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Critical Thinking In Clinical Research
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Book Synopsis Critical Thinking in Clinical Research by : Felipe Fregni
Download or read book Critical Thinking in Clinical Research written by Felipe Fregni and published by Oxford University Press. This book was released on 2018 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical Thinking in Clinical Research explains the fundamentals of clinical research in a case-based approach. The core concept is to combine a clear and concise transfer of information and knowledge with an engagement of the reader to develop a mastery of learning and critical thinking skills. The book addresses the main concepts of clinical research, basics of biostatistics, advanced topics in applied biostatistics, and practical aspects of clinical research, with emphasis on clinical relevance across all medical specialties.
Book Synopsis Evidence-based Practice by : Milos Jenicek
Download or read book Evidence-based Practice written by Milos Jenicek and published by Amer Medical Assn. This book was released on 2005 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence-Based Practice: Logic and Critical Thinking in Medicine provides easy access to fundamental principles, quickly assimilated techniques, and proven, rigorous application that demonstrates how logic and critical thinking are applied to the medical thinking process. This marriage allows health professionals to understand the critical use of evidence logically and in a structured, methodological way to make medical decisions. Such uses of evidence are the essence of Evidence-Based Practice as reflected in the spirit of this book. In order to ensure better patient outcomes, physicians have to learn how rational, practical uses of evidence allow organized decision-making in practice and research. In a textbook format, Evidence-Based Practice: Logic and Critical Thinking in Medicine offers the reader principles and techniques in Part One. Part Two shows the application of logic and critical thinking to clinical problem solving in practice, medical research, and public health.
Book Synopsis Clinical Research Transformed by : Olli S. Miettinen
Download or read book Clinical Research Transformed written by Olli S. Miettinen and published by Springer Nature. This book was released on 2019-10-15 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Information Age, the practices of clinical medicine should no longer be based on what clinical doctors actively know. Rather, all of the importantly practice-relevant knowledge should not only already exist but also be codified in cyberspace, in directly practice-guiding 'expert systems' -- for the benefit of both doctors and patients everywhere. Each of these systems (discipline-specific) would, prompted by a particular type of case presentation, present the doctor a questionnaire specific to cases of the type at issue, and document the doctor's answers to the questions. If at issue would be a case of complaint about a (particular type of) sickness, the system would translate the resulting diagnostic profile of the case into the corresponding probabilities of the illnesses to be considered. Similarly, if at issue would be an already-diagnosed case of a particular illness, the system would ask about, and record, the relevant elements in the prognostic profile of the case and then translate this profile into the probabilities of various outcomes to be considered, probabilities specific to the choice of treatment and prospective time in addition to that profile. And besides, these systems would analogously address the causal origin -- etiogenesis -- of cases of particular types of illness. While the requisite knowledge-base for these systems -- notably for the probabilities in them -- has not been addressed by such 'patient-oriented' clinical research as has been conducted (very extensively) up to now, this book delineates the nature of the suitably-transformed research (gnostic). The critically-transformative innovation in the research is the studies' focus on Gnostic Probability Functions -- dia-, etio-, and prognostic -- in the framework of logistic regression models. This book also presents a vision of how this critically-transformative research would most expeditiously be provided for and also conducted, among select sets of academic teaching hospitals.
Book Synopsis The Quintessence of Basic and Clinical Research and Scientific Publishing by : Gowraganahalli Jagadeesh
Download or read book The Quintessence of Basic and Clinical Research and Scientific Publishing written by Gowraganahalli Jagadeesh and published by Springer Nature. This book was released on 2023-11-01 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clinical trial design to acquire substantial evidence of efficacy and safety for candidate drugs in the target patient population. New and evolving topics such as artificial intelligence, machine and deep learning, drug repurposing approaches, and bioinformatics, are incorporated into the text as these features are becoming integrated into drug research and development. Additionally, it covers publication strategies, including literature search, manuscript preparation, data presentation, relevant discussion, editorial processes, elements of peer review, and bibliometrics. Finally, the book addresses grantsmanship, key strategies for building effective networks, mentorships, maintaining research integrity, and forging career advancement opportunities, including entrepreneurship.
Book Synopsis Critical Thinking in Clinical Practice by : Eileen Gambrill
Download or read book Critical Thinking in Clinical Practice written by Eileen Gambrill and published by John Wiley & Sons. This book was released on 2012-04-26 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for Critical Thinking in Clinical Practice, Third Edition "Eileen Gambrill is unparalleled in her ability to describe common flaws and biases in clinical decision making. The result in this revised edition is a steadfast call for change that also acknowledges the demands of practice. A must-read for clinicians and researchers alike." —Elizabeth K. Anthony, PhD, Assistant Professor, School of Social Work, Arizona State University "This Third Edition builds upon the impressive strengths of Gambrill's prior treatments of the topic to support the notion that critical thinking is a teachable skill and one essential for contemporary practice in the human services. This book should be the default authority on the topic of critical thinking for human service professionals and would be an excellent textbook." —Bruce A. Thyer, PhD, LCSW, Professor and former Dean, Florida State University College of Social Work "I was skeptical about how Critical Thinking in Clinical Practice could be improved, but Eileen Gambrill has succeeded! Her articulation of critical thinking skills for clinical decisions ultimately will benefit the people we serve." —Joanne Yaffe, PhD, ACSW, Associate Professor of Social Work and Adjunct Associate Professor of Psychiatry, University of Utah A balanced and illustrative guide to incorporating critical-thinking values, knowledge, and skills into clinical education and practice Now in a third edition, Critical Thinking in Clinical Practice is written for helping professionals who want to think more clearly about the decisions they make and the context in which they make them. It is a practical volume for clinicians who would like to expand their knowledge of common pitfalls and fallacies in clinical reasoning. As in earlier editions, this Third Edition draws on research related to problem solving and decision making, illustrating the relevance of research findings to everyday clinical practice and policy. Revised throughout, the new edition includes discussion of: The influence of pharmaceutical companies on the helping professions, including disease mongering—the creation of bogus risks, problems, and needless worries Different kinds of propaganda in the helping professions that compromise informed consent Additional coverage of classification, pathology, reliance on authority, and hazards in data collection The development of decision aids of value to both professionals and clients The relative contribution of specific interventions compared to nonspecific factors to positive outcome Factors related to decision making in multidisciplinary teams New developments regarding intuitive and analytic reasoning The pragmatic theory of fallacies Designed to enhance the quality of services offered to clients, Critical Thinking in Clinical Practice, Third Edition is filled with insightful examples, useful lists, websites, and guidelines, presenting an essential resource for all helping professionals and students in the helping professions.
Book Synopsis Clinical Research by : Manfred Stommel
Download or read book Clinical Research written by Manfred Stommel and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique textbook integrates statistical concepts into evidence-based clinical practice and patient management. Research concepts and techniques are drawn from epidemiology, bio-statistics, and psychometrics, as well as educational and social science research. Clinical examples throughout the text illustrate practical and scientifically sound applications of the concepts. Data tables and research vignettes highlight statistical distributions involving probability. Methods to locate and utilize web-based information relevant to clinical research are discussed, and web URLs are provided. Further learning is encouraged by the inclusion of suggested activities, recommended readings, references, and a comprehensive glossary of research terms. Additional resources are available at a Connection Website, connection.LWW.com/go/stommel.
Book Synopsis Designing Clinical Research by : Stephen B. Hulley
Download or read book Designing Clinical Research written by Stephen B. Hulley and published by Lippincott Williams & Wilkins. This book was released on 2011-11-30 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.
Book Synopsis Principles and Practice of Clinical Research by : John I. Gallin
Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Academic Press. This book was released on 2012-05-31 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expanded third edition provides an introduction to the conduct of clinical research as well as more comprehensive and expansive content about the infrastructure necessary for a successful clinical research organization or enterprise. With authors who are experts in clinical research in both the public and private sectors, this publication provides essential information to clinical investigators who wish to develop and conduct well designed patient-based research protocols that comply with rigorous study design, ethical, and regulatory requirements.
Book Synopsis The Thinker's Guide to Clinical Reasoning by : David Hawkins
Download or read book The Thinker's Guide to Clinical Reasoning written by David Hawkins and published by Rowman & Littlefield. This book was released on 2019-06-01 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the Thinker’s Guide Library introduces healthcare students and professionals to the foundations of critical thinking and offers examples of applications within clinical fields. It is an essential companion for all healthcare courses as it advances critical thinking within all specialties with the clinical professions.
Book Synopsis Critical Thinking, Clinical Reasoning and Clinical Judgment by :
Download or read book Critical Thinking, Clinical Reasoning and Clinical Judgment written by and published by Elsevier Health Sciences. This book was released on 2016-01-01 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Issues in Clinical Medicine Research and Practice: 2013 Edition by :
Download or read book Issues in Clinical Medicine Research and Practice: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Clinical Medicine Research and Practice: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Clinical Endocrinology. The editors have built Issues in Clinical Medicine Research and Practice: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Clinical Endocrinology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Clinical Medicine Research and Practice: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis All About Clinical Research: Word Search and Flash Cards for Ich Guidelines for Good Clinical Practice by : Solar Biomedical
Download or read book All About Clinical Research: Word Search and Flash Cards for Ich Guidelines for Good Clinical Practice written by Solar Biomedical and published by iUniverse. This book was released on 2023-02-13 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to provide novice and experienced clinical research professionals with a fun and effective way of learning and remembering the information found in ICH guidelines for Good Clinical Practice through word searches and flash cards. • Use the word search activities to help with word associations to help focus on and learn the different parts of the ICH Guidelines for Good Clinical Practice. The consolidated tripartite harmonized ICH- Good Clinical Practice [E6 (R2) – the Integrated Addendum to E6(R1)], General Considerations for Clinical Trials [E8 (R1)], and Clinical Safety Data Management (E2A), as published in the U.S. Federal Register May 9, 1997 and March 1, 1995 respectively, are attached to this book for your easy reference when solving the word search puzzles. • Use the flash cards as a tool for remembering specific GCP rules and CFR regulations in clinical research.
Book Synopsis An Introduction to Clinical Research for Health and Social Care Professionals by : Ario Santini
Download or read book An Introduction to Clinical Research for Health and Social Care Professionals written by Ario Santini and published by AuthorHouse. This book was released on 2022-05-22 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the increasing emphasis on evidence-based practice, there is a need for all health and social care professionals to understand the principles of general and clinical research. In the United Kingdom and several other countries, this had led to a proliferation of advanced programs, including for those seeking doctorate degrees. In this book, the editors introduce readers to the principles and practice of clinical research. Eighteen chapters and three appendices provide guidance on the different stages of a research project, from inception to the dissemination of results. Topics include: • steps to engage in practice-based research; • ethical questions surrounding research; • sources of funding; • collecting and collating data. Contributing authors emphasize the need to critically appraise literature before carrying out a research project. They also explain the stages of a research project and share insights on where to go for more information. The book includes an index, a glossary, and charts and figures to promote learning. Discussion questions reinforce critical material.
Book Synopsis Guide to Paediatric Drug Development and Clinical Research by : K. Rose
Download or read book Guide to Paediatric Drug Development and Clinical Research written by K. Rose and published by Karger Medical and Scientific Publishers. This book was released on 2010-05-21 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children in the developed world have never enjoyed better medical care: mortality has decreased and many fatal diseases of the past can today be prevented or even cured. However, the current practice of pharmacotherapy in children does not reflect existing scientific knowledge and has come under scrutiny by paediatricians, pharmacists and regulatory authorities. In order to advance the development of medicines tailored to paediatric needs, US and EU legislators have taken action, and the WHO has initiated a global paediatric campaign. This book gives an overview over the worldwide activities that increasingly include children in the development of new medicines. Triggered by both a better understanding of how the child’s body develops as well as recent legislation in the USA and in Europe, this comprises dosing, ethics, age-appropriate pharmaceutical forms and clinical trials, to name just a few aspects. A wide spectrum of readers will profit from this book, including paediatricians, pharmacists, general practitioners and health care professionals involved in child care and paediatric research, clinical trial personnel, patient advocacy groups, ethics committees, politicians, parents and interested lay persons.
Book Synopsis Careers in Clinical Research by : Institute of Medicine
Download or read book Careers in Clinical Research written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transforming biological discoveries into medical treatment calls for a cadre of health professionals skilled in patient-oriented research. Yet many factors discourage talented persons from choosing clinical research as a profession. This new volume lays out the problem in detail, with specific recommendations to the federal government, the biotechnology and pharmaceutical industries, professional organizations, the health care industry, organized medicine, and the nation's universities and academic health centers. The volume explores How clinical research is conducted, what human resources are available, and what research opportunities lie ahead. Why health professionals become discouraged about clinical research. How the educational system has failed in this area and what programs stand out as models. How funding affects the supply of researchers. This practical book will be of immediate interest to public and private agencies funding research, research administrators, medical educators, health professionals, and those pursuing a career in clinical investigation.
Book Synopsis A Primer on Clinical Experience in Medicine by : Milos Jenicek, MD
Download or read book A Primer on Clinical Experience in Medicine written by Milos Jenicek, MD and published by CRC Press. This book was released on 2012-08-08 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mastery of quality health care and patient safety begins as soon as we open the hospital doors for the first time and start acquiring practical experience. The acquisition of such experience includes much more than the development of sensorimotor skills and basic knowledge of the sciences. It relies on effective reasoning, decision making, and communication shared by all health professionals, including physicians, nurses, dentists, pharmacists, physiotherapists, and administrators. A Primer on Clinical Experience in Medicine: Reasoning, Decision Making, and Communication in Health Sciences is about these essential skills. It describes how physicians and health professionals reason, make decisions, and practice medicine. Covering the basic considerations related to clinical and caregiver reasoning, it lays out a roadmap to help those new to health care as well as seasoned veterans overcome the complexities of working for the well-being of those who trust us with their physical, mental, and spiritual health. The book provides a step-by-step breakdown of the reasoning process for clinical work and clinical care. It examines both general and medical ways of thinking, reasoning, argumentation, fact finding, and using evidence. Outlining the fundamentals of decision making, it integrates coverage of clinical reasoning, risk assessment, diagnosis, treatment, and prognosis in evidence-based medicine. It also: Describes how to evaluate the success (effectiveness and cure) and failure (error and harm) of clinical and community actions Considers communication with patients and outlines strategies, successes, failures, and possible remedies—including offices, bedside, intervention, and care settings Examines strategies, successes, failures, and possible remedies for communication with peers—including interpersonal communication, morning reports, rounds, and research gatherings The book describes vehicles, opportunities, and environments for enhanced professional communication, including patient interviews, clinical case reports, and morning reports. It includes numerous examples that demonstrate the importance of sound reasoning, decision making, and communication and also considers future implications for research, management, planning, and evaluation.
Book Synopsis Clinical Trials by : Steven Piantadosi
Download or read book Clinical Trials written by Steven Piantadosi and published by John Wiley & Sons. This book was released on 2017-08-28 with total page 931 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studies This Third Edition builds on the text’s reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials. Readers will encounter the principles of design for various types of clinical trials, and are then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides common sense solutions. All stages of therapeutic development are discussed in detail, and the methods are not restricted to a single clinical application area. The authors bases current revisions and updates on his own experience, classroom instruction, and feedback from teachers and medical and statistical professionals involved in clinical trials. The Third Edition greatly expands its coverage, ranging from statistical principles to new and provocative topics, including alternative medicine and ethics, middle development, comparative studies, and adaptive designs. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First and Second Editions will discover revamped exercise sets; an updated and extensive reference section; new material on endpoints and the developmental pipeline, among others; and revisions of numerous sections. In addition, this book: • Features accessible and broad coverage of statistical design methods—the crucial building blocks of clinical trials and medical research -- now complete with new chapters on overall development, middle development, comparative studies, and adaptive designs • Teaches readers to design clinical trials that produce valid qualitative results backed by rigorous statistical methods • Contains an introduction and summary in each chapter to reinforce key points • Includes discussion questions to stimulate critical thinking and help readers understand how they can apply their newfound knowledge • Provides extensive references to direct readers to the most recent literature, and there are numerous new or revised exercises throughout the book Clinical Trials: A Methodologic Perspective, Third Edition is a textbook accessible to advanced undergraduate students in the quantitative sciences, graduate students in public health and the life sciences, physicians training in clinical research methods, and biostatisticians and epidemiologists. This book is accompanied by downloadable files available below under the DOWNLOADS tab. These files include: MATHEMATICA program – A set of downloadable files that tracks the chapters, containing code pertaining to each. SAS PROGRAMS and DATA FILES used in the book. The following software programs, included in the downloadables, were developed by the author, Steven Piantadosi, M.D., Ph.D: RANDOMIZATION – This program generates treatment assignments for a clinical trial using blocked stratified randomization. CRM – Implements the continual reassessment methods for dose finding clinical trials. OPTIMAL – Calculates two-stage optimal phase II designs using the Simon method. POWER – This is a power and sample size program for clinical trials. Executables for installing these programs can also be found at https://risccweb.csmc.edu/biostats/. Steven Piantadosi, MD, PhD, is the Phase One Foundation Distinguished Chair and Director of the Samuel Oschin Cancer Institute, and Professor of Medicine at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Piantadosi is one of the world’s leading experts in the design and analysis of clinical trials for cancer research. He has taught clinical trials methods extensively in formal courses and short venues. He has advised numerous academic programs and collaborations nationally regarding clinical trial design and conduct, and has served on external advisory boards for the National Institutes of Health and other prominent cancer programs and centers. The author of more than 260 peer-reviewed scientific articles, Dr. Piantadosi has published extensively on research results, clinical applications, and trial methodology. While his papers have contributed to many areas of oncology, he has also collaborated on diverse studies outside oncology including lung disease and degenerative neurological disease.
