Compound 26

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Compound 26

Author : Krista Street
Publisher : Krista Street
ISBN 13 : 1946884081
Total Pages : 330 pages
Book Rating : 4.9/5 (468 download)

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Book Synopsis Compound 26 by : Krista Street

Download or read book Compound 26 written by Krista Street and published by Krista Street. This book was released on 2018-02-08 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: A deadly virus. A brilliant, young researcher. And an infected survivor who threatens to steal her heart. In a society ruled by sanctions and curfews, Dr. Meghan Forester emerges as the youngest and most promising scientist to join the fight against Makanza—the deadly virus that's ravaged the world. Inside Compound 26, a giant government-controlled research facility, Meghan's new job involves studying the Kazzies, the rare survivors who carry the virus and now exhibit supernatural powers. But as her work unfolds, Meghan's horrified at the brutal and unethical practices the Kazzies are subjected to. And most surprisingly, she falls in love with one. Faced with growing conflict over helping the Kazzies versus following the Compound's strict policies, Meghan must choose: obey the government's unethical practices or risk everything to save the only man she's ever loved. The Makanza Series is a complete series in which fantastical powers collide with modern science. Dive into this imaginative and romantic series today. Download now! READ THE COMPLETE SERIES in ebook, paperback or listen on audio! The Makanza Series - a dystopian romance series Book 0 (prequel): The Second Wave Book 1: Compound 26 Book 2: Reservation 1 Book 3: Section 12 Book 4: Division 5 Keywords: dystopian romance, YA science fiction, YA dystopian, science fiction romance, complete YA series, YA post-apocalyptic romance, complete science fantasy series, books for teens, YA books, post-apocalyptic books, post-apocalyptic romance, post-apoc romance. Other authors you may enjoy: Veronica Roth, Suzanne Collins, Dean Koontz, Sophie Davis, Stephenie Meyers, & Tahereh Mafi.

Integration of Pharmaceutical Discovery and Development

Author : Ronald T. Borchardt
Publisher : Springer Science & Business Media
ISBN 13 : 0306473844
Total Pages : 627 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Integration of Pharmaceutical Discovery and Development by : Ronald T. Borchardt

Download or read book Integration of Pharmaceutical Discovery and Development written by Ronald T. Borchardt and published by Springer Science & Business Media. This book was released on 2006-01-19 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift occurred in which drug design and development activities became more highly integrated. This new str- egy required medicinal chemists to design drug candidates with structural f- tures that optimized pharmacological (e. g. , high affinity and specificity for the target receptor), pharmaceutical (e. g. , solubility and chemical stability), bioph- maceutical (e. g. , cell membrane permeability), and metabolic/pharmacokinetic (e. g. , metabolic stability, clearance, and protein binding) properties. Successful implementation of this strategy requires a multidisciplinary team effort, incl- ing scientists from drug design (e. g. , medicinal chemists, cell biologists, en- mologists, pharmacologists) and drug development (e. g. , analytical chemists, pharmaceutical scientists, physiologists, and molecular biologists representing the disciplines of pharmaceutics, biopharmaceutics, and pharmacokinetics/drug metabolism). With this new, highly integrated approach to drug design now widely utilized by the pharmaceutical industry, the editors of this book have provided the sci- tific community with case histories to illustrate the nature of the interdisciplinary interactions necessary to successfully implement this new approach to drug d- covery. In the first chapter, Ralph Hirschmann provides a historical perspective of why this paradigm shift in drug discovery has occurred.

Strategies and Tactics in Organic Synthesis

Author : Michael Harmata
Publisher : Academic Press
ISBN 13 : 0128148063
Total Pages : 352 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Strategies and Tactics in Organic Synthesis by : Michael Harmata

Download or read book Strategies and Tactics in Organic Synthesis written by Michael Harmata and published by Academic Press. This book was released on 2019-11-19 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategies and Tactics in Organic Synthesis, Volume 14, provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure, and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs, and building molecules with atom and step economies that provide functional solutions to create a better world. - Presents state-of-the-art developments in organic synthesis - Provides insights and offers new perspectives on problem-solving - Written by leading experts in the field - Uses firsthand narrative accounts to vividly illustrate the challenges and joys involved in advancing the science of organic synthesis

Spirooxindole

Author : Gautam Patel
Publisher : Elsevier
ISBN 13 : 0443223254
Total Pages : 660 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Spirooxindole by : Gautam Patel

Download or read book Spirooxindole written by Gautam Patel and published by Elsevier. This book was released on 2024-06-12 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern advances in organic synthesis require compouds having attractive properties with high percentage of yield. Spirooxindole examines the current state of the art, recent progress and new challenges associated with the development of spirooxindole derivatives for various medicinal applications. Owing to their exceptional properties, these compounds can be used in vaious fields, including chemical and pharma industries, and in clinical research. This book has chapters written by experts in several different areas. It serves as a useful reference book for scientists, industrial practitioners, graduate students, and other professionals in the field of hetrocyclic chemistry, medicinal chemistry, organic synthesis clinical research and chemical sciences.The growing interest among the academics and industrial researchers in the field of organic chemistry and medicinal chemistry is the driving force for the presentation of this edited book. - Consolidates information on each aspect of this novel compound and its applications in various fields, covering the entire spectrum of up-to-date literature citations, current market, and patents - Provides a comprehensive, in-depth description of spirooxindole derivatives as well as multipurpose scaffolds - Highlights green synthesis and nanocatalysis - Describes in-depth various medicinal applications - Covers both synthesis and applications

Progress in Medicinal Chemistry

Author :
Publisher : Elsevier
ISBN 13 : 0444639438
Total Pages : 196 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Progress in Medicinal Chemistry by :

Download or read book Progress in Medicinal Chemistry written by and published by Elsevier. This book was released on 2017-03-15 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Medicinal Chemistry, Volume 56 provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a potential new era for Chagas Disease drug discovery, and imaging in drug development. Specific chapters cover timely topics, such as the development of LRRK2 inhibitors for the treatment of Parkinson's, and recent discoveries and developments in TRPA1 modulators. Users will find a comprehensive resource on the topic of medicinal chemistry that also discusses avenues for the acceleration of drug discovery programs. - Extended, timely reviews of topics in medicinal chemistry - Contains targets and technologies relevant to the discovery of tomorrow's drugs - Presents analyses of successful drug discovery programs

Nuclear Science Abstracts

Author :
Publisher :
ISBN 13 :
Total Pages : 1472 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Nuclear Science Abstracts by :

Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1972 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Allosterism in Drug Discovery

Author : Dario Doller
Publisher : Royal Society of Chemistry
ISBN 13 : 1782624597
Total Pages : 458 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Allosterism in Drug Discovery by : Dario Doller

Download or read book Allosterism in Drug Discovery written by Dario Doller and published by Royal Society of Chemistry. This book was released on 2016-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the concept of allosterism has been known for over half a century, its application in drug discovery has exploded in recent years. The emergence of novel technologies that enable molecular-level ligand-receptor interactions to be studied in studied in unprecedented detail has driven this trend. This book, written by the leaders in this young research area, describes the latest developments in allosterism for drug discovery. Bringing together research in a diverse range of scientific disciplines, Allosterism in Drug Discovery is a key reference for academics and industrialists interested in understanding allosteric interactions. The book provides an in-depth review of research using small molecules as chemical probes and drug candidates that interact allosterically with proteins of relevance to life sciences and human disease. Knowledge of these interactions can then be applied in the discovery of the novel therapeutics of the future. This book will be useful for people working in all disciplines associated with drug discovery in academia or industry, as well as postgraduate students who may be working in the design of allosteric modulators.

Contemporary Accounts in Drug Discovery and Development

Author : Xianhai Huang
Publisher : John Wiley & Sons
ISBN 13 : 1119627818
Total Pages : 484 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Contemporary Accounts in Drug Discovery and Development by : Xianhai Huang

Download or read book Contemporary Accounts in Drug Discovery and Development written by Xianhai Huang and published by John Wiley & Sons. This book was released on 2022-03-11 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: CONTEMPORARY ACCOUNTS IN DRUG DISCOVERY AND DEVELOPMENT A useful guide for medicinal chemists and pharmaceutical scientists Drug discovery is a lengthy and complex process that typically involves identifying an unmet medical need, determining a biological target, chemical library screening to identify a lead, chemical optimization, preclinical studies and clinical trials. This process often takes many years to complete, and relies on practitioners’ knowledge of chemistry and biology, but also—and perhaps more importantly—on experience. Improving the success rate in discovery and development through a thorough knowledge of drug discovery principles and advances in technology is critical for advancement in the field. Contemporary Accounts in Drug Discovery and Development provides drug discovery scientists with the knowledge they need to quickly gain mastery of the drug discovery process. A thorough accounting is given for each drug covered within the book, as the authors provide pharmacology, drug metabolism, biology, drug development, and clinical studies for every case, with modern drug discovery principles and technologies incorporated throughout. Contemporary Accounts in Drug Discovery and Development readers will also find Case histories used as an engaging way of learning about the drug discovery/development process Detailed biological rational and background information, drug design principles, SAR development, ADMET considerations, and clinical studies The full history of individual marketed small molecule drugs Coverage of drug candidates that have passed Phase I clinical trials with different modalities, such as antibody drug conjugates (ADC), proteolysis-targeting chimera (PROTAC), and peptide drugs The application of new technologies in drug discovery such as DNA-encoded libraries (DEL), positron emission tomography (PET), and physics-based computational modeling employing free energy perturbation (FEP) Contemporary Accounts in Drug Discovery and Development is a helpful tool for medicinal chemists, organic chemists, pharmacologists, and other scientists in drug research and process development. It may be considered essential reading for graduate courses in drug discovery, medicinal chemistry, drug synthesis, pharmaceutical science, and pharmacology. It is also a useful resource for pharmaceutical industry labs, as well as for libraries.

Preston's Complete Time Table

Author : Lyman Preston
Publisher :
ISBN 13 :
Total Pages : 326 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis Preston's Complete Time Table by : Lyman Preston

Download or read book Preston's Complete Time Table written by Lyman Preston and published by . This book was released on 1849 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Kinase Inhibitors

Author : Md. Imtaiyaz Hassan
Publisher : Academic Press
ISBN 13 : 0323913490
Total Pages : 832 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Protein Kinase Inhibitors by : Md. Imtaiyaz Hassan

Download or read book Protein Kinase Inhibitors written by Md. Imtaiyaz Hassan and published by Academic Press. This book was released on 2022-05-19 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Kinase Inhibitors: From Discovery to Therapeutics offers a foundational, pragmatic overview of protein kinases inhibitors and their potential role in disease modulation and treatment. Here, international experts in the field offer an integrated discussion of kinase inhibitor biology, biomarker discovery, and methods for drug design and development. After a brief overview of kinases and kinase inhibitors, subsequent chapters discuss individual kinases that are representative of the wider kinases and kinase families, including their roles in disease pathogenesis, underlying mechanisms, potential inhibitors and their modes of action for therapeutic modulation. Several potential drugs under different stages of clinical trials are discussed, including their relevance to cancer, diabetes, obesity, cardiovascular, neurological, and auto-immune and inflammatory disease, among other disorders. The book also addresses the challenges and opportunities for future kinase inhibitor development. - Provides a thorough overview of kinase inhibitor biology and its role in disease progression and modulation - Examines protein kinase inhibitor drugs in various stages of clinical trials and development - Offers methods and protocols for protein kinase inhibitor research studies and drug design and development - Includes chapter contributions from international leaders in the field

Crown Ethers and Analogous Compounds

Author : M. Hiraoka
Publisher : Elsevier
ISBN 13 : 1483290875
Total Pages : 500 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Crown Ethers and Analogous Compounds by : M. Hiraoka

Download or read book Crown Ethers and Analogous Compounds written by M. Hiraoka and published by Elsevier. This book was released on 2016-05-04 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of crown ethers by Pedersen in 1967, several thousands of crown ethers and analogous compounds have been synthesized. Their specific characteristics have been investigated and a variety of applications developed. These developments have led to new fields of chemistry called host-guest chemistry and supramolecular chemistry. This book presents the state-of-the-art of the chemistry of crown ethers and analogous compounds. The first chapter provides an orientation in the new fields of chemistry. Chapter 2 reviews advances in synthetic procedures for crown ethers and analogous compounds including azacrown ethers, thiacrown ethers, functionalized crown ethers, cryptands and others. The focus of chapter 3 is on the concept and synthetic strategies for the molecular design of new crown compounds. Chapters 4-7 are concerned with noteworthy topics in the applications of crown compounds. Chapter 4 deals with the application to ion-selective electrodes and liquid chromatography, both of which are the most important targets in the analytical application of crown compounds. One major application of crown ethers is the design and syntheses of artificial molecules which can catalyze a useful synthetic reaction in an enzyme-mimetic reaction manner, through novel non-covalent complexes. The strategies for enzymatic modelling with crown ethers are covered in chapter 5, while chapter 6 presents the principle of amine-selective colour complexation and its application. In chapter 7 switched-on crown ethers that can respond to environmental stimuli are reviewed. The final chapter is devoted to a wide-ranging discussion of developments in macrocyclic polyamine chemistry. Unlike crown ethers, macrocyclic polyamines, bearing nitrogen donor atoms which belong to a soft base, form complexes with ions of transition metals and heavy metals which are classified as soft acids. Therefore, macrocyclic polyamines are expected to have very versatile applications. Scientists in chemistry, biochemistry, physical organic chemistry, pharmaceutical chemistry and industrial chemistry will find this book a helpful summary and a stimulating contribution to research in this specialized field of crown compounds.

Asymmetric Synthesis of Drugs and Natural Products

Author : Ahindra Nag
Publisher : CRC Press
ISBN 13 : 1315302306
Total Pages : 498 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Asymmetric Synthesis of Drugs and Natural Products by : Ahindra Nag

Download or read book Asymmetric Synthesis of Drugs and Natural Products written by Ahindra Nag and published by CRC Press. This book was released on 2018-01-12 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on different techniques of asymmetric synthesis of important compounds, such as drugs and natural products. It gives insightful information on recent asymmetric synthesis by Inorganic, Organic and Enzymatic combinations. It also emphasizes chiral compounds and design of new catalyst for synthesis of compounds.

Current Pharmaceutical Design

Author :
Publisher :
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4./5 ( download)

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Book Synopsis Current Pharmaceutical Design by :

Download or read book Current Pharmaceutical Design written by and published by . This book was released on 1995-10 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

N-Heterocyclic Carbenes

Author : Steven P. Nolan
Publisher : John Wiley & Sons
ISBN 13 : 3527671242
Total Pages : 690 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis N-Heterocyclic Carbenes by : Steven P. Nolan

Download or read book N-Heterocyclic Carbenes written by Steven P. Nolan and published by John Wiley & Sons. This book was released on 2014-07-07 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference and handbook covers in depth all major aspects of the use of N-heterocyclic carbene-complexes in organic synthesis: from the theoretical background to characterization, and from cross-coupling reactions to olefin metathesis. Edited by a leader and experienced scientist in the field of homogeneous catalysis and use of NHCs, this is an essential tool for every academic and industrial synthetic chemist.

Elements and Compounds

Author : Lynnette Brent
Publisher : Crabtree Publishing Company
ISBN 13 : 9780778742425
Total Pages : 36 pages
Book Rating : 4.7/5 (424 download)

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Book Synopsis Elements and Compounds by : Lynnette Brent

Download or read book Elements and Compounds written by Lynnette Brent and published by Crabtree Publishing Company. This book was released on 2009 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: This entertaining and insightful book will show young readers about the chemical compounds that make up the world around them. Colorful illustrations encourage interest in this vital basic science, giving readers knowledge of the periodic table and the importance of chemical compounds in their lives.

The Chemistry of Phenols

Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470869453
Total Pages : 1694 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis The Chemistry of Phenols by :

Download or read book The Chemistry of Phenols written by and published by John Wiley & Sons. This book was released on 2004-08-13 with total page 1694 pages. Available in PDF, EPUB and Kindle. Book excerpt: As phenols represent an important functional group category, The Chemistry of Phenols is an essential addition to any chemistry library. Written by experts, all aspects concerning these compounds are covered making this an essential reference book, bringing together invaluable information into one source for organic, organometallic chemists as well as chemists from a variety of other organic sub-disciplines. Single Source information – essential for organic, organometallic and chemists from organic sub-disciplines Covers phenols as anti-oxidants, synthetic intermediates, polymers and hydrogen bonds Discusses electrophilic and photochemical reactions The Patai Series publishes comprehensive reviews on all aspects of specific functional groups. Each volume contains outstanding surveys on theoretical and computational aspects, NMR, MS, other spectroscopic methods and analytical chemistry, structural aspects, thermochemistry, photochemistry, synthetic approaches and strategies, synthetic uses and applications in chemical and pharmaceutical industries, biological, biochemical and environmental aspects. To date, over 100 volumes have been published in the series. Also Available Online The Chemistry of Phenols as well as the other titles within the Patai Series is also available in electronic format on Wiley InterScience. All new titles will be published online and a growing list of older titles will be added every year.

Cancer Chemotherapy Reports

Author :
Publisher :
ISBN 13 :
Total Pages : 1044 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer Chemotherapy Reports by :

Download or read book Cancer Chemotherapy Reports written by and published by . This book was released on 1974 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: