Accelerating Performance

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Publisher : John Wiley & Sons
ISBN 13 : 1119147492
Total Pages : 352 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Accelerating Performance by : Colin Price

Download or read book Accelerating Performance written by Colin Price and published by John Wiley & Sons. This book was released on 2017-01-04 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transform your organization into a dynamic catalyst for success Accelerating Performance is not just another “warm and fuzzy” change management book—it's a practical, comprehensive, data-driven action plan for picking up the pace and achieving more. Co-written by one of the authors of Beyond Performance, this book draws on a combination of empirical research and decades of experience advising global companies to show you how to reduce time to value by building and changing momentum more quickly than your competitors. The META framework (short for Mobilize, Execute, and Transform with Agility) offers advice for leading change at four levels: strategy, the organization, teams, and individuals. In addition to step-by-step guidance toward assessment, planning, and implementation, the book offers: A diagnostic tool for leaders, teams, and organizations to assess their starting place, and highlight the specific areas needed to improve the ability to accelerate performance. A detailed look at the factors proven to create drag—and drive—at each of the four levels: strategy, organizations, teams, and individuals. An exploration of the 39 differentiating actions that organizations can combine as dictated by their strategy and context into a winning recipe. A closer look at the practices of 23 “superaccelerators,” a global (and perhaps unexpected) mix of companies that have demonstrated a consistent ability to accelerate performance. A single taste of success is all it takes to spark change, but the hard work of following through requires constant vigilance—and a plan. Learn how to capture that drive, bottle it, and use it to sustain motivation, inspiration, and achievement. Deliver at the highest level, and then turn around and do even better next time. Accelerating Performance gives leaders a step-by-step framework for taking action and transforming their organizations, teams, and even themselves—starting today.

Critical Theory Today

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Publisher : Routledge
ISBN 13 : 1136615563
Total Pages : 486 pages
Book Rating : 4.1/5 (366 download)

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Book Synopsis Critical Theory Today by : Lois Tyson

Download or read book Critical Theory Today written by Lois Tyson and published by Routledge. This book was released on 2012-09-10 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical Theory Today is the essential introduction to contemporary criticial theory. It provides clear, simple explanations and concrete examples of complex concepts, making a wide variety of commonly used critical theories accessible to novices without sacrificing any theoretical rigor or thoroughness. This new edition provides in-depth coverage of the most common approaches to literary analysis today: feminism, psychoanalysis, Marxism, reader-response theory, new criticism, structuralism and semiotics, deconstruction, new historicism, cultural criticism, lesbian/gay/queer theory, African American criticism, and postcolonial criticism. The chapters provide an extended explanation of each theory, using examples from everyday life, popular culture, and literary texts; a list of specific questions critics who use that theory ask about literary texts; an interpretation of F. Scott Fitzgerald's The Great Gatsby through the lens of each theory; a list of questions for further practice to guide readers in applying each theory to different literary works; and a bibliography of primary and secondary works for further reading.

Leading Pharmaceutical Innovation

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Publisher : Springer
ISBN 13 : 3319668331
Total Pages : 189 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Leading Pharmaceutical Innovation by : Oliver Gassmann

Download or read book Leading Pharmaceutical Innovation written by Oliver Gassmann and published by Springer. This book was released on 2018-05-10 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical giants have been doubling their investments in drug development, only to see new drug approvals to remain constant for the past decade. This book investigates and highlights a set of proactive strategies, aimed at generating sustainable competitive advantage for its protagonists based on value-generating business practices. We focus on three sources of pharmaceutical innovation: new management methods in the drug development pipeline, new technologies as enablers for cutting-edge R&D, and new forms of internationalisation, such as outside-in innovation in the early phases of R&D.

The Blood Brain Barrier (BBB)

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Publisher : Springer
ISBN 13 : 3662437872
Total Pages : 169 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis The Blood Brain Barrier (BBB) by : Gert Fricker

Download or read book The Blood Brain Barrier (BBB) written by Gert Fricker and published by Springer. This book was released on 2014-10-24 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Drug Transport Across the Blood-brain Barrier

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Author :
Publisher : CRC Press
ISBN 13 : 9789057020322
Total Pages : 240 pages
Book Rating : 4.0/5 (23 download)

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Book Synopsis Drug Transport Across the Blood-brain Barrier by : A.G. de Boer

Download or read book Drug Transport Across the Blood-brain Barrier written by A.G. de Boer and published by CRC Press. This book was released on 1997-04-08 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The availability of various in vitro and in vivo techniques has considerably advanced the research on drug transport and metabolism across the blood-brain barrier (BBB). These specialized and sophisticated experimental strategies are of fundamental importance if one is to gain a greater understanding of enhanced and selective drug delivery to the brain. The reader will find in this book methods for in vitro endothelial/astrocyte cell culture models, and for in vivo intracerebral microdialysis to study drug tranport across the BBB. This book, however, is not merely a laboratory manual consisting of recipes for BBB research; it permits the presentation of the different methods in fine detail, revealing tricks and short cuts that frequently do not appear in the literature. The researcher is well aware that differences (subtle or otherwise) in experimental steps used in different laboratories may influence the outcome of any particular procedure. The book also illustrates the accessibility and the application of the different methods in different species. Background information of the protocol is given in every chapter, which also contains a literature list that the reader may wish to refer to for further information. This volume will be invaluable to basic researchers as well as to those involved in the search for agents suitable for pharmaceutic intervention in the central nervous system.

Memory Traces in the Brain

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Publisher : Cambridge University Press
ISBN 13 : 9780521358675
Total Pages : 206 pages
Book Rating : 4.3/5 (586 download)

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Book Synopsis Memory Traces in the Brain by : Daniel L. Alkon

Download or read book Memory Traces in the Brain written by Daniel L. Alkon and published by Cambridge University Press. This book was released on 1987-12-25 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing the first glimpse of how associative memories are actually established in our brains, this book describes a research strategy for unravelling the mystery of memory and learning. The results of this experimental quest are described at several levels of biological complexity including animal behavior, neural systems, cellular and membrane physiology, and molecular regulation. The amply illustrated text is carefully structured to distinguish between observations and hypotheses, between attractive possibilities and empirical demonstrations. Dr Alkon progresses step-by-step through a series of experimental tests of intuitive conjectures on the nature of learning and memory. The book guides the reader through a scientific detective story that sheds new light on how we learn and how we remember.

Scientific Manpower

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Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Scientific Manpower by : National Science Foundation (U.S.)

Download or read book Scientific Manpower written by National Science Foundation (U.S.) and published by . This book was released on 1956 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes the papers of the Conference on Scientific Manpower held at the annual meeting of the American Association for the Advancement of Science, 1955-

Disorders of Protein Synthesis

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Publisher : Academic Press
ISBN 13 : 0323997813
Total Pages : 292 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Disorders of Protein Synthesis by : Rossen Donev

Download or read book Disorders of Protein Synthesis written by Rossen Donev and published by Academic Press. This book was released on 2022-09-08 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disorders of Protein Synthesis, Volume 132 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Protein Chemistry and Structural Biology series - Includes the latest information on disorders of protein synthesis

Form 10-K.

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Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.M/5 ( download)

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Book Synopsis Form 10-K. by : United States. Securities and Exchange Commission

Download or read book Form 10-K. written by United States. Securities and Exchange Commission and published by . This book was released on 1949 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Count Time Series

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Publisher : CRC Press
ISBN 13 : 9781482248050
Total Pages : 220 pages
Book Rating : 4.2/5 (48 download)

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Book Synopsis Count Time Series by : Konstantinos Fokianos

Download or read book Count Time Series written by Konstantinos Fokianos and published by CRC Press. This book was released on 2020-06-30 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Brain Targeted Drug Delivery Systems

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Publisher : Academic Press
ISBN 13 : 012814002X
Total Pages : 502 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Brain Targeted Drug Delivery Systems by : Huile Gao

Download or read book Brain Targeted Drug Delivery Systems written by Huile Gao and published by Academic Press. This book was released on 2018-09-20 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. - Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers - Discusses key points in developing brain targeting drug delivery systems - Summarizes and presents currently available strategies for brain targeting drug delivery - Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research

The Life Science Executive's Fundraising Manifesto

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Publisher : Life Science Nation
ISBN 13 : 9780990325109
Total Pages : 256 pages
Book Rating : 4.3/5 (251 download)

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Book Synopsis The Life Science Executive's Fundraising Manifesto by : Dennis Ford

Download or read book The Life Science Executive's Fundraising Manifesto written by Dennis Ford and published by Life Science Nation. This book was released on 2014-07-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: A primary objective for life science executives is raising capital. Very often, however, a lack of marketing and sales skills impedes their efforts. Focusing regionally, rather than globally, only compounds the challenge. "The Life Science Executive's Fundraising Manifesto" helps scientists understand the fundamental skills needed to brand and market their companies. It discusses how to use a consistent message to achieve compelling results from a fundraising campaign, and it teaches you how to aggregate a list of potential global investors that are a fit for your company's products and services. The book also explains how to efficiently and effectively reach out to potential investor targets, start a dialogue that fosters a relationship, and ultimately secure capital allocations. Raising capital is not a one-time event. It must be an ongoing part of your business strategy. This book reveals the expertise required to continually fundraise and bring your ideas to market. For more information about the book, please visit www.fundraisingmanifesto.com.

Nanomaterials for Drug Delivery and Therapy

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Author :
Publisher : William Andrew
ISBN 13 : 0128166290
Total Pages : 581 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanomaterials for Drug Delivery and Therapy by : Alexandru Mihai Grumezescu

Download or read book Nanomaterials for Drug Delivery and Therapy written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2019-03-14 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. - Assesses the opportunities and challenges of nanotechnology-based drug delivery systems - Explores how nanotechnology is being used to create more efficient drug delivery systems - Discusses which nanomaterials make the best drug carriers

Encyclopedia of Neuroscience

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Publisher : Springer
ISBN 13 : 9783540237358
Total Pages : 4398 pages
Book Rating : 4.2/5 (373 download)

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Book Synopsis Encyclopedia of Neuroscience by : Marc D. Binder

Download or read book Encyclopedia of Neuroscience written by Marc D. Binder and published by Springer. This book was released on 2008-10-13 with total page 4398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 5000-page masterwork is literally the last word on the topic and will be an essential resource for many. Unique in its breadth and detail, this encyclopedia offers a comprehensive and highly readable guide to a complex and fast-expanding field. The five-volume reference work gathers more than 10,000 entries, including in-depth essays by internationally known experts, and short keynotes explaining essential terms and phrases. In addition, expert editors contribute detailed introductory chapters to each of 43 topic fields ranging from the fundamentals of neuroscience to fascinating developments in the new, inter-disciplinary fields of Computational Neuroscience and Neurophilosophy. Some 1,000 multi-color illustrations enhance and expand the writings.

Myelination and Dysmyelination

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Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Myelination and Dysmyelination by : I. D. Duncan

Download or read book Myelination and Dysmyelination written by I. D. Duncan and published by . This book was released on 1990 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mucopolysaccharidoses Update (2 Volume Set)

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Publisher :
ISBN 13 : 9781536139877
Total Pages : 992 pages
Book Rating : 4.1/5 (398 download)

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Book Synopsis Mucopolysaccharidoses Update (2 Volume Set) by : Shunji Tomatsu

Download or read book Mucopolysaccharidoses Update (2 Volume Set) written by Shunji Tomatsu and published by . This book was released on with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mucopolysaccharidoses (MPS) are caused by a deficiency of lysosomal enzyme activities needed to degrade glycosaminoglycans (GAGs), which are long unbranched polysaccharides consisting of repeating disaccharides. GAGs include: Chondroitin sulfate (CS), dermatan sulfate (DS), heparan sulfate (HS), keratan sulfate (KS), and hyaluronan. Their catabolism may be blocked singly or in combination depending on the specific enzyme deficiency. There are eleven known enzyme deficiencies, resulting in seven distinct forms of MPS with a collective incidence higher than 1 in 25,000 live births. Accumulation of undegraded metabolites in lysosomes gives rise to distinct clinical syndromes. Generally, the clinical conditions progress if untreated, leading to developmental delay, systemic skeletal deformities, and early death.Other clinical features include coarse facial features, corneal clouding, recurrent ear and nose infections, inguinal and umbilical hernias, hepatosplenomegaly, heart valvular disease and skeletal deformities. Clinical features related to bone lesions may include marked short stature, cervical stenosis, pectus carinatum, small lungs, joint rigidity (but laxity for MPS IV), kyphoscoliosis, lumbar gibbus, and genu valgum. Patients with MPS are often wheelchair-bound and physical handicaps increase with age as a result of progressive skeletal dysplasia, abnormal joint mobility, and osteoarthritis. Patients may need multiple orthopedic procedures including cervical decompression and fusion, carpal tunnel release, hip reconstruction and replacement, and femoral or tibial osteotomy throughout their lifetime. Current measures to intervene in bone disease progression and CNS involvement are not perfect and palliative, and improved therapies are urgently required and are being proposed.Enzyme replacement therapy (ERT), hematopoietic stem cell transplantation (HSCT), and gene therapy are available or in development for some types of MPS. Delivery of sufficient enzymes to the brain and bones, especially avascular cartilage, to prevent or ameliorate the devastating neurological defects and skeletal dysplasias remains an unmet challenge. The use of an anti-inflammatory drug is also under clinical study. Therapies should start at a very early stage prior to irreversible bone lesion and damage, since the severity of CNS involvement and skeletal dysplasia is associated with the level of activity in a patient's daily life.For the maximum benefit of available therapies, early detection and intervention are critical. Newborn screening and diagnostic systems have been developed by using tandem mass spectrometry. We review the history of diagnosis and newborn screening as well. Overall, this book illustrates a to-date overview of the pathogenesis, diagnosis, biomarkers, screening, and updated therapies as well as their impact on MPS, including ERT, HSCT, gene therapy, and anti-inflammatory drugs. History and activities of MPS societies are also described. It is a comprehensive textbook meant to cover many areas in the field of MPS and appeals to a broad spectrum of readers including physicians, scientists, students, pharmaceutical companies, and MPS communities.

Memory's Voice

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Publisher :
ISBN 13 : 9780060984236
Total Pages : 312 pages
Book Rating : 4.9/5 (842 download)

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Book Synopsis Memory's Voice by : Daniel L. Alkon

Download or read book Memory's Voice written by Daniel L. Alkon and published by . This book was released on 1993-12-23 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of America's leading brain researchers conducts a dazzling exploration of the brain and its ability to remember. "A rich telling of the search for how the brain remembers, one of the most exciting stories now unfolding in the scientific world".--Psychology Today. Photos and drawings.