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Author : Russell F. Doolittle
Publisher :
ISBN 13 : 9780121812676
Total Pages : 711 pages
Book Rating : 4.8/5 (126 download)
Download or read book Computer Methods for Macromolecular Sequence Analysis written by Russell F. Doolittle and published by . This book was released on 1996 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 9780121821678
Total Pages : 711 pages
Book Rating : 4.8/5 (216 download)
Download or read book Computer Methods for Macromolecular Sequence Analysis written by and published by Academic Press. This book was released on 1996-06-06 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 260 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * Databases and resources * Searching through databases * Multiple alignment and phylogenetic trees * Secondary structure considerations * Three-dimensional considerations
Author : Annette M. Griffin
Publisher : Springer Science & Business Media
ISBN 13 : 1592595111
Total Pages : 370 pages
Book Rating : 4.5/5 (925 download)
Download or read book Computer Analysis of Sequence Data, Part I written by Annette M. Griffin and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gen- ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods ess- tial to analysis, and a familiarity with computers and sequence ana- sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Analysis of Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or p- tein) sequences. Each chapter is written such that a competent sci- tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed pr- tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes enco- tered by users of the sequence analysis software. Software packages for both the mainframe and personal computers are described.
Author : Arthur M. Lesk
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.:/5 (45 download)
Download or read book Computational Molecular Biology written by Arthur M. Lesk and published by Oxford University Press, USA. This book was released on 1988 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the field of computing with protein and nucleic acid sequences, aimed at investigators determining sequences, those who analyze them to identify unknown proteins and interpret their function, and those interested in the three-dimensional structures of biological molecules.
Author : Annette M. Griffin
Publisher : Springer Science & Business Media
ISBN 13 : 159259512X
Total Pages : 434 pages
Book Rating : 4.5/5 (925 download)
Download or read book Computer Analysis of Sequence Data Part II written by Annette M. Griffin and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gener ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods essen tial to analysis, and a familiarity with computers and sequence analy sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Computer Analysis of Sequence Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or pro tein) sequences. Each chapter is written such that a competent scien tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed prac tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes encoun tered by users of the sequence analysis software.
Author : Tieng K. Yap
Publisher : Springer Science & Business Media
ISBN 13 : 1461313910
Total Pages : 219 pages
Book Rating : 4.4/5 (613 download)
Download or read book High Performance Computational Methods for Biological Sequence Analysis written by Tieng K. Yap and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: High Performance Computational Methods for Biological Sequence Analysis presents biological sequence analysis using an interdisciplinary approach that integrates biological, mathematical and computational concepts. These concepts are presented so that computer scientists and biomedical scientists can obtain the necessary background for developing better algorithms and applying parallel computational methods. This book will enable both groups to develop the depth of knowledge needed to work in this interdisciplinary field. This work focuses on high performance computational approaches that are used to perform computationally intensive biological sequence analysis tasks: pairwise sequence comparison, multiple sequence alignment, and sequence similarity searching in large databases. These computational methods are becoming increasingly important to the molecular biology community allowing researchers to explore the increasingly large amounts of sequence data generated by the Human Genome Project and other related biological projects. The approaches presented by the authors are state-of-the-art and show how to reduce analysis times significantly, sometimes from days to minutes. High Performance Computational Methods for Biological Sequence Analysis is tremendously important to biomedical science students and researchers who are interested in applying sequence analyses to their studies, and to computational science students and researchers who are interested in applying new computational approaches to biological sequence analyses.
Author : Russell F. Doolittle
Publisher : Academic Press
ISBN 13 :
Total Pages : 760 pages
Book Rating : 4.X/5 (2 download)
Download or read book Computer Methods for Macromolecular Sequence Analysis written by Russell F. Doolittle and published by Academic Press. This book was released on 1996-05-23 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume supplements Volume 183 in the "Methods in Enyzmology" series and complements Volume 224. It addresses a variety of areas in which computers are used to manage and manipulate macromolecular sequence data. The manipulations include searching, aligning and determining the significance of similarities as well as the construction of phylogenetic trees that show evolutionary history of related sequences
Author : N A Kolchanov
Publisher : World Scientific
ISBN 13 : 9814504270
Total Pages : 580 pages
Book Rating : 4.8/5 (145 download)
Download or read book Computer Analysis of Genetic Macromolecules: Structure, Function and Evolution written by N A Kolchanov and published by World Scientific. This book was released on 1994-03-29 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology and genetics are fast-growing fields with significant results and findings being reported virtually every day. Raw data from the wet lab accumulate at an astonishing rate, making it necessary to analyze the biological data with the use of computers. This book reveals how the current challenges of molecular biology and genetics are met with computer and mathematical treatments. A combined effort of the Computational Genetics and Biophysics Group (Supercomputer Computations Research Institute, USA), the Theoretical Molecular Genetics (Russian Academy of Sciences, Russia) and the Bioinformatics Group (Consiglio Nazionale delle Ricerche, Italy), many of these findings are firsthand discoveries made by these groups. The book emphasizes the fundamental principles of the structural-functional organization of the 3 major classes of genetic macromolecules: DNA, RNA and proteins. It also introduces universally applicable theoretical principles into the enormous realm of raw data and develops an integrative, theoretical computer approach to the analysis of these macromolecules to gain insights into the complexities of their function and evolution. Contents:Computer Analysis of Structural-Functional Organization of Nucleotide SequencesMobile Genetic Elements and Transposable Sequences: Principles of Structural-Functional Organization and EvolutionComputer Investigation of Molecular Mechanisms of MutagenesisInvestigation of Protein Structural-Functional Organization and EvolutionGenetic Macro-molecules: Principles and Mechanisms of Evolution Readership: Biochemists, computational scientists, geneticists, mathematicians and molecular biologists. keywords:Computer Analysis;Genetic Macromolecules;Evolution;DNA;RNA;Proteins;Bioinformatics;DNA/RNA Atructure;Gene Expression
Author : Sarah Barron
Publisher : DIANE Publishing
ISBN 13 : 9780941375917
Total Pages : 120 pages
Book Rating : 4.3/5 (759 download)
Download or read book A Bibliography on Computational Molecular Biology and Genetics written by Sarah Barron and published by DIANE Publishing. This book was released on 1991 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive bibliographic review of the literature related to DNA mapping and sequence analysis, with a focus on computer and mathematical aspects of molecular biology and genetics. Over 2200 entries, arranged by author's name.
Author : S.L. Salzberg
Publisher : Elsevier
ISBN 13 : 0080860931
Total Pages : 399 pages
Book Rating : 4.0/5 (88 download)
Download or read book Computational Methods in Molecular Biology written by S.L. Salzberg and published by Elsevier. This book was released on 1998-06-19 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational biology is a rapidly expanding field, and the number and variety of computational methods used for DNA and protein sequence analysis is growing every day. These algorithms are extremely valuable to biotechnology companies and to researchers and teachers in universities. This book explains the latest computer technology for analyzing DNA, RNA, and protein sequences. Clear and easy to follow, designed specifically for the non-computer scientist, it will help biologists make better choices on which algorithm to use. New techniques and demonstrations are elucidated, as are state-of-the-art problems, and more advanced material on the latest algorithms. The primary audience for this volume are molecular biologists working either in biotechnology companies or academic research environments, individual researchers and the institutions they work for, and students. Any biologist who relies on computers should want this book. A secondary audience will be computer scientists developing techniques with applications in biology. An excellent reference for leading techniques, it will also help introduce computer scientists to the biology problems. This is an outstanding work which will be ideal for the increasing number of scientists moving into computational biology.
Author : Gunnar Von Heijne
Publisher : Elsevier
ISBN 13 : 032316028X
Total Pages : 203 pages
Book Rating : 4.3/5 (231 download)
Download or read book Sequence Analysis in Molecular Biology written by Gunnar Von Heijne and published by Elsevier. This book was released on 2012-12-02 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence Analysis in Molecular Biology: Treasure Trove or Trivial Pursuit presents the methods for sequence analysis of DNA and proteins. This book contains eight chapters that consider the sequence analysis either directly on a microcomputer or using one of the main sequence/programs data banks. This book starts with a description of the main nucleic acid and protein sequence data banks, followed by a short section on the ""housekeeping aids"" that the computer can provide during a sequencing project. Chapters 4 and 5 deal with nucleic acid and protein sequence analysis. Chapter 6 treats algorithms for homology searching and sequence alignments. Chapter 7 presents some selected examples of how computer modeling can help decide whether an observed sequence pattern is significant or not, and how computer simulation is sometimes used to get a feeling for the behavior of intrinsically complex sequence-dependent processes. Chapter 8 contains some comments on the role of theoretical sequence analysis in molecular biology. This book is directed toward molecular biologists.
Author :
Publisher : Elsevier
ISBN 13 : 0080497225
Total Pages : 313 pages
Book Rating : 4.0/5 (84 download)
Download or read book Numerical Computer Methods, Part E written by and published by Elsevier. This book was released on 2004-06-02 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributions in this volume emphasize analysis of experimental data and analytical biochemistry, with examples taken from biochemistry. They serve to inform biomedical researchers of the modern data analysis methods that have developed concomitantly with computer hardware. Selected Contents: A practical approach to interpretation of SVD results; modeling of oscillations in endocrine networks with feedback; quantifying asynchronous breathing; sample entropy; wavelet modeling and processing of nasal airflow traces
Author :
Publisher : Elsevier
ISBN 13 : 0080497217
Total Pages : 527 pages
Book Rating : 4.0/5 (84 download)
Download or read book Numerical Computer Methods, Part D written by and published by Elsevier. This book was released on 2004-05-25 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of Numerical Computer Methods, Part D is to brief researchers of the importance of data analysis in enzymology, and of the modern methods that have developed concomitantly with computer hardware. It is also to validate researchers' computer programs with real and synthetic data to ascertain that the results produced are what they expected. Selected Contents: Prediction of protein structure Modeling and studying proteins with molecular dynamics Statistical error in isothermal titration calorimetry Analysis of circular dichroism data Model comparison methods
Author : Ronald Reid
Publisher : CRC Press
ISBN 13 : 9781420001334
Total Pages : 918 pages
Book Rating : 4.0/5 (13 download)
Download or read book Peptide and Protein Drug Analysis written by Ronald Reid and published by CRC Press. This book was released on 1999-11-12 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design. Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication. Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry demonstrates uses of unnatural mutagenesis and combinatorial chemistry explores mass spectrometry, protein sequence, and carbohydrate analysis illustrates bioassays and other new functional analysis methods surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR) addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering and more! Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemists; cell and molecular biologists; biochemists; and upper-level undergraduate and graduate students in these disciplines.
Author :
Publisher : Academic Press
ISBN 13 : 0080923291
Total Pages : 488 pages
Book Rating : 4.0/5 (89 download)
Download or read book Computer Methods written by and published by Academic Press. This book was released on 2009-03-10 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with previous and forthcoming 'Computer Methods' volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research.
Author :
Publisher : Academic Press
ISBN 13 : 0080962807
Total Pages : 711 pages
Book Rating : 4.0/5 (89 download)
Download or read book Computer Methods Part B written by and published by Academic Press. This book was released on 2009-11-05 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with previous and forthcoming Computer Methods volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research. Presents step-by-step computer methods and discusses the techniques in detail to enable their implementation in solving a wide range of problems Informs biomedical researchers of the modern data analysis methods that have developed alongside computer hardware Presents methods at the "nuts and bolts" level to identify and resolve a problem and analyze what the results mean
Author :
Publisher : Academic Press
ISBN 13 : 9780123812711
Total Pages : 696 pages
Book Rating : 4.8/5 (127 download)
Download or read book Computer Methods written by and published by Academic Press. This book was released on 2010-12-24 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with the 2 previous Computer Methods volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research. Presents step-by-step computer methods and discusses the techniques in detail to enable their implementation in solving a wide range of problems Informs biomedical researchers of the modern data analysis methods that have developed alongside computer hardware Presents methods at the "nuts and bolts" level to identify and resolve a problem and analyze what the results mean
