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Download or read book Company Profiles: TAU Therapeutics LLC. written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Beller Health
Publisher : Independently Published
ISBN 13 : 9781097268511
Total Pages : 114 pages
Book Rating : 4.2/5 (685 download)
Download or read book Limbic-predominant Age-related TDP-43 Encephalopathy written by Beller Health and published by Independently Published. This book was released on 2019-05-13 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Book 9 focuses on a new dementia type, LATE, mistaken as Alzheimer's disease until now.LATE stands for Limbic-predominant age-related TDP-43 encephalopathy, the protein buildup responsible for this dementia. This book is organic, like the series, meaning we never consider our books as finished. Science evolves, which is why our books go through continuous updates. Since LATE is a new dementia classification, we expect continuous further information to emerge. Watch Amazon alerts for potential digital updates. We provide free digital copies on all paperback purchases, so everybody receives free updates.
Author : Jerry J. Buccafusco
Publisher : CRC Press
ISBN 13 : 1420041819
Total Pages : 341 pages
Book Rating : 4.4/5 (2 download)
Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Author : John O'Brien
Publisher : CRC Press
ISBN 13 : 0203313909
Total Pages : 286 pages
Book Rating : 4.2/5 (33 download)
Download or read book Dementia with Lewy Bodies written by John O'Brien and published by CRC Press. This book was released on 2005-11-29 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. With huge progress having been made over the last decade in terms of the disorder
Author : Charlotte E. Teunissen
Publisher : Humana
ISBN 13 : 9781071613214
Total Pages : 236 pages
Book Rating : 4.6/5 (132 download)
Download or read book Cerebrospinal Fluid Biomarkers written by Charlotte E. Teunissen and published by Humana. This book was released on 2022-05-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.
Author :
Publisher :
ISBN 13 :
Total Pages : 654 pages
Book Rating : 4.:/5 (89 download)
Download or read book GEN Guide to Biotechnology Companies written by and published by . This book was released on 1998 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William Kremen
Publisher : Frontiers Media SA
ISBN 13 : 2832509398
Total Pages : 160 pages
Book Rating : 4.8/5 (325 download)
Download or read book The importance of cognitive practice effects in aging neuroscience written by William Kremen and published by Frontiers Media SA. This book was released on 2022-12-19 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Firas H. Kobeissy
Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.4/5 (665 download)
Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
Author : Amit Alexander
Publisher : Springer Nature
ISBN 13 : 9819728592
Total Pages : 398 pages
Book Rating : 4.8/5 (197 download)
Download or read book Application of Nanocarriers in Brain Delivery of Therapeutics written by Amit Alexander and published by Springer Nature. This book was released on with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Heiko Braak
Publisher : Springer
ISBN 13 : 3319126792
Total Pages : 168 pages
Book Rating : 4.3/5 (191 download)
Download or read book Neuroanatomy and Pathology of Sporadic Alzheimer's Disease written by Heiko Braak and published by Springer. This book was released on 2014-12-11 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail
Author : Jeffrey Cummings
Publisher : Cambridge University Press
ISBN 13 : 1108838669
Total Pages : 575 pages
Book Rating : 4.1/5 (88 download)
Download or read book Alzheimer's Disease Drug Development written by Jeffrey Cummings and published by Cambridge University Press. This book was released on 2022-03-31 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Author : Marinos C. Dalakas
Publisher : Butterworth-Heinemann
ISBN 13 : 1483163040
Total Pages : 362 pages
Book Rating : 4.4/5 (831 download)
Download or read book Polymyositis and Dermatomyositis written by Marinos C. Dalakas and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymyositis and Dermatomyositis provides extensive information regarding Polymyositis and Dermatomyositis (PM/DM), which is described as a heterogeneous disease complex. This book is divided into four sections: Part I (Clinical Features) covers the classification of PM/DM, details of the clinical presentation, and the disease's association with the other connective tissue disorders and malignancies. Part II (Etiology and Mechanisms) covers advances in the immunopathology and viral etiology of PM/DM along with a frequently recognized entity: inclusion body myositis. Part III (Diagnosis and Treatment) covers the histologic, muscle enzyme histochemical, electron microscopic, and resin histology features of PM/DM along with those electromyographic features that could help make a more accurate diagnosis. Part IV (Overview) summarizes the issues that may not have been clear and highlights differing and unsettled views or present available data. This text is directed to clinicians in private practice or in academic institutions concerned with PM/DM patients, including neurologists, rheumatologists, pediatricians, dermatologists, physiatrists, and neuromuscular investigators. This book is intended as well for neuromuscular pathologists who interpret muscle biopsy specimens and electromyographers who perform EMG studies to help determine the clinical diagnosis. Researchers in immunology and immunopathology of neuromuscular diseases will find discussions in this book invaluable.
Author : Joachim Klement
Publisher : CFA Institute Research Foundation
ISBN 13 : 1944960473
Total Pages : 150 pages
Book Rating : 4.9/5 (449 download)
Download or read book Risk Profiling and Tolerance: Insights for the Private Wealth Manager written by Joachim Klement and published by CFA Institute Research Foundation. This book was released on 2018-05-01 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: If risk aversion and willingness to take on risk are driven by emotions and we as humans are bad at correctly identifying them, the finance profession has a serious challenge at hand—how to reliably identify the individual risk profile of a retail investor or high-net-worth individual. In this series of CFA Institute Research Foundation briefs, we have asked academics and practitioners to summarize the current state of knowledge about risk profiling in different key areas.
Author : Jesus Avila
Publisher : Frontiers E-books
ISBN 13 : 288919261X
Total Pages : 114 pages
Book Rating : 4.8/5 (891 download)
Download or read book Tau oligomers written by Jesus Avila and published by Frontiers E-books. This book was released on 2014-08-18 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.
Author : Tom Dening
Publisher : Oxford University Press
ISBN 13 : 0192534149
Total Pages : 912 pages
Book Rating : 4.1/5 (925 download)
Download or read book Oxford Textbook of Old Age Psychiatry written by Tom Dening and published by Oxford University Press. This book was released on 2020-10-29 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Textbook of Old Age Psychiatry, Third Edition, has been thoroughly updated to keep pace with the developments that have taken place in old age psychiatry since publication of the Second Edition in 2013, including the publication of the DSM-5/ICD-11 classification criteria. The Third Edition also includes new chapters on the ageing brain; the experience of dementia; carers' issues; biomarkers; and old age psychiatry in low- and middle-income countries. This new edition introduces two new co-editors, Robert Stewart, Professor of Psychiatric Epidemiology & Clinical Informatics at King's College London (and a Co-Editor of Practical Psychiatric Epidemiology), and John-Paul Taylor, Professor of Translational Dementia Research at Newcastle University. Part of the authoritative Oxford Textbooks in Psychiatry series, this comprehensive resource is an essential reference for old age psychiatrists, geriatricians, and other clinicians who are interested in the mental health care of older people.
Author : Theresa Raphael-Grimm, PhD, CNS
Publisher : Springer Publishing Company
ISBN 13 : 0826110568
Total Pages : 202 pages
Book Rating : 4.8/5 (261 download)
Download or read book The Art of Communication in Nursing and Health Care written by Theresa Raphael-Grimm, PhD, CNS and published by Springer Publishing Company. This book was released on 2014-10-10 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: A handy guide to tackling difficult patient and professional interactions with confidence and compassion In this age of increasing reliance on technology, it is essential that the fundamentals of compassion and good communication—the art of patient care—remain at the heart of health care. This clear, concise guide to professional communication strategies helps nurses and other health care clinicians to build effective patient relationships and navigate a wide variety of difficult patient and professional interactions. Written by a practicing psychotherapist who has devoted nearly 30 years of study to clinician—patient relationships, the book tackles such complex issues as dealing with demanding patients, maintaining professional boundaries, overcoming biases and stereotypes, managing clinician emotions, communicating bad news, challenging a colleague’s clinical opinion, and other common scenarios. The book guides the reader through a conceptual framework for building effective relationships that is based on the principles of mindfulness. These principles are embedded in discussions of the fundamental elements of interpersonal effectiveness, such as hope, empathy, and listening. Chapters apply mindfulness principles to specific challenging situations with concrete examples that describe effective clinical behaviors as well as situations depicting pitfalls that may impede compassionate care. From a focus on everyday manners in difficult situations to beneficial approaches with challenging populations, the guide helps health care professionals confidently resolve common problems. Brief, to-the-point chapters help clinicians channel their clinical knowledge and good intentions into caring behaviors that allow the patient to more fully experience empathy and compassion. With the guiding theme of “using words as precision instruments,” this is a resource that will be referred to again and again. Key Features: • Helps health care professionals and nurses communicate effectively in challenging clinical and professional situations • Uses the principles of mindfulness to build satisfying relationships and resolve problems • Addresses such difficult issues as demanding patients, maintaining boundaries, overcoming biases, managing clinician emotions, and much more • Provides special tips for communicating with family members and caregivers • Authored by a practicing psychotherapist specializing in clinician—patient relationships for nearly 30 years
Author : C.A. Raji
Publisher : IOS Press
ISBN 13 : 1643684930
Total Pages : 674 pages
Book Rating : 4.6/5 (436 download)
Download or read book Handbook of Prevention and Alzheimer’s Disease written by C.A. Raji and published by IOS Press. This book was released on 2024-02-20 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of modifiable risk factors associated with the disease has been present from the outset. Thus, the idea of preventing AD is not new, with reference to strategies noted as early as the 1990s. This subfield of AD research has matured in recent years, with the number of modifiable risk factors – the AD preventome – rising from the 7 initially identified to the current 12, with an estimated contribution to dementia cases worldwide of about 40%. This book, the Handbook of Prevention and Alzheimer’s Disease, introduces physicians, scientists, and other stakeholders to this subfield of AD research. It investigates the AD preventome, which will continue to expand as the understanding of new factors and related biomarkers is refined. Optimizing this preventome leads to an improvement in overall brain health, an outcome which reduces the risk of developing AD and improves quality of life. The book goes on to examine other domains of prevention, from vascular risk factors to social engagement and from sleep health to spirituality. If the journey to end AD can be likened to a long and arduous challenge, understanding every possible part of the overall toolkit of approaches for disease prevention and intervention is essential. Together with its companion volume on intervention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: White matter tracts showing sex differences in connectivity in men versus women as a function of increasing body mass index. Reprinted with permission from Rahmani F, Wang Q, McKay NS, Keefe S, Hantler N, Hornbeck R, Wang Y, Hassenstab J, Schindler S, Xiong C, Morris JC, Benzinger TLS, Raji CA. Sex-Specific Patterns of Body Mass Index Relationship with White Matter Connectivity. J Alzheimers Dis. 2022;86(4):1831-1848. doi: 10.3233/JAD-215329. PMID: 35180116; PMCID: PMC9108572.
