The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387464018
Total Pages : 502 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease by : Bharat B. Aggarwal

Download or read book The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease written by Bharat B. Aggarwal and published by Springer Science & Business Media. This book was released on 2007-08-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Curcumin in Health and Disease

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Author :
Publisher : MDPI
ISBN 13 : 3039214497
Total Pages : 274 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Curcumin in Health and Disease by : Beatrice E. Bachmeier

Download or read book Curcumin in Health and Disease written by Beatrice E. Bachmeier and published by MDPI. This book was released on 2019-10-11 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.

Curcumin and Its Role in Health and Disease

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (869 download)

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Book Synopsis Curcumin and Its Role in Health and Disease by : Kathryn Woltjer

Download or read book Curcumin and Its Role in Health and Disease written by Kathryn Woltjer and published by . This book was released on 2023-03-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains eight chapters discussing curcumin and its role in health and disease. Chapter One evaluates curcumin's role in cancer prevention. Chapter Two reviews curcumin's function as a natural systemic disease modulator. Chapter Three looks at the effects of curcumin supplantation and exercise training on Alzheimer's disease and age-associated cognitive decline. Chapter Four focuses on the antiviral effects of curcumin, with a special emphasis on COVID-19. Chapter Five examines green extraction techniques for curcumin, synthetic approaches, as well as its anti-inflammatory, anti-oxidant, and anti-neoplastic effects. Chapter Six reviews the possible effects of immune responses to the preventive combined effects of exercise training and curcumin supplementation in chronic disease. Chapter Seven is a mini review of the essential therapeutic effects of curcumin. The eighth and final chapter examines the promises and challenges of curcumin in medical research.

Herbal Drugs: Ethnomedicine to Modern Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 3540791167
Total Pages : 414 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Herbal Drugs: Ethnomedicine to Modern Medicine by : Kishan Gopal Ramawat

Download or read book Herbal Drugs: Ethnomedicine to Modern Medicine written by Kishan Gopal Ramawat and published by Springer Science & Business Media. This book was released on 2008-11-25 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considerable progress has been made in our healthcare system, in particular with respect to sensitive diagnostic tools, reagents and very effective and precise drugs. On the other hand, high-throughput screening technology can screen vast numbers of compounds against an array of targets in a very short time, and leads thus - tained can be further explored. In developing countries, the exploding population exerts pressure not only on natural resources but also on the human population - self, whose members strive to become successful and advance in society. This leads to increased blood pressure, anxiety, obesity-associated lipid disorders, cardiov- cular diseases and diabetes. Most of these diseases result in disturbed family life, including sexual behaviour. Despite technological developments, herbal drugs still occupy a preferential place in a majority of the population in the Third World and terminal patients in the West. Herbal drugs, in addition to being cost effective and easily accessible, have been used since time immemorial and have passed the test of time without having any side effects. The multitarget effects of herbs (holistic approaches) are the fun- mental basis of their utilization. This approach is already used in traditional systems of medicine like Ayurveda, which has become more popular in the West in recent years. However, the integration of modern science with traditional uses of herbal drugs is of the utmost importance if ones wishes to use ancient knowledge for the betterment of humanity.

Nutrition and Wound Healing

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Publisher : CRC Press
ISBN 13 : 0203500237
Total Pages : 384 pages
Book Rating : 4.2/5 (35 download)

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Book Synopsis Nutrition and Wound Healing by : Joseph A. Molnar MD PhD FACS

Download or read book Nutrition and Wound Healing written by Joseph A. Molnar MD PhD FACS and published by CRC Press. This book was released on 2006-10-25 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: With mounting evidence regarding the role of poor nutrition in the development of chronic diseases such as heart disease and diabetes, it is no secret that appropriate nutrition is crucial to optimal health. Achieving the correct balance of elements provides the body with the ability to adapt to a shifting and often hazardous environment. Never is

Turmeric for Health

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Publisher : Simon and Schuster
ISBN 13 : 1440594686
Total Pages : 128 pages
Book Rating : 4.4/5 (45 download)

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Book Synopsis Turmeric for Health by : Britt Brandon

Download or read book Turmeric for Health written by Britt Brandon and published by Simon and Schuster. This book was released on 2016-09-02 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the power of turmeric! For centuries, turmeric, the spice that gives curry its yellow color and its distinctive warm and earthy flavor, has been used in eastern medicine traditions as an anti-inflammatory and pain-relieving remedy. Now, new medical studies are confirming this wisdom--and adding to it. Turmeric contains powerful antioxidants, which can help combat chronic life-threatening diseases, including heart disease, certain types of cancer, arthritis, Parkinson's disease, and Alzheimer's disease. It's also an all-natural remedy for common ailments and an effective health and beauty aid. Turmeric for Health provides 100 all-natural solutions that help: Soothe digestive upset Relieve daily aches and pains and reduce inflammation Improve metabolic function and weight loss Promote healthy skin, hair, and nails With Turmeric for Health, you'll discover all the benefits that this simple spice can bring--without dangerous chemicals or costly procedures.

Turmeric

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Publisher : CRC Press
ISBN 13 : 1420006320
Total Pages : 506 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Turmeric by : P. N. Ravindran

Download or read book Turmeric written by P. N. Ravindran and published by CRC Press. This book was released on 2007-03-01 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the last 6000 years turmeric has been used in Ayurvedic medicine to alleviate pain, balance digestion, purify body and mind, clear skin diseases, expel phlegm, and invigorate the blood. Nowadays, this plant has acquired great importance with its anti-aging, anti-cancer, anti-Altzheimer, antioxidant, and a variety of other medicinal properties.

Curcumin

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Publisher :
ISBN 13 : 9781633213197
Total Pages : 548 pages
Book Rating : 4.2/5 (131 download)

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Book Synopsis Curcumin by : Daniel Loïc Pouliquen

Download or read book Curcumin written by Daniel Loïc Pouliquen and published by . This book was released on 2014-01-01 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examples of plant-derived pharmaceuticals that have become the focus of continuous and exponential research and development interest have, to date, been somewhat scarce. After a long period, the last two decades have been characterized by a 100-fold increase in the number of scientific articles published annually that are of relevance to the use of curcumin in biomedicine. Today, the already-wide spectrum of potential clinical applications of this natural drug and its synthetic derivatives continues to grow, including chemoprevention and the treatment of cancers, inflammatory and immune diseases, diabetes, bacterial and viral infections, parasitosis, and cardiovascular and neurodegenerative diseases. Over the last two decades, numerous findings have confirmed the safety of curcumin, both in preclinical and clinical studies. Its physicochemical properties, low bioavailability and rapid metabolism have, however, somewhat limited its potential therapeutic applications. To overcome these limitations, the last few years have seen an impressive development of research on analogs, prodrugs and nanostructured systems, a number of which are already demonstrating improved properties compared with the parent structure. In parallel, new administration routes have been explored, and additional pharmacological properties have been documented, leading in particular to promising prospects for pain management.

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

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Author :
Publisher : Springer
ISBN 13 : 9780387516493
Total Pages : 0 pages
Book Rating : 4.5/5 (164 download)

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Book Synopsis The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease by : Bharat B. Aggarwal

Download or read book The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease written by Bharat B. Aggarwal and published by Springer. This book was released on 2008-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Handbook of Dietary Phytochemicals

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Publisher : Springer
ISBN 13 : 9789811541476
Total Pages : 1953 pages
Book Rating : 4.5/5 (414 download)

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Book Synopsis Handbook of Dietary Phytochemicals by : Jianbo Xiao

Download or read book Handbook of Dietary Phytochemicals written by Jianbo Xiao and published by Springer. This book was released on 2021-09-02 with total page 1953 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes recent advances in the chemistry, bioactivity, nutrition, and functional aspects of dietary phytochemicals, as well as the health and functional aspects of foods rich in phytochemicals. Consisting of forty-four chapters, it discusses the different chemical types of phytochemicals in our diets and food and presents data collected from animal or human experiments that are directly related to human health. Each chapter covers the chemistry, epidemiological study, bioavailability, bioactivity (animal experiments) function in humans and safety, as well as products on the market. Moreover, the more than 200 figures make it easy to grasp the main findings in each area.

Curcumin and Neurodegenerative Diseases

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Publisher : Springer
ISBN 13 : 9789819977307
Total Pages : 0 pages
Book Rating : 4.9/5 (773 download)

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Book Synopsis Curcumin and Neurodegenerative Diseases by : Mahendra Rai

Download or read book Curcumin and Neurodegenerative Diseases written by Mahendra Rai and published by Springer. This book was released on 2024-03-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the potential benefits of turmeric, and specifically curcumin, in the treatment and prevention of neurodegenerative diseases. The book covers various aspects of turmeric, including its traditional use in Ayurveda and Chinese medicine, secondary metabolites, curcuminoids, and sesquiterpenoids found in turmeric, as well as the use of nano curcumin in neurodegenerative diseases. It discusses the different ways in which turmeric can be used to treat neurodegenerative diseases, including as a therapy for brain diseases, curcumin-induced neuroprotection in cerebral ischemia, and neural stem cell therapy in combination with curcumin. It also discusses the role of nano curcumin in neurodegenerative diseases, including its potential use in the treatment of Alzheimer's disease. The book provides the scientific evidence behind the use of turmeric and its compounds in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Overall, this book is an invaluable resource for researchers and healthcare professionals interested in exploring the potential benefits of turmeric and curcumin in the treatment and prevention of neurodegenerative diseases.

Plants Consumed by Man

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Publisher :
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Plants Consumed by Man by : B. Brouk

Download or read book Plants Consumed by Man written by B. Brouk and published by . This book was released on 1975 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction; Cereals and pseudo-cereals; Vegetables; Fruit; Nuts; Plant extracts; Flavouring plants; Beverage plants; Fumitories and masticatories; Fermentative micro-organisms.

Curcumin

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Publisher : Nova Science Publishers
ISBN 13 : 9781619424876
Total Pages : 278 pages
Book Rating : 4.4/5 (248 download)

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Book Synopsis Curcumin by : Jun Sasaki

Download or read book Curcumin written by Jun Sasaki and published by Nova Science Publishers. This book was released on 2012-05-01 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Curcumin is a natural product found in the rhizome of Curcuma longa. Ongoing research and clinical trials prove this natural phenolic compound to possess diverse pharmacological potency and is effective as an antioxidant, anti-inflammatory, antimicrobial/antiviral property and is also being considered as a cancer chemo-preventive agent. Topics discussed in this book include the implications of curcumin treatment of central nervous system disease; phosphorylase kinase inhibition in skin disease; PEGylated curcumin; the potential role of curcumin as a chemotherapeutic drug and the pharmaceutical implications of curcumin in the development of drugs for cystic fibrosis pharmacotherapy.

Advanced Pharmacological Uses of Medicinal Plants and Natural Products

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Publisher : IGI Global
ISBN 13 : 1799820955
Total Pages : 442 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Advanced Pharmacological Uses of Medicinal Plants and Natural Products by : Singh, Ajeet

Download or read book Advanced Pharmacological Uses of Medicinal Plants and Natural Products written by Singh, Ajeet and published by IGI Global. This book was released on 2020-02-21 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: A vast majority of the world’s population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services. Advanced Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.

WHO Monographs on Selected Medicinal Plants

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Publisher : World Health Organization
ISBN 13 : 9789241545372
Total Pages : 392 pages
Book Rating : 4.5/5 (453 download)

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Book Synopsis WHO Monographs on Selected Medicinal Plants by : World Health Organization

Download or read book WHO Monographs on Selected Medicinal Plants written by World Health Organization and published by World Health Organization. This book was released on 1999 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume in a series of monographs which are intended to promote information exchange and international harmonised standards for the quality control and use of herbal medicines. It contains scientific information on 30 selected plants, and each entry includes a pharmacopoeial summary for quality assurance purposes, information on its clinical application and sections on contraindications, pharmacology, safety issues, and dosage forms. It provides two cumulative indexes with entries in alphabetical order by plant name and according to the plant material of interest.

Herbal Medicine

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Publisher : CRC Press
ISBN 13 : 1439807167
Total Pages : 500 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Herbal Medicine by : Iris F. F. Benzie

Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Molecular Targets and Therapeutic Uses of Spices

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Author :
Publisher : World Scientific
ISBN 13 : 9812837906
Total Pages : 457 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis Molecular Targets and Therapeutic Uses of Spices by : Bharat B. Aggarwal

Download or read book Molecular Targets and Therapeutic Uses of Spices written by Bharat B. Aggarwal and published by World Scientific. This book was released on 2009 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional uses of spices : an overview / Ajaikumar B. Kunnumakkara ... [et al.] -- Black pepper (Piper nigrum) and its bioactive compound, piperine / Krishnapura Srinivasan -- Cardamom (Elettaria cardamomum) and its active constituent, 1,8-cineole / Archana Sengupta and Shamee Bhattacharjee -- Molecular targets and health benefits of cinnamon / Kiran Panickar ... [et al.] -- Cloves (eugenol) / Yoshinori Kadoma ... [et al.] -- Coriander / Sanjeev Shukla and Sanjay Gupta -- Fenugreek (diosgenin) / Jayadev Raju and Chinthalapally V. Rao -- Diallyl sulfide from garlic / Girija Kuttan and Punathil Thejass -- Ginger (6-gingerol) / Nidhi Nigam, Jasmine George, and Yogeshwer Shukla -- Kalonji (thymoquinone) / Ahmed O. Kaseb and Abdel-Hafez A. Selim -- Kokum (garcinol) / Manoj K. Pandey, Ajaikumar B. Kunnumakkara, and Bharat B. Aggarwal -- Capsaicin : a hot spice in the chemoprevention of cancer / Joydeb Kumar Kundu and Young-Joon Surh -- Rosemary (rosmarinic acid) / Jongsung Lee ... [et al.] -- Mint and its constituents / Ajaikumar B. Kunnumakkara ... [et al.] -- Turmeric (curcumin) / Jen-Kun Lin and Shoei-Yn Lin Shiau.