Protein Degradation with New Chemical Modalities

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839160772
Total Pages : 382 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Protein Degradation with New Chemical Modalities by : Hilmar Weinmann

Download or read book Protein Degradation with New Chemical Modalities written by Hilmar Weinmann and published by Royal Society of Chemistry. This book was released on 2020-10-07 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research. In particular, the development of proteolysis targeting chimera (PROTACs) as potential drugs capable of recruiting target proteins to the cellular quality control machinery for elimination has opened new avenues to address traditionally ‘difficult to target’ proteins. This book provides a comprehensive overview from the leading academic and industrial experts on recent developments, scope and limitations in this dynamically growing research area; an ideal reference work for researchers in drug discovery and chemical biology as well as advanced students.

Biochemicals, Reagents & Kits for Life Science Research

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Publisher :
ISBN 13 :
Total Pages : 3104 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Biochemicals, Reagents & Kits for Life Science Research by : Sigma Chemical Company

Download or read book Biochemicals, Reagents & Kits for Life Science Research written by Sigma Chemical Company and published by . This book was released on 2006 with total page 3104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Goliath's Revenge

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119541875
Total Pages : 294 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Goliath's Revenge by : Todd Hewlin

Download or read book Goliath's Revenge written by Todd Hewlin and published by John Wiley & Sons. This book was released on 2019-02-12 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Harness your company’s incumbent advantages to win the digital disruption game Goliath’s Revenge is the practical guide for how executives and aspiring leaders of established companies can run the Silicon Valley playbook for themselves and capitalize on digital disruption. Technologies like artificial intelligence, robotics, internet of things, blockchain, and immersive experiences are changing the basis of competition in every industry. New competitors are emerging while traditional ones are falling behind. Periods of intense change provide remarkable opportunities. Goliath’s Revenge delivers an insider’s view of how industry leaders like General Motors, NASA, The Weather Channel, Hitachi, Mastercard, Proctor & Gamble, Penn Medicine, Discovery, and Cisco are accelerating innovation, building new skills, and disrupting themselves to come out stronger in this post-digital age. Learn how to leverage your company’s scale, reach, data, and expertise to launch breakthrough offerings that fend off attackers and secure your position as a future industry leader. Using real success cases and recommendations, this invaluable resource shows how to realign your business model, reset your talent development priorities, and retake market share lost to digital-ready competitors. Drawing from extensive experience in digital transformation, leadership development, and strategic planning, the authors show how established companies can switch from defense to offense to thrive in this new digital environment. Learn the six new rules that separate winners from losers in the age of digital disruption Prioritize your innovation investments to rebuild your competitive moat Employ smart cannibalization to defend your core business Deliver step-change customer outcomes to grow into adjacent markets Reframe your purpose and make talent the centerpiece of your digital innovation strategy Goliath’s Revenge is a must-read for business leaders and innovators in small, mid-sized, and large organizations trying to win the digital disruption game. This book helps you reset both your company strategy and professional development priorities for long-term success.

The Directory of Executive Recruiters, 2002

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Author :
Publisher : Kennedy Information
ISBN 13 : 9781885922779
Total Pages : 1204 pages
Book Rating : 4.9/5 (227 download)

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Book Synopsis The Directory of Executive Recruiters, 2002 by : Kennedy Information, Inc

Download or read book The Directory of Executive Recruiters, 2002 written by Kennedy Information, Inc and published by Kennedy Information. This book was released on 2001-08 with total page 1204 pages. Available in PDF, EPUB and Kindle. Book excerpt: The paperback edition of The Directory of Executive Recruiters is a quick but thorough reference for career changers and job-seekers to contact search firms that match their areas of expertise. Using the same database as the Corporate Edition above, it concentrates on North American firms. Internal information such as firm revenues, number of recruiters, etc., is not included. Introductory material helps guide job-seeker expectations with strategies for using recruiters as part of overall career management. "Anyone looking to turn headhunters' heads should have a copy of the Directory." --William Flanagan, Senior Editor, Forbes

Business World

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Publisher :
ISBN 13 :
Total Pages : 1238 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Business World by :

Download or read book Business World written by and published by . This book was released on 2005-02 with total page 1238 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Directory of Executive Recruiters

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Author :
Publisher :
ISBN 13 : 9781885922816
Total Pages : 1394 pages
Book Rating : 4.9/5 (228 download)

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Book Synopsis The Directory of Executive Recruiters by : Kennedy Information Staff

Download or read book The Directory of Executive Recruiters written by Kennedy Information Staff and published by . This book was released on 2001-12 with total page 1394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Known since 1971 as the "Red Book," The Directory of Executive Recruiters has been called "the bible" of the industry by CNBC and Sylvia Porter. It is the largest continuously updated recruiter database in the world. This jumbo hardcover edition is specially designed to help corporate buyers of search services make informed decisions on which recruiting firm would best suit their hiring needs. It is also useful to search providers for competitive intelligence, acquisitions, and partnerships. The Directory lists over 8,000 offices of 5,700 search firms in the U.S., Canada and Mexico and contain detailed information on each firm: street addresses, phone numbers, fax numbers, e-mail and web addresses, plus function and industry specialties. It is comprehensively indexed by function, industry, specialty and geographic location. The unique specialty index has 565 niche categories with the names and company affiliations of over 14,000 recruiters. In addition, the Corporate Edition reports firm revenues, number of recruiters and year founded and lists full contact information for international branch offices. It also contains a key contact index. Introductory pages give expert advice to corporate hirers on choosing and using executive search firms. "The Directory of Executive Recruiters is one of the most popular reference books in libraries nationwide." -- Lynne M Oliver, Reference Librarian, Morris County (NJ) Library.

Human Systems Management: Integrating Knowledge, Management And Systems

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Author :
Publisher : World Scientific
ISBN 13 : 9814488844
Total Pages : 484 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Human Systems Management: Integrating Knowledge, Management And Systems by : Milan Zeleny

Download or read book Human Systems Management: Integrating Knowledge, Management And Systems written by Milan Zeleny and published by World Scientific. This book was released on 2005-09-01 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Systems Management is an important work that integrates knowledge, management and systems into a unified world of thinking and action in business, decision-making and economics. It presents a modern synthesis of the fields of knowledge management, systems science and human organization. A biological rather than mechanistic perspective pervades the text. New and original ideas and approaches are presented with the simplicity and clarity typical of the well-known author.

YOUMARES 8 – Oceans Across Boundaries: Learning from each other

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Author :
Publisher : Springer
ISBN 13 : 3319932845
Total Pages : 259 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis YOUMARES 8 – Oceans Across Boundaries: Learning from each other by : Simon Jungblut

Download or read book YOUMARES 8 – Oceans Across Boundaries: Learning from each other written by Simon Jungblut and published by Springer. This book was released on 2018-08-29 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents the proceedings volume of the YOUMARES 8 conference, which took place in Kiel, Germany, in September 2017, supported by the German Association for Marine Sciences (DGM). The YOUMARES conference series is entirely bottom-up organized by and for YOUng MARine RESearchers. Qualified early career scientists moderated the scientific sessions during the conference and provided literature reviews on aspects of their research field. These reviews and the presenters’ conference abstracts are compiled here. Thus, this book discusses highly topical fields of marine research and aims to act as a source of knowledge and inspiration for further reading and research.

Python for Biologists

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Author :
Publisher : Createspace Independent Publishing Platform
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Python for Biologists by : Martin Jones

Download or read book Python for Biologists written by Martin Jones and published by Createspace Independent Publishing Platform. This book was released on 2013 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Python for biologists is a complete programming course for beginners that will give you the skills you need to tackle common biological and bioinformatics problems.

The Directory of Executive Recruiters

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Author :
Publisher :
ISBN 13 :
Total Pages : 1322 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis The Directory of Executive Recruiters by :

Download or read book The Directory of Executive Recruiters written by and published by . This book was released on 2000 with total page 1322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide is designed for businesses seeking professional assistance in filling key positions. Material is arranged by method of payment (retainer or contingency), by geographical area, and by alphabetical list of key principal officers of recruiting firms.

Practical Aspects of Signal Detection in Pharmacovigilance

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Author :
Publisher : Cioms
ISBN 13 : 9789290360827
Total Pages : 0 pages
Book Rating : 4.3/5 (68 download)

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Book Synopsis Practical Aspects of Signal Detection in Pharmacovigilance by : Council for International Organizations of Medical Sciences (CIOMS)

Download or read book Practical Aspects of Signal Detection in Pharmacovigilance written by Council for International Organizations of Medical Sciences (CIOMS) and published by Cioms. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years public expectations for rapid identification and prompt management of emerging drug safety issues have grown swiftly. Over a similar timeframe, the move from paper-based adverse event reporting systems to electronic capture and rapid transmission of data has resulted in the accrual of substantial datasets capable of complex analysis and querying by industry, regulators and other public health organizations. These two drivers have created a fertile environment for pharmacovigilance scientists, information technologists and statistical experts, working together, to deliver novel approaches to detect signals from these extensive and quickly growing datasets, and to manage them appropriately. In following this exciting story, this report looks at the practical consequences of these developments for pharmacovigilance practitioners. The report provides a comprehensive resource for those considering how to strengthen their pharmacovigilance systems and practices, and to give practical advice. But the report does not specify instant solutions. These will inevitably be situation specific and require careful consideration taking into account local needs. However, the CIOMS Working Group VIII is convinced that the combination of methods and a clear policy on the management of signals will strengthen current systems. Finally, in looking ahead, the report anticipates a number of ongoing developments, including techniques with wider applicability to other data forms than individual case reports. The ultimate test for pharmacovigilance systems is the demonstration of public health benefit and it is this test which signal detection methodologies need to meet if the expectations of all stakeholders are to be fulfilled.

Configuring the Networked Self

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Author :
Publisher : Yale University Press
ISBN 13 : 0300125437
Total Pages : 351 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis Configuring the Networked Self by : Julie E. Cohen

Download or read book Configuring the Networked Self written by Julie E. Cohen and published by Yale University Press. This book was released on 2012-01-24 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The legal and technical rules governing flows of information are out of balance, argues Julie E. Cohen in this original analysis of information law and policy. Flows of cultural and technical information are overly restricted, while flows of personal information often are not restricted at all. The author investigates the institutional forces shaping the emerging information society and the contradictions between those forces and the ways that people use information and information technologies in their everyday lives. She then proposes legal principles to ensure that people have ample room for cultural and material participation as well as greater control over the boundary conditions that govern flows of information to, from, and about them.

Illinois Services Directory

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Publisher :
ISBN 13 :
Total Pages : 2170 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Illinois Services Directory by :

Download or read book Illinois Services Directory written by and published by . This book was released on 2008 with total page 2170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioinformatics for Beginners

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Author :
Publisher : Elsevier
ISBN 13 : 0124105106
Total Pages : 238 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Bioinformatics for Beginners by : Supratim Choudhuri

Download or read book Bioinformatics for Beginners written by Supratim Choudhuri and published by Elsevier. This book was released on 2014-05-09 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. - Avoids non-essential coverage, yet fully describes the field for beginners - Explains the molecular basis of evolution to place bioinformatic analysis in biological context - Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools - Contains over 100 figures that aid in concept discovery and illustration

Principles and Techniques of Biochemistry and Molecular Biology

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Publisher : Cambridge University Press
ISBN 13 : 0521516358
Total Pages : 769 pages
Book Rating : 4.5/5 (215 download)

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Book Synopsis Principles and Techniques of Biochemistry and Molecular Biology by : Keith Wilson

Download or read book Principles and Techniques of Biochemistry and Molecular Biology written by Keith Wilson and published by Cambridge University Press. This book was released on 2010-03-04 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniquely integrates the theory and practice of key experimental techniques for bioscience undergraduates. Now includes drug discovery and clinical biochemistry.

Implementing CDISC Using SAS

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Publisher : SAS Institute
ISBN 13 : 1642952419
Total Pages : 294 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Implementing CDISC Using SAS by : Chris Holland

Download or read book Implementing CDISC Using SAS written by Chris Holland and published by SAS Institute. This book was released on 2019-05-30 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades researchers and programmers have used SAS to analyze, summarize, and report clinical trial data. Now Chris Holland and Jack Shostak have updated their popular Implementing CDISC Using SAS, the first comprehensive book on applying clinical research data and metadata to the Clinical Data Interchange Standards Consortium (CDISC) standards. Implementing CDISC Using SAS: An End-to-End Guide, Revised Second Edition, is an all-inclusive guide on how to implement and analyze the Study Data Tabulation Model (SDTM) and the Analysis Data Model (ADaM) data and prepare clinical trial data for regulatory submission. Updated to reflect the 2017 FDA mandate for adherence to CDISC standards, this new edition covers creating and using metadata, developing conversion specifications, implementing and validating SDTM and ADaM data, determining solutions for legacy data conversions, and preparing data for regulatory submission. The book covers products such as Base SAS, SAS Clinical Data Integration, and the SAS Clinical Standards Toolkit, as well as JMP Clinical. Topics included in this edition include an implementation of the Define-XML 2.0 standard, new SDTM domains, validation with Pinnacle 21 software, event narratives in JMP Clinical, STDM and ADAM metadata spreadsheets, and of course new versions of SAS and JMP software. The second edition was revised to add the latest C-Codes from the most recent release as well as update the make_define macro that accompanies this book in order to add the capability to handle C-Codes. The metadata spreadsheets were updated accordingly. Any manager or user of clinical trial data in this day and age is likely to benefit from knowing how to either put data into a CDISC standard or analyzing and finding data once it is in a CDISC format. If you are one such person--a data manager, clinical and/or statistical programmer, biostatistician, or even a clinician--then this book is for you.

Biological & Agricultural Index

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Author :
Publisher :
ISBN 13 :
Total Pages : 1064 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Biological & Agricultural Index by :

Download or read book Biological & Agricultural Index written by and published by . This book was released on 1919 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: