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Author : Eun Bo Shim
Publisher : Frontiers Media SA
ISBN 13 : 2889639193
Total Pages : 150 pages
Book Rating : 4.8/5 (896 download)
Download or read book Clinical Applications of Physiome Models written by Eun Bo Shim and published by Frontiers Media SA. This book was released on 2020-08-05 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chun Lok Wong
Publisher :
ISBN 13 :
Total Pages : 462 pages
Book Rating : 4.:/5 (631 download)
Download or read book From Medical Images to Individualized Cardiac Mechanics written by Chun Lok Wong and published by . This book was released on 2010 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cardiac mechanics is a branch of science that deals with forces, kinematics, and material properties of the heart, which is valuable for clinical applications and physiological studies. Although anatomical and biomechanical experiments are necessary to provide the fundamental knowledge of cardiac mechanics, the invasive nature of the procedures limits their further applicability. In consequence, noninvasive alternatives are required, and cardiac images provide an excellent source of subject-specific and in vivo information. Noninvasive and individualized cardiac mechanical studies can be achieved through coupling general physiological models derived from invasive experiments with subject-specific information extracted from medical images. Nevertheless, as data extracted from images are gross, sparse, or noisy, and do not directly provide the information of interest in general, the couplings between models and measurements are complicated inverse problems with numerous issues [that] need to be carefully considered. The goal of this research is to develop a noninvasive framework for studying individualized cardiac mechanics through systematic coupling between cardiac physiological models and medical images according to their respective merits. More specifically, nonlinear state-space filtering frameworks for recovering individualized cardiac deformation and local material parameters of realistic nonlinear constitutive laws have been proposed. to ensure the physiological meaningfulness, clinical relevance, and computational feasibility of the frameworks, five key issues have to be properly addressed, including the cardiac physiological model, the heart representation in the computational environment, the information extraction from cardiac images, the coupling between models and image information, and also the computational complexity. For the cardiac physiological model, a cardiac physiome model tailored fro cardiac image analysis has been proposed to provide a macroscopic physiological foundation for the study. For the heart representation, a meshfree method has been adopted to facilitate implementations and spatial accuracy refinements. For the information extraction from cardiac images, a registration method based on free-form deformation has been adopted for robust motion tracking. For the coupling between models and images, state-space filtering has been applied to systematically couple the models with the measurements. For the computational complexity, a mode superposition approach has been adopted to project the system into an equivalent mathematical space with much fewer dimensions for computationally feasible filtering. Experiments were performed on both synthetic and clinical data to verify the proposed frameworks."--Abstract.
Author : Davide Ambrosi
Publisher : Springer Science & Business Media
ISBN 13 : 8847019354
Total Pages : 418 pages
Book Rating : 4.8/5 (47 download)
Download or read book Modeling of Physiological Flows written by Davide Ambrosi and published by Springer Science & Business Media. This book was released on 2012-10-31 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls, and the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques, and pay constant attention to applications of relevant clinical interest. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows.
Author : Aly Farag
Publisher : Springer Science & Business Media
ISBN 13 : 0387684131
Total Pages : 563 pages
Book Rating : 4.3/5 (876 download)
Download or read book Deformable Models written by Aly Farag and published by Springer Science & Business Media. This book was released on 2007-08-21 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the complete spectrum of deformable models, its evolution as an imagery field and its use in many biomedical engineering and clinical application disciplines. It includes level sets, PDEs, curve and surface evolution and their applications in biomedical fields covering both static and motion imagery.
Author : C. D. Combs
Publisher : John Wiley & Sons
ISBN 13 : 1118952774
Total Pages : 331 pages
Book Rating : 4.1/5 (189 download)
Download or read book The Digital Patient written by C. D. Combs and published by John Wiley & Sons. This book was released on 2015-12-11 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.
Author : Aly Farag
Publisher : Springer
ISBN 13 : 9780387312019
Total Pages : 556 pages
Book Rating : 4.3/5 (12 download)
Download or read book Deformable Models written by Aly Farag and published by Springer. This book was released on 2007-08-02 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the complete spectrum of deformable models, its evolution as an imagery field and its use in many biomedical engineering and clinical application disciplines. It includes level sets, PDEs, curve and surface evolution and their applications in biomedical fields covering both static and motion imagery.
Author : Claudio Cobelli
Publisher : Academic Press
ISBN 13 : 0128158050
Total Pages : 384 pages
Book Rating : 4.1/5 (281 download)
Download or read book Introduction to Modeling in Physiology and Medicine written by Claudio Cobelli and published by Academic Press. This book was released on 2019-08-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Modeling in Physiology and Medicine, Second Edition, develops a clear understanding of the fundamental principles of good modeling methodology. Sections show how to create valid mathematical models that are fit for a range of purposes. These models are supported by detailed explanation, extensive case studies, examples and applications. This updated edition includes clearer guidance on the mathematical prerequisites needed to achieve the maximum benefit from the material, a greater detail regarding basic approaches to modeling, and discussions on non-linear and stochastic modeling. The range of case study material has been substantially extended, with examples drawn from recent research experience. Key examples include a cellular model of insulin secretion and its extension to the whole-body level, a model of insulin action during a meal/oral glucose tolerance test, a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials. Covers the underlying principles of good quantitative modeling methodology, with applied biomedical engineering and bioscience examples to ensure relevance to students, current research and clinical practice Includes modeling data, modeling systems, linear and non-linear systems, model identification, parametric and non-parametric models, and model validation Presents clear, step-by-step working plus examples and extensive case studies that relate concepts to real world applications Provides end-of-chapter exercises and assignments to reinforce learning
Author : Marek Darowski
Publisher : Nova Science Publishers
ISBN 13 : 9781608762125
Total Pages : 0 pages
Book Rating : 4.7/5 (621 download)
Download or read book Comprehensive Models of Cardiovascular and Respiratory Systems written by Marek Darowski and published by Nova Science Publishers. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to spread and make easier the use of comprehensive modelling for research, educational and clinical applications. Flexible and modular numerical, physical and hybrid models developed to assess patho-physiology of cardiovascular and respiratory systems are the subject of the book. The models discussed in the book are effective and easy to use tools to simulate circulatory and respiratory systems, their interactions and their mechanical support. The models can be applied to analyse data, predict the trend of selected variables not routinely measured and to identify critical variables to be monitored. Spreading of comprehensive modelling can offer to physicians and engineers powerful tools to analyse complex phenomena and interactions involving circulatory and respiratory systems along with their mechanical assistance. The complexity of the circulatory and respiratory systems makes their analysis very difficult or sometimes impossible in clinical environment.
Author : Aly Farag
Publisher : Springer
ISBN 13 : 9780387721491
Total Pages : 1142 pages
Book Rating : 4.7/5 (214 download)
Download or read book Deformable Models written by Aly Farag and published by Springer. This book was released on 2007-08-02 with total page 1142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set on Deformable Models: Biomedical and Clinical Applications & Theory and Biomaterial Applications provides a wide cross-section of the methods and algorithms of variational and PDE methods in biomedical image analysis. The chapters are written by well-known researchers in this field, and the presentation style goes beyond an intricate abstraction of the theory into real application of the methods and description of the algorithms that were implemented. As such these chapters will serve the main goal of the editors of these two volumes in bringing down to earth the latest in variational and PDE methods in modeling of soft tissues. Overall, the thirty-one chapters in the two volumes provide an elegant crosssection of the theory and application of variational and PDE approaches in medical image analysis. Graduate students and researchers at various levels of familiarity with these techniques will find the two volumes very useful for understanding the theory and algorithmic implementations. In addition, the various case studies provided demonstrate the power of these techniques in clinical applications. Researchers at various levels will find these chapters useful to understand the theory, algorithms, and implementation of many of these approaches.
Author : Peter Coveney
Publisher : Oxford University Press, USA
ISBN 13 : 0199658188
Total Pages : 294 pages
Book Rating : 4.1/5 (996 download)
Download or read book Computational Biomedicine written by Peter Coveney and published by Oxford University Press, USA. This book was released on 2014-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Biomedicine unifies the different strands of a broad-ranging subject to demonstrate the power of a tool that has the potential to revolutionise our understanding of the human body, and the therapeutic strategies available to maintain and protect it.
Author : John D. Newell
Publisher : Elsevier Health Sciences
ISBN 13 : 0323795021
Total Pages : 162 pages
Book Rating : 4.3/5 (237 download)
Download or read book Developing the Digital Lung written by John D. Newell and published by Elsevier Health Sciences. This book was released on 2022-09-13 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting recent major advances in the field of artificial intelligence, Developing the Digital Lung, From First Lung CT to Clinical AI, by Dr. John Newell, is your go-to reference for all aspects of applied artificial intelligence in lung disease development, including application to clinical medicine. It provides a unique overview of the field, beginning with a review of the origins of artificial intelligence in the mid-1970s and progressing to its application to clinical medicine in the early 2020s. Organized based on the four stages of development, this practical, easy-to-use resource helps you effectively apply artificial intelligences to lung imaging. Traces the development of precise quantitative CT of diffuse lung disease through the use of applied AI, leading to faster effective diagnosis of patients with lung disease. Reviews CT manufacturers, models and scanning protocol used to produce the 3D digital maps of the lungs. Discusses how the data processed by AI algorithms can produce measures of emphysema, air trapping, and airway wall thickening in subjects with COPD and measures of pulmonary fibrosis and traction bronchiectasis in idiopathic pulmonary fibrosis (IPF). Demonstrates the differences between reactive machine AI and limited memory AI methods. Includes comprehensive case studies and current information on cloud computing.
Author : Mark A. Atherton
Publisher : WIT Press
ISBN 13 : 1845640969
Total Pages : 305 pages
Book Rating : 4.8/5 (456 download)
Download or read book Repair and Redesign of Physiological Systems written by Mark A. Atherton and published by WIT Press. This book was released on 2008-07-15 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume the author highlights the role of engineering and relevant mathematics in medicine. Like engineering systems, human physiology can wear out or fail to an extent where it requires a clinical interventionist to repair or even redesign the system. There is a long tradition amongst clinicians of working with engineers and mathematicians, and this volume continues the theme with modern developments. Hence chapters deal with vascular surgery planning, cardiac and vascular devices, immunotherapeutics, plus nasal and dental repair. More generically, some of these chapters relate to preserving the integrity of the human 'surface structure', as well as the challenges in computer modeling the complexities and multiscale nature of the human physiome.
Author : Juan Carlos Gomez-Verjan
Publisher : Springer Nature
ISBN 13 : 3030896013
Total Pages : 214 pages
Book Rating : 4.0/5 (38 download)
Download or read book Principles of Genetics and Molecular Epidemiology written by Juan Carlos Gomez-Verjan and published by Springer Nature. This book was released on 2022-01-28 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers some of the most novel genetic and genomic concepts in epidemiology, such as geospatial statistics and systems biology from a clinical point of view by explaining molecular applications with accessible human studies. Featuring a comprehensive table of contents, it includes chapters from genomics and epidemiology surveillance to transcriptomics and alternative splicing principles. Across 17 well-organized chapters, this book meets attempt to explain easily to clinicians and students with basic principles of the genetics, genomics, molecular biology and its applications to epidemiology and public health. The text is distinct from other literature on the market because it covers useful genomic tools applied in epidemiology for clinicians who may not be experts in this branch of health science. Principles of Genetics and Molecular Epidemiology demystifies the idea that biomedicine is far from being applied in both epidemiology and clinical practice.
Author : Tianzi Jiang
Publisher : Springer Science & Business Media
ISBN 13 : 3642157041
Total Pages : 751 pages
Book Rating : 4.6/5 (421 download)
Download or read book Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2010 written by Tianzi Jiang and published by Springer Science & Business Media. This book was released on 2010-09 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-volume set LNCS 6361, 6362 and 6363 constitutes the refereed proceedings of the 13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010, held in Beijing, China, in September 2010. Based on rigorous peer reviews, the program committee carefully selected 251 revised papers from 786 submissions for presentation in three volumes. The first volume includes 84 papers organized in topical sections on computer-aided diagnosis, planning and guidance of interventions, image segmentation, image reconstruction and restoration, functional and diffusion-weighted MRI, modeling and simulation, instrument and patient localization and tracking, quantitative image analysis, image registration, computational and interventional cardiology, and diffusion tensor MR imaging and analysis.
Author : Marinus te Pas
Publisher : John Wiley & Sons
ISBN 13 : 0470962968
Total Pages : 340 pages
Book Rating : 4.4/5 (79 download)
Download or read book Systems Biology and Livestock Science written by Marinus te Pas and published by John Wiley & Sons. This book was released on 2011-09-23 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology. Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.
Author : Bin He
Publisher : Springer Science & Business Media
ISBN 13 : 0387499636
Total Pages : 332 pages
Book Rating : 4.3/5 (874 download)
Download or read book Modeling & Imaging of Bioelectrical Activity written by Bin He and published by Springer Science & Business Media. This book was released on 2010-07-03 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in the field and comment on the future direction in this fast developing line of research.
Author : Nicholas Ayache
Publisher : Springer
ISBN 13 : 3540757570
Total Pages : 1044 pages
Book Rating : 4.5/5 (47 download)
Download or read book Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007 written by Nicholas Ayache and published by Springer. This book was released on 2007-11-22 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is part of a two-volume set that constitute the refereed proceedings of the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007. Coverage in this first volume includes diffusion tensor imaging and computing, cardiac imaging and robotics, image segmentation and classification, image guided intervention and robotics, innovative clinical and biological applications, brain atlas computing, and simulation of therapy.
