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Author :
Publisher :
ISBN 13 :
Total Pages : 2164 pages
Book Rating : 4.3/5 (91 download)
Download or read book LexisNexis Corporate Affiliations written by and published by . This book was released on 2008 with total page 2164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : M.A. Hayat
Publisher : Springer Science & Business Media
ISBN 13 : 9400729928
Total Pages : 445 pages
Book Rating : 4.4/5 (7 download)
Download or read book Stem Cells and Cancer Stem Cells, Volume 6 written by M.A. Hayat and published by Springer Science & Business Media. This book was released on 2012-02-29 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The difference among pluripotent stem cells, multipotent stem cells, and unipotent stem cells is pointed out. Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: human embryonic stem cells, human mesenchymal stem cells, germ cell-derived pluripotent stem cells, induced pluripotent stem cells, human umbilical cord blood-derived stem cells, breast tumor stem cells,and hematopoietic stem cells. Because of the potential of human embryonic stem cells to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential. Because of their pluripotency, these cells have been used in various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. The formation of embryoid bodies, which are three-dimensional aggregates of embryonic stem cells, is explained as this is the first step in cell differentiation. Such embryoid body culture has been widely used as a trigger for the in vitro differentiation of embryonic stem cells. The basic capacity of self-renewal of human embryogenic stem cells is explained. The role of TGF-beta in the propagation of human embryonic stem cells is discussed. The differentiation of human embryonic stem cells into neurons, hepatocytes, cardiomyocytes, and retinal cells is fully explained. Donor policies for hematopoietic stem cells are also explained.
Author : Alain A. Vertes
Publisher : John Wiley & Sons
ISBN 13 : 111997139X
Total Pages : 788 pages
Book Rating : 4.1/5 (199 download)
Download or read book Stem Cells in Regenerative Medicine written by Alain A. Vertes and published by John Wiley & Sons. This book was released on 2015-12-02 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues to overcome problems in the pipeline • Written by an expert team with extensive experience in the business, basic and applied science of stem cell research This comprehensive volume is essential reading for researchers in cell biology, biotechnology, regenerative medicine, and tissue engineering, including scientists and professionals, looking to enter commercial biotechnology fields.
Author :
Publisher :
ISBN 13 :
Total Pages : 1320 pages
Book Rating : 4.:/5 ( download)
Download or read book BioScan written by and published by . This book was released on 2009 with total page 1320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Anthony Atala
Publisher : Academic Press
ISBN 13 : 0128120630
Total Pages : 438 pages
Book Rating : 4.1/5 (281 download)
Download or read book Perinatal Stem Cells written by Anthony Atala and published by Academic Press. This book was released on 2018-06-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton's jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. - Explores current clinical and pre-clinical application of stem cells derived from perinatal sources - Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment - Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells - Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells
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Publisher :
ISBN 13 :
Total Pages : 1846 pages
Book Rating : 4.3/5 (555 download)
Download or read book Mergent Corporate News Reports Monthly written by and published by . This book was released on 2008-04 with total page 1846 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lucas G. Chase
Publisher : Springer Science & Business Media
ISBN 13 : 1627032002
Total Pages : 458 pages
Book Rating : 4.6/5 (27 download)
Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.
Author :
Publisher : Academic Press
ISBN 13 : 0128130709
Total Pages : 692 pages
Book Rating : 4.1/5 (281 download)
Download or read book Platform Technologies in Drug Discovery and Validation written by and published by Academic Press. This book was released on 2017-11-21 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides. - Unique for its treatment of platform technologies for medicinal chemistry and target validation - Provides a single, rich volume that summaries a broad spectrum of expertise relevant to the field - Presents state-of-the-art summaries of platform technologies
Author : Emerson c. Perin
Publisher : Academic Press
ISBN 13 : 0128018631
Total Pages : 538 pages
Book Rating : 4.1/5 (28 download)
Download or read book Stem Cell and Gene Therapy for Cardiovascular Disease written by Emerson c. Perin and published by Academic Press. This book was released on 2015-08-21 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic. - Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials - Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis - Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI - Covers the prevailing opinions on how to harness the body's natural repair mechanisms - Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals
Author : Jim Mellon
Publisher : Harriman House Limited
ISBN 13 : 0993047823
Total Pages : 613 pages
Book Rating : 4.9/5 (93 download)
Download or read book Juvenescence written by Jim Mellon and published by Harriman House Limited. This book was released on 2017-09-25 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jeffrey Laurence
Publisher : Academic Press
ISBN 13 : 0128005521
Total Pages : 356 pages
Book Rating : 4.1/5 (28 download)
Download or read book Translating Regenerative Medicine to the Clinic written by Jeffrey Laurence and published by Academic Press. This book was released on 2015-11-18 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. - Encompasses the latest innovations and tools being used to develop regenerative medicine in the lab and clinic - Covers the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field - Contains extensive pedagogical updates aiming to improve the education of translational researchers in this field - Provides a transdisciplinary approach that supports cross-fertilization between different sub-specialties of medicine
Author :
Publisher :
ISBN 13 :
Total Pages : 182 pages
Book Rating : 4.3/5 (243 download)
Download or read book Official List of Section 13(f) Securities written by and published by . This book was released on 1981 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mariusz Z. Ratajczak
Publisher : Springer Nature
ISBN 13 : 3030312062
Total Pages : 410 pages
Book Rating : 4.0/5 (33 download)
Download or read book Stem Cells written by Mariusz Z. Ratajczak and published by Springer Nature. This book was released on 2020-01-02 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field.
Author : Richard C. Levy
Publisher :
ISBN 13 : 9781101495209
Total Pages : 488 pages
Book Rating : 4.4/5 (952 download)
Download or read book The Toy and Game Inventor's Handbook written by Richard C. Levy and published by . This book was released on 2003 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Beth H. Shaz
Publisher : Newnes
ISBN 13 : 0123977886
Total Pages : 1015 pages
Book Rating : 4.1/5 (239 download)
Download or read book Transfusion Medicine and Hemostasis written by Beth H. Shaz and published by Newnes. This book was released on 2013-05-13 with total page 1015 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals). - Updated content covers new coagulation tests, cellular therapies, and quality control issues - Easy to use, with focused, well-defined chapters in a standardized format throughout - Offers quick "cross-reference" lists at the end of each chapter - Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities
Author : Guido Moll
Publisher : Frontiers Media SA
ISBN 13 : 2889636003
Total Pages : 296 pages
Book Rating : 4.8/5 (896 download)
Download or read book Safety, Efficacy and Mechanisms of Action of Mesenchymal Stem Cell Therapies written by Guido Moll and published by Frontiers Media SA. This book was released on 2020-07-24 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Krishnarao Appasani
Publisher : Springer Science & Business Media
ISBN 13 : 1607618605
Total Pages : 632 pages
Book Rating : 4.6/5 (76 download)
Download or read book Stem Cells & Regenerative Medicine written by Krishnarao Appasani and published by Springer Science & Business Media. This book was released on 2010-11-01 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.
