Comprehensive Review In Clinical Toxicology

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A Comprehensive Guide to Toxicology in Preclinical Drug Development

Author : Ali S. Faqi
Publisher : Academic Press
ISBN 13 : 0123878160
Total Pages : 903 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis A Comprehensive Guide to Toxicology in Preclinical Drug Development by : Ali S. Faqi

Download or read book A Comprehensive Guide to Toxicology in Preclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2012-10-18 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. - Chapters written by world-renowned contributors who are experts in their fields - Includes the latest research in preclinical drug testing and international guidelines - Covers preclinical toxicology in small molecules and biologics in one single source

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

Author : Ali S. Faqi
Publisher : Academic Press
ISBN 13 : 0128036214
Total Pages : 988 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis A Comprehensive Guide to Toxicology in Nonclinical Drug Development by : Ali S. Faqi

Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2016-11-03 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. - Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more - Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules - Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology

Molecular, Clinical and Environmental Toxicology

Author : Andreas Luch
Publisher : Springer Science & Business Media
ISBN 13 : 3764383380
Total Pages : 620 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Molecular, Clinical and Environmental Toxicology by : Andreas Luch

Download or read book Molecular, Clinical and Environmental Toxicology written by Andreas Luch and published by Springer Science & Business Media. This book was released on 2010-03-01 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Comprehensive Review of Psychiatry

Author : Rajesh R. Tampi
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781771764
Total Pages : 676 pages
Book Rating : 4.7/5 (717 download)

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Book Synopsis Comprehensive Review of Psychiatry by : Rajesh R. Tampi

Download or read book Comprehensive Review of Psychiatry written by Rajesh R. Tampi and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: Derived from a popular review course for residents and fellows at Yale University's Department of Psychiatry, this comprehensive question-and-answer review book will prepare resident and practicing psychiatrists for all types of standardized examinations, including the PRITE, the American Board of Psychiatry and Neurology written exam, and recertification exams. The book contains 2,000 multiple-choice questions divided into ten 200-question tests, and each test covers all psychiatry and neurology topics in the ABPN curriculum. An answer section with complete answers, explanations, and references for further review follows each test. All of the questions will be available on a companion Website, so that readers can take the tests online. (www.comprehensivereviewofpsychiatry.com)

Handbook of Clinical Toxicology of Animal Venoms and Poisons

Author : Julian White
Publisher : CRC Press
ISBN 13 : 9780849344893
Total Pages : 50 pages
Book Rating : 4.3/5 (448 download)

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Book Synopsis Handbook of Clinical Toxicology of Animal Venoms and Poisons by : Julian White

Download or read book Handbook of Clinical Toxicology of Animal Venoms and Poisons written by Julian White and published by CRC Press. This book was released on 1995-08-22 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Clinical Toxicology of Animal Venoms is the first concise, one-volume book devoted to this important subject. The editors are internationally recognized authorities in the biology and clinical aspects of venomous and poisonous animals, and the chapter authors are world leaders in their respective fields of toxicology. All aspects of the topic are covered including information on the biology and taxonomy of poisonous animals, their venom or poison, diagnosis, and general treatment principles and specific treatment. The most up-to-date list of available antivenoms is provided. Coverage of venomous and poisonous animals is comprehensive, with thorough discussions on shellfish poisoning, ciguatera, fugu, coelenterates, stingrays, venous fish, blue-ringed octopus, sea-snakes, scorpions, spiders, insects, and gila lizards. Individual chapters focus on snakes and snakebite in Europe, Africa, Asia, Australia, North America, Central America, and South America. Nearly all clinical chapters have been written by clinicians with extensive experience treating the particular type of animal envenoming or poisoning under consideration. No other book brings together such a wealth of information in this field, and no other book provides it in a format useful to clinicians charged with the responsibility of treating envenomed or poisoned patients. The Handbook of Clinical Toxicology of Animal Venoms is an essential addition to all medical libraries, emergency departments, toxicology departments, poison information centers, and invaluable to all professionals working in these fields.

Toxicology

Author : John Joseph Fenton
Publisher : CRC Press
ISBN 13 : 1420042068
Total Pages : 585 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Toxicology by : John Joseph Fenton

Download or read book Toxicology written by John Joseph Fenton and published by CRC Press. This book was released on 2001-10-10 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: REAL-LIFE CASES, TUTORIAL QUESTIONS, NARRATIVE HISTORY Intriguing anecdotal pedagogy, like the alleged arsenical poisonings of Napoleon and President Taylor and the probable mercury overdose of Isaac Newton, is one of the things that set Toxicology: A Case-Oriented Approach apart from other toxicology texts. Based on an undergraduate-graduat

Small Animal Toxicology

Author : Patricia A. Talcott
Publisher : Elsevier Health Sciences
ISBN 13 : 0323241980
Total Pages : 955 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Small Animal Toxicology by : Patricia A. Talcott

Download or read book Small Animal Toxicology written by Patricia A. Talcott and published by Elsevier Health Sciences. This book was released on 2012-12-03 with total page 955 pages. Available in PDF, EPUB and Kindle. Book excerpt: - 20 new chapters have been added - New topics include a list of toxicants affecting body systems, management of toxins in pregnancy, diagnostic toxicology, bacterial toxins, and cosmetic/toilet articles - Snake-bite injuries are treated in two separate, expanded chapters: Pit Vipers and Coral Snakes - Section on pharmaceuticals includes bromides, anticonvulsants, tricycle antidepressants, monoamine oxidize inhibitors, B-adrenergic toxicities, and vitamins A and D - Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods•Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods.

Clinical Environmental Health and Toxic Exposures

Author : John Burke Sullivan
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780683080278
Total Pages : 1348 pages
Book Rating : 4.0/5 (82 download)

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Book Synopsis Clinical Environmental Health and Toxic Exposures by : John Burke Sullivan

Download or read book Clinical Environmental Health and Toxic Exposures written by John Burke Sullivan and published by Lippincott Williams & Wilkins. This book was released on 2001 with total page 1348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its revised and updated Second Edition, this volume is the most comprehensive and authoritative text in the rapidly evolving field of environmental toxicology. The book provides the objective information that health professionals need to prevent environmental health problems, plan for emergencies, and evaluate toxic exposures in patients.Coverage includes safety, regulatory, and legal issues; clinical toxicology of specific organ systems; emergency medical response to hazardous materials releases; and hazards of specific industries and locations. Nearly half of the book examines all known toxins and environmental health hazards. A Brandon-Hill recommended title.

Information Resources in Toxicology

Author : P.J. Bert Hakkinen
Publisher : Elsevier
ISBN 13 : 008053466X
Total Pages : 953 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Information Resources in Toxicology by : P.J. Bert Hakkinen

Download or read book Information Resources in Toxicology written by P.J. Bert Hakkinen and published by Elsevier. This book was released on 2000-01-10 with total page 953 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. - Serves as an all-in-one resource for toxicology information - New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports - Updated to include the latest internet and electronic sources, e-mail addresses, etc. - Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects

Principles and Practice of Skin Toxicology

Author : Robert Chilcott
Publisher : John Wiley & Sons
ISBN 13 : 0470773081
Total Pages : 392 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Principles and Practice of Skin Toxicology by : Robert Chilcott

Download or read book Principles and Practice of Skin Toxicology written by Robert Chilcott and published by John Wiley & Sons. This book was released on 2008-07-31 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.

Comprehensive Reviews in Toxicology

Author : Peter D Bryson
Publisher : CRC Press
ISBN 13 : 9781560326120
Total Pages : 890 pages
Book Rating : 4.3/5 (261 download)

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Book Synopsis Comprehensive Reviews in Toxicology by : Peter D Bryson

Download or read book Comprehensive Reviews in Toxicology written by Peter D Bryson and published by CRC Press. This book was released on 1996-09-03 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised and updated, this edition covers general principles of overdose management; the automonic nervous system, neurotransmitters and drugs; drugs used in psychiatry; cardiac drugs; agents that burn; gases and abnormal haemoglobin formation; the

Clinical Management of Poisoning and Drug Overdose

Author : Lester M. Haddad
Publisher :
ISBN 13 : 9780721664095
Total Pages : 0 pages
Book Rating : 4.6/5 (64 download)

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Book Synopsis Clinical Management of Poisoning and Drug Overdose by : Lester M. Haddad

Download or read book Clinical Management of Poisoning and Drug Overdose written by Lester M. Haddad and published by . This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here's a comprehensive and clinically-specific reference on toxicology. The 3rd Edition includes chapters on overdose during rapid-sequence intubation and conscious sedation, management of complications of thrombolytic agents, and the application of hyperbaric medicine in toxicology. Provides the perfect balance of basic pharmacokinetics and clinical management. Contributions are by experts in the field. Contains completely rewritten and reorganized coverage to encompass the background, pharmacology, pathophysiology, diagnosis, and management of each toxin for clinical treatment throughout a patient's hospital stay. Features a new editor--Michael Shannon, MD--whose experience in pediatric emergency medicine expands the text's coverage of pediatrics...and almost 60 new contributing experts who have made original contributions to their field, with a majority certified by the first approved subspecialty board in toxicology. Presents 10 new chapters that cover: pediatric resuscitation, antibiotic hypersensitivity and anaphylaxis, MAO inhibitors and the serotonin syndrome, herbal and alternative medicine, and thrombolytic therapy, and more. OUTSTANDING FEATURES: Uses a clinical approachfor maximum clinical relevance, addressing how toxins affect humans, not animals. Incorporates the experience of many expert authors from numerous specialties for a Comprehensive review of toxicology and an authoritative overview of each specialty. Contains colour plates of toxic natural life, including various snakes, mushrooms, plants, and marine life--a feature unique to this book.

Clinical Neurotoxicology E-Book

Author : Michael R. Dobbs
Publisher : Elsevier Health Sciences
ISBN 13 : 032307099X
Total Pages : 729 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Clinical Neurotoxicology E-Book by : Michael R. Dobbs

Download or read book Clinical Neurotoxicology E-Book written by Michael R. Dobbs and published by Elsevier Health Sciences. This book was released on 2009-07-22 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You’ll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors—such as heavy metals and pesticides—and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. Provides a complete listing of neurotoxic agents—from manufactured to environmental—so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson’s Disease, motor neuron disease, as well as other issues that are still in question.

Toxicology Cases for the Clinical and Forensic Laboratory

Author : Hema Ketha
Publisher : Academic Press
ISBN 13 : 0128163739
Total Pages : 542 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Toxicology Cases for the Clinical and Forensic Laboratory by : Hema Ketha

Download or read book Toxicology Cases for the Clinical and Forensic Laboratory written by Hema Ketha and published by Academic Press. This book was released on 2020-06-20 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both. - Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format - Presents unique and challenging cases in clinical laboratories contributed by experts in the field - Consolidated format that make concepts in toxicology easy to learn and teach - Key learning points highlighted with multiple choice questions

Medical Toxicology

Author : Richard C. Dart
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781728454
Total Pages : 1990 pages
Book Rating : 4.7/5 (284 download)

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Book Synopsis Medical Toxicology by : Richard C. Dart

Download or read book Medical Toxicology written by Richard C. Dart and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 1990 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised and updated Third Edition of the classic Medical Toxicology is the definitive reference on the management of poisoned patients. More than 300 well-organized chapters written by eminent authorities guide clinicians through the diagnosis and treatment of every poisoning or drug overdose. Chapter outlines, headings, and a detailed index enable readers to quickly locate exactly the information they need. This edition includes new chapters on biological and chemical weapons and on diagnosis of patients with apparent symptoms of poisoning when the cause is unknown. The book includes comparative commentary on toxicology practice in the United States, Europe, Australia, and Asia. Compatibility: BlackBerry® OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile™ Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC

Blackwell's Five-Minute Veterinary Consult Clinical Companion

Author : Lynn Hovda
Publisher : John Wiley & Sons
ISBN 13 : 1119036526
Total Pages : 984 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Blackwell's Five-Minute Veterinary Consult Clinical Companion by : Lynn Hovda

Download or read book Blackwell's Five-Minute Veterinary Consult Clinical Companion written by Lynn Hovda and published by John Wiley & Sons. This book was released on 2016-02-29 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blackwell's Five-Minute Veterinary Consult Clinical Companion: Small Animal Toxicology, Second Edition puts all the information needed to rapidly and accurately manage poisonings in small animal patients at the clinician's fingertips. Provides concise, bulleted information focused on the most important facts needed when treating a poisoned cat or dog Carefully organized for ease of use in an emergency, with important toxicants arranged alphabetically within categories Details clinically relevant information on the most common toxicants encountered by small animals Presents a wealth of color photographs to aid in plant identification Includes 14 new topics to this edition covering cyclosporine A, sleep aids, tacrolimus, bath salts, synthetic marijuana, poisonous lizards, imidacloprid, spring bulbs, and sodium monofluoroacetate

Information Resources in Toxicology, Volume 1: Background, Resources, and Tools

Author :
Publisher : Academic Press
ISBN 13 : 0128137258
Total Pages : 1055 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Information Resources in Toxicology, Volume 1: Background, Resources, and Tools by :

Download or read book Information Resources in Toxicology, Volume 1: Background, Resources, and Tools written by and published by Academic Press. This book was released on 2020-05-16 with total page 1055 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field