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Author : International Cholinergic Symposium
Publisher :
ISBN 13 : 9780444801043
Total Pages : 378 pages
Book Rating : 4.8/5 (1 download)
Download or read book Cholinergic Mechanisms written by International Cholinergic Symposium and published by . This book was released on 1996 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Giancarlo Pepeu
Publisher : Springer Science & Business Media
ISBN 13 : 1468486438
Total Pages : 964 pages
Book Rating : 4.4/5 (684 download)
Download or read book Cholinergic Mechanisms written by Giancarlo Pepeu and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 964 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every three years early Spring witnesses the convening of a small group of neuroscientists from many parts of the world. They are devoted to the study of acetylcholine, the oldest of the known neurotransmitters. To assess the level of knowledge, to take stock of the still unsolved problems, to evaluate the practical meaning of their findings, the cholinologists first met in 1969 in the eerie atmosphere of a snow-covered Swedish forest, the second in the Swiss Alps, the third facing the surf and foam of the Paci fic waves. Finally in March 1980 Florence, her trees burgeoning in the mild rain of March, confronted them with the temptation of her monuments and museums. But the cholinologists bravely dismis sed the temptations and went on with the presentations and discus sions of the many papers which form the present book. The papers describe the most recent development of investiga tions on acetylcholine. They open with an extensive coverage of the developmental and phylogenetic aspects of the cholinergic neurons. The regulation of acetylcholine synthesis, release, post synaptic, electrical and trophic effects in the peripheral chol inergic synapses including ganglia, neuromuscular junction, myen theric plexus and heart is then covered. Special emphasis is given to the cholinergic mechanisms in the eye.
Author : J. Klein
Publisher : Elsevier
ISBN 13 : 0080862349
Total Pages : 376 pages
Book Rating : 4.0/5 (88 download)
Download or read book Cholinergic Mechanisms: From Molecular Biology to Clinical Significance written by J. Klein and published by Elsevier. This book was released on 1996-12-18 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a comprehensive update and overview of the field of cholinergic transmission as presented by some thirty distinguished investigators who were recruited for their task from Germany, Great Britain, Canada, USA, Sweden, Israel, France and Italy. Exciting new discoveries, described in this volume, are due to recent methodological breakthroughs. These discoveries throw new light on many areas of cholinergic mechanisms.
Author : Israel Silman
Publisher : CRC Press
ISBN 13 : 9781135417451
Total Pages : 852 pages
Book Rating : 4.4/5 (174 download)
Download or read book Cholinergic Mechanisms written by Israel Silman and published by CRC Press. This book was released on 2013-04-08 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a cutting-edge profile of research progress in this important field of study, Cholinergic Mechanisms: Function and Dysfunction contains a compilation of the proceedings of the Eleventh ISCM, held in St. Moritz, May 2002. Bringing together 250 contributors from 30 countries, the book presents a comprehensive picture of the cholinergic field. It provides a survey of current understanding of molecular, pharmacological, toxicological, behavioral, and clinical aspects of the cholinergic system. This volume offers a state-of-the-art account of progress in the field from the molecule in the test tube through the cell and the synapse, to the organism and the patient.
Author : Herbert Ladinsky
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (18 download)
Download or read book Cholinergic Mechanisms, Phylogenetic Aspects, Central and Peripheral Synapses, and Clinical Significance written by Herbert Ladinsky and published by . This book was released on 1981 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alexander G. Karczmar
Publisher : Springer Science & Business Media
ISBN 13 : 038746526X
Total Pages : 698 pages
Book Rating : 4.3/5 (874 download)
Download or read book Exploring the Vertebrate Central Cholinergic Nervous System written by Alexander G. Karczmar and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic ? eld attracts, and merits, our intense attention. These considerations underlie the signi? cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the ? eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.
Author : Hermann J. Gertz
Publisher : Springer Science & Business Media
ISBN 13 : 3709175089
Total Pages : 313 pages
Book Rating : 4.7/5 (91 download)
Download or read book Alzheimer’s Disease - From Basic Research to Clinical Applications written by Hermann J. Gertz and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: As human longevity continues to be extended, so will the impact of age-associated dementia on individual lives and society. Alzheimer’s disease as the most common cause of dementia in the elderly remains a sentinal problem and its underlying pathology is still poorly understood. Available therapeutic strategies require considerable refinement and the development of new therapeutic strategies need input from basic research. Thus continued efforts are necessary both to understand basic mechanisms of the condition and to achieve more powerfull therapies. This volume brings together the reports of basic scientists and clinical investigators. The chapters provide a spectrum of information valuable for clinicians and scientists. This issue bridges the gap between laboratory work in basic science and the development of urgently needed therapeutic strategies. Areas presented are the molecular and cellular biology of the disease, pathogenetic mechanisms and potential therapeutic targets, genetics, risk factors, strategies of prevention and treatment as well as practical aspects of medical and social care for patients with Alzheimer’s disease.
Author : M.D. Binder
Publisher : Elsevier
ISBN 13 : 9780080862484
Total Pages : 479 pages
Book Rating : 4.8/5 (624 download)
Download or read book Peripheral and Spinal Mechanisms in the Neural Control of Movement written by M.D. Binder and published by Elsevier. This book was released on 1999-12-17 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, we have witnessed a striking maturation of our understanding of how neurons in the spinal cord control muscular activity and movement. Paradoxically, a host of new findings have revealed an unexpected versatility in the behavior of these well-studied neural elements and circuits. In this volume, the world's leading experts review the current state of our knowledge of motor control, outline their latest results and developments, and delineate the seminal unresolved questions in this vibrant field of research. The volume begins with a commentary and overview of our current understanding of the peripheral and spinal basis of motor control. The remainder of the volume is divided into seven sections, each focused on a different problem. The first chapter in each section provides some historical review and presages the experimental findings and hypotheses that are discussed in subsequent chapters. Topics include the biomechanics of neuromuscular systems, the properties of motoneurons and the muscle units they control, spinal interneurons, pattern generating circuits, locomotion, descending control of spinal circuits, comparative physiology of motor systems, and motor systems neurophysiology studied in man. The book serves as a unique reference volume and should be essential reading for anyone interested in motor systems. Moreover, the volume's comprehensive coverage of a wide range of topics make it an effective textbook for graduate level courses in motor control neurobiology, kinesiology, physical therapy, and rehabilitation medicine.
Author : F.W. Van Leeuwen
Publisher : Elsevier
ISBN 13 : 9780080862422
Total Pages : 529 pages
Book Rating : 4.8/5 (624 download)
Download or read book Neuronal Degeneration and Regeneration: From Basic Mechanisms to Prospects for Therapy written by F.W. Van Leeuwen and published by Elsevier. This book was released on 1998-11-09 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the result of the 20th International Summer School in Brain Research, organized in August 1997 in Amsterdam, by the Netherlands Institute for Brain Research at the Royal Netherlands Academy of Sciences. It is the first book that provides a complete overview of the field of neurodegeneration and regeneration including spinal cord injury, neurodegenerative diseases and therapy. Divided into five sections, the first two sections give an overview of fundamental research on nerve cell death, neuronal survival, neurite outgrowth and guidance. Extensive attention is given to the role of neurotrophins, their receptor tyrosine kinases and cell-adhesion molecules in development and regeneration of the nervous system. The third section of the book is devoted to research involving human neurodegenerative diseases and emerging treatment strategies. Section four focusses on recent advances in the understanding of pathophysiological mechanisms underlying neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases along with prion diseases. Novel insights into the neuropathological hallmarks of these diseases, as well as into transgenic animal models, the involvement of environmental factors, and genomic and mRNA changes that can cause neurodegeneration. The final section of this volume reveals recent developments in the use of cell and gene therapy to treat neurodegenerative disease and lesion-related deficits. Implantation of genetically modified cells, direct gene transfer with viral vectors and the first clinical trials with encapsulated genetically modified cells in patients suffering from amyotrophic lateral scelerosis are examples of new therapeutic strategies treating neurodegenerative diseases. The book is of particular interest to departments of neuroscience, neurological clinics and departments, the pharmalogical industry and medical libraries.
Author : E.A. Mayer
Publisher : Elsevier
ISBN 13 : 0080862470
Total Pages : 545 pages
Book Rating : 4.0/5 (88 download)
Download or read book The Biological Basis for Mind Body Interactions written by E.A. Mayer and published by Elsevier. This book was released on 2000-02-03 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current volume focuses on several key aspects of mind/brain/body interactions in health and disease, including specific examples of interactions between body and brain, mechanisms underlying the response of the system to stressors, the role of early life events in permanently biasing the responsiveness of the system and practical implications of mind body interactions in human disease. The volume on Biological Basis for Mind Body Interactions is organized into 6 major sections, each dealing with a unique aspect of the general topic: After establishing the relationship between mind, brain and emotions, the first section deals with general neurobiological aspects mediating the effect of stress on various organ systems, including the immune and cardiovascular system. The second section covers the topic of how early life stressor can permanently alter responsiveness of the nervous system in animals and in man. The third section deals with influences of the internal environment, mediated by neuroendocrine and visceral afferent pathways on the CNS. The fourth section which deals with influences of body on the brain, focuses on mechanisms involved in perception and modulation of pain. The fifth section deals with influences of the mind/brain on the body, with an emphasis on central and peripheral mechanisms of autonomic control of body functions. The last section deals with a series of practical issues of mind body treatments, including acupuncture, breathing, body work and meditation. In addition, issues such as cost effectiveness and research aspects are discussed. Authors in this last section frequently refer to topics and mechanisms addressed in the early sections, making it a truly integrated volume. The unique aspect of the volume is the integration of state of the art research information on biological and practical aspects of mind/brain/body interactions. It is based on the beliefs of the editors and participants that the traditional separation of mind and body in research and in treatment of human disease is obsolete and needs to be replaced with a new unifying paradigm. Ironically, this evolving paradigm shares many similarities with ancient pre-Cartesian paradigms of health and disease.
Author : Francisco Jose Barrantes
Publisher : Springer
ISBN 13 : 3662402793
Total Pages : 233 pages
Book Rating : 4.6/5 (624 download)
Download or read book The Nicotinic Acetylcholine Receptor written by Francisco Jose Barrantes and published by Springer. This book was released on 2013-12-17 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jahangir Moini
Publisher : Academic Press
ISBN 13 : 0128174250
Total Pages : 770 pages
Book Rating : 4.1/5 (281 download)
Download or read book Functional and Clinical Neuroanatomy written by Jahangir Moini and published by Academic Press. This book was released on 2020-02-21 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional and Clinical Neuroanatomy: A Guide for Health Care Professionals is a comprehensive, yet easy-to read, introduction to neuroanatomy that covers the structures and functions of the central, peripheral and autonomic nervous systems. The book also focuses on the clinical presentation of disease processes involving specific structures. It is the first review of clinical neuroanatomy that is written specifically for nurses, physician assistants, nurse practitioners, medical students and medical assistants who work in the field of neurology. It will also be an invaluable resource for graduate and postgraduate students in neuroscience. With 22 chapters, including two that provide complete neurological examinations and diagnostic evaluations, this book is an ideal resource for health care professionals across a wide variety of disciplines. Written specifically for "mid-level" providers in the field of neurology Provides an up-to-date review of clinical neuroanatomy based on the latest guidelines Provides a logical, step-by-step introduction to neuroanatomy Offers hundreds of full-color figures to illustrate important concepts Highlights key subjects in "Focus On" boxes Includes Section Reviews at critical points in the text of each chapter
Author : Scott Brady
Publisher : Academic Press
ISBN 13 : 0080959016
Total Pages : 1120 pages
Book Rating : 4.0/5 (89 download)
Download or read book Basic Neurochemistry written by Scott Brady and published by Academic Press. This book was released on 2011-11-02 with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475
Author : I.J.A. Urban
Publisher : Elsevier
ISBN 13 : 9780080862446
Total Pages : 652 pages
Book Rating : 4.8/5 (624 download)
Download or read book Advances in Brain Vasopressin written by I.J.A. Urban and published by Elsevier. This book was released on 1999-02-16 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Brain Vasopressin elucidates the functions of the regulatory peptide vasopressin in the nervous system, and reviews the current status of this field at different levels. It deals with the cell biology and anatomy of the neurons that produce vasopressin in the brain, and provides an overview on the receptors of vasopressin and the signal transduction pathways that they activate, including the cellular responses that are triggered by vasopressin. Reviews are presented on the modulation of behavior induced by vasopressin in a number of different contexts, such as sex-linked and steroid-dependent behaviors, social behaviors, and learning and memory. Furthermore, the volume deals with several controversial issues in the field by presenting overlapping chapters from different research groups in order to provide the reader with current views. Highly relevant and useful, for those working on this "first" neuropeptide, and for young investigators entering the field, and in addition, shows how important a multidisciplinary approach is to unravelling the function of a neuropeptide in the brain.
Author : J.A. Reggia
Publisher : Elsevier
ISBN 13 : 9780080862460
Total Pages : 434 pages
Book Rating : 4.8/5 (624 download)
Download or read book Disorders of Brain, Behavior, and Cognition: The Neurocomputational Perspective written by J.A. Reggia and published by Elsevier. This book was released on 1999-09-16 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains selected contributions of papers, many presented at the Second International Workshop on Neural Modeling of Brain Disorders, as well as a few additional papers on related topics, including a wide range of presentations describing computational models of neurological, neuropsychological and psychiatric disorders. It is a unique, comprehensive review of the state-of-the-art of modeling cognitive and brain disorders, appealing to a multidisciplinary audience of clinicians, psychologists, neuroscientists, cognitive scientists, computer scientists, and other neural network researchers. The rest of the book is organized along four main themes, involving memory, neuropsychological, neurological and psychiatric disorders. In general, the cognitive disorders and these psychiatric diseases traditionally regarded as "functional" were modeled along functional lines, while those disorders traditionally viewed as "organic" neurological diseases generally drew more from knowledge of the underlying neurobiology and pathophysiology.
Author : C. Casanova
Publisher : Gulf Professional Publishing
ISBN 13 : 9780444505866
Total Pages : 514 pages
Book Rating : 4.5/5 (58 download)
Download or read book Vision: From Neurons to Cognition written by C. Casanova and published by Gulf Professional Publishing. This book was released on 2001-10-25 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Internationally renowned researchers discuss how the various parts of the brain process and integrate visual signals, providing up to date original findings, reviews, and theoretical proposals on visual processing. This book addresses the basic mechanisms of visual perception as well as issues such as neuronal plasticity, functional reorganization and recovery, residual vision, and sensory substitution. Knowledge of the basic mechanisms by which our brain can analyze, reconstruct, and interpret images in the external world is of fundamental importance for our capacity to understand the nature and causes of visual deficits, such as those resulting from ischemia, abnormal development, neuro-degenerative disorders, and normal aging. It is also essential to our goal of developing better therapeutic strategies, such as early diagnosis, visual training, behavioral rehabilitation of visual functions, and visual implants.
Author : P. Illes
Publisher : Elsevier
ISBN 13 : 9780080862453
Total Pages : 429 pages
Book Rating : 4.8/5 (624 download)
Download or read book Nucleotides and their Receptors in the Nervous System written by P. Illes and published by Elsevier. This book was released on 1999-08-31 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of purinergic mechanisms has for long been focused on the actions of the nucleoside adenosine, whereby the contribution of nucleotides to the signaling systems has been underestimated. Based on the proceedings of a IUPHAR Satellite Conference held in Leipzig, Germany, this book offers a comprehensive update and overview of nucleotide release, the structure and function of nucleotide receptors, nucleotide-metabolizing ecto-enzymes as well as the physiological functions of nucleotides in the nervous system. The physiology and molecular biology of receptors for ATP and other nucleotides are examined, as are the physiology and molecular biology of enzymes that hydrolyze extracellular nucleotides. At present, a pharmacology of the nucleotide signaling system is being developed. Of particular interest is the production of receptor subtype-specific antagonists and of drugs that selectively affect the extracellular lifetime of the nucleotide. An excellent source of reference for institutes of pharmacology, biochemistry, neurology, zoology, and physiology, and for the pharmaceutical industry.
