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Author :
Publisher :
ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.3/5 (121 download)
Download or read book First Conference on DNA Topoisomerases in Cancer Chemotherapy written by and published by . This book was released on 1987 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book First Conference on DNA Topoisomerases in Cancer Chemotherapy written by and published by . This book was released on 1987 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Conference on DNA Topoisomerases in Cancer Chemotherapy
Publisher :
ISBN 13 :
Total Pages : 149 pages
Book Rating : 4.:/5 (256 download)
Download or read book First Conference on DNA Topoisomerases in Cancer Chemotherapy written by Conference on DNA Topoisomerases in Cancer Chemotherapy and published by . This book was released on 1987 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Milan Potmesil
Publisher :
ISBN 13 :
Total Pages : 149 pages
Book Rating : 4.:/5 (716 download)
Download or read book Conference on DNA Topoisomerases in Cancer Chemotherapy written by Milan Potmesil and published by . This book was released on 1987 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 149 pages
Book Rating : 4.:/5 (166 download)
Download or read book First Conference on DNA Topoisomerases in Cancer Chemotherapy written by and published by . This book was released on 1987 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Toshiwo Andoh
Publisher : CRC Press
ISBN 13 : 9780849349706
Total Pages : 400 pages
Book Rating : 4.3/5 (497 download)
Download or read book Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy written by Toshiwo Andoh and published by CRC Press. This book was released on 1992-10-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy is based on conference proceedings from the International Symposium on DNA Topoisomerases in Chemotherapy, held in Nagoya, Japan, in November 1991. The book opens with a discussion of the structural and functional properties of various types of DNA topoisomerases identified in prokaryotes and eukaryotes, in addition to their roles as cellular targets of anticancer and antimicrobial agents. Other topics addressed include the genetics and biology of DNA topoisomerases, inhibitors of microbial DNA topoisomerases and drug resistance, inhibitors of mammalian DNA topoisomerases and drug resistance, and preclinical and clinical studies of DNA topoisomerase inhibitors. Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy will broaden the understanding of biology and genetics of DNA topoisomerases and contribute to the development of antimicrobial and anticancer agents-inhibitors of topoisomerases. It will be invaluable for oncologists, molecular biologists, cellular biologists, geneticists, biochemists, and pharmaceutical researchers.
Author : Yves Pommier
Publisher : Springer Science & Business Media
ISBN 13 : 1461403235
Total Pages : 443 pages
Book Rating : 4.4/5 (614 download)
Download or read book DNA Topoisomerases and Cancer written by Yves Pommier and published by Springer Science & Business Media. This book was released on 2011-09-21 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action.
Author : Milan Potmesil
Publisher :
ISBN 13 :
Total Pages : 149 pages
Book Rating : 4.:/5 (159 download)
Download or read book First Conference on DNA Topoisomerases in Cancer Chemotherapy written by Milan Potmesil and published by . This book was released on 1987 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Toshiwo Andoh
Publisher : Springer Science & Business Media
ISBN 13 : 1461501415
Total Pages : 208 pages
Book Rating : 4.4/5 (615 download)
Download or read book DNA Topoisomerases in Cancer Therapy written by Toshiwo Andoh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University. Readers will find a series of chapters written by researchers actively engaged in the expanding field of topoisomerase and their inhibitors. The series of chapters cover review articles on pharmacology and the molecular mechanism of topoisomerase I- and II-targeting anticancer drugs in mammals and in the yeast Saccharomyces cerevisiae, which has proved to be a superb model organism for studies of anticancer drugs. This volume compiles up-to-date information on the topoisomerase-targeting compounds in clinical and preclinical development as a useful and important reference book for students and researchers in the field of pharmacology, toxicology, oncology and molecular biology.
Author :
Publisher :
ISBN 13 : 9781461403241
Total Pages : 456 pages
Book Rating : 4.4/5 (32 download)
Download or read book DNA Topoisomerases and Cancer written by and published by . This book was released on 2011-09-21 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : New York University. Medical Center
Publisher :
ISBN 13 :
Total Pages : 53 pages
Book Rating : 4.:/5 (478 download)
Download or read book The Fifth Conference on DNA Topoisomerases in Therapy written by New York University. Medical Center and published by . This book was released on 1994 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Milan Potmesil
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.3/5 (91 download)
Download or read book DNA Topoisomerases in Cancer written by Milan Potmesil and published by Oxford University Press, USA. This book was released on 1991 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Topoisomerases are a unique class of enzymes that are responsible for the control and modification of DNA topology (tertiary structure); one example of their function is the transformation of chromosomes from a supercoiled condensed state to uncoiled strands and vice versa. They are of interest both for their intrinsic role in cell biology (i.e. control of cell division) and also because some anticancer drugs, such as camptothecin, act by inhibiting their action.
Author :
Publisher :
ISBN 13 :
Total Pages : 127 pages
Book Rating : 4.:/5 (16 download)
Download or read book ˜Theœ Sixth Conference on DNA Topoisomerases in Therapy written by and published by . This book was released on 1995 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Milan Potmesil
Publisher :
ISBN 13 :
Total Pages : 149 pages
Book Rating : 4.:/5 (64 download)
Download or read book DNA Topoisomerases in Cancer Chemotherapy written by Milan Potmesil and published by . This book was released on 1987 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stella Margaret Davies
Publisher :
ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.:/5 (24 download)
Download or read book DNA Topoisomerases in Cancer Chemotherapy written by Stella Margaret Davies and published by . This book was released on 1989 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.:/5 (319 download)
Download or read book NCI Monographs written by and published by . This book was released on 1987 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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ISBN 13 :
Total Pages : 1074 pages
Book Rating : 4.E/5 ( download)
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1996 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt:
