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Author : Martin Edwards
Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.:/5 (779 download)
Download or read book Control and the Therapeutic Trial, 1918-1948 written by Martin Edwards and published by . This book was released on 2004 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Martin Edwards
Publisher : BRILL
ISBN 13 : 9401204942
Total Pages : 227 pages
Book Rating : 4.4/5 (12 download)
Download or read book Control and the Therapeutic Trial written by Martin Edwards and published by BRILL. This book was released on 2015-07-14 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Listen to podcast with the author How do doctors decide whether their drugs, or other treatments, actually work? In practice this can be fiendishly difficult. Nowadays the gold standard is the randomised controlled trial (RCT). But the RCT is a recent invention, and the story of how it came to dominate therapeutic evaluation from the latter half of the twentieth century involves acrimony, confrontation, and manipulation of the powerful rhetoric of ‘control’. Control and the Therapeutic Trial examines the development of the RCT from the eclectic collection of methodologies available to practitioners in the early-twentieth century. In particular, it explores the British Medical Research Council’s (MRC) exploitation of the term ‘controlled’ to help establish its own ‘controlled trials’ as the gold standard for therapeutic evaluation, and, ultimately, the MRC itself as the proper authority to adjudicate on therapeutic efficacy. This rhetorical power still clings, and is exploited today. Control and the Therapeutic Trial will be of interest not only to historians of twentieth-century medicine and practising clinicians who take therapeutic decisions, but to anyone who seeks a broader insight into the forces that shaped, and control, the modern controlled trial.
Author : Noortje Jacobs
Publisher : University of Chicago Press
ISBN 13 : 0226819310
Total Pages : 305 pages
Book Rating : 4.2/5 (268 download)
Download or read book Ethics by Committee written by Noortje Jacobs and published by University of Chicago Press. This book was released on 2022-08-26 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: How liberal democracies in the late twentieth century have sought to resolve public concerns over charged issues in medicine and science. Ethics boards have become obligatory passage points in today’s medical science, and we forget how novel they really are. The use of humans in experiments is an age-old practice that records show goes back to at least the third century BC, and it has been popular as a practice since the early modern period. Yet in most countries around the world, hardly any formal checks and balances existed to govern the communal oversight of experiments involving human subjects until at least the 1960s. Ethics by Committee traces the rise of ethics boards for human experimentation in the second half of the twentieth century. Using the Netherlands as a case study, historian Noortje Jacobs shows how the authority of physicians to make decisions about clinical research in this period gave way in most developed nations to formal mechanisms of communal decision-making that served to regiment the behavior of individual researchers. This historically unprecedented change in scientific governance came out of the growing international wariness of medical research in the decades after World War II and was meant to solidify a new way of reasoning together in liberal democracies about medicine and science. But what reasoning together meant, and who was invited to participate, changed drastically over time. In detailing this history, Jacobs shows that research ethics committees were originally intended not only to make human experimentation more ethical but also to raise its epistemic quality and intensify the use of new clinical research methods. By examining complex negotiations over the appropriate governance of human subjects research, Ethics by Committee is an important contribution to our understanding of the randomized controlled trial and the history of research ethics and bioethics more generally.
Author : Angela Cassidy
Publisher : Springer Nature
ISBN 13 : 3030191869
Total Pages : 375 pages
Book Rating : 4.0/5 (31 download)
Download or read book Vermin, Victims and Disease written by Angela Cassidy and published by Springer Nature. This book was released on 2019-09-25 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides the first critical history of the controversy over whether to cull wild badgers to control the spread of bovine tuberculosis (bTB) in British cattle. This question has plagued several professional generations of politicians, policymakers, experts and campaigners since the early 1970s. Questions of what is known, who knows, who cares, who to trust and what to do about this complex problem have been the source of scientific, policy, and increasingly vociferous public debate ever since. This book integrates contemporary history, science and technology studies, human-animal relations, and policy research to conduct a cross-cutting analysis. It explores the worldviews of those involved with animal health, disease ecology and badger protection between the 1970s and 1990s, before reintegrating them to investigate the recent public polarisation of the controversy. Finally it asks how we might move beyond the current impasse.
Author : Eve Colpus
Publisher : Bloomsbury Publishing
ISBN 13 : 1474259693
Total Pages : 307 pages
Book Rating : 4.4/5 (742 download)
Download or read book Female Philanthropy in the Interwar World written by Eve Colpus and published by Bloomsbury Publishing. This book was released on 2018-02-08 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Female philanthropy was at the heart of transformative thinking about society and the role of individuals in the interwar period. In Britain, in the aftermath of the First World War, professionalization; the authority of the social sciences; mass democracy; internationalism; and new media sounded the future and, for many, the death knell of elite practices of benevolence. Eve Colpus tells a new story about a world in which female philanthropists reshaped personal models of charity for modern projects of social connectedness, and new forms of cultural and political encounter. Centering the stories of four remarkable British-born women - Evangeline Booth; Lettice Fisher; Emily Kinnaird; and Muriel Paget - Colpus recaptures the breadth of the social, cultural and political influence of women's philanthropy upon practices of social activism. Female Philanthropy in the Interwar World is not only a new history of women's civic agency in the interwar period, but also a study of how female philanthropists explored approaches to identification and cultural difference that emphasized friendship in relation to interwar modernity. Richly detailed, the book's perspective on women's social interventionism offers a new reading of the centrality of personal relationships to philanthropy that can inform alternative models of giving today.
Author : Fred Gifford
Publisher : Elsevier
ISBN 13 : 0444517871
Total Pages : 601 pages
Book Rating : 4.4/5 (445 download)
Download or read book Philosophy of Medicine written by Fred Gifford and published by Elsevier. This book was released on 2011-08-23 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers a wide range of conceptual, epistemological and methodological issues in the philosophy of science raised by reflection upon medical science and practice. Several chapters examine such general meta-scientific concepts as discovery, reduction, theories and models, causal inference and scientific realism as they apply to medicine or medical science in particular. Some discuss important concepts specific to medicine (diagnosis, health, disease, brain death). A topic such as evidence, for instance, is examined at a variety of levels, from social mechanisms for guiding evidence-based reasoning such as evidence-based medicine, consensus conferences, and clinical trials, to the more abstract analysis of experimentation, inference and uncertainty. Some chapters reflect on particular domains of medicine, including psychiatry, public health, and nursing. The contributions span a broad range of detailed cases from the science and practice of medicine, as well as a broad range of intellectual approaches, from conceptual analysis to detailed examinations of particular scientific papers or historical episodes. Chapters view philosophy of medicine from quite different angles Considers substantive cases from both medical science and practice Chapters from a distinguished array of contributors
Author : Michael Bresalier
Publisher : Springer Nature
ISBN 13 : 1137339543
Total Pages : 476 pages
Book Rating : 4.1/5 (373 download)
Download or read book Modern Flu written by Michael Bresalier and published by Springer Nature. This book was released on 2023-09-09 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ninety years after the discovery of human influenza virus, Modern Flu traces the history of this breakthrough and its implications for understanding and controlling influenza ever since. Examining how influenza came to be defined as a viral disease in the first half of the twentieth century, it argues that influenza’s viral identity did not suddenly appear with the discovery of the first human influenza virus in 1933. Instead, it was rooted in the development of medical virus research and virological ways of knowing that grew out of a half-century of changes and innovations in medical science that were shaped through two influenza pandemics, two world wars, and by state-sponsored programs to scientifically modernise British medicine. A series of transformations, in which virological ideas and practices were aligned with and incorporated into medicine and public health, underpinned the viralisation of influenza in the 1930s and 1940s. Collaboration, conflict and exchange between researchers, medical professionals and governmental bodies lay at the heart of this process. This book is a history of how virus researchers, clinicians, and epidemiologists, medical scientific and public health bodies, and institutions, and philanthropies in Britain, the USA and beyond, forged a new medical consensus on the identity and nature of influenza. Shedding new light on the modern history of influenza, this book is a timely account of how ways of knowing and controlling this intractable epidemic disease became viral.
Author : Kunal Kulkarni
Publisher : Oxford University Press
ISBN 13 : 0191059293
Total Pages : 890 pages
Book Rating : 4.1/5 (91 download)
Download or read book Oxford Handbook of Key Clinical Evidence written by Kunal Kulkarni and published by Oxford University Press. This book was released on 2016-10-20 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of the Oxford Handbook of Key Clinical Evidence provides an alternative to the growing volumes of trial data for students, trainees and researchers looking for the key evidence affecting medical practice. Written by a team of leading figures across the major specialities, the Oxford Handbook of Key Clinical Evidence carefully selects and brings together key information on some of the most important trials currently impacting clinical practice. With introductory chapters on the history and importance of evidence based medicine complemented by in-depth analysis of the impact of each trial and its practical implications, this text is a definitive quick-reference guide in this increasingly important field. Highlighted boxes identify the study type and evidence-level attained, while analysis of the key message and impacts of the trial firmly place the evidence into a practical setting for the reader. This extensively revised Handbook presents the key data, facts, and evidence informing both medical and surgical specialties. This second edition includes a brand new chapter on paediatrics. It incorporates new landmark trials which are changing clinical practice, and re-reviews previously included trials to ensure consistency with current practice. It is essential reading for everyone with an interest in getting to grasps with the fundamental evidence underpinning modern practice.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309095042
Total Pages : 431 pages
Book Rating : 4.3/5 (9 download)
Download or read book The Threat of Pandemic Influenza written by Institute of Medicine and published by National Academies Press. This book was released on 2005-04-09 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.
Author :
Publisher : Createspace Independent Pub
ISBN 13 : 9781508807438
Total Pages : 206 pages
Book Rating : 4.8/5 (74 download)
Download or read book "Ethically Impossible" written by and published by Createspace Independent Pub. This book was released on 2011 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to a request by President Barak Obama on November 24, 2010, the Presidential Commission for the Study of Bioethical Issues oversaw a thorough fact-finding investigation into the specifics of the U.S. Public Health Service-led studies in Guatemala involving the intentional exposure and infection of vulnerable populations. Following a nine-month intensive investigation, the Commission has concluded that the Guatemala experiments involved gross violations of ethics as judged against both the standards of today and the researchers' own understanding of applicable contemporaneous practices. It is the Commission's firm belief that many of the actions undertaken in Guatemala were especially egregious moral wrongs because many of the individuals involved held positions of public institutional responsibility. The best thing we can do as a country when faced with a dark chapter is to bring it to light. The Commission has worked hard to provide an unvarnished ethical analysis to both honor the victims and make sure events such as these never happen again.
Author : John Forrester
Publisher : Cambridge University Press
ISBN 13 : 1316849015
Total Pages : 719 pages
Book Rating : 4.3/5 (168 download)
Download or read book Freud in Cambridge written by John Forrester and published by Cambridge University Press. This book was released on 2017-03-09 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: Freud may never have set foot in Cambridge - that hub for the twentieth century's most influential thinkers and scientists - but his intellectual impact there in the years between the two World Wars was immense. This is a story that has long languished untold, buried under different accounts of the dissemination of psychoanalysis. John Forrester and Laura Cameron present a fascinating and deeply textured history of the ways in which a set of Freudian ideas about the workings of the human mind, sexuality and the unconscious affected Cambridge men and women - from A. G. Tansley and W. H. R. Rivers to Bertrand Russell, Bernal, Strachey and Wittgenstein - shaping their thinking across a range of disciplines, from biology to anthropology, and from philosophy to psychology, education and literature. Freud in Cambridge will be welcomed as a major intervention by literary scholars, historians and all readers interested in twentieth-century intellectual and scientific life.
Author : Redaktion Osnabrück
Publisher : de Gruyter
ISBN 13 : 9783110230253
Total Pages : 904 pages
Book Rating : 4.2/5 (32 download)
Download or read book 2010 written by Redaktion Osnabrück and published by de Gruyter. This book was released on 2011-06-16 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Timo Bolt
Publisher : Maklu
ISBN 13 : 9044132997
Total Pages : 468 pages
Book Rating : 4.0/5 (441 download)
Download or read book A doctor's order. The Dutch Case of Evidence-Based Medicine (1970-2015) written by Timo Bolt and published by Maklu. This book was released on 2015-08-28 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the early 1990s, a new concept was coined: ‘evidence-based medicine’ (EBM). After a remarkably short time, EBM was virtually all-pervasive in medicine and healthcare throughout the world. Even outside the domain of healthcare, the new concept became fashionable, for example in the shape of (pleas for) ‘evidence-based management’ and ‘evidence-based policy’. In short, ‘evidence-based’ developed into one of the mantras of the current era. This book uses history as a tool to gain insight into the highly influential, but also elusive and multifaceted phenomenon of EBM. As such, A Doctor’s Order is a ‘must read’ for patients, professionals, managers and policy makers in healthcare as well as for anyone who is interested in understanding the present socio-political order.
Author :
Publisher :
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.3/5 (91 download)
Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 2006 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tiago Moreira
Publisher : Routledge
ISBN 13 : 1136274251
Total Pages : 279 pages
Book Rating : 4.1/5 (362 download)
Download or read book The Transformation of Contemporary Health Care written by Tiago Moreira and published by Routledge. This book was released on 2013-05-07 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past three decades have seen enormous changes in the organisation of health care. This book explores the role of knowledge production and technology on these transformations, focusing on the market (attempts to embed principles of economic rationality and efficient use of resources in the shaping and delivery of health care), the laboratory (science, experiments and 'evidence' in the management of research, practice and policy) and the forum (the application of deliberative procedures and other forms of public consultation to health care decision making).
Author : Ezekiel J. Emanuel
Publisher : OUP USA
ISBN 13 : 0199768633
Total Pages : 848 pages
Book Rating : 4.1/5 (997 download)
Download or read book The Oxford Textbook of Clinical Research Ethics written by Ezekiel J. Emanuel and published by OUP USA. This book was released on 2011-02 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Textbook of Clinical Research Ethics is the first comprehensive and systematic reference on clinical research ethics. Under the editorship of experts from the U.S. National Institutes of Health of the United States, the book's 73 chapters offer a wide-ranging and systematic examination of all aspects of research with human beings. Considering the historical triumphs of research as well as its tragedies, the textbook provides a framework for analyzing the ethical aspects of research studies with human beings. Through both conceptual analysis and systematic reviews of empirical data, the contributors examine issues ranging from scientific validity, fair subject selection, risk benefit ratio, independent review, and informed consent to focused consideration of international research ethics, conflicts of interests, and other aspects of responsible conduct of research. The editors of The Oxford Textbook of Clinical Research Ethics offer a work that critically assesses and advances scholarship in the field of human subjects research. Comprehensive in scope and depth, this book will be a crucial resource for researchers in the medical sciences, as well as teachers and students.
Author : Joanna Baines
Publisher : Springer
ISBN 13 : 113735352X
Total Pages : 249 pages
Book Rating : 4.1/5 (373 download)
Download or read book The Changing Faces of Childhood Cancer written by Joanna Baines and published by Springer. This book was released on 2014-12-18 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book traces the development of British answers to the problem of childhood cancer. The establishment of the NHS and better training for paediatricians, meant children were given access to experimental chemotherapy, sending cure rates soaring. Children with cancer were thrust into the spotlight as individuals' stories of hope hit the headlines.
