Childhood Idiopathic Nephrotic Syndrome as a Podocytopathy

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Childhood Idiopathic Nephrotic Syndrome as a Podocytopathy by : Samuel N. Uwaezuoke

Download or read book Childhood Idiopathic Nephrotic Syndrome as a Podocytopathy written by Samuel N. Uwaezuoke and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Idiopathic nephrotic syndrome is the commonest manifestation of glomerular disease in children. The syndrome is characterized by massive proteinuria, hypoalbuminemia, generalized edema, and hyperlipidemia. Although genetic or congenital forms are now well recognized, nephrotic syndrome is largely acquired. The latter form can be idiopathic or primary (the causes are unknown) and secondary (the causes are known renal or non-renal diseases). Idiopathic nephrotic syndrome consists of the following glomerulonephritides: minimal change nephropathy (MCN), focal segmental glomerulosclerosis (FSGS), membranoproliferative glomerulonephritis (MPGN), mesangial proliferative glomerulonephritis (MesPGN), and membranous nephritis (MN). The etiopathogenesis of nephrotic syndrome has evolved through several hypotheses ranging from immune dysregulation theory and increased glomerular permeability theory to the current concept of podocytopathy. Podocyte injury is now thought to be the basic pathology in the syndrome. The book chapter aims to highlight the mechanisms underlying the pathogenesis of nephrotic syndrome as a podocytopathy.

Nephrotic Syndrome in Pediatric Patients

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Publisher : Frontiers Media SA
ISBN 13 : 2889452980
Total Pages : 87 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Nephrotic Syndrome in Pediatric Patients by : Agnieszka Swiatecka-Urban

Download or read book Nephrotic Syndrome in Pediatric Patients written by Agnieszka Swiatecka-Urban and published by Frontiers Media SA. This book was released on 2017-10-10 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nephrotic syndrome (NS) - characterized by heavy glomerular protein loss (proteinuria), edema, hypoalbuminemia, and hyperlipidemia - has diverse causes and frequently leads to chronic kidney disease. This E-book encompasses articles on a variety of topics in NS, including a historical perspective on understanding and treatment of NS, followed by state-of-the-art reviews of the molecular pathomechanisms, clinical outcomes, as well as current and emerging treatment strategies for NS. We hope that this comprehensive review will help to reduce the gaps between the research and the day-to-day care of patients with NS and inspire new research efforts towards updating and expanding the treatment armamentarium for the future.

Glomerulonephritis and Nephrotic Syndrome

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Publisher : BoD – Books on Demand
ISBN 13 : 1789843138
Total Pages : 126 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Glomerulonephritis and Nephrotic Syndrome by : Thomas Rath

Download or read book Glomerulonephritis and Nephrotic Syndrome written by Thomas Rath and published by BoD – Books on Demand. This book was released on 2019-10-30 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic kidney disease is a worldwide disease affecting up to 4% of the population. In many cases, glomerulonephritis is the underlying disease leading to kidney failure. One hallmark of glomerulonephritis is proteinuria, which may in its most severe form lead to nephrotic syndrome. In seven chapters, this book puts light on different aspects related to the pathophysiology and clinical aspects of glomerulonephritis. In addition, chapters dealing with the importance of biomarkers in patients with glomerulonephritis will be beneficial for the open-minded reader. Nevertheless, new insights in renal rehabilitation in patients with chronic kidney disease will be provided.

Nephrotic Syndrome in Children

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Publisher : Frontiers Media SA
ISBN 13 : 2889740552
Total Pages : 126 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Nephrotic Syndrome in Children by : Bilal Aoun

Download or read book Nephrotic Syndrome in Children written by Bilal Aoun and published by Frontiers Media SA. This book was released on 2022-01-13 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Podocytopathy

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318026514
Total Pages : 274 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Podocytopathy by : Z.-H. Liui

Download or read book Podocytopathy written by Z.-H. Liui and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-16 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.

Silva's Diagnostic Renal Pathology

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Publisher : Cambridge University Press
ISBN 13 : 1316613984
Total Pages : 691 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Silva's Diagnostic Renal Pathology by : Xin J. Zhou

Download or read book Silva's Diagnostic Renal Pathology written by Xin J. Zhou and published by Cambridge University Press. This book was released on 2017-03-02 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.

Nephrotic Syndrome in Children - ECAB - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 8131239411
Total Pages : 121 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Nephrotic Syndrome in Children - ECAB - E-Book by : RN Srivastava

Download or read book Nephrotic Syndrome in Children - ECAB - E-Book written by RN Srivastava and published by Elsevier Health Sciences. This book was released on 2014-12-11 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nephrotic Syndrome in Children - ECAB - E-Book

Glomerulonephritis

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Publisher : Springer
ISBN 13 : 9783319493787
Total Pages : 0 pages
Book Rating : 4.4/5 (937 download)

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Book Synopsis Glomerulonephritis by : Howard Trachtman

Download or read book Glomerulonephritis written by Howard Trachtman and published by Springer. This book was released on 2019-04-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook serves as a convenient, state-of-the-art and comprehensive resource on the pathogenesis, diagnosis, and treatment of glomerular diseases. Clinical approaches, modalities and challenges are provided, along with new developments since the publication of Kidney Disease Improving Global Outcomes (KDIGO): Glomerulonephritis. Chapters dedicated to glomerular diseases mirror the current classification schemes used by Nephrologists and Pathologists and will include definition and natural history, epidemiology, clinical manifestations, pathology, diagnosis, differential diagnosis, treatment (algorithms when appropriate), prognosis and future prospects and current direction of research. Contributing authors consist of internationally renowned glomerulonephritis experts, renal pathologists and clinical nephrologists who are engaged in the management of glomerular diseases in clinical pediatric and internal medicine practices. Glomerulonephritis fills a considerable knowledge gap for general nephrologists, providers involved with the care of patients with glomerular diseases, and researchers. It should also be of value to medical students, interns, residents and fellows, as well as all clinicians engaged in medical education.

Lupus Nephritis

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Publisher : Oxford University Press
ISBN 13 : 0199568057
Total Pages : 343 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Lupus Nephritis by : Edmund J. Lewis

Download or read book Lupus Nephritis written by Edmund J. Lewis and published by Oxford University Press. This book was released on 2010-11-04 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated and revised, this new edition reflects the numerous advances in clinical management of patients in the last decade, including new understanding of pathogenesis, a new classification and the considerable advances in therapeutic options for the disease.

Consensus Statement

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Publisher :
ISBN 13 :
Total Pages : 15 pages
Book Rating : 4.:/5 (963 download)

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Book Synopsis Consensus Statement by :

Download or read book Consensus Statement written by and published by . This book was released on 1999 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Red Book

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Publisher : Amer Academy of Pediatrics
ISBN 13 : 9781581101942
Total Pages : 992 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Red Book by : American Academy of Pediatrics. Committee on Infectious Diseases

Download or read book Red Book written by American Academy of Pediatrics. Committee on Infectious Diseases and published by Amer Academy of Pediatrics. This book was released on 2006 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Reliable and clinically useful information on the manifestations, etiology, epidemiology, diagnosis, and treatment of some 200 childhood infectious diseases. The new 27th edition has been thoroughly revised and updated to help you stay in step with the latest developments and recommendations. And it has been expanded with a wealth of must-know new clinical content in key areas like active and passive immunization; care of children in special circumstances; management of specific conditions such as anthrax, smallpox, influenza, and pneumococcal infections; and much more."--Publisher description.

Oxford Textbook of Clinical Nephrology

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Publisher : Oxford University Press
ISBN 13 : 0191017655
Total Pages : 3045 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Textbook of Clinical Nephrology by : Neil N. Turner

Download or read book Oxford Textbook of Clinical Nephrology written by Neil N. Turner and published by Oxford University Press. This book was released on 2015-10-29 with total page 3045 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Treatment of Primary Glomerulonephritis

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Publisher : OUP Oxford
ISBN 13 : 0191008117
Total Pages : 511 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Treatment of Primary Glomerulonephritis by : Claudio Ponticelli

Download or read book Treatment of Primary Glomerulonephritis written by Claudio Ponticelli and published by OUP Oxford. This book was released on 2009-05-14 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary glomerulonephritis is a common renal disease which may eventually lead to chronic renal failure. Treatment of glomerulonephritis is difficult. In particular the use of glucocorticoids and immunosuppressive drugs require expertise, knowledge of the drugs, and careful monitoring of the patient. Paradoxically, the treatment of glomerulonephritis has become even more complicated in the recent years, after the introduction of a number of newer immunosuppressive drugs. Extensively updated since publication of the first edition in 1997, this comprehensive yet concise guide to the treatment of even the most complex patients with primary glomerular diseases is full of practical information collected and organized in an easy-to-read manner. It encompasses the possible treatments of the different types of primary glomerulonephritis, including diseases intrinsic to the kidney of unknown or uncertain aetiology. Each of the main chapters is devoted to a single primary glomerulonephritis and follows a similar format to allow easy access of information. The book contains not only an evidence-based review of the topic, but also practical recommendations from internationally recognized experts in the field.

Management of Chronic Kidney Disease

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Publisher : Springer Nature
ISBN 13 : 3031420454
Total Pages : 594 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Management of Chronic Kidney Disease by : Mustafa Arıcı

Download or read book Management of Chronic Kidney Disease written by Mustafa Arıcı and published by Springer Nature. This book was released on with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Approaches to Chronic Kidney Disease

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Publisher : Springer Nature
ISBN 13 : 3030830829
Total Pages : 448 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Approaches to Chronic Kidney Disease by : Jerry McCauley

Download or read book Approaches to Chronic Kidney Disease written by Jerry McCauley and published by Springer Nature. This book was released on 2021-10-18 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic kidney disease (CKD) is a major global public health problem, affecting nearly one in seven adults in the United States alone. It is a disease that integrates chronic illness at several levels, and the progressive condition is associated with high rates of co-morbidity. This text provides a comprehensive, current state-of-the art review of this field, serving as a valuable resource for primary care providers and non-nephrology clinicians that treat patients with CKD. It is comprised of 24 chapters focused on specific aspects of the disease. The first 2 chapters provide a bit of background on the disease, describing the anatomy and physiology of the kidney as well as the definition and epidemiology of the disease. The following 3 chapters discuss the detection, prevention and progression of the disease. The next 6 chapters describe the relationship of the disease with other conditions and most common co-morbidities such as diabetes and hypertension. The chapters, that follow focus on the CKD associated complications and the CKD within special populations such as the elderly and minorities as well as dietary restrictions and drug dosing. The book concludes with discussion on preparation for renal replacement therapy and preemptive organ transplantation as an alternative to dialysis in the management of the advanced CKD. Written by experts in the field, Approach to Chronic Kidney Disease is a comprehensive guide for clinicians, especially primary care providers including residents and fellows in training, who take care of chronic kidney disease patients. It is also a useful tool for researchers dealing with this challenging field.

Podocyte Pathology and Nephropathy

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Publisher : Frontiers Media SA
ISBN 13 : 2889197107
Total Pages : 98 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Podocyte Pathology and Nephropathy by : Barbara Lewko

Download or read book Podocyte Pathology and Nephropathy written by Barbara Lewko and published by Frontiers Media SA. This book was released on 2015-11-30 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of the pathogenesis of diabetic nephropathy (DN) has advanced considerably in the last few years. Much has been learned about the natural history, the relative lack of significance of microalbuminuria in reflecting underlying pathological change, questionable effects of ACEs and ARBs on the progression of nephropathy, the emergence of new biomarkers such as Cystatin and the role of cytokines, inflammatory molecules and adhesion molecules. Podocytes, the cells with limited ability to replenish and to repair, play a pivotal role in glomerular filtration. In recent years these cells have become the focus for research on pathogenesis of DN as well as other nephropathies. A recent review from the NIH has identified new insights into the pathophysiology, the genetics and the role of the podocytes and some of the important new metabolic pathways such as mTOR or autophagy which may be targeting the podocyte. Knowledge is emerging about the role of podocyte as a part of immune system and about the role of growth factors and cytokines in regulation of podocyte functions. Presented in this e-book articles highlight recent advances in our understanding of the pathogenesis of kidney pathology and the role of podocytes in this process.

Role of Monocytes in the Pathogenesis of Idiopathic Nephrotic Syndrome of Childhood

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Publisher :
ISBN 13 :
Total Pages : 366 pages
Book Rating : 4.:/5 (963 download)

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Book Synopsis Role of Monocytes in the Pathogenesis of Idiopathic Nephrotic Syndrome of Childhood by : Siew Peng Chen

Download or read book Role of Monocytes in the Pathogenesis of Idiopathic Nephrotic Syndrome of Childhood written by Siew Peng Chen and published by . This book was released on 2002 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: