Current State Of Alzheimers Disease Research And Therapeutics

Download Current State Of Alzheimers Disease Research And Therapeutics full books in PDF, epub, and Kindle. Read online Current State Of Alzheimers Disease Research And Therapeutics ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Current State of Alzheimer's Disease Research and Therapeutics

Author :
Publisher : Academic Press
ISBN 13 : 0123948452
Total Pages : 399 pages
Book Rating : 4.1/5 (239 download)

DOWNLOAD NOW!

Book Synopsis Current State of Alzheimer's Disease Research and Therapeutics by :

Download or read book Current State of Alzheimer's Disease Research and Therapeutics written by and published by Academic Press. This book was released on 2012-07-24 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease, and Identification of protein kinase C for the treatment of dementias. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Explores the current state of Alzheimer's disease research and therapeutics Chapters cover a variety of topics such as the role heat shock proteins play in the Alzheimer's theater, gamma-secretase as a target for Alzheimer's disease, and identification of protein kinase C for the treatment of dementias With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike

Alzheimer's Disease Drug Development

Author : Jeffrey Cummings
Publisher : Cambridge University Press
ISBN 13 : 1108838669
Total Pages : 575 pages
Book Rating : 4.1/5 (88 download)

DOWNLOAD NOW!

Book Synopsis Alzheimer's Disease Drug Development by : Jeffrey Cummings

Download or read book Alzheimer's Disease Drug Development written by Jeffrey Cummings and published by Cambridge University Press. This book was released on 2022-03-31 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.

Current State of Alzheimer's Disease Research and Therapeutics

Author : Elias K. Michaelis
Publisher : Academic Press
ISBN 13 : 0123948169
Total Pages : 400 pages
Book Rating : 4.1/5 (239 download)

DOWNLOAD NOW!

Book Synopsis Current State of Alzheimer's Disease Research and Therapeutics by : Elias K. Michaelis

Download or read book Current State of Alzheimer's Disease Research and Therapeutics written by Elias K. Michaelis and published by Academic Press. This book was released on 2012-08-02 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Providing a cross-section of current research, treatments and potential clinical developments, this volume of Advances in Pharmacology is an essential resource for biologists, pharmacologists and those engaged with Alzheimer's research."--P. [4] of cover.

Alzheimer's Disease

Author : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Retirement and Aging
Publisher :
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!

Book Synopsis Alzheimer's Disease by : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Retirement and Aging

Download or read book Alzheimer's Disease written by United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Retirement and Aging and published by . This book was released on 2007 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Frontiers in Clinical Drug Research – Dementia: Volume 2

Author : José Juan Antonio Ibarra Arias
Publisher : Bentham Science Publishers
ISBN 13 : 9815039482
Total Pages : 277 pages
Book Rating : 4.8/5 (15 download)

DOWNLOAD NOW!

Book Synopsis Frontiers in Clinical Drug Research – Dementia: Volume 2 by : José Juan Antonio Ibarra Arias

Download or read book Frontiers in Clinical Drug Research – Dementia: Volume 2 written by José Juan Antonio Ibarra Arias and published by Bentham Science Publishers. This book was released on 2021-11-09 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among neurodegenerative diseases, those that lead to a state of dementia are the aim of several investigations. Dementia is a chronic disease the prevalence of which is increasing worldwide. The number of dementia patients in the world is approximately 50 million, and it is estimated that the number of patients will reach 131.5 million by 2050. This increase will be accompanied by a significant increase in medical expenditures and other expenses, especially for elderly patients. Therefore, the maintenance cost of dementia in the future is expected to be quite high. For this reason, several investigations aim, firstly, to describe the key mechanisms involved in the origin of dementia and, secondly, to establish preventive and therapeutic strategies in order to understand and mitigate this debilitating pathology. This volume of Frontiers in Clinical Drug Research - Dementia explores the current comorbidities that cause cognitive impairment and the current management alternatives for clinical cases of dementia. The reviews contributed in these volume will provide readers with a current perspective on the subject. The topics covered in this volume include: - Comorbidities inducing mild cognitive impairment - an evaluation of the risk caused by some pathological conditions - Tau-targeted therapy in Alzheimer's disease - history and current state - Emerging nanotherapeutic strategies in Alzheimer's disease - Implication of dehydroepiandrosterone on dementia related to oxidative stress - Polyphenol compounds as potential therapeutic agents in Alzheimer’s disease The volume is a timely update on dementia treatment for clinical physicians, neurologists, gerontologists, pharmaceutical and medicinal chemistry researchers, and physiologists.

The End of Alzheimer’s

Author : Thomas J. Lewis
Publisher : Academic Press
ISBN 13 : 0128121130
Total Pages : 484 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis The End of Alzheimer’s by : Thomas J. Lewis

Download or read book The End of Alzheimer’s written by Thomas J. Lewis and published by Academic Press. This book was released on 2017-05-12 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The End of Alzheimer’s: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer’s outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of Alzheimer’s disease that occur outside the brain. This book uniquely provides step-by-step, peer-reviewed evidence that the current research model may be misguided and that a new and emerging model is more accurate. It carefully outlines the molecular research in Alzheimer’s outside the brain and argues that a more thorough, whole-body diagnosis will provide better answers about its causes and lead to new treatments. It is beneficial to researchers who need to be apprised of the emerging science on the causes of Alzheimer’s, and will hopefully redirect many into new avenues of cellular research and discovery. Comprehensive literature-based summary of the current state of molecular Alzheimer’s disease research Details the shortcomings of the prevailing model and therapeutics in development Reviews blood-based biomarkers for Alzheimer’s and their link to amyloid- and Tau-independent causes outside the brain Describes the tissues outside the brain impacted by Alzheimer’s and the underlying molecular causes Explains the whole-body risks associated with Alzheimer’s, along with concomitant measures to slow or prevent the disease Provides a protocol to properly research, evaluate, measure, diagnose, and potentially treat Alzheimer’s patients

Alzheimer's Disease

Author : Renee D. Wegrzyn
Publisher : CRC Press
ISBN 13 : 1439827087
Total Pages : 308 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!

Book Synopsis Alzheimer's Disease by : Renee D. Wegrzyn

Download or read book Alzheimer's Disease written by Renee D. Wegrzyn and published by CRC Press. This book was released on 2012-04-26 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a tremendous amount of effort has been focused on better understanding the fundamentals of Alzheimer’s disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. Alzheimer’s Disease: Targets for New Clinical, Diagnostic, and Therapeutic Strategies provides a detailed synopsis of the current state of the art of diagnostics and therapeutics and identifies emerging technologies and molecules that show promise in the management and treatment of AD. With contributions from experts drawn from academia, clinical practice, and the biotechnology and pharmaceutical industries, the book explores: The basis of AD and the role of Aβ oligomers in development of disease Existing and emerging in vitro biomarker-based methodologies for the diagnosis of AD, focusing on genetic, biochemical, and conformational strategies In vivo imaging diagnostic approaches Evolving diagnostic criteria, health regulatory guidelines, biomarkers in clinical trials, and available and emerging therapies Recent progress in small-molecule disease-modifier drug discovery efforts for AD, specifically in the areas of Aβ, tau, and emerging neuroprotective/neurorepair approaches How a case study of AD raises issues regarding clinical and pathologic criteria, risk factors, and the amyloid hypothesis The molecular conformational factors that govern the pathogenicity of aggregating proteins, and how these factors could represent new targets for disease-modifying therapies The latest epidemiological, pathological, biochemical, and behavioral studies that may shed some light on the risk of developing AD and similar dementias after traumatic brain injury Examining current hypotheses and suggesting possible new approaches to therapeutic clinical applications, this volume paves the way for a robust pipeline of therapeutics to combat not only AD, but a whole host of other neurodegenerative diseases.

Pharmacological Mechanisms in Alzheimer's Therapeutics

Author : A. Claudio Cuello
Publisher : Springer Science & Business Media
ISBN 13 : 0387715223
Total Pages : 337 pages
Book Rating : 4.3/5 (877 download)

DOWNLOAD NOW!

Book Synopsis Pharmacological Mechanisms in Alzheimer's Therapeutics by : A. Claudio Cuello

Download or read book Pharmacological Mechanisms in Alzheimer's Therapeutics written by A. Claudio Cuello and published by Springer Science & Business Media. This book was released on 2007-12-22 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for effective therapy to treat Alzheimer’s disease is greater than ever, but there is still no drug therapy that can stop or reverse the progression of the disease. There is, however, a great deal of anticipation over the imminent development of effective therapies as a result of the identification of promising targets for drug development. This book investigates these targets and examines ongoing strategies to develop effective therapies for this devastating neurodegenerative condition.

Drug Design and Discovery in Alzheimer’s Disease

Author : Atta-ur Rahman
Publisher : Elsevier
ISBN 13 : 0128039604
Total Pages : 785 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Drug Design and Discovery in Alzheimer’s Disease by : Atta-ur Rahman

Download or read book Drug Design and Discovery in Alzheimer’s Disease written by Atta-ur Rahman and published by Elsevier. This book was released on 2015-06-27 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Design and Discovery in Alzheimer’s Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery. Beginning with an overview of AD pharmacotherapy and existing blockbuster drugs, the reviews cover the potential of both natural and synthetic small molecules; the role of cholinesterases in the on-set and progression of AD and their inhibition; the role of beta-site APP clearing enzyme-1 (BACE-1) in the production of ß-amyloid proteins, one of the key reasons of the progression of AD; and other targets identified for AD drug discovery. Edited and written by leading experts in Alzheimer’s disease (AD) and other neurodegenerative disease drug development Describes existing drugs for AD and current molecular understanding of the condition Reviews recent advances in the field, including coverage of cholinesterases, BACE-1, and other drug development targets

Biomarkers for Alzheimer's Disease Drug Development

Author : Robert Perneczky
Publisher : Springer Nature
ISBN 13 : 1071637746
Total Pages : 345 pages
Book Rating : 4.0/5 (716 download)

DOWNLOAD NOW!

Book Synopsis Biomarkers for Alzheimer's Disease Drug Development by : Robert Perneczky

Download or read book Biomarkers for Alzheimer's Disease Drug Development written by Robert Perneczky and published by Springer Nature. This book was released on 2024 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zusammenfassung: This fully updated volume provides an up-to-date and comprehensive overview of the current state of technologies helping to accelerate Alzheimer's disease drug development. Addressing the latest advances in preclinical and clinical research, including new insights into the molecular mechanisms and emerging therapeutic strategies, the book continues by exploring digital biomarkers and advanced neuroimaging analysis which will transform how clinical trials in the Alzheimer's disease field are performed. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice that leads to greater success in the lab or clinic. Authoritative and practical, Biomarkers for Alzheimer's Disease Drug Development, Second Edition seeks to inspire and inform future efforts to develop effective treatments for this devastating disease

Alzheimer's Disease: Research and Therapeutics

Author : Joshua Barnard
Publisher :
ISBN 13 : 9781632414182
Total Pages : 0 pages
Book Rating : 4.4/5 (141 download)

DOWNLOAD NOW!

Book Synopsis Alzheimer's Disease: Research and Therapeutics by : Joshua Barnard

Download or read book Alzheimer's Disease: Research and Therapeutics written by Joshua Barnard and published by . This book was released on 2016-07-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer is a neurodegenerative disease that worsens over time. It is a form of dementia that starts slowly but ultimately leads to behavioral issues, disorientation, mood swings, problems with language and loss of motivation. Old age, genetic problems, inadequate synthesis of neurotransmitter acetylcholine, extracellular amyloid beta deposits are considered as common causes of this disease. Diagnostic techniques that are used frequently include mini-mental state examination, blood tests, magnetic resonance imaging and positron emission tomography. The causes, diagnosis, prevention, treatment and management technique related to alzheimer's disease have been thoroughly discussed in this book. The topics covered herein will offer new insights in this area of study. This book aims to shed light on some of the unexplored aspects related to this disease and the recent researches in this field. It attempts to assist those with a goal of delving into the research of alzheimer's disease.

Global Clinical Trials for Alzheimer's Disease

Author : Menghis Bairu
Publisher : Academic Press
ISBN 13 : 0124115306
Total Pages : 428 pages
Book Rating : 4.1/5 (241 download)

DOWNLOAD NOW!

Book Synopsis Global Clinical Trials for Alzheimer's Disease by : Menghis Bairu

Download or read book Global Clinical Trials for Alzheimer's Disease written by Menghis Bairu and published by Academic Press. This book was released on 2013-08-28 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global Clinical Trials for Alzheimer’s Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer’s disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the challenges that are present during the planning and execution of global clinical trials for Alzheimer’s disease. Written by leading experts with hands-on experience in designing and running global Alzheimer’s disease and other neurodegenerative diseases clinical trials A step-by-step guide that provides critical information on the design, conduct and standardization necessary to effectively execute clinical trials and accelerate drug development in this area Includes practical examples, ethical considerations, lessons learned and other valuable tools to aid the planning and implementation of Alzheimer’s disease global clinical trials in emerging markets and developing countries

Recent Advances in Alzheimer Research

Author : Ahmad Salehi
Publisher : Bentham Science Publishers
ISBN 13 : 1681081385
Total Pages : 322 pages
Book Rating : 4.6/5 (81 download)

DOWNLOAD NOW!

Book Synopsis Recent Advances in Alzheimer Research by : Ahmad Salehi

Download or read book Recent Advances in Alzheimer Research written by Ahmad Salehi and published by Bentham Science Publishers. This book was released on 2015-11-11 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Alzheimer Disease Research is a book series focusing on contemporary research on Alzheimer’s disease epidemiology, pathophysiology, diagnosis and therapy. The series features reviews by experts in neuroscience and aims to provide current information in the field to both researchers and clinicians. Down syndrome is a chromosomal disorder affecting more than 5.8 million individuals worldwide. Down syndrome can be viewed as a complex multi-system disorder as it manifests into significant physical, psychological, and cognitive abnormalities in affected persons. With aging, most adults with Down syndrome develop the clinical and neuropathological hallmarks of Alzheimer's disease. Unfortunately, no extant treatments have proven beneficial for cognitive dysfunction for either Down syndrome or Alzheimer’s disease. An incomplete understanding of the common pathogenic mechanisms that link these two disorders has limited researchers’ progress to this end. Common Pathogenic Mechanisms between Down syndrome and Alzheimer's Disease: Steps toward Therapy is a novel attempt to fill this void, by summarizing the work of world-renowned scientists in the field of Alzheimer’s disease and Down syndrome, and thus providing an unprecedented opportunity to attract attention to Down syndrome as a tool for understanding the common molecular mechanisms that underlie Alzheimer’s disease and to develop new therapies for similar neurodegenerative disorders of the brain. The book covers the fundamental pathophysiology and molecular mechanisms behind the incidence of Alzheimer’s disease in Down syndrome affected individuals as well other key topics such as diagnosis and management, in vivo brain imaging studies, and progressive neurodegeneration of the monoaminergic system. The book concludes with a review of recent clinical trials of drugs designed to mitigate cognitive dysfunction in aging adults with Down syndrome and establishes a scientific warrant for the increased testing of candidate pharmacotherapies. Common Pathogenic Mechanisms between Down syndrome and Alzheimer's Disease: Steps toward Therapy is a useful reference clinicians involved in treating Down syndrome patients as well as for neuroscience researchers seeking to understand the influence of a specific case of aneuploidy on Alzheimer’s disease incidence and its progression at the molecular level.

Biomarkers for Alzheimer’s Disease Drug Development

Author : Robert Perneczky
Publisher : Humana
ISBN 13 : 9781071637739
Total Pages : 0 pages
Book Rating : 4.6/5 (377 download)

DOWNLOAD NOW!

Book Synopsis Biomarkers for Alzheimer’s Disease Drug Development by : Robert Perneczky

Download or read book Biomarkers for Alzheimer’s Disease Drug Development written by Robert Perneczky and published by Humana. This book was released on 2024-03-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated volume provides an up-to-date and comprehensive overview of the current state of technologies helping to accelerate Alzheimer’s disease drug development. Addressing the latest advances in preclinical and clinical research, including new insights into the molecular mechanisms and emerging therapeutic strategies, the book continues by exploring digital biomarkers and advanced neuroimaging analysis which will transform how clinical trials in the Alzheimer’s disease field are performed. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice that leads to greater success in the lab or clinic. Authoritative and practical, Biomarkers for Alzheimer’s Disease Drug Development, Second Edition seeks to inspire and inform future efforts to develop effective treatments for this devastating disease.

Neuroprotection in Alzheimer's Disease

Author : Illana Gozes
Publisher : Academic Press
ISBN 13 : 0128037121
Total Pages : 344 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Neuroprotection in Alzheimer's Disease by : Illana Gozes

Download or read book Neuroprotection in Alzheimer's Disease written by Illana Gozes and published by Academic Press. This book was released on 2016-12-30 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease

Alzheimer’s Disease

Author : Ralph W. Richter
Publisher : Springer Science & Business Media
ISBN 13 : 1592596614
Total Pages : 577 pages
Book Rating : 4.5/5 (925 download)

DOWNLOAD NOW!

Book Synopsis Alzheimer’s Disease by : Ralph W. Richter

Download or read book Alzheimer’s Disease written by Ralph W. Richter and published by Springer Science & Business Media. This book was released on 2003-10-10 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease (AD) is a devastating and dehumanizing illness affecting increasingly large numbers of elderly and even middle-aged persons in a worldwide epidemic. Alzheimer’s Disease: A Physician’s Guide to Practical Management was written by selected clinicians and scientists who represent some of the world’s leading centers of excellence in AD research. The editors are proud and grateful for their profound contributions. This book is particularly designed to assist physicians and other health-care professionals in the evaluation, assessment, and treatment of individuals with AD. At the same time, by illuminating the basic scientific background, we hope to provide state-of-the art information about the disease and possible future therapeutic strategies. The recent psychiatric treatment aspects of AD are also clearly presented. Because the early diagnosis of the dementia process is now considered of increasing importance, we focus particularly in several chapters on early changes and preclinical conditions, such as mild cognitive impairment and predementia AD.

Current Status of Natural Products Targeting Alzheimer’s Disease

Author : Syed Shams ul Hassan
Publisher : Frontiers Media SA
ISBN 13 : 2832540074
Total Pages : 162 pages
Book Rating : 4.8/5 (325 download)

DOWNLOAD NOW!

Book Synopsis Current Status of Natural Products Targeting Alzheimer’s Disease by : Syed Shams ul Hassan

Download or read book Current Status of Natural Products Targeting Alzheimer’s Disease written by Syed Shams ul Hassan and published by Frontiers Media SA. This book was released on 2023-12-08 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite more than fifty years of intensive research on Alzheimer’s disease (AD) drug discovery, up till now only four medicines are approved by FDA for its treatment; among which three are acetylcholinesterase (AChE) inhibitors (donepezil, galantamine, and rivastigmine) and one is N-Methyl-D-aspartate (NMDA) antagonist memantine. These medications were launched during the initial research for AD but were not able to provide satisfactory results because of their limited efficacy and numerous side effects. The high-profile failure of late-stage clinical trials by prominent pharma firms for biomolecules that showed promising results in experimental models has added to the dissatisfaction of drug development research for AD in recent years. The global dementia patient population was expected to be 50 million in 2017, with projections of 82 million and 152 million in 2030 and 2045, respectively. There is a significant flaw in our understanding of AD pathology, as well as in the experimental models we use to depict human pathology and our therapeutic methods. In light of this, this Research Topic is created to highlight the critical significance of natural products in therapeutic development for human diseases. The therapeutic potential of several natural products, including crude extracts and purified compounds, has been demonstrated in numerous experimental models, with pharmacological efficacy comparable to that of known medicines. This includes effects via specific biological targets (enzymes, receptors, ion channels, and so on) or a variety of mechanisms extending from basic antioxidants and anti-inflammatory mechanisms to neuroprotection and neuroregeneration pathways. Insights into AD therapy using natural products in the form of original research articles or reviews in all areas of AD pathology, experimental designs, and therapeutic approaches are encouraged. The main goal of this collection is to put light on the current status of natural products in AD. As natural products including many polyphenols or other agents are given in combination with marketed available AD drugs to increase their efficacy. So, all those research areas that cover the current status of natural products in single or in combination with other agents to improve the efficacy of AD/dementia will be focused on. • Natural products targeting AD (In-vitro, in-vivo, and in-silico); • Drug discovery for AD by targeting pathways; • Combination therapy to improve the efficacy of Anti-AD agents; • Polytherapy vs single chemical entity; • Experimental models of dementia; • Novel bioassays for cognitive disorders.