Computational and Methodological Statistics and Biostatistics

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Publisher : Springer Nature
ISBN 13 : 3030421961
Total Pages : 543 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Computational and Methodological Statistics and Biostatistics by : Andriëtte Bekker

Download or read book Computational and Methodological Statistics and Biostatistics written by Andriëtte Bekker and published by Springer Nature. This book was released on 2020-08-10 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the statistical domain, certain topics have received considerable attention during the last decade or so, necessitated by the growth and evolution of data and theoretical challenges. This growth has invariably been accompanied by computational advancement, which has presented end users as well as researchers with the necessary opportunities to handle data and implement modelling solutions for statistical purposes. Showcasing the interplay among a variety of disciplines, this book offers pioneering theoretical and applied solutions to practice-oriented problems. As a carefully curated collection of prominent international thought leaders, it fosters collaboration between statisticians and biostatisticians and provides an array of thought processes and tools to its readers. The book thereby creates an understanding and appreciation of recent developments as well as an implementation of these contributions within the broader framework of both academia and industry. Computational and Methodological Statistics and Biostatistics is composed of three main themes: • Recent developments in theory and applications of statistical distributions;• Recent developments in supervised and unsupervised modelling;• Recent developments in biostatistics; and also features programming code and accompanying algorithms to enable readers to replicate and implement methodologies. Therefore, this monograph provides a concise point of reference for a variety of current trends and topics within the statistical domain. With interdisciplinary appeal, it will be useful to researchers, graduate students, and practitioners in statistics, biostatistics, clinical methodology, geology, data science, and actuarial science, amongst others.

Statistics in the Health Sciences

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Publisher : CRC Press
ISBN 13 : 1315293757
Total Pages : 355 pages
Book Rating : 4.3/5 (152 download)

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Book Synopsis Statistics in the Health Sciences by : Albert Vexler

Download or read book Statistics in the Health Sciences written by Albert Vexler and published by CRC Press. This book was released on 2018-01-19 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This very informative book introduces classical and novel statistical methods that can be used by theoretical and applied biostatisticians to develop efficient solutions for real-world problems encountered in clinical trials and epidemiological studies. The authors provide a detailed discussion of methodological and applied issues in parametric, semi-parametric and nonparametric approaches, including computationally extensive data-driven techniques, such as empirical likelihood, sequential procedures, and bootstrap methods. Many of these techniques are implemented using popular software such as R and SAS."— Vlad Dragalin, Professor, Johnson and Johnson, Spring House, PA "It is always a pleasure to come across a new book that covers nearly all facets of a branch of science one thought was so broad, so diverse, and so dynamic that no single book could possibly hope to capture all of the fundamentals as well as directions of the field. The topics within the book’s purview—fundamentals of measure-theoretic probability; parametric and non-parametric statistical inference; central limit theorems; basics of martingale theory; Monte Carlo methods; sequential analysis; sequential change-point detection—are all covered with inspiring clarity and precision. The authors are also very thorough and avail themselves of the most recent scholarship. They provide a detailed account of the state of the art, and bring together results that were previously scattered across disparate disciplines. This makes the book more than just a textbook: it is a panoramic companion to the field of Biostatistics. The book is self-contained, and the concise but careful exposition of material makes it accessible to a wide audience. This is appealing to graduate students interested in getting into the field, and also to professors looking to design a course on the subject." — Aleksey S. Polunchenko, Department of Mathematical Sciences, State University of New York at Binghamton This book should be appropriate for use both as a text and as a reference. This book delivers a "ready-to-go" well-structured product to be employed in developing advanced courses. In this book the readers can find classical and new theoretical methods, open problems and new procedures. The book presents biostatistical results that are novel to the current set of books on the market and results that are even new with respect to the modern scientific literature. Several of these results can be found only in this book.

Advances in Complex Data Modeling and Computational Methods in Statistics

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Publisher : Springer
ISBN 13 : 3319111493
Total Pages : 210 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Advances in Complex Data Modeling and Computational Methods in Statistics by : Anna Maria Paganoni

Download or read book Advances in Complex Data Modeling and Computational Methods in Statistics written by Anna Maria Paganoni and published by Springer. This book was released on 2014-11-04 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is addressed to statisticians working at the forefront of the statistical analysis of complex and high dimensional data and offers a wide variety of statistical models, computer intensive methods and applications: network inference from the analysis of high dimensional data; new developments for bootstrapping complex data; regression analysis for measuring the downsize reputational risk; statistical methods for research on the human genome dynamics; inference in non-euclidean settings and for shape data; Bayesian methods for reliability and the analysis of complex data; methodological issues in using administrative data for clinical and epidemiological research; regression models with differential regularization; geostatistical methods for mobility analysis through mobile phone data exploration. This volume is the result of a careful selection among the contributions presented at the conference "S.Co.2013: Complex data modeling and computationally intensive methods for estimation and prediction" held at the Politecnico di Milano, 2013. All the papers published here have been rigorously peer-reviewed.

Marginal Models in Analysis of Correlated Binary Data with Time Dependent Covariates

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Publisher : Springer Nature
ISBN 13 : 3030489043
Total Pages : 182 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Marginal Models in Analysis of Correlated Binary Data with Time Dependent Covariates by : Jeffrey R. Wilson

Download or read book Marginal Models in Analysis of Correlated Binary Data with Time Dependent Covariates written by Jeffrey R. Wilson and published by Springer Nature. This book was released on 2020-09-28 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph provides a concise point of research topics and reference for modeling correlated response data with time-dependent covariates, and longitudinal data for the analysis of population-averaged models, highlighting methods by a variety of pioneering scholars. While the models presented in the volume are applied to health and health-related data, they can be used to analyze any kind of data that contain covariates that change over time. The included data are analyzed with the use of both R and SAS, and the data and computing programs are provided to readers so that they can replicate and implement covered methods. It is an excellent resource for scholars of both computational and methodological statistics and biostatistics, particularly in the applied areas of health. ​

Computational Intelligence Methods for Bioinformatics and Biostatistics

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Publisher : Springer
ISBN 13 : 3319678345
Total Pages : 268 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Computational Intelligence Methods for Bioinformatics and Biostatistics by : Andrea Bracciali

Download or read book Computational Intelligence Methods for Bioinformatics and Biostatistics written by Andrea Bracciali and published by Springer. This book was released on 2017-10-14 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the 13th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2016, held in Stirling, UK, in September 2016. The 19 revised full papers and 6 keynotes abstracts presented were carefully reviewed and selected from 61 submissions. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medicalinformatics, computational approaches to life sciences in general

Computational Methods in Biomedical Research

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Publisher : CRC Press
ISBN 13 : 9781420010923
Total Pages : 432 pages
Book Rating : 4.0/5 (19 download)

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Book Synopsis Computational Methods in Biomedical Research by : Ravindra Khattree

Download or read book Computational Methods in Biomedical Research written by Ravindra Khattree and published by CRC Press. This book was released on 2007-12-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing advances in biomedical research and statistical methods call for a constant stream of updated, cohesive accounts of new developments so that the methodologies can be properly implemented in the biomedical field. Responding to this need, Computational Methods in Biomedical Research explores important current and emerging computational statistical methods that are used in biomedical research. Written by active researchers in the field, this authoritative collection covers a wide range of topics. It introduces each topic at a basic level, before moving on to more advanced discussions of applications. The book begins with microarray data analysis, machine learning techniques, and mass spectrometry-based protein profiling. It then uses state space models to predict US cancer mortality rates and provides an overview of the application of multistate models in analyzing multiple failure times. The book also describes various Bayesian techniques, the sequential monitoring of randomization tests, mixed-effects models, and the classification rules for repeated measures data. The volume concludes with estimation methods for analyzing longitudinal data. Supplying the knowledge necessary to perform sophisticated statistical analyses, this reference is a must-have for anyone involved in advanced biomedical and pharmaceutical research. It will help in the quest to identify potential new drugs for the treatment of a variety of diseases.

Handbook of Computational Statistics

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Publisher : Springer
ISBN 13 : 9783662517659
Total Pages : 0 pages
Book Rating : 4.5/5 (176 download)

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Book Synopsis Handbook of Computational Statistics by : James E. Gentle

Download or read book Handbook of Computational Statistics written by James E. Gentle and published by Springer. This book was released on 2017-05-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Computational Statistics - Concepts and Methods (second edition) is a revision of the first edition published in 2004, and contains additional comments and updated information on the existing chapters, as well as three new chapters addressing recent work in the field of computational statistics. This new edition is divided into 4 parts in the same way as the first edition. It begins with "How Computational Statistics became the backbone of modern data science" (Ch.1): an overview of the field of Computational Statistics, how it emerged as a separate discipline, and how its own development mirrored that of hardware and software, including a discussion of current active research. The second part (Chs. 2 - 15) presents several topics in the supporting field of statistical computing. Emphasis is placed on the need for fast and accurate numerical algorithms, and some of the basic methodologies for transformation, database handling, high-dimensional data and graphics treatment are discussed. The third part (Chs. 16 - 33) focuses on statistical methodology. Special attention is given to smoothing, iterative procedures, simulation and visualization of multivariate data. Lastly, a set of selected applications (Chs. 34 - 38) like Bioinformatics, Medical Imaging, Finance, Econometrics and Network Intrusion Detection highlight the usefulness of computational statistics in real-world applications.

Innovations in Multivariate Statistical Modeling

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Publisher : Springer Nature
ISBN 13 : 3031139712
Total Pages : 434 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Innovations in Multivariate Statistical Modeling by : Andriëtte Bekker

Download or read book Innovations in Multivariate Statistical Modeling written by Andriëtte Bekker and published by Springer Nature. This book was released on 2022-12-15 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multivariate statistical analysis has undergone a rich and varied evolution during the latter half of the 20th century. Academics and practitioners have produced much literature with diverse interests and with varying multidisciplinary knowledge on different topics within the multivariate domain. Due to multivariate algebra being of sustained interest and being a continuously developing field, its appeal breaches laterally across multiple disciplines to act as a catalyst for contemporary advances, with its core inferential genesis remaining in that of statistics. It is exactly this varied evolution caused by an influx in data production, diffusion, and understanding in scientific fields that has blurred many lines between disciplines. The cross-pollination between statistics and biology, engineering, medical science, computer science, and even art, has accelerated the vast amount of questions that statistical methodology has to answer and report on. These questions are often multivariate in nature, hoping to elucidate uncertainty on more than one aspect at the same time, and it is here where statistical thinking merges mathematical design with real life interpretation for understanding this uncertainty. Statistical advances benefit from these algebraic inventions and expansions in the multivariate paradigm. This contributed volume aims to usher novel research emanating from a multivariate statistical foundation into the spotlight, with particular significance in multidisciplinary settings. The overarching spirit of this volume is to highlight current trends, stimulate a focus on, and connect multidisciplinary dots from and within multivariate statistical analysis. Guided by these thoughts, a collection of research at the forefront of multivariate statistical thinking is presented here which has been authored by globally recognized subject matter experts.

Statistical Causal Inferences and Their Applications in Public Health Research

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Publisher : Springer
ISBN 13 : 3319412590
Total Pages : 324 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Statistical Causal Inferences and Their Applications in Public Health Research by : Hua He

Download or read book Statistical Causal Inferences and Their Applications in Public Health Research written by Hua He and published by Springer. This book was released on 2016-10-26 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles and presents new developments in statistical causal inference. The accompanying data and computer programs are publicly available so readers may replicate the model development and data analysis presented in each chapter. In this way, methodology is taught so that readers may implement it directly. The book brings together experts engaged in causal inference research to present and discuss recent issues in causal inference methodological development. This is also a timely look at causal inference applied to scenarios that range from clinical trials to mediation and public health research more broadly. In an academic setting, this book will serve as a reference and guide to a course in causal inference at the graduate level (Master's or Doctorate). It is particularly relevant for students pursuing degrees in statistics, biostatistics, and computational biology. Researchers and data analysts in public health and biomedical research will also find this book to be an important reference.

Biostatistics: A Computing Approach

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Publisher : CRC Press
ISBN 13 : 1439897905
Total Pages : 323 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Biostatistics: A Computing Approach by : Stewart Anderson

Download or read book Biostatistics: A Computing Approach written by Stewart Anderson and published by CRC Press. This book was released on 2011-12-20 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of high-speed computing has facilitated the development of many exciting statistical and mathematical methods in the last 25 years, broadening the landscape of available tools in statistical investigations of complex data. Biostatistics: A Computing Approach focuses on visualization and computational approaches associated with both modern and classical techniques. Furthermore, it promotes computing as a tool for performing both analyses and simulations that can facilitate such understanding. As a practical matter, programs in R and SAS are presented throughout the text. In addition to these programs, appendices describing the basic use of SAS and R are provided. Teaching by example, this book emphasizes the importance of simulation and numerical exploration in a modern-day statistical investigation. A few statistical methods that can be implemented with simple calculations are also worked into the text to build insight about how the methods really work. Suitable for students who have an interest in the application of statistical methods but do not necessarily intend to become statisticians, this book has been developed from Introduction to Biostatistics II, which the author taught for more than a decade at the University of Pittsburgh.

Complex Models and Computational Methods in Statistics

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Publisher : Springer
ISBN 13 : 9788847055650
Total Pages : 0 pages
Book Rating : 4.0/5 (556 download)

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Book Synopsis Complex Models and Computational Methods in Statistics by : Matteo Grigoletto

Download or read book Complex Models and Computational Methods in Statistics written by Matteo Grigoletto and published by Springer. This book was released on 2015-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of computational methods in statistics to face complex problems and highly dimensional data, as well as the widespread availability of computer technology, is no news. The range of applications, instead, is unprecedented. As often occurs, new and complex data types require new strategies, demanding for the development of novel statistical methods and suggesting stimulating mathematical problems. This book is addressed to researchers working at the forefront of the statistical analysis of complex systems and using computationally intensive statistical methods.

Flexible Nonparametric Curve Estimation

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Publisher : Springer Nature
ISBN 13 : 3031665015
Total Pages : 309 pages
Book Rating : 4.0/5 (316 download)

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Book Synopsis Flexible Nonparametric Curve Estimation by : Hassan Doosti

Download or read book Flexible Nonparametric Curve Estimation written by Hassan Doosti and published by Springer Nature. This book was released on with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Testing Statistical Hypotheses with Given Reliability

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Publisher : Cambridge Scholars Publishing
ISBN 13 : 1527510646
Total Pages : 333 pages
Book Rating : 4.5/5 (275 download)

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Book Synopsis Testing Statistical Hypotheses with Given Reliability by : Kartlos Joseph Kachiashvili

Download or read book Testing Statistical Hypotheses with Given Reliability written by Kartlos Joseph Kachiashvili and published by Cambridge Scholars Publishing. This book was released on 2023-06-02 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is dedicated to the branch of statistical science which pertains to the theory of hypothesis testing. This involves deciding on the plausibility of two or more hypothetical models based on some data. This work will be both interesting and useful for professional and beginner researchers and practitioners of many fields, who are interested in the theoretical and practical issues of the direction of mathematical statistics, namely, in statistical hypothesis testing. It will also be very useful for specialists of different fields for solving suitable problems at the appropriate level, as the book discusses in detail many important practical problems and provides detailed algorithms for their solutions.

Statistical Methods for Dynamic Treatment Regimes

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Publisher : Springer Science & Business Media
ISBN 13 : 1461474280
Total Pages : 220 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Statistical Methods for Dynamic Treatment Regimes by : Bibhas Chakraborty

Download or read book Statistical Methods for Dynamic Treatment Regimes written by Bibhas Chakraborty and published by Springer Science & Business Media. This book was released on 2013-07-23 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Methods for Dynamic Treatment Regimes shares state of the art of statistical methods developed to address questions of estimation and inference for dynamic treatment regimes, a branch of personalized medicine. This volume demonstrates these methods with their conceptual underpinnings and illustration through analysis of real and simulated data. These methods are immediately applicable to the practice of personalized medicine, which is a medical paradigm that emphasizes the systematic use of individual patient information to optimize patient health care. This is the first single source to provide an overview of methodology and results gathered from journals, proceedings, and technical reports with the goal of orienting researchers to the field. The first chapter establishes context for the statistical reader in the landscape of personalized medicine. Readers need only have familiarity with elementary calculus, linear algebra, and basic large-sample theory to use this text. Throughout the text, authors direct readers to available code or packages in different statistical languages to facilitate implementation. In cases where code does not already exist, the authors provide analytic approaches in sufficient detail that any researcher with knowledge of statistical programming could implement the methods from scratch. This will be an important volume for a wide range of researchers, including statisticians, epidemiologists, medical researchers, and machine learning researchers interested in medical applications. Advanced graduate students in statistics and biostatistics will also find material in Statistical Methods for Dynamic Treatment Regimes to be a critical part of their studies.

Statistical Methods for the Analysis of Biomedical Data

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Publisher : John Wiley & Sons
ISBN 13 : 111803130X
Total Pages : 714 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Statistical Methods for the Analysis of Biomedical Data by : Robert F. Woolson

Download or read book Statistical Methods for the Analysis of Biomedical Data written by Robert F. Woolson and published by John Wiley & Sons. This book was released on 2011-01-25 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieser Band behandelt eine Reihe statistischer Themen, die bei der Analyse biologischer und medizinischer Daten allgemein Anwendung finden. Diese 2. Auflage wurde komplett überarbeitet, aktualisiert und erweitert. Einige Kapitel sind neu hinzugekommen, u.a. zur multiplen linearen Regression in der biomedizinischen Forschung. Der Stoff ist so gegliedert, dass der Leser den Text unabhängig von der jeweiligen statistischen Methode leicht nach Problemstellungen durchsuchen kann. Mit zahlreichen durchgearbeiteten Beispielen, die detaillierte Lösungsangaben zu Problemen aus der Praxis liefern.

Model-Assisted Bayesian Designs for Dose Finding and Optimization

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Author :
Publisher : CRC Press
ISBN 13 : 0429628471
Total Pages : 234 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Model-Assisted Bayesian Designs for Dose Finding and Optimization by : Ying Yuan

Download or read book Model-Assisted Bayesian Designs for Dose Finding and Optimization written by Ying Yuan and published by CRC Press. This book was released on 2022-11-11 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian adaptive designs provide a critical approach to improve the efficiency and success of drug development that has been embraced by the US Food and Drug Administration (FDA). This is particularly important for early phase trials as they form the basis for the development and success of subsequent phase II and III trials. The objective of this book is to describe the state-of-the-art model-assisted designs to facilitate and accelerate the use of novel adaptive designs for early phase clinical trials. Model-assisted designs possess avant-garde features where superiority meets simplicity. Model-assisted designs enjoy exceptional performance comparable to more complicated model-based adaptive designs, yet their decision rules often can be pre-tabulated and included in the protocol—making implementation as simple as conventional algorithm-based designs. An example is the Bayesian optimal interval (BOIN) design, the first dose-finding design to receive the fit-for-purpose designation from the FDA. This designation underscores the regulatory agency's support of the use of the novel adaptive design to improve drug development. Features Represents the first book to provide comprehensive coverage of model-assisted designs for various types of dose-finding and optimization clinical trials Describes the up-to-date theory and practice for model-assisted designs Presents many practical challenges, issues, and solutions arising from early-phase clinical trials Illustrates with many real trial applications Offers numerous tips and guidance on designing dose finding and optimization trials Provides step-by-step illustrations of using software to design trials Develops a companion website (www.trialdesign.org) to provide freely available, easy-to-use software to assist learning and implementing model-assisted designs Written by internationally recognized research leaders who pioneered model-assisted designs from the University of Texas MD Anderson Cancer Center, this book shows how model-assisted designs can greatly improve the efficiency and simplify the design, conduct, and optimization of early-phase dose-finding trials. It should therefore be a very useful practical reference for biostatisticians, clinicians working in clinical trials, and drug regulatory professionals, as well as graduate students of biostatistics. Novel model-assisted designs showcase the new KISS principle: Keep it simple and smart!

Biostatistics with R

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Publisher : Springer Science & Business Media
ISBN 13 : 1461413028
Total Pages : 355 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Biostatistics with R by : Babak Shahbaba

Download or read book Biostatistics with R written by Babak Shahbaba and published by Springer Science & Business Media. This book was released on 2011-12-15 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biostatistics with R is designed around the dynamic interplay among statistical methods, their applications in biology, and their implementation. The book explains basic statistical concepts with a simple yet rigorous language. The development of ideas is in the context of real applied problems, for which step-by-step instructions for using R and R-Commander are provided. Topics include data exploration, estimation, hypothesis testing, linear regression analysis, and clustering with two appendices on installing and using R and R-Commander. A novel feature of this book is an introduction to Bayesian analysis. This author discusses basic statistical analysis through a series of biological examples using R and R-Commander as computational tools. The book is ideal for instructors of basic statistics for biologists and other health scientists. The step-by-step application of statistical methods discussed in this book allows readers, who are interested in statistics and its application in biology, to use the book as a self-learning text.