines in this cancer, with several studies on new diagnostic and prognostic markers and their applications as a target in treatment.

Cytokines in Autoimmunity

Author : Fionula M. Brennan
Publisher : Landes Bioscience
ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Cytokines in Autoimmunity by : Fionula M. Brennan

Download or read book Cytokines in Autoimmunity written by Fionula M. Brennan and published by Landes Bioscience. This book was released on 1996 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of the field of cytokines in autoimmunity written by 22 researchers suggesting diverse applications, and building on the successes of recent rheumatoid arthritis clinical trials. The contributors present and review findings on arthritis, diabetes, multiple sclerosis, thyroid disease, Sjogren's syndrome, Lupus, scleroderma, and psoriasis. The final sections concentrate on laboratory and clinical concerns working with "knockout" mice, transgenic mice, and cytokine therapy. Distributed by Chapman and Hall. CiP shows the title as Role of cytokines..... Annotation copyright by Book News, Inc., Portland, OR

Cytokines in Severe Sepsis and Septic Shock

Author : H. Redl
Publisher : Springer
ISBN 13 : 3034887558
Total Pages : 377 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Cytokines in Severe Sepsis and Septic Shock by : H. Redl

Download or read book Cytokines in Severe Sepsis and Septic Shock written by H. Redl and published by Springer. This book was released on 2013-03-11 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word "sepsis" derives from the Greek meaning decay or rottenness. Tradition ally this term has been used to describe the process of infection accompanied by the host's systemic inflammatory response. Based on that understanding, previous clin ical studies have been designed to include only patients with positive blood cultures [1, 2]. However, the frequent occurrence of a septic response without the demon stration of microorganisms in the circulation has led to a new definition and under standing of sepsis, mainly as the systemic response of the host to an often unde tectable microbiological or non-microbiological process [3]. The general consensus is that cytokines are central to the inflammatory response, particularly in sepsis. It is now known that not only Gram-negative but also Gram positive, viral, and fungal infections initiate the complex cascades of cytokine release. Probably the most important aspect of bacterial action is the release of toxic bacterial products. In particular endotoxin from Gram-negative bacteria (see chap ter by Schade) and super antigens (see chapter by Neumann and Holzmann), as well as pore-forming toxins [4] from Gram-positive bacteria, induce cytokine formation. The importance of this cytokine release is evident from both diagnostic and thera peutic (mostly experimental) studies, and the action of cytokines may be the key to our understanding of the pathophysiology of the sepsis syndrome.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Cytokines

Author : Masoud H. Manjili
Publisher : Nova Science Publishers
ISBN 13 : 9781621009757
Total Pages : 286 pages
Book Rating : 4.0/5 (97 download)

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Book Synopsis Cytokines by : Masoud H. Manjili

Download or read book Cytokines written by Masoud H. Manjili and published by Nova Science Publishers. This book was released on 2012-06-01 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells of the immune system communicate with each other, and respond to abnormal conditions by releasing soluble proteins, named cytokines. Abnormal or dangerous conditions include infection, trauma and injury, neurological disorders, and cancer. The balance between pro- and anti-inflammatory cytokines can comfort or exacerbate the symptoms in these diseases. This book focuses on counter-regulatory and the role of cytokines in different diseases. The goal is to understand contribution of cytokines in the progression of the disease as well as therapeutic potential of cytokines in the treatment of the disease by understanding cytokine counter-regulation.

Cytokines in the Treatment of Hematopoietic Failure

Author : Arnold Ganser
Publisher : CRC Press
ISBN 13 : 9780824701932
Total Pages : 416 pages
Book Rating : 4.7/5 (19 download)

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Book Synopsis Cytokines in the Treatment of Hematopoietic Failure by : Arnold Ganser

Download or read book Cytokines in the Treatment of Hematopoietic Failure written by Arnold Ganser and published by CRC Press. This book was released on 1998-09-03 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world experts in the field, this book presents up-to-date, in-depth coverage of hematopoietic growth factors and related cytokines that are currently being developed or used for managing congenital and acquired forms of chronic cytopenias. Summarizes important clinical trial data in a convenient tabulated format and provides fundamental knowledge on hematopoiesis physiology and regulation! Facilitating rational decision making and cost-effective treatment strategies, this clinically and disease-oriented work describes as well as assesses the benefits and limitations of hematopoietic growth factor and cytokine use in graft failure peripheral-blood progenitor cell transplantation chemotherapy- and radiotherapy-induced cytopenias in patients with solid tumors and hematological malignancies, including leukemias and myelodysplastic syndromes cytopenic states related to infectious conditions such as AIDS ex vivo expansion of hematopoietic progenitor cells post-operative procedures for bone marrow transplantation renal failure the neonate transfusion medicine and more! Supplemented with literature citations and drawings, Cytokines in the Treatment of Hematopoietic Failure is an essential resource for hematologists, oncologists, internists, radiotherapists, pediatricians, neonatologists, infectious disease specialists, nephrologists, immunologists, transfusion medicine specialists, researchers in pharmaceutical companies, and graduate and medical school students in these disciplines.

Biologic Response Modifiers in Infectious Diseases, An Issue of Infectious Disease Clinics - E-Book

Author : Nancy M. Khardori
Publisher : Elsevier Health Sciences
ISBN 13 : 1455712078
Total Pages : 222 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Biologic Response Modifiers in Infectious Diseases, An Issue of Infectious Disease Clinics - E-Book by : Nancy M. Khardori

Download or read book Biologic Response Modifiers in Infectious Diseases, An Issue of Infectious Disease Clinics - E-Book written by Nancy M. Khardori and published by Elsevier Health Sciences. This book was released on 2011-11-30 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologic response modifiers (BRMs) are substances that stimulate the body's response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts for use in treating infections and other diseases. This issue reviews the use of BRMs to treat infectious diseases as well as the infectious complications of BRMs used to treat non-infectious diseases. Articles on vaccines, antibodies, interferon, and other substances are included.