Composition, Morphology and Crystallinity Biomaterials Based on Calcium Phosphate for Implant Bone Regeneration

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Composition, Morphology and Crystallinity Biomaterials Based on Calcium Phosphate for Implant Bone Regeneration by : Fernando M Abreu

Download or read book Composition, Morphology and Crystallinity Biomaterials Based on Calcium Phosphate for Implant Bone Regeneration written by Fernando M Abreu and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The alveolar bone and surrounding soft tissues must present volume and ideal qualities in order to receive implants. When these characteristics are lacking, biomaterials based on Ca and PO4 composition are regularly used to obtain adequate bone volume and height. The inorganic phase of bones and teeth is characterized by a dominant concentration of calcium phosphate. This has led researchers to develop biomaterials with similar chemical composition and characteristics. The present study analyzed the chemical composition, morphological aspect and crystallinity of four biomaterials, Bio-Oss, Cerasorb, BoneCeramic and Osteogen. The analyses applied were instrumental neutron activation (NAA), energy dispersive X-ray (DX), elemental analysis (EA), X-ray diffraction (XRD), thermogravimetric (TGA), scanning electron microscopy (SEM) and energy dispersive spectroscopy (SEM/EDS). The chemical analyses were effective and detected differences in the elemental composition between the studied biomaterials. The most highly concentrated elements in the biomaterials based on calcium phosphate were Ca and P. Other elements (Al, K, V, Mn, Br, La, Sm, Eu, W, Na, Mg, Si, S, Cl, Fe, Zn, Sr) that are not usually found in the inorganic bone structure were also detected. Thermogravimetric curves agree with the data of the elemental analysis of C, H and N, regarding the content of organic groups, however in Cerasorb, no data could be identified due to the lack of organic elements. Osteogen and Boneceramic, perhaps are synthetic elaboration, presented a low carbon content (0.23% and 0.12%). Morphological data assessed using SEM revealed that these four biomaterials are quite different in shape, surface topography and crystalline size. The biomaterial features may determine their biological, biochemical and biomechanical performance during bone formation and, consequently, their successful clinical use.

Advanced Synthesis and Medical Applications of Calcium Phosphates

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Publisher : CRC Press
ISBN 13 : 1040021263
Total Pages : 180 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Advanced Synthesis and Medical Applications of Calcium Phosphates by : S.S. Nanda

Download or read book Advanced Synthesis and Medical Applications of Calcium Phosphates written by S.S. Nanda and published by CRC Press. This book was released on 2024-05-15 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium phosphate materials are used in many medical and dental applications. Advanced Synthesis and Medical Applications of Calcium Phosphates covers the structure, chemistry, synthesis, and properties of both natural and synthetic calcium-based biomaterials and details a variety of medical applications. Depicts the latest advances in using calcium phosphates in bone regeneration and tissue engineering Includes the latest generation of regenerative biomaterials with an integrated perspective combining both research and clinical issues Provides an understanding of the clinical targets and requirements for regenerative medicine Detailing fundamentals through applications, this book helps biomaterials researchers to better understand the clinical targets and requirements for use of these materials for optimal synthesis and development.

Advances in Calcium Phosphate Biomaterials

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Publisher : Springer Science & Business
ISBN 13 : 3642539807
Total Pages : 559 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Advances in Calcium Phosphate Biomaterials by : Besim Ben-Nissan

Download or read book Advances in Calcium Phosphate Biomaterials written by Besim Ben-Nissan and published by Springer Science & Business. This book was released on 2014-04-17 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia

Developments and Applications of Calcium Phosphate Bone Cements

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Publisher : Springer
ISBN 13 : 9811059756
Total Pages : 632 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Developments and Applications of Calcium Phosphate Bone Cements by : Changsheng Liu

Download or read book Developments and Applications of Calcium Phosphate Bone Cements written by Changsheng Liu and published by Springer. This book was released on 2017-10-20 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a state-of-the-art review of the latest advances in developing calcium- phosphate bone cements and their applications. It covers the synthesis methods, characterization approaches, material modification and novel binders, as well as the fabrication technologies of calcium-phosphate-based biomaterials in regenerative medicine and their clinical applications. It also highlights methodologies for fabricating scaffolds, biofunctional surfaces/interfaces and subsequently modulating the host response to implantable/injectable materials, and integrates a series of discussions and insights into calcium-phosphate cements and constructs in bone regenerative medicine. As such, the book not only covers the fundamentals but also opens new avenues for meeting future challenges in research and clinical applications.

Thin Calcium Phosphate Coatings for Medical Implants

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Publisher : Springer Science & Business Media
ISBN 13 : 0387777199
Total Pages : 337 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Thin Calcium Phosphate Coatings for Medical Implants by : Betty León

Download or read book Thin Calcium Phosphate Coatings for Medical Implants written by Betty León and published by Springer Science & Business Media. This book was released on 2009-06-29 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents for the first time, the scattered novel results that have been achieved in very recent years in study on various thin calcium phosphate coatings produced by very diverse techniques. The comparison of thin calcium phosphate coatings with the thick plasma-sprayed ones is also included in the book. Readers will find a comprehensive book reviewing the state-of-the-art of the field with critical assessment of the achievements of the different preparation techniques.

Calcium Orthophosphates

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Publisher : CRC Press
ISBN 13 : 9814364177
Total Pages : 863 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Calcium Orthophosphates by : Sergey V. Dorozhkin

Download or read book Calcium Orthophosphates written by Sergey V. Dorozhkin and published by CRC Press. This book was released on 2012-06-04 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha

Calcium Phosphate Nanocoatings for Bone Regeneration

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Publisher : Springer Nature
ISBN 13 : 9819955068
Total Pages : 89 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Calcium Phosphate Nanocoatings for Bone Regeneration by : Andy H. Choi

Download or read book Calcium Phosphate Nanocoatings for Bone Regeneration written by Andy H. Choi and published by Springer Nature. This book was released on 2023-09-11 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides in-depth assessment on the latest clinical advances in multifunctional calcium phosphate nanocoatings and its influence on bone regeneration and early healing following implantation. A greater emphasis will be placed on the use of nanocomposite coatings to deliver biological materials such as mesenchymal stem cells, growth factors, bone morphogenetic and extracellular matrix proteins, and pharmaceutics such as simvastatin to improve and promote bone growth as well as reducing the timeframe needed for implant integration in both healthy and osteoporotic patients. The content of the book caters to clinical practitioners and researchers working in the field of biomaterials for bone regeneration.

Novel Advances and Approaches in Biomedical Materials Based on Calcium Phosphates

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Publisher : MDPI
ISBN 13 : 3039282646
Total Pages : 176 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Novel Advances and Approaches in Biomedical Materials Based on Calcium Phosphates by : Michael R. Mucalo

Download or read book Novel Advances and Approaches in Biomedical Materials Based on Calcium Phosphates written by Michael R. Mucalo and published by MDPI. This book was released on 2020-12-15 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research into the use of calcium phosphates in the development and clinical application of biomedical materials has been a significantly diverse activity conducted by a wide range of scientists, engineers, and medical practitioners, among others. The field of research in this area can, hence, be truly defined as interdisciplinary, and much interesting work leading to imaginative and innovative solutions for the improvement of health outcomes continues to be generated. It has been the intention of this Special Issue to summarise a number of current topical research advances in this area, as well as to review the important area of calcium phosphate-based biomaterials, namely, composites of hydroxyapatite with carbon-based materials. The scientific papers contained in this Special Issue report on advances in the areas of dental-based materials science, bone cements, use of biomaterials created from natural sources, influences of added agents such as adipose stem cells and statins on bioactivity as well as surface influences on electrical potential of biomaterials and uses of glow discharge methods to remove impurities from biomaterial surfaces.

Biomaterials for Bone, Regenerative Medicine

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Publisher : Trans Tech Publications Ltd
ISBN 13 : 3038134422
Total Pages : 210 pages
Book Rating : 4.0/5 (381 download)

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Book Synopsis Biomaterials for Bone, Regenerative Medicine by : Nandyala Sooraj Hussain

Download or read book Biomaterials for Bone, Regenerative Medicine written by Nandyala Sooraj Hussain and published by Trans Tech Publications Ltd. This book was released on 2010-03-01 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume is indexed by Thomson Reuters BCI (WoS). The aim of “Biomaterials for Bone Regenerative Medicine” is to review extensively the latest developments in Biomaterials and their application to bone regeneration in vivo. Indeed, research on biomaterials and their novel applications is essential because of the health issues related to the aging population. A wide range of worldwide investigations is being undertaken by eminent scholars in order to develop further innovative materials for next-generation applications. In future, it is expected that a tissue engineering approach, associating novel biomaterials with stem cells, will be available for all types of bone defect.

Calcium Phosphate Based Bioceramics for Bone Tissue Engineering

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Publisher : Trans Tech Publications Ltd
ISBN 13 : 3038132373
Total Pages : 170 pages
Book Rating : 4.0/5 (381 download)

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Book Synopsis Calcium Phosphate Based Bioceramics for Bone Tissue Engineering by : Sergey Barinov

Download or read book Calcium Phosphate Based Bioceramics for Bone Tissue Engineering written by Sergey Barinov and published by Trans Tech Publications Ltd. This book was released on 2008-10-02 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering is a new biotechnology that combines various aspects of medicine, biology and engineering, in order to produce, repair or replace human tissue. It is therefore easy to grasp the potential of these new therapies in helping to improve the quality-of-life of patients suffering from rare diseases. Typically, bone tissue engineering approaches foresee the use of scaffolding material combined with tissue cells. An advanced scaffolding material for tissue engineering must exhibit high quality, reliability, sustainability and cost-effectiveness throughout the individual’s life and provide new advanced levels of medical assistance in therapy and surgery. One particular requirement of bone tissue engineering is that the scaffold should be porous because, in that form, large numbers of cells can be incorporated.

Bone Repair Biomaterials

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Publisher : Woodhead Publishing
ISBN 13 : 0081024525
Total Pages : 506 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Bone Repair Biomaterials by : Kendell Pawelec

Download or read book Bone Repair Biomaterials written by Kendell Pawelec and published by Woodhead Publishing. This book was released on 2018-11-29 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites

Characterization and Performance of Calcium Phosphate Coatings for Implants

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Publisher : ASTM International
ISBN 13 : 0803118546
Total Pages : 222 pages
Book Rating : 4.8/5 (31 download)

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Book Synopsis Characterization and Performance of Calcium Phosphate Coatings for Implants by : Emanuel Horowitz

Download or read book Characterization and Performance of Calcium Phosphate Coatings for Implants written by Emanuel Horowitz and published by ASTM International. This book was released on 1994 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioceramics Calcium Phosphate

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Publisher : CRC Press
ISBN 13 : 1351087037
Total Pages : 165 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Bioceramics Calcium Phosphate by : K. de Groot

Download or read book Bioceramics Calcium Phosphate written by K. de Groot and published by CRC Press. This book was released on 2018-01-18 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first chapters are fundamental, in that the physical chemistry of calcium phosphate salts is discussed, along with mineralization (with emphasis on teeth) and remodelling of mineralized tissues. Thereafter follows a treatment of the influence of implants o surrounding hard tissues. This topic is followed by a chapter on preparation methods and biomechanical and biological aspects of calcium phosphate implants. In conclusion, two chapters are devoted to (possible) dental and medical applications. It is hoped that basic researchers can use the book in their efforts to improve this promising class of materials further, and that clinicians are inspired to define further possibilities and at least as important limitations.

Biomineralization and Biomaterials

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Publisher : Woodhead Publishing
ISBN 13 : 1782423567
Total Pages : 504 pages
Book Rating : 4.7/5 (824 download)

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Book Synopsis Biomineralization and Biomaterials by : Conrado Aparicio

Download or read book Biomineralization and Biomaterials written by Conrado Aparicio and published by Woodhead Publishing. This book was released on 2015-09-28 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance. Provides a thorough overview of the biomineralization process Presents the most recent information on the natural process by which crystals in tissues form into inorganic structures such as bone, teeth, and other natural mineralized tissues Investigates methods for improving mineralization Explores new techniques that will help improve the biomimetic process

Octacalcium Phosphate Biomaterials

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Publisher : Woodhead Publishing
ISBN 13 : 0081025122
Total Pages : 374 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Octacalcium Phosphate Biomaterials by : Gerard Insley

Download or read book Octacalcium Phosphate Biomaterials written by Gerard Insley and published by Woodhead Publishing. This book was released on 2019-11-20 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry. OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material. Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties Presents the clinical potential of octacalcium phosphate biomaterials Provides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration

Translating Biomaterials for Bone Graft

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Publisher : CRC Press
ISBN 13 : 1315363518
Total Pages : 398 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Translating Biomaterials for Bone Graft by : Joo L. Ong

Download or read book Translating Biomaterials for Bone Graft written by Joo L. Ong and published by CRC Press. This book was released on 2017-01-06 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.

Calcium Phosphate-based Resorbable Biomaterials for Bone Regeneration

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Publisher :
ISBN 13 :
Total Pages : 458 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis Calcium Phosphate-based Resorbable Biomaterials for Bone Regeneration by : Daniel O. Costa

Download or read book Calcium Phosphate-based Resorbable Biomaterials for Bone Regeneration written by Daniel O. Costa and published by . This book was released on 2012 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone defects are a prevalent problem in orthopedics and dentistry. Calcium phosphate-based coatings and nanocomposites offer unique solutions towards producing scaffolds with suitable physical, mechanical and biological properties for bone regeneration. We developed a novel method to synthesize hydroxyapatite (HA) particles with high aspect ratio using sol-gel chemistry and hydrothermal treatment. We obtained tunable pure-phase carbonated-HA in the form of micro/nanorods and nanowires (diameters 25-800 nm). To mimic the structure of bone, HA nanowires were homogenously mixed within poly( -caprolactone) (PCL) to produce nanocomposites with improved mechanical properties as determined by uniaxial tensile testing. Surface chemistry and topography of biomaterials play prominent roles in regulating cell adhesion and differentiation. Bone-like apatite coatings, produced by incubating materials in a simulated body fluid (SBF), improve the osteoconductivity of scaffold materials. However, few studies have controlled the surface topography of biomimetic HA. We assessed the effect of SBF ion concentration and soaking time on the surface properties of apatite coatings. Calcium phosphates such as carbonated-HA with similar chemical composition and stiffness were deposited onto PCL films. Characterization of these coatings revealed an increase in topographical complexity and surface roughness with increasing ion concentration of SBF and soaking time. To investigate their potential application in bone regeneration, we studied the influence of topography of biomimetic HA coatings on the behavior of osteoblasts and osteoclasts in vitro. Osteoblast attachment and differentiation were significantly greater iv when cultured on rougher HA surfaces (Ra 2̃ m) than on smoother topographies (Ra 1̃ m). In contrast, activity of tartrate-resistant acid phosphatase (an osteoclast marker) was greater on smoother than on rougher HA surfaces. Furthermore, osteoclastic resorption lacunae were found exclusively on smoother HA coatings. Inhibition of resorption on rougher HA surfaces was associated with disruption of filamentous actin sealing zones. In conclusion, HA coatings can be prepared with different topographies, which regulate responses of osteoblasts and osteoclasts. Thus, it may be possible to design HA-polymer composites and HA-coated polymers with physical, mechanical and biological properties suitable for tissue engineering. By modulating topography, rates of bone formation and biodegradation could be tailored for specific applications in orthopedics and dentistry.