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Cholinergic Mechanisms In The Central Nervous System
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Book Synopsis Cholinergic Mechanisms in the Central Nervous System by : Yng-shiuh Sheu
Download or read book Cholinergic Mechanisms in the Central Nervous System written by Yng-shiuh Sheu and published by . This book was released on 1969 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Drugs and cholinergic mechanisms in the CNS Central Nervous System by :
Download or read book Drugs and cholinergic mechanisms in the CNS Central Nervous System written by and published by . This book was released on 1970 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cholinergic Mechanisms: From Molecular Biology to Clinical Significance by : J. Klein
Download or read book Cholinergic Mechanisms: From Molecular Biology to Clinical Significance written by J. Klein and published by Elsevier. This book was released on 1996-12-18 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a comprehensive update and overview of the field of cholinergic transmission as presented by some thirty distinguished investigators who were recruited for their task from Germany, Great Britain, Canada, USA, Sweden, Israel, France and Italy. Exciting new discoveries, described in this volume, are due to recent methodological breakthroughs. These discoveries throw new light on many areas of cholinergic mechanisms.
Book Synopsis Cholinergic Mechanisms in the Developing Central Nervous System of Normal and Sensory-deprived Rats by : Gabriel Joseph Maletta
Download or read book Cholinergic Mechanisms in the Developing Central Nervous System of Normal and Sensory-deprived Rats written by Gabriel Joseph Maletta and published by . This book was released on 1967 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Central Cholinergic Mechanisms and Adaptive Dysfunctions by : Man Singh
Download or read book Central Cholinergic Mechanisms and Adaptive Dysfunctions written by Man Singh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although serious interest in studying the role of central cho linergic processes in psychopathology is just beginning to emerge, experimental literature on the part played by cholinergic mechanisms in brain behavior. reiations is quite extensive. During the past thirty years, cholinergic research has contributed significantly to the characterization and differentiation of adaptive mechanisms in volved in input selection, perception, cortical, autonomic and behav ioral activation, learning, memory, and inhibitory control of behav ioral outputs. To say that dysfunction of one or more of these mech anisms may be at the root of neuropsychiatric illnesses such as schiz ophrenia would be stating the obvious. This book examines the part cholinergic processes might play in dysfunctions of the adaptive processes involved in higher brain func tions and their significance for the pathogenesis, classification, etiology, and treatment of psychopathological conditions. In a series of wide ranging reviews of the available information, the subject is discussed from a variety of perspectives, using data derived from both experimental and clinical research. The purpose is not so much to determine whether cholinergic excess or deficiency is causal in this or that neuropsychiatric syndrome, but rather to try to understand the disease mechanisms in terms of adaptive processes in which cholinergic systems seem to play an important part.
Book Synopsis Cholinergic Function and Dysfunction by : A. Claudio Cuello
Download or read book Cholinergic Function and Dysfunction written by A. Claudio Cuello and published by Elsevier. This book was released on 1993 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a comprehensive update of central cholinergic mechanisms from their most molecular aspects to possible clinical applications modifying cholinergic neurotransmission. A considerable number of high-calibre scientists from several continents contributed to this volume.
Author :Alexander G. Karczmar Publisher :Springer Science & Business Media ISBN 13 :038746526X Total Pages :698 pages Book Rating :4.3/5 (874 download)
Book Synopsis Exploring the Vertebrate Central Cholinergic Nervous System by : Alexander G. Karczmar
Download or read book Exploring the Vertebrate Central Cholinergic Nervous System written by Alexander G. Karczmar and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic ? eld attracts, and merits, our intense attention. These considerations underlie the signi? cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the ? eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.
Book Synopsis The Role of the Central Nervous System Cholinergic Mechanisms in Behavior and Learning by : Perry Black
Download or read book The Role of the Central Nervous System Cholinergic Mechanisms in Behavior and Learning written by Perry Black and published by . This book was released on 1966 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: The principal purpose of this study was to investigate the possible differential effects of LSD as a function of procedural variations in performance of delayed response tasks. In general, LSD was found to impair delayed response performance in the monkey. From the standpoint of dose-effect relationships, the results suggest a positive correlation between magnitude of dose and extent of functional impairment. A tendency toward rapidly developing tolerance was observed. A 'placebo effect' in response to the control agent (sterile water) was encountered in a significant number of monkeys.
Book Synopsis Brain Cholinergic Mechanisms by : Sukumar Vijayaraghavan
Download or read book Brain Cholinergic Mechanisms written by Sukumar Vijayaraghavan and published by Frontiers Media SA. This book was released on 2016-01-22 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much of our understanding of brain physiology has focused on what one might call, first order processes. These essentially include the primary synaptic mechanisms underlying excitation (mainly glutamate) and inhibition (mainly GABA). Our attention has focused on how the balance of excitation and inhibition regulates the timing, patterns, and extent of information flow across various circuits. A lot less is understood regarding second order processes that sculpt and modify these primary interactions. One such modulatory transmitter in the brain is acetylcholine (ACh). The importance of ACh in modulating various behaviors related to learning, memory, and attention has been recognized over the last four decades as has its involvement in various neurodegenerative and psychiatric disorders. However, our understanding of the mechanistic bases for these actions is at its infancy, at best and much remains to be understood. The array of receptor subtypes for nicotinic and muscarinic receptors, their different locations, and complex signal transduction mechanisms remain a puzzle. Transmitter (ACh) release sites and their relationship to receptor loci are poorly understood. Overall, we lack a unifying framework for conceptualizing how disparate actions of the transmitter on receptors lead to circuit modulation and, eventually, influences on cognition. By its very nature, reports on cholinergic signaling are quite scattered, presented in journals across sub-disciplines and in the context of the systems they modulate. Hence, there is need for consolidation of these studies under a single cover that would allow one to compare and contrast the effects of this transmitter across systems and contexts. This special issue represents one such compilation. The issue addresses cholinergic modulation of defined circuits that lead to specific behaviors and consists of a judicious mixture of review articles and primary papers. The articles focus on three aspects of the system: 1) Cellular targets of cholinergic signaling. 2) Receptor mechanisms. 3) Endogenous transmitter distribution and action. While no common mechanism emerges that can explain cholinergic actions on brain functions, on can postulate that the transmitter system is dynamic, modulating the balance of excitation and inhibition in various circuits. This modulation sets up timed network oscillations and it is tempting to speculate that these oscillations form a template for better encoding of afferent inputs. One can broadly envision the role of the cholinergic system as facilitating processes that allow for more efficient acquisition of learning and engraving of memories. Thus, understanding the mechanisms underlying tonic and stimulus-dependent release of ACh and how it alters firing templates of neuronal networks would be the first step towards elucidating its role in learning and memory. This special topics edition provides clues to some of the actions of ACh. It is hoped that the articles allow the reader to extract common themes and potential mechanisms of cholinergic regulation that will lead to elucidation of general principles governing the actions of this important neuromodulator.
Book Synopsis Central Cholinergic Systems and Behaviour by : F DeFeudis
Download or read book Central Cholinergic Systems and Behaviour written by F DeFeudis and published by Elsevier. This book was released on 2012-12-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Central Cholinergic Systems and behavior reviews experimental evidence on the possible involvement of central cholinergic systems in the regulation of animal behavior. More specifically, the book investigates the role of acetylcholine as a transmitter in the mammalian spinal cord and in central nervous function. This text also describes cholinergic involvement in some of the more fundamental processes of central nervous functions and how it may fit into overall cholinergic and non-cholinergic behavioral patterns. This book is organized into seven chapters and begins with an overview of the link between central cholinergic mechanisms and behavior, and then discusses the cholinergic roles in consciousness, emphasizing on the roles of reticular systems in the arousal mechanism. An effort is made to define the cholinergic nature of some spinal mechanisms that are apparently involved in reflexes and posture. An account of the role of cholinergic mechanisms in central respiratory control is also given, along with the function of acetylcholine as an important transmitter at many sites of the central nervous system. The book concludes by analyzing the roles of cholinergic systems in motivated behaviors, emotion, learning, and memory. This book is a valuable resource for students and researchers in fields ranging from physiology to biology and psychiatry.
Book Synopsis The Role of 4-methylpiperidine Analogs of Hemicholinium-3 Cholinergic Mechanisms in the Central Nervous System by : Clark Edward Tedford
Download or read book The Role of 4-methylpiperidine Analogs of Hemicholinium-3 Cholinergic Mechanisms in the Central Nervous System written by Clark Edward Tedford and published by . This book was released on 1986 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effect of Acute and Chronic Administration of Morphine on Cholinergic Mechanisms in the Central Nervous System by : Toby Reva Goldstein
Download or read book Effect of Acute and Chronic Administration of Morphine on Cholinergic Mechanisms in the Central Nervous System written by Toby Reva Goldstein and published by . This book was released on 1978 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cholinergic Mechanisms by : Peter Gaudenz Waser
Download or read book Cholinergic Mechanisms written by Peter Gaudenz Waser and published by . This book was released on 1975 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cholinergic–Monoaminergic Interactions in the Brain by : Larry Butcher
Download or read book Cholinergic–Monoaminergic Interactions in the Brain written by Larry Butcher and published by Elsevier. This book was released on 2012-12-02 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholinergic-Monoaminergic Interactions in the Brain investigates dynamic synaptic mechanisms in the brain and their links to various behaviors and related functional processes. More specifically, it explores neurochemical interactions by focusing on the relationship between cholinergic and monoaminergic mechanisms in the central nervous system. It also presents morphologic data to highlight the importance of structure in understanding function, particularly, that of the neostriatum and the role of acetylcholine and neurochemicals. Organized into six sections comprised of 18 chapters, this volume begins with an overview of various models of cholinergic-monoaminergic and other chemical interactions, based in part on interactive processes that are believed to operate in the peripheral nervous system. The next chapters focus on experimental observations on electrophysiologic and neurochemical interactions in the brain and the functional correlates of such interactions. The discussion then turns to the neurohistochemical and neurobiochemical aspects of cholinergic-monoaminergic interactions, the effects on neostriatal acetylcholine levels, and the synthesis of the cortico-neostriatal and thalamo-neostriatal pathways. The reader is also introduced to the effects of lesion in the globus pallidus, the electrophysiology of interactions, the effects of drugs thought to preferentially affect monoaminergic or related neurotransmission mechanisms on acetylcholine in the brain, and whether dopamine is excitatory or inhibitory upon neostriatal neurons. Finally, the book assesses the significance of central cholinergic-monoaminergic interactions for functional processes, both normal and pathologic. This book is a valuable resource for neuroscientists, pharmacologists, histochemists, behavioral biologists, psychobiologists, and psychologists.
Book Synopsis Cholinergic Mechanisms and Psychopharmacology by : D. Jenden
Download or read book Cholinergic Mechanisms and Psychopharmacology written by D. Jenden and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents a collection of papers which were contributed by participants at a Symposium for Cholinergic Mechanisms and Psycho pharmacology, held in La Jolla, California on March 28-30, 1977. The were chosen to emphasize areas in which there has been substantial topics progress in the past 2-3 years and fall into seven major groups dealingwith: cholinergiC receptors; chemistry, histochemistry and enzymology; cyclic nucleotides and cholinergiC mechanisms; storage, compartmentation and release of acetylcholine; regulatory mechanisms in acetylcholine metab olism; modulation of acetylcholine metabolism; and behavioral and clin ical manifestations of cholinergiC function and dysfunction. Each group contains one or more reviews and a number of shorter contributions de scribing current work. This symposium was the third in a series of which the first two were held in Skokloster, Sweden in 1970 and Boldern, Switzerland in 1974. The Proceedings of the meetings indicate a rapid development of knowledge of cholinergiC mechanisms which for many years lagged behind that of other neurotransmitters and neuroregulators. The inclusion of a large section in the present volume dealing with clinical manifestations of cholinergiC dysfunction reflects one of the most important trends in current research on cholinergiC mechanisms, namely the close inter-relationship and mutual support of basic science and clinical investigation. I hope that this volume will be of value to all those whose work relates to cholinergiC function, at both basic and clinicalleve18, and will continue to stimulate the vigorous exchange of ideas which was such a prominent feature of the Symposium.
Book Synopsis Methods of Behavior Analysis in Neuroscience by : Jerry J. Buccafusco
Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Book Synopsis Central Cholinergic Mechanisms and Adaptive Dysfunctions by : Man Singh
Download or read book Central Cholinergic Mechanisms and Adaptive Dysfunctions written by Man Singh and published by . This book was released on 1985-01-01 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: