Chlamydia Biology

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Biology of Chlamydia

Author : Georg Häcker
Publisher : Springer
ISBN 13 : 3319712322
Total Pages : 243 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Biology of Chlamydia by : Georg Häcker

Download or read book Biology of Chlamydia written by Georg Häcker and published by Springer. This book was released on 2018-06-25 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genus Chlamydia encompasses a number of species of obligate intracellular bacteria, including important human pathogens like the most common bacterial agent of sexually transmitted disease. This volume reviews current knowledge of chlamydial biology, covering the unusual structure of the bacteria – which alternate between metabolically almost inactive and fast-dividing forms. It also discusses the ways in which Chlamydia manipulates the host cytoskeleton and subverts the host cell’s defence, and illustrates how genomics have begun to uncover the diversity and complexity of chlamydial strains that look very similar but may cause distinct forms of disease. Further, it describes how techniques are now finally being established that can genetically modify Chlamydia, and discusses why such modification is still very difficult and what progress we can expect. Lastly, it presents our current understanding of chlamydial disease: what do we know about chronic infections, what are the mechanisms of inflammatory damage, and what are the prospects of a vaccine? Written be specialists in these various areas, the book is a valuable work of reference for students and scientists with an interest in the molecular, cellular and immunobiology of these fascinating bacteria.

Chlamydial Infection

Author : C. M. Black
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318023981
Total Pages : 170 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Chlamydial Infection by : C. M. Black

Download or read book Chlamydial Infection written by C. M. Black and published by Karger Medical and Scientific Publishers. This book was released on 2013 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: New insights into one of the world's most common infectious diseases Chlamydiae are obligate intracellular bacteria that cause one of the most common sexually transmitted infectious diseases in the world. The infection disproportionately impacts women and the highest prevalence of infection is found in adolescents. Most chlamydial infections are asymptomatic. Untreated infections are sources of further spread of infection and can lead to serious consequences including pelvic inflammatory disease, infertility and chronic pelvic pain. Chlamydial infections also increase a person's susceptibility to HIV and other STDs. Featuring contributions by internationally recognized experts in epidemiology, infectious disease research and chlamydial biology, this book provides up-to-date reviews from a clinical and public health perspective on chlamydia epidemiology and control programs, genomics and pathogenicity, diagnosis, treatment, host immune responses, and the latest on the search for an effective vaccine. Also included are chapters on the impact of chlamydial infection on specific populations such as the lesbian, gay, bisexual and transgender community, and an update on the outbreak in Europe of the invasive chlamydial infection, lymphogranuloma venereum or LGV. This comprehensive publication is intended for clinicians, public health workers and scientists with interest in sexually transmitted diseases, medical microbiology, infectious diseases and clinical research.

Chlamydia Biology

Author : Ming Tan
Publisher : Caister Academic Press Limited
ISBN 13 : 9781912530281
Total Pages : 0 pages
Book Rating : 4.5/5 (32 download)

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Book Synopsis Chlamydia Biology by : Ming Tan

Download or read book Chlamydia Biology written by Ming Tan and published by Caister Academic Press Limited. This book was released on 2020-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing nineteen chapters this comprehensive book is essential reading for every Chlamydia researcher.

Intracellular Pathogens I

Author : Ming Tan
Publisher : American Society for Microbiology Press
ISBN 13 : 1555816746
Total Pages : 545 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Intracellular Pathogens I by : Ming Tan

Download or read book Intracellular Pathogens I written by Ming Tan and published by American Society for Microbiology Press. This book was released on 2012-09-15 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: A current review of basic research on Chlamydiales biology and pathogenesis in one comprehensive volume. • Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells. • Describes the spectrum of disease caused by an infection including protective and pathologic immune responses. • Describes the latest developments, including genomics and biomathematical modeling, and progress towards genetic tools and a vaccine. • Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers.

The role of viable but non-infectious developmental forms in chlamydial biology

Author : Robert V Schoborg
Publisher : Frontiers E-books
ISBN 13 : 2889193217
Total Pages : 120 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis The role of viable but non-infectious developmental forms in chlamydial biology by : Robert V Schoborg

Download or read book The role of viable but non-infectious developmental forms in chlamydial biology written by Robert V Schoborg and published by Frontiers E-books. This book was released on 2014-11-04 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chlamydiae are Gram-negative, obligate intracellular bacteria with a complex developmental cycle comprising a metabolically less-active, infectious stage, the elementary body (EB), and a metabolically more active stage, the reticulate body (RB). They are responsible for many acute and chronic diseases in humans and animals. In order to play a causative role in chronic diseases, chlamydiae would need to persist and to re-activate within infected cells/tissues for extended periods of time. Persistence in vitro is defined as viable but non-cultivable chlamydiae involving morphologically enlarged, aberrant, and nondividing RBs, termed aberrant bodies (AB). In vitro, alterations of the normal developmental cycle of chlamydiae can be induced by the addition of Interferon-? (IFN-?), tumor necrosis factor-a (TNF-a) and penicillin G exposure as well as amino acid or iron deprivation, monocyte infection and co-infection with viruses. In vivo, key questions include whether or not ABs occur in infected patients and animals and whether such ABs can contribute to prolonged, chronic inflammation, fibrosis, and scarring through continuing stimulation of the host immune system known from diseases such as trachoma, pelvic inflammatory disease, reactive arthritis and atherosclerosis. To date, the direct causal role in the pathogenesis of chlamydial infection and persistence in vivo has been questioned since there was no tractable animal model of chlamydial persistence so far. A very recent study was able to establish an experimental animal model of in vivo persistence, when C. muridarum vaginally-infected mice were gavaged with amoxicillin. Amoxicillin treatment induced C. muridarum to enter the persistent state in vivo. Recent in vivo data from patients indicate that viable but non-infectious developmental stages are present in the genital tract of chronically-infected women and that the gastrointestinal tract might be a reservoir for persistent chlamydial infections at other sites.

Chlamydia

Author : Richard Scott Stephens
Publisher :
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Chlamydia by : Richard Scott Stephens

Download or read book Chlamydia written by Richard Scott Stephens and published by . This book was released on 1999 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chlamydiae and Chlamydial Infections

Author : Svetoslav P. Martinov
Publisher : CRC Press
ISBN 13 : 1000796205
Total Pages : 314 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Chlamydiae and Chlamydial Infections by : Svetoslav P. Martinov

Download or read book Chlamydiae and Chlamydial Infections written by Svetoslav P. Martinov and published by CRC Press. This book was released on 2022-09-01 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chlamydiae are a group of obligate intracellular microorganisms with a homogeneous group-specific antigenic structure, and a unique mode of development. The infections caused by them are unprecedented and wide-spread throughout the world, including a broad range of hosts among domestic and animal species and humans, and a variety of clinical manifestations. The uniqueness of chlamydia pathology consists mainly in the fact that the agents of the individual diseases are so close in their biological properties that they are represented only by the single genus Chlamydia, which includes all currently recognized species.Although chlamydiae and chlamydial infections were discovered a long time ago, they are still under-researched and relatively unknown to broad circles of microbiologists, virologists, epidemiologists and clinicians. A number of issues relating to molecular biology, pathogenesis, mechanisms of Chlamydia development and their interactions with cells, as well as their genetic conditioning and regulation, remain unclear. The same is true for ambiguities, problems and contradictions related to epidemiology, diagnostic approaches, immunity and vaccines. Based on scientific facts and the analysis of literature, and the experience of the author, Chlamydiae and Chlamydial Infections attempts to shed light on the cited problems, in terms of modern microbiology, cell biology and molecular biology. The scientific topics discussed include:• Biological, morphological and antigenic properties of Chlamydia spp• Genes, genomic structure and genetic regulations• Conventional diagnostic methods and examinations• Detection and differentiation of Chlamydia organisms by DNA detection systems• Clinical forms and manifestations and drug therapy• Pathology• Epidemiological peculiarities of Chlamydia ─ induced diseases in animals and humans• Immunity and vaccines

The Hidden Affliction

Author : Simon Szreter
Publisher : Rochester Studies in Medical H
ISBN 13 : 1580469612
Total Pages : 452 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis The Hidden Affliction by : Simon Szreter

Download or read book The Hidden Affliction written by Simon Szreter and published by Rochester Studies in Medical H. This book was released on 2019 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multidisciplinary collection of essays on the relationship of infertility and the "historic" STIS--gonorrhea, chlamydia, and syphilis--producing surprising new insights in studies from across the globe and spanning millennia.

Atlas of Sexually Transmitted Diseases and AIDS E-Book

Author : Stephen A. Morse
Publisher : Elsevier Health Sciences
ISBN 13 : 0702047643
Total Pages : 389 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Atlas of Sexually Transmitted Diseases and AIDS E-Book by : Stephen A. Morse

Download or read book Atlas of Sexually Transmitted Diseases and AIDS E-Book written by Stephen A. Morse and published by Elsevier Health Sciences. This book was released on 2010-09-17 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Atlas of Sexually Transmitted Diseases and AIDS, 4th Edition, by Drs. Stephen A. Morse, King K. Holmes, Adele A. Moreland, MD, and Ronald C. Ballard, provides you with an exclusive gallery of STD and AIDS images so you can better diagnose and treat these diseases. Approximately 1,100 unique images – most in full color and 30% new to this edition – depict the clinical signs associated with each type of infection. You’ll also find expert guidance on new vaccines, screening techniques, treatment guidelines, and best practices in the field. Get expert advice on the tests available to reach a definitive diagnosis and review therapeutic options, treatment guidelines, prevention strategies, and management of complications. Access appendices on the selection and evaluation of diagnostic tests, quality control, and test technologies. Effectively diagnose all types of STDs and HIV/AIDS with approximately 1,100 images—most in full color and more than 30% new to this edition―that depict the epidemiology as well as the clinical manifestations of these diseases. Effectively utilize new vaccines for HPV and Hepatitis B, new screening tests for Chlamydia, new drugs under development, new treatment guidelines and best practices in HIV screening, and much more.

Microbiology Of Chlamydia

Author : Almen L. Barron
Publisher : CRC Press
ISBN 13 : 1000013014
Total Pages : 293 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Microbiology Of Chlamydia by : Almen L. Barron

Download or read book Microbiology Of Chlamydia written by Almen L. Barron and published by CRC Press. This book was released on 2019-06-04 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1988, this book offers a full, comprehensive guide into microbiology of Chlamydia and its relationship with our bodies. Carefully compiled and filled with a vast repertoire of notes, pictures, and references this book serves as a useful reference for Students of Medicine, and other practitioners in their respective fields.

Chlamydia Trachomatis

Author : Amanda Claire Brown
Publisher :
ISBN 13 : 9781493996940
Total Pages : 289 pages
Book Rating : 4.9/5 (969 download)

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Book Synopsis Chlamydia Trachomatis by : Amanda Claire Brown

Download or read book Chlamydia Trachomatis written by Amanda Claire Brown and published by . This book was released on 2019 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores cutting-edge methods to work with the notoriously difficult, but highly prevalent, obligate intracellular pathogen, Chlamydia trachomatis. These include techniques to identify Chlamydia trachomatis in patient samples, ranging from simple point-of-care tests to whole genome sequencing; methods for propagation of strains in both cell culture and animal models; techniques to manipulate Chlamydia trachomatis in molecular genetic methodologies; a high-throughput screening method for testing new potential drugs against intracellular bacteria; a screen for antibiotic resistance; methods for labeling and enumeration; and descriptions of genotyping technologies, as well as dual RNA-Seq transcriptional profiling. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative, practical, and relevant, Chlamydia trachomatis: Methods and Protocols serves as an ideal reference for scientists searching for a better understanding of the pathogen, allowing for the development of improved treatment regimens and the discovery of new drugs.

Human Emerging and Re-emerging Infections

Author : Sunit Kumar Singh
Publisher : John Wiley & Sons
ISBN 13 : 1118644646
Total Pages : 2365 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Human Emerging and Re-emerging Infections by : Sunit Kumar Singh

Download or read book Human Emerging and Re-emerging Infections written by Sunit Kumar Singh and published by John Wiley & Sons. This book was released on 2015-11-09 with total page 2365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Chlamydia pneumoniae

Author : Herman Friedman
Publisher : Springer Science & Business Media
ISBN 13 : 0306487411
Total Pages : 296 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Chlamydia pneumoniae by : Herman Friedman

Download or read book Chlamydia pneumoniae written by Herman Friedman and published by Springer Science & Business Media. This book was released on 2006-01-27 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chlamydia pneumoniae is a bacteria that is most commonly known for causing colds and pneumonia. However, researchers have recently found a link between C. pneumoniae and atherosclerosis, a clogging of the arteries that causes heart attack and stroke. In addition, ongoing research is showing that certain strains may play a role in asthma, multiple sclerosis, Alzheimer's disease, and arthritis. This volume, part of the Infectious Agents and Pathogenesis series, is a complete portrait of C. pneumoniae and what is currently known about it.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biology of the Chlamydia

Author : Lynn Dorman Cunningham
Publisher :
ISBN 13 :
Total Pages : 184 pages
Book Rating : 4.:/5 (128 download)

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Book Synopsis Biology of the Chlamydia by : Lynn Dorman Cunningham

Download or read book Biology of the Chlamydia written by Lynn Dorman Cunningham and published by . This book was released on 1984 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbiology and pathogenesis of Chlamydia, Coxiella, and Rickettsia

Author : Rey Carabeo
Publisher : Frontiers Media SA
ISBN 13 : 2832551394
Total Pages : 223 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Microbiology and pathogenesis of Chlamydia, Coxiella, and Rickettsia by : Rey Carabeo

Download or read book Microbiology and pathogenesis of Chlamydia, Coxiella, and Rickettsia written by Rey Carabeo and published by Frontiers Media SA. This book was released on 2024-07-08 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obligate intracellular parasitism is the associated with genome reduction, which is the process of reconfiguring the genome through systematic elimination of genetic loci deemed unnecessary. The end-result is an increasing dependence on the host for various factors essential for growth, such as nutrients and a protective intracellular replicative niche. The extreme genome reduction that some of the obligate intracellular bacteria have undergone, while maintaining viability and virulence has revealed the level of adaptability, including a plethora of survival strategies that more often than not functionally converge to modulate similar host cell processes, such as cytoskeletal dynamics, vesicular transport, and pathogen recognition, among others. With the advent of molecular genetic approaches, and in the case of Coxiella, growth in axenic media, the field of obligate intracellular pathogen research has progressed rapidly in the past five years, redefining obligate intracellular parasitism as the field transitions from descriptive to mechanism-based research. An emerging theme is the adaptability and ingenuity of this class of pathogens. Genome reduction prioritizes survival, but because this occurs within a host, there is also the need to maintain virulence. As such, survival strategies become intertwined, and likely inseparable from virulence strategies. The purpose of this Special Topics Issue is to bring together in one volume review articles from experts in the field. This issue will have a broad scope. Articles will describe the current state of knowledge in genetics and genomics, metabolism, cell biology of infection, immune evasion, and vaccine design. Importantly, cutting-edge information will also be discussed in the context of past seminal findings, and future directions of research. Overall, this Special Topics Issue should serve as a valuable reference to colleagues and those new to the field of obligate intracellular pathogens research. We welcome submission of review and mini-review articles on the following topics: • Genome structure • Development of genetic tools • Molecular mechanisms of adhesion, invasion, and other early events in infection • Establishment of the intracellular niche • Niche interactions with organelles • Translocation of effectors • Metabolism and metabolic adaptations • Gene regulation during stress response • Pathogen recognition and immune evasion strategies • Innate and adaptive immunity during infection • Experimental models

Advances in Chlamydiaceae Research and Application: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481612239
Total Pages : 61 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Advances in Chlamydiaceae Research and Application: 2012 Edition by :

Download or read book Advances in Chlamydiaceae Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Chlamydiaceae Research and Application / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Chlamydiaceae in a concise format. The editors have built Advances in Chlamydiaceae Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chlamydiaceae in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Chlamydiaceae Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.