Conceptual Background And Bioenergetic Mitochondrial Aspects Of Oncometabolism

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Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism

Author :
Publisher : Elsevier
ISBN 13 : 0124166571
Total Pages : 565 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism by :

Download or read book Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism written by and published by Elsevier. This book was released on 2014-05-23 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in biomineralization science - Provides theoretical overview on metabolic alterations of cancer cells, and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo

Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism

Author : Guido Kroemer
Publisher :
ISBN 13 :
Total Pages : 509 pages
Book Rating : 4.:/5 (11 download)

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Book Synopsis Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism by : Guido Kroemer

Download or read book Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism written by Guido Kroemer and published by . This book was released on 2014 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cell-wide Metabolic Alterations Associated with Malignancy

Author :
Publisher : Academic Press
ISBN 13 : 0128014830
Total Pages : 403 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Cell-wide Metabolic Alterations Associated with Malignancy by :

Download or read book Cell-wide Metabolic Alterations Associated with Malignancy written by and published by Academic Press. This book was released on 2014-06-07 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in biomineralization science - Contains sections on such topics providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo.

Natural Products and Brain Energy Metabolism: Astrocytes in Neurodegenerative Diseases, Volume I

Author : Fushun Wang
Publisher : Frontiers Media SA
ISBN 13 : 2832505201
Total Pages : 202 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Natural Products and Brain Energy Metabolism: Astrocytes in Neurodegenerative Diseases, Volume I by : Fushun Wang

Download or read book Natural Products and Brain Energy Metabolism: Astrocytes in Neurodegenerative Diseases, Volume I written by Fushun Wang and published by Frontiers Media SA. This book was released on 2022-11-11 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Plant Metal Interaction

Author : Parvaiz Ahmad
Publisher : Elsevier
ISBN 13 : 0128031832
Total Pages : 654 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Plant Metal Interaction by : Parvaiz Ahmad

Download or read book Plant Metal Interaction written by Parvaiz Ahmad and published by Elsevier. This book was released on 2016-02-02 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Metal Interaction: Emerging Remediation Techniques covers different heavy metals and their effect on soils and plants, along with the remediation techniques currently available. As cultivable land is declining day-by-day as a result of increased metals in our soil and water, there is an urgent need to remediate these effects. This multi-contributed book is divided into four sections covering the whole of plant metal interactions, including heavy metals, approaches to alleviate heavy metal stress, microbial approaches to remove heavy metals, and phytoremediation. - Provides an overview of the effect of different heavy metals on growth, biochemical reactions, and physiology of various plants - Serves as a reference guide for available techniques, challenges, and possible solutions in heavy metal remediation - Covers sustainable technologies in uptake and removal of heavy metals

Translational Endocrinology of Bone

Author : Gerard Karsenty
Publisher : Academic Press
ISBN 13 : 0124158595
Total Pages : 247 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Translational Endocrinology of Bone by : Gerard Karsenty

Download or read book Translational Endocrinology of Bone written by Gerard Karsenty and published by Academic Press. This book was released on 2012-12-31 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of model organisms together with the power of genetics has profoundly affected our understanding of the physiology of one organ, the skeleton, in two distinct but complementary ways. This is the first translational reference to focus on these major conceptual advances in bone biology and their development in the clinic. Several advances have already been translated into therapies and others are being tested for diseases as different as osteoporosis, type-2 diabetes, and hypo-fertility. This book is a timely reference for both basic and clinical researchers in bone biology and endocrinology. - Summarizes the latest research and translational applications of how the varied growth and development of bone affects appetite, metabolism, reproduction, and a wide range of endocrine functions - Provides a common language for bone biologists, endocrinologists, osteologists, and other researchers, such as neuroscientists, who study appetite, fuel metabolism and diabetes, to discuss the development of translational research and new therapeutic strategies for bone, metabolic, and neuro-endocrine diseases - Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of bone research and therapeutics, as opposed to searching through thousands of journal articles

Nanomaterials in Plants, Algae and Microorganisms

Author : Durgesh Kumar Tripathi
Publisher : Academic Press
ISBN 13 : 0128116455
Total Pages : 388 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanomaterials in Plants, Algae and Microorganisms by : Durgesh Kumar Tripathi

Download or read book Nanomaterials in Plants, Algae and Microorganisms written by Durgesh Kumar Tripathi and published by Academic Press. This book was released on 2018-09-14 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials in Plants, Algae and Microorganisms: Concepts and Controversies: Volume 2 not only covers all the new technologies used in the synthesis of nanoparticles, it also tests their response on plants, algae and micro-organisms in aquatic ecosystems. Unlike most works in the field, the book doesn't focus exclusively on the higher organisms. Instead, it explores the smaller life forms on which they feed. Topics include the impacts of plant development, how different nanoparticles are absorbed by biota, the impact different metals—including silver and rare earth metals—have on living organisms, and the effects nanoparticles have on aquatic ecosystems as a whole. As nanotechnology based products have become a trillion-dollar industry, there is a need to understand the implications to the health of our biota and ecosystems as the earth is increasingly inundated with these materials. - Covers the issues of nanoparticles on more simple organisms and their ecosystems - Draws upon global experts to help increase understanding of the interface mechanisms at the physiological, biochemical, molecular, and even genomic and proteomic level between ENPs and biological systems - Provides a critical assessment of the progress taking place on this topic - Sheds light on future research needs and scientific challenges that still exist in nanoparticle and living organism interactions

Medicinal Chemistry of Anticancer Drugs

Author : Carmen Avendaño
Publisher : Elsevier
ISBN 13 : 0444626670
Total Pages : 767 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Medicinal Chemistry of Anticancer Drugs by : Carmen Avendaño

Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. - Presents information in a clear and concise way using a large number of figures - Historical background provides insights on how the process of drug discovery in the anticancer field has evolved - Extensive references to primary literature

Biomarkers in Marine Organisms

Author : Ph. Garrigues
Publisher : Elsevier
ISBN 13 : 008052804X
Total Pages : 573 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Biomarkers in Marine Organisms by : Ph. Garrigues

Download or read book Biomarkers in Marine Organisms written by Ph. Garrigues and published by Elsevier. This book was released on 2001-11-07 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many previous studies and books have been dedicated to fundamental and developmental aspects of biomarkers. The purpose of this book is to provide, through various case studies, an overview of the practical use of biological markers in marine animals to evaluate the health effects of environmental contamination in marine ecosystems. More precisely, the book presents the results obtained during the development and application of biological markers as indicators of exposure/effect to toxic chemicals in marine environments, using diverse sentinel species such as fish, bivalves and crustaceans. An important aspect is also the publication of technical annexes that describe in detail the experimental procedures developed for both chemical and biochemical measurement.

Comprehensive Toxicology

Author :
Publisher : Elsevier
ISBN 13 : 0080468845
Total Pages : 6448 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Comprehensive Toxicology by :

Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2010-06-01 with total page 6448 pages. Available in PDF, EPUB and Kindle. Book excerpt: An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version

Methods in Systems Biology

Author : Daniel Jameson
Publisher : Academic Press
ISBN 13 : 0123851181
Total Pages : 775 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Methods in Systems Biology by : Daniel Jameson

Download or read book Methods in Systems Biology written by Daniel Jameson and published by Academic Press. This book was released on 2011-09-26 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems biology is a term used to describe a number of trends in bioscience research and a movement that draws on those trends. This volume in the Methods in Enzymology series comprehensively covers the methods in systems biology. With an international board of authors, this volume is split into sections that cover subjects such as machines for systems biology, protein production and quantification for systems biology, and enzymatic assays in systems biology research. This volume in the Methods in Enzymology series comprehensively covers the methods in systems biology With an international board of authors, this volume is split into sections that cover subjects such as machines for systems biology, protein production and quantification for systems biology, and enzymatic assays in systems biology research

Inter-Organellar Ca2+ Signaling in Health and Disease - Part B

Author :
Publisher : Academic Press
ISBN 13 : 0128240377
Total Pages : 288 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Inter-Organellar Ca2+ Signaling in Health and Disease - Part B by :

Download or read book Inter-Organellar Ca2+ Signaling in Health and Disease - Part B written by and published by Academic Press. This book was released on 2021-08-12 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology. - Publishes only invited review articles on selected topics - Authored by established and active cell and molecular biologists and drawn from international sources - Offers a wide range of perspectives on specific subjects

3D Bioprinting for Reconstructive Surgery

Author : Daniel J. Thomas
Publisher : Woodhead Publishing
ISBN 13 : 0081012160
Total Pages : 452 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis 3D Bioprinting for Reconstructive Surgery by : Daniel J. Thomas

Download or read book 3D Bioprinting for Reconstructive Surgery written by Daniel J. Thomas and published by Woodhead Publishing. This book was released on 2017-11-14 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field. - Discusses new possibilities in tissue engineering with 3D printing - Presents a comprehensive coverage of the materials, techniques and tools needed for producing bioprinted tissues - Reviews emerging technologies in addition to commercial techniques

Nutritional Epigenomics

Author :
Publisher : Elsevier
ISBN 13 : 0443155739
Total Pages : 0 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Nutritional Epigenomics by :

Download or read book Nutritional Epigenomics written by and published by Elsevier. This book was released on 2025-03-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutritional Epigenomics, Second Edition, a volume in the Translational Epigenetics, offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health, and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. This new edition has been fully updated to reflect current research in the field. All-new and revised chapters consider the social and physical environments associated with DNA methylation, the relationship between nutritional epigenomics and inflammation, chromatin modifications and non-coding RNAs, as well as the epigenetic influence of food bioactives in metabolic disease and cancer, empowering researchers to employ nutritional epigenomics approaches in new, field-driving studies and applications. - Empowers researchers and clinicians to employ nutritional epigenomics approaches in their own research and practice - Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies - Concludes with clinical recommendations and practical applications related to nutrition and lifestyle choices - Fully considers recent advances in the field, including new research into chromatin modifications, non-coding RNAs, and fiber regulation of the microbiome and human health - Features chapter contributions from international leaders in the field

Hydrogen Peroxide and Cell Signaling, Part B

Author :
Publisher : Academic Press
ISBN 13 : 9780124058828
Total Pages : 0 pages
Book Rating : 4.0/5 (588 download)

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Book Synopsis Hydrogen Peroxide and Cell Signaling, Part B by :

Download or read book Hydrogen Peroxide and Cell Signaling, Part B written by and published by Academic Press. This book was released on 2013-07-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the second of three volumes on hydrogen peroxide and cell signaling, and includes chapters on such topics as the cellular steady-state of H2O2, evaluating peroxiredoxin sensitivity towards inactivation by peroxide substrates, and peroxiredoxins as preferential targets in H2O2-induced signaling.

Chemistry of Plant Phosphorus Compounds

Author : Arlen Frank
Publisher : Elsevier
ISBN 13 : 0124072232
Total Pages : 688 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Chemistry of Plant Phosphorus Compounds by : Arlen Frank

Download or read book Chemistry of Plant Phosphorus Compounds written by Arlen Frank and published by Elsevier. This book was released on 2013-06-03 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a high level reference source for scientists engaged in any aspect of plant research - chemistry, biochemistry or physiology - with primary focus on the chemistry of phosphorus-containing compounds that occur naturally in the plant kingdom, and specifically in the higher plants (Plantae). The book is comprehensive with respect to nomenclature, physical properties, and distribution worldwide. There are many tables of actual data on phosphorus compounds occurring in whole plants and parts of plants. The tables provide detailed data that is needed by the food industry, agriculture, etc as many of the phosphorus compounds are common to both plants and animals. Two appendices cover other aspects including changes in phosphorus-containing compounds during germination and their accumulation during growth and senescence. The final sections of the book comprise separate indexes of plants, compounds and authors. - Comprehensive examination of phosphorus compounds found in plants - Extensive tables listing types of compounds and their occurrence in plants including: Nomenclature; Occurrence; Physical Properties; Synthesis; Hydrolysis; Phosphorylation; Extraction; Separation and Analysis - Easy to use indexes of plants, compounds and authors

Vitamins and the Immune System

Author :
Publisher : Academic Press
ISBN 13 : 0123869617
Total Pages : 503 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Vitamins and the Immune System by :

Download or read book Vitamins and the Immune System written by and published by Academic Press. This book was released on 2011-05-09 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on vitamins and the immune system. - Longest running series published by Academic Press - Contributions by leading international authorities